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Joint Attention Processing in Social Threat Scenarios

The Proactive and Joint Attention Processing Characteristics of Children With Autism Induced by Social Threat Scenarios

This study set up two experiments using the free viewing video paradigm. By setting up social threat scenarios induced by humans (Experiment 1) and non social threat scenarios induced by objects (Experiment 2), combined with eye tracking and fNIRS technology, we explored the eye movement patterns and related brain activation characteristics of IJA in children with ASD.

Studieoversigt

Undersøgelsestype

Observationel

Tilmelding (Faktiske)

56

Kontakter og lokationer

Dette afsnit indeholder kontaktoplysninger for dem, der udfører undersøgelsen, og oplysninger om, hvor denne undersøgelse udføres.

Studiesteder

    • Sichuan
      • Chengdu, Sichuan, Kina, 611731
        • School of Foreign Languages, University of Electronic Science and Technology of China

Deltagelseskriterier

Forskere leder efter personer, der passer til en bestemt beskrivelse, kaldet berettigelseskriterier. Nogle eksempler på disse kriterier er en persons generelle helbredstilstand eller tidligere behandlinger.

Berettigelseskriterier

Aldre berettiget til at studere

  • Barn

Tager imod sunde frivillige

Ja

Prøveudtagningsmetode

Ikke-sandsynlighedsprøve

Studiebefolkning

Population composition: TD and ASD. TD: 3-10 years old, with normal vision and corrected vision, hearing, and no social or behavioral problems. ASD: 3-10 years old, diagnosed by a doctor with ASD, normal vision and corrected vision, hearing, etc., but with social and behavioral problems.

Key demographic information: 3-10 years old. TD: 22 males and 6 females. ASD: 24 males and 4 females.

Source and final scale: TD recruited 36 children from Jinhua Primary School and First Kindergarten in Shehong City, Sichuan Province, and ultimately used 28 children. ASD: 52 children from special schools and rehabilitation institutions in some districts and counties of Chengdu were recruited, and 28 were ultimately used.

Beskrivelse

Inclusion Criteria:

-

For ASD group:

  1. 3 years ≤ age ≤ 10 years;
  2. a diagnosis of autism spectrum disorder based on clinical symptoms, confirmed using the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) and other auxiliary diagnostic scales, including the Autism Diagnostic Interview-Revised (ADI-R) and the Childhood Autism Rating Scale (CARS);
  3. further confirmation of ASD symptoms by experimenters with established research reliability using the Autism Diagnostic Observation Schedule, Second Edition (ADOS-2), with severity scores reported;
  4. absence of comorbid physical diseases or other psychiatric disorders, including normal vision (or corrected-to-normal vision) and normal hearing;
  5. no receipt of medication, transcranial magnetic stimulation (TMS), or transcranial direct current stimulation (tDCS) within the past three months.

For TD group:The inclusion criterion for the TD group was a score below the cutoff on the Social Responsiveness Scale (SRS).

Exclusion Criteria:

-

For ASD group:

  1. age < 3 years or > 10 years;
  2. absence of a diagnosis of autism spectrum disorder based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) and other auxiliary diagnostic scales, including the Autism Diagnostic Interview-Revised (ADI-R) and the Childhood Autism Rating Scale (CARS);
  3. failure to meet diagnostic criteria after confirmation of ASD symptoms by experimenters with established research reliability using the Autism Diagnostic Observation Schedule, Second Edition (ADOS-2);
  4. presence of comorbid physical diseases or other psychiatric disorders, or problems with vision (or corrected-to-normal vision) and hearing;
  5. receipt of medication, transcranial magnetic stimulation (TMS), or transcranial direct current stimulation (tDCS) within the past three months.

For TD group:

children were excluded if their scores on the Social Responsiveness Scale (SRS) exceeded the cutoff.

Studieplan

Dette afsnit indeholder detaljer om studieplanen, herunder hvordan undersøgelsen er designet, og hvad undersøgelsen måler.

Hvordan er undersøgelsen tilrettelagt?

Design detaljer

Kohorter og interventioner

Gruppe / kohorte
Autism Spectrum Disorder (ASD) Group
Typically Developing Children (TD) Group

Hvad måler undersøgelsen?

Primære resultatmål

Resultatmål
Foranstaltningsbeskrivelse
Tidsramme
Gaze transitions
Tidsramme: The two time windows of 48-56 seconds and 70-80 seconds.
the number of transitions between face stimuli and unexpected stimuli
The two time windows of 48-56 seconds and 70-80 seconds.
The proportion of fixation time
Tidsramme: The two time windows of 48-56 seconds and 70-80 seconds.
The proportion of fixation time on AOI is calculated as the fixation time on AOI divided by the total valid fixation time on the screen within each phase
The two time windows of 48-56 seconds and 70-80 seconds.
Activation concentration
Tidsramme: The two time windows of 48-56 seconds and 70-80 seconds.
the concentration of cortical activation during video viewing
The two time windows of 48-56 seconds and 70-80 seconds.

Samarbejdspartnere og efterforskere

Det er her, du vil finde personer og organisationer, der er involveret i denne undersøgelse.

Datoer for undersøgelser

Disse datoer sporer fremskridtene for indsendelser af undersøgelsesrekord og resumeresultater til ClinicalTrials.gov. Studieregistreringer og rapporterede resultater gennemgås af National Library of Medicine (NLM) for at sikre, at de opfylder specifikke kvalitetskontrolstandarder, før de offentliggøres på den offentlige hjemmeside.

Studer store datoer

Studiestart (Faktiske)

29. december 2024

Primær færdiggørelse (Faktiske)

4. juni 2025

Studieafslutning (Faktiske)

1. juli 2025

Datoer for studieregistrering

Først indsendt

6. maj 2026

Først indsendt, der opfyldte QC-kriterier

6. maj 2026

Først opslået (Faktiske)

13. maj 2026

Opdateringer af undersøgelsesjournaler

Sidste opdatering sendt (Faktiske)

13. maj 2026

Sidste opdatering indsendt, der opfyldte kvalitetskontrolkriterier

6. maj 2026

Sidst verificeret

1. maj 2026

Mere information

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