- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07612956
Effects of a 4-Week Altitude Training on Sport-Specific Performance, Body Composition, and Cardiac and Pulmonary Function in Adolescent Male Rowers
Effects of a 4-Week Altitude Training on Sport-Specific Performance, Body Composition, and Cardiac and Pulmonary Function in Adolescent Male Rowers: The Potential Role of Maturation
Study Overview
Status
Intervention / Treatment
Study Type
Enrollment (Estimated)
Phase
- Not Applicable
Contacts and Locations
Study Contact
- Name: Ziyue Ou
- Phone Number: +853 8591 2000
- Email: research_ethics@ipm.edu.mo
Study Locations
-
-
Macao
-
Macao, Macao, China
- Recruiting
- Macao Polytechnic University, Faculty of Health Sciences and Sports
-
Contact:
- Chaoran Han
- Phone Number: +853 8591 2000
- Email: hanchaoran1999@outlook.com
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
Accepts Healthy Volunteers
Description
Inclusion Criteria:Male adolescent rowers aged 12-19 years Regularly training and participating in competitive rowing Willing to participate in 4-week altitude training program and follow testing protocol -
Exclusion Criteria:Any cardiovascular, respiratory, hematologic, or musculoskeletal disorders Injury or illness preventing participation in high-intensity rowing training Participation in another high-altitude training program within the last 3 months Any medical contraindication to blood sampling
-
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Other
- Allocation: Non-Randomized
- Interventional Model: Parallel Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Post-PHV group
Participants in the Post-PHV group are adolescent male rowers stratified by biological maturation (PHV offset).
They will undergo the same 4-week high-altitude training program, including aerobic, anaerobic, and sport-specific rowing exercises.
Pre- and post-training measurements of athletic performance, athletic body composition, athletic cardiac and pulmonary function, and hematological markers will be collected.
|
Participants undergo a 4-week altitude training program, including aerobic, anaerobic, and sport-specific rowing exercises.
Both Post-PHV and Mid-PHV groups receive the same training protocol.
Pre- and post-training assessments include athletic performance, athletic body composition, athletic cardiac and pulmonary function, and hematological markers.
Participants are stratified by biological maturation (PHV offset) to explore whether maturity influences training adaptations.
|
|
Experimental: Mid-PHV group
Participants in the Post-PHV group are adolescent male rowers stratified by biological maturation (PHV offset).
They will undergo the same 4-week high-altitude training program, including aerobic, anaerobic, and sport-specific rowing exercises.
Pre- and post-training measurements of athletic performance, athletic body composition, athletic cardiac and pulmonary function, and hematological markers will be collected.
|
Participants undergo a 4-week altitude training program, including aerobic, anaerobic, and sport-specific rowing exercises.
Both Post-PHV and Mid-PHV groups receive the same training protocol.
Pre- and post-training assessments include athletic performance, athletic body composition, athletic cardiac and pulmonary function, and hematological markers.
Participants are stratified by biological maturation (PHV offset) to explore whether maturity influences training adaptations.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Peak Power During Wingate Test
Time Frame: Pre-training and immediately post 4-week altitude training
|
Peak power measured during the Wingate anaerobic test before and after the intervention.
|
Pre-training and immediately post 4-week altitude training
|
|
Maximal Oxygen Uptake
Time Frame: Pre-training and immediately post 4-week altitude training
|
Pre- and post-intervention measurement of VO₂max using standard exercise testing protocol to assess aerobic capacity in adolescent male rowers.
|
Pre-training and immediately post 4-week altitude training
|
|
Mean Power Output During 1500 m Rowing Test
Time Frame: Pre-training and immediately post 4-week altitude training
|
Mean power output measured during the 1500 m rowing ergometer test before and after the intervention.
|
Pre-training and immediately post 4-week altitude training
|
|
Body Weight
Time Frame: Pre-training and immediately post 4-week altitude training
|
Body weight measured before and after the training period.
|
Pre-training and immediately post 4-week altitude training
|
|
Body Fat Percentage
Time Frame: Pre-training and immediately post 4-week altitude training
|
Body fat percentage measured using bioelectrical impedance or other validated method.
|
Pre-training and immediately post 4-week altitude training
|
|
Forced Vital Capacity (FVC)
Time Frame: Pre-training and immediately post 4-week altitude training
|
Forced vital capacity measured using spirometry before and after the intervention.
|
Pre-training and immediately post 4-week altitude training
|
|
Maximal Voluntary Ventilation
Time Frame: Pre-training and immediately post 4-week altitude training
|
MVV measured using standard pulmonary function testing protocol pre- and post-intervention.
|
Pre-training and immediately post 4-week altitude training
|
|
Left Ventricular Volume
Time Frame: Pre-training and immediately post 4-week altitude training
|
Echocardiography measurement of left ventricular end-diastolic and end-systolic volume.
|
Pre-training and immediately post 4-week altitude training
|
|
Ejection Fraction
Time Frame: Pre-training and immediately post 4-week altitude training
|
Echocardiography assessment of left ventricular ejection fraction pre- and post-training.
|
Pre-training and immediately post 4-week altitude training
|
|
Myocardial Thickness
Time Frame: Pre-training and immediately post 4-week altitude training
|
Measurement of interventricular septum and left ventricular posterior wall thickness by echocardiography.
|
Pre-training and immediately post 4-week altitude training
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Muscle Mass
Time Frame: Pre-training and immediately post 4-week altitude training
|
Skeletal muscle mass measured pre- and post-training.
|
Pre-training and immediately post 4-week altitude training
|
|
Red Blood Cell Count
Time Frame: Pre-training and immediately post 4-week altitude training
|
RBC count measured from venous blood samples pre- and post-intervention.
|
Pre-training and immediately post 4-week altitude training
|
|
Hemoglobin
Time Frame: Pre-training and immediately post 4-week altitude training
|
Hemoglobin concentration measured from venous blood samples.
|
Pre-training and immediately post 4-week altitude training
|
|
Hematocrit
Time Frame: Pre-training and immediately post 4-week altitude training
|
Hematocrit levels measured pre- and post-training.
|
Pre-training and immediately post 4-week altitude training
|
|
Erythropoietin
Time Frame: Pre-training and immediately post 4-week altitude training
|
Plasma EPO concentration measured from venous blood samples.
|
Pre-training and immediately post 4-week altitude training
|
Collaborators and Investigators
Sponsor
Study record dates
Study Major Dates
Study Start (Estimated)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Other Study ID Numbers
- FCSD/DPPESS-2026/003
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
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