Correlation Between Posterior Crossbite and Risk of Obstructive Sleep Apnea

Correlation Between Posterior Crossbite and Risk of Obstructive Sleep Apnea: A Questionnaire-Based Analysis

Correlation Between Posterior Crossbite and Risk of Obstructive Sleep Apnea

Study Overview

• Status: Not yet recruiting
• Conditions: Crossbite Teeth
• Intervention / Treatment: Other: Interventions; Other: Comparator

Detailed Description

Understanding the correlation between posterior crossbite and OSA risk is essential for early detection and prevention. Pediatric dentists and orthodontists are uniquely positioned to identify craniofacial risk factors and initiate early intervention.

Screening tools such as OSA-18 can help identify children at risk and facilitate timely referral for multidisciplinary management. Furthermore, evaluating this association will contribute to improving clinical decision-making and patient outcomes.

Aim of study:

To assess the correlation between posterior crossbite and the risk of obstructive sleep apnea in children using the OSA-18 questionnaire.

• Study Type: Observational
• Enrollment (Estimated): 420

Contacts and Locations

• Study Contact: Name: Marwa A. Salmoon, Ph.D; Phone Number: 01016555055; Email: maasalmoon@msa.edu.eg

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child
• Accepts Healthy Volunteers: N/A

• Sampling Method: Non-Probability Sample

Study Population

Children with posterior crossbite Patients without posterior crossbite, or Normative OSA-18 scores / low-risk groups

Description

Inclusion Criteria:

• Children in mixed dentition stage aged 6-12 years
• Presence of posterior crossbite

Exclusion Criteria:

• Syndromic patients
• Previous orthodontic treatment
• Chronic respiratory or neurological disorders Matching criteria and allocation ratio

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
intervention; Screening using the OSA-18 (Obstructive Sleep Apnea-18) questionnaire	Other: Interventions; Screening using the OSA-18 (Obstructive Sleep Apnea-18) questionnaire
comparator; Patients without posterior crossbite, or Normative OSA-18 scores / low-risk groups	Other: Comparator; Patients without posterior crossbite, or Normative OSA-18 scores / low-risk groups

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Risk or presence of obstructive sleep apnea (OSA) based on OSA-18 scores	questionnaire	2 months

Collaborators and Investigators

• Sponsor: October University for Modern Sciences and Arts
• Investigators: Study Director: Sally M Mosallam, Master Degree, MSA University; Principal Investigator: Ahmed Ayman, MSA University; Principal Investigator: Mohamed Hesham, MSA University

Study record dates

Study Major Dates

• Study Start (Estimated): April 1, 2026
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): June 1, 2026

Study Registration Dates

• First Submitted: April 25, 2026
• First Submitted That Met QC Criteria: April 25, 2026
• First Posted (Actual): May 1, 2026

Study Record Updates

• Last Update Posted (Actual): May 1, 2026
• Last Update Submitted That Met QC Criteria: April 25, 2026
• Last Verified: April 1, 2026

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Investigative Techniques; Methods
• Other Study ID Numbers: 4-2026

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No