- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07626632
Effects of the Tyler Twist Versus Eccentric Exercises
June 1, 2026 updated by: Riphah International University
Effects of the Tyler Twist Versus Eccentric Exercises in Patients With Lateral Epicondylagia
This study aims to compare the effects of the Tyler Twist exercise versus traditional eccentric exercises on pain, grip strength, and functional outcomes in patients diagnosed with lateral epicondylalgia.
The primary objective is to determine which intervention offers greater improvement in clinical symptoms and overall function over a defined treatment period.
Study Overview
Status
Not yet recruiting
Conditions
Intervention / Treatment
Detailed Description
Conservative management is typically the first line of treatment, with eccentric exercises widely recognized for their effectiveness in promoting tendon healing and reducing pain.
The "Tyler Twist," exercise is a variation using the TheraBand FlexBar, that has emerged as a superior potential alternative, that combines both eccentric and concentric loading in a functional and controlled way.
However, direct comparative evidence between the Tyler Twist and conventional eccentric exercises has remained limited.
Study Type
Interventional
Enrollment (Estimated)
38
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Imran Amjad, PhD
- Phone Number: 03324390125
- Email: imran.amjad@riphah.edu.pk
Study Locations
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Punjab Province
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Lahore, Punjab Province, Pakistan, 54000
- Ghurki Hospital Lahore
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Contact:
- Hira Shaukat, Mphill
- Phone Number: 03360405480
- Email: hirabutt7582@gmail.com
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Contact:
- Hira Butt
- Phone Number: 03360405480
- Email: hirabutt7582@gmail.com
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Principal Investigator:
- Hafiza Nukhba SIBGHAT, MSOMPT
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-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Adult
Accepts Healthy Volunteers
No
Description
Inclusion Criteria:
● Males and female patients suffering from lateral epicondylagia in subacute and chronic phase.
- Age between 20yrs-40yrs.
- Patients screened with positive Cozen's test, positive Mill's test, positive Maudsley's test [14].
- NPRS pain score ≥ 4 on activity.
- Tenderness on palpation over the lateral epicondyle of humerus,
- Pain with gripping, Pain with resisted wrist extension.
Exclusion Criteria:
- History of recent trauma or surgery of elbow.
- Acute stage of lateral epicondylagia.
- Corticosteroid injection within the last 3 months.
- Neurological defeciency of the affected limb [16].
- Systemic inflammatory diseases, such as rheumatoid arthritis, lupus, or fibromyalgia.
- Diabetes mellitus (uncontrolled) due to its influence on tendinopathy.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Double
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Tyler Twist Exercises
The Tyler Twist is a specific eccentric exercise using the TheraBand FlexBar, designed to target the extensor carpi radialis brevis (ECRB), which is primarily involved in lateral epicondylalgia.
|
|
|
Active Comparator: Traditional Eccentric Wrist Extensor Exercises
This protocol involves eccentric strengthening of the wrist extensor muscles (primarily ECRB)using a dumbbell (1-2 kg) or wrist cuff weight.
|
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Numeric pain rate scale (NPRS) for pain
Time Frame: 6 weeks
|
To determine the degree of pain that the patient will report, the Numeric Pain Rating Scale (NPRS) will be utilized.
This scale consists of 11 points ranging from 0-10, where zero indicates no pain, five represents moderate pain intensity, and ten signifies severe pain intensity
|
6 weeks
|
|
Handheld dynamometer for grip strength:
Time Frame: 6 weeks
|
For pain-free grip strength assessment, the patient's arm is positioned comfortably with the shoulder adducted and neutrally rotated, the elbow flexed to 90 degrees.20, the forearm in a neutral position, and the wrist in slight extension and ulnar deviation.
The patient is instructed to squeeze as tightly as possible for 3-5 seconds, with multiple trials and an average of three repetitions recorded.
A brief pause is provided between trials to prevent muscle fatigue.
Hand-held dynamometers have been shown to have excellent internal validity and reliability, with reported values of 0.31-0.69 in the upper extremities
|
6 weeks
|
|
Patient-Rated Tennis Elbow Evaluation (PRTEE) for functional disability
Time Frame: 6 weeks
|
The PRTEE questionnaire is one of the most widely-used outcome measures that appreciates elbow
|
6 weeks
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Hira Shaukat, Mphill, Riphah International University
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
General Publications
- Cancela-Cilleruelo I, Rodriguez-Jimenez J, Fernandez-de-Las-Penas C, Cleland JA, Arias-Buria JL. Widespread Pressure Pain Hyperalgesia Is Not Associated With Morphological Changes of the Wrist Extensor Tendon in Unilateral Lateral Epicondylalgia: A Case-Control Study. Phys Ther. 2024 Sep 4;104(9):pzae075. doi: 10.1093/ptj/pzae075.
- Karabinov V, Georgiev GP. Lateral epicondylitis: New trends and challenges in treatment. World J Orthop. 2022 Apr 18;13(4):354-364. doi: 10.5312/wjo.v13.i4.354. eCollection 2022 Apr 18.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Estimated)
June 15, 2026
Primary Completion (Estimated)
October 10, 2026
Study Completion (Estimated)
November 13, 2026
Study Registration Dates
First Submitted
June 1, 2026
First Submitted That Met QC Criteria
June 1, 2026
First Posted (Actual)
June 4, 2026
Study Record Updates
Last Update Posted (Actual)
June 4, 2026
Last Update Submitted That Met QC Criteria
June 1, 2026
Last Verified
June 1, 2026
More Information
Terms related to this study
Other Study ID Numbers
- REC/RCR&AHS/25/0121
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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