Skin Hydration and Facial Aging in Women Aged 30-60: An Observational Correlational Study Using Bioimpedance Analysis (SHFA-30-60)

May 27, 2026 updated by: Olga Ias, IAS Skin Care

Skin Hydration and Facial Aging: A Cross-Sectional Correlational Observational Study Using BT-Analyze Bioimpedance Assessment Across Seven Facial Zones in Women Aged 30-60 Years

This study investigates whether skin hydration levels are related to how old the skin looks. Thirty women aged 30 to 60 years will attend a single visit at a licensed esthetic practice in Florida. Skin moisture will be measured at seven points on the face using the BT-Analyze device. Photographs will be taken and evaluated by a blinded expert cosmetologist using a standard aging scoring system. The study will determine whether women with lower skin hydration tend to show more visible signs of aging.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Skin hydration is maintained through hyaluronic acid, natural moisturizing factor (NMF), and the lipid barrier of the stratum corneum. Dehydration activates matrix metalloproteinases (MMPs) which degrade collagen and elastin, accelerating visible aging. This cross-sectional observational study will enroll 30 women in three age groups (30-40, 40-50, and 50-60 years). Hydration will be assessed using BT-Analyze across seven facial zones. The primary outcome is the Spearman rank correlation between mean hydration score and modified Glogau visual aging score (0-18 points). Covariates include age, Fitzpatrick skin type, daily water intake, menopausal status, and skincare habits.

Study Type

Observational

Enrollment (Actual)

30

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • United States
    • Florida
      • Winter Garden, Florida, United States, 34787
        • IAS Skin Care

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Non-Probability Sample

Study Population

Women aged 30 to 60 years recruited from a licensed esthetic practice in Florida, United States. Participants are divided into three age groups of 10 women each: 30-40, 40-50, and 50-60 years.

Description

Inclusion Criteria:

Female, aged 30 to 60 years Willing to attend one study visit without makeup No cosmetics applied for at least 4 hours prior to the visit Able to acclimate in controlled indoor environment for 20 minutes Signed written informed consent

Exclusion Criteria:

Active dermatological conditions (eczema, psoriasis, rosacea in flare) Injectable cosmetic procedures within the past 6 months Systemic medications affecting skin condition (oral retinoids, systemic corticosteroids) Pregnancy or lactation Uncontrolled systemic conditions known to significantly affect skin (e.g., uncontrolled diabetes mellitus)

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Group 1 - Ages 30-40
Women aged 30 to 40 years (n=10)
Other: BT-Analyze Bioimpedance Measurement
Non-invasive skin hydration measurement using BT-Analyze bioimpedance device at seven standardized facial zones. No therapeutic intervention is administered.
Group 2 - Ages 40-50
Women aged 40 to 50 years (n=10)
Other: BT-Analyze Bioimpedance Measurement
Non-invasive skin hydration measurement using BT-Analyze bioimpedance device at seven standardized facial zones. No therapeutic intervention is administered.
Group 3 - Ages 50-60
Women aged 50 to 60 years (n=10)
Other: BT-Analyze Bioimpedance Measurement
Non-invasive skin hydration measurement using BT-Analyze bioimpedance device at seven standardized facial zones. No therapeutic intervention is administered.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Spearman Correlation Between BT-Analyze Mean Score and Modified Glogau Visual Aging Score
Time Frame: At single study visit (Day 1)
Spearman rank correlation coefficient (rs) between mean BT-Analyze hydration score (mean of seven facial zones, 0-65 units) and total modified Glogau visual aging score (0-18 points) assessed by a blinded expert cosmetologist.
At single study visit (Day 1)

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
BT-Analyze Score Comparison Across Age Groups
Time Frame: At single study visit (Day 1)
Kruskal-Wallis comparison of mean BT-Analyze hydration scores between three age groups (30-40, 40-50, 50-60 years).
At single study visit (Day 1)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

IAS Skin Care

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 1, 2026

Primary Completion (Actual)

May 13, 2026

Study Completion (Actual)

May 24, 2026

Study Registration Dates

First Submitted

April 27, 2026

First Submitted That Met QC Criteria

April 27, 2026

First Posted (Actual)

May 4, 2026

Study Record Updates

Last Update Posted (Actual)

June 1, 2026

Last Update Submitted That Met QC Criteria

May 27, 2026

Last Verified

May 1, 2026

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • IAS-SKIN-2026-001

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Skin Aging

Clinical Trials on BT-Analyze Bioimpedance Measurement

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Sri Lanka

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe