Joint Attention Processing in Social Threat Scenarios
The Proactive and Joint Attention Processing Characteristics of Children With Autism Induced by Social Threat Scenarios
Study Overview
Status
Conditions
Study Type
Enrollment (Actual)
Contacts and Locations
Study Locations
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Sichuan
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Chengdu, Sichuan, China, 611731
- School of Foreign Languages, University of Electronic Science and Technology of China
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Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Child
Accepts Healthy Volunteers
Sampling Method
Study Population
Population composition: TD and ASD. TD: 3-10 years old, with normal vision and corrected vision, hearing, and no social or behavioral problems. ASD: 3-10 years old, diagnosed by a doctor with ASD, normal vision and corrected vision, hearing, etc., but with social and behavioral problems.
Key demographic information: 3-10 years old. TD: 22 males and 6 females. ASD: 24 males and 4 females.
Source and final scale: TD recruited 36 children from Jinhua Primary School and First Kindergarten in Shehong City, Sichuan Province, and ultimately used 28 children. ASD: 52 children from special schools and rehabilitation institutions in some districts and counties of Chengdu were recruited, and 28 were ultimately used.
Description
Inclusion Criteria:
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For ASD group:
- 3 years ≤ age ≤ 10 years;
- a diagnosis of autism spectrum disorder based on clinical symptoms, confirmed using the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) and other auxiliary diagnostic scales, including the Autism Diagnostic Interview-Revised (ADI-R) and the Childhood Autism Rating Scale (CARS);
- further confirmation of ASD symptoms by experimenters with established research reliability using the Autism Diagnostic Observation Schedule, Second Edition (ADOS-2), with severity scores reported;
- absence of comorbid physical diseases or other psychiatric disorders, including normal vision (or corrected-to-normal vision) and normal hearing;
- no receipt of medication, transcranial magnetic stimulation (TMS), or transcranial direct current stimulation (tDCS) within the past three months.
For TD group:The inclusion criterion for the TD group was a score below the cutoff on the Social Responsiveness Scale (SRS).
Exclusion Criteria:
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For ASD group:
- age < 3 years or > 10 years;
- absence of a diagnosis of autism spectrum disorder based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) and other auxiliary diagnostic scales, including the Autism Diagnostic Interview-Revised (ADI-R) and the Childhood Autism Rating Scale (CARS);
- failure to meet diagnostic criteria after confirmation of ASD symptoms by experimenters with established research reliability using the Autism Diagnostic Observation Schedule, Second Edition (ADOS-2);
- presence of comorbid physical diseases or other psychiatric disorders, or problems with vision (or corrected-to-normal vision) and hearing;
- receipt of medication, transcranial magnetic stimulation (TMS), or transcranial direct current stimulation (tDCS) within the past three months.
For TD group:
children were excluded if their scores on the Social Responsiveness Scale (SRS) exceeded the cutoff.
Study Plan
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
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Autism Spectrum Disorder (ASD) Group
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Typically Developing Children (TD) Group
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
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Gaze transitions
Time Frame: The two time windows of 48-56 seconds and 70-80 seconds.
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the number of transitions between face stimuli and unexpected stimuli
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The two time windows of 48-56 seconds and 70-80 seconds.
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The proportion of fixation time
Time Frame: The two time windows of 48-56 seconds and 70-80 seconds.
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The proportion of fixation time on AOI is calculated as the fixation time on AOI divided by the total valid fixation time on the screen within each phase
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The two time windows of 48-56 seconds and 70-80 seconds.
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Activation concentration
Time Frame: The two time windows of 48-56 seconds and 70-80 seconds.
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the concentration of cortical activation during video viewing
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The two time windows of 48-56 seconds and 70-80 seconds.
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Collaborators and Investigators
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Actual)
Study Completion (Actual)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- UESTC-GazeLab-03
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
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