Influencing Factors on Training Efficacy in Healthy Adults (CHO)

November 20, 2014 updated by: Anne Krieg M.D., Universität des Saarlandes

The Influence of Carbohydrates on Training Efficacy and Health Status in Healthy Adults

The purpose of this study is to investigate the effects of carbohydrate intake on training efficacy and health parameters of an endurance training program in healthy adults.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Carbohydrate availability in endurance exercise seems to attenuate exercise-induced perturbations of cellular homeostasis and consequently diminishes the stimulus for training adaptation. Therefore, a negative relationship with exercise efficacy seems plausible. However, experimental evidence is rare and far from conclusive. Therefore, the present study aims to test the influence of carbohydrate intake on the efficacy of a typical preventive training program.

Study Type

Interventional

Enrollment (Actual)

23

Phase

  • Early Phase 1

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Germany
    • Saarland
      • Saarbrücken, Saarland, Germany, 66012
        • Institute of Sports and Preventive Medicine, Saarland University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

30 years to 65 years (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • no diseases
  • nonsmoker
  • BMI 25-30 kg/m²
  • blood pressure <160/100 mm/Hg
  • unmedicated
  • untrained status
  • V̇O2max < 50 mL/kg/min

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: Randomized
  • Interventional Model: Crossover Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Carbohydrates
50 grams of carbohydrates 4 times a week for each training session
Behavioral: Endurance Training
Other Names:
  • 4 sessions a week at 70 percent heart rate reserve
Placebo Comparator: Control
no carbohydrate intake
Behavioral: Endurance Training
Other Names:
  • 4 sessions a week at 70 percent heart rate reserve

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Maximum oxygen consumption (VO2max)
Time Frame: 24 weeks
VO2max
24 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Numerous serum parameters from venous blood (LDL, HDL, Cholesterol, Triglycerides)
Time Frame: 24 weeks

cardiovascular parameters:

  • LDL
  • HDL
  • Cholesterol
  • Triglycerides
24 weeks
Resting heart rate
Time Frame: 24 weeks
24 weeks
Resting blood pressure
Time Frame: 24 weeks
24 weeks
Body fat (Skinfold thickness)
Time Frame: 24 weeks
Skinfold thickness
24 weeks
Ventilatory anaerobic threshold (VT)
Time Frame: 24 weeks
VT
24 weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Universität des Saarlandes

Investigators

  • Principal Investigator: Tim Meyer, M.D. Prof., Universität des Saarlandes

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

August 1, 2012

Primary Completion (Actual)

December 1, 2013

Study Completion (Actual)

December 1, 2013

Study Registration Dates

First Submitted

September 10, 2013

First Submitted That Met QC Criteria

November 20, 2014

First Posted (Estimate)

November 21, 2014

Study Record Updates

Last Update Posted (Estimate)

November 21, 2014

Last Update Submitted That Met QC Criteria

November 20, 2014

Last Verified

November 1, 2014

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • Saarland University - CHO

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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