A Novel Strategy for Endoscopic Dual-instrument Retrieval of Upper GI Foreign Body

June 14, 2026 updated by: Quan-Lin Li, Shanghai Zhongshan Hospital
We describe a single-center, retrospective case series (n = 10) for the utilization of dual instruments to extract foreign body at physiological narrowing. Foreign bodies that failed to remove with a single instrument or located in physiological narrowing into the duodenal bulb or descending duodenum were considered appropriate for this technique. Informed consent was obtained from all patients before the procedure.

Study Overview

Status

Completed

Conditions

Study Type

Observational

Enrollment (Actual)

10

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • China
      • Shanghai, China
        • Zhongshan Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

In this study, we retrospectively examined the records of 10 patients who underwent endoscopic foreign body extraction at Zhongshan Hospital, Fudan University between January 2018 and January 2026. All patients initially presented to the emergency department and underwent an initial single-instrument endoscopic retrieval attempt. When single-instrument retrieval was unsuccessful or unstable, a dual-instrument endoscopic retrieval technique was subsequently applied. All procedures were performed by a single experienced therapeutic endoscopist.

Description

Inclusion Criteria:

-Consecutive patients who underwent dual-instrument endoscopic retrieval for upper gastrointestinal foreign bodies at our center during the study period.

Exclusion Criteria:

-Patients with incomplete clinical or procedural records. Patients lost to follow-up immediately after the procedure.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
dual-instrument

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Successful Endoscopic Foreign Body Removal Rate
Time Frame: 1 day
Percentage of patients in whom the foreign body is completely removed using the dual-instrument endoscopic retrieval technique without the need for surgical intervention. Success will be assessed by direct endoscopic visualization and procedural records.
1 day

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Procedure-Related Adverse Event Rate
Time Frame: 1 week
Percentage of patients experiencing procedure-related adverse events, including mucosal injury, bleeding, perforation, aspiration, or infection. Adverse events will be assessed based on endoscopic findings, clinical evaluation, and post-procedural medical records.
1 week

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Shanghai Zhongshan Hospital

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

  • 1. Yu S, Wang X, Chen X. Removal of giant spherical foreign body in the esophagus by double-forceps endoscope and double balloon. J Int Med Res. 2020;48(8):0300060520941332. doi:10.1177/0300060520941332 2. Birk M, Bauerfeind P, Deprez P, et al. Removal of foreign bodies in the upper gastrointestinal tract in adults: European society of gastrointestinal endoscopy (ESGE) clinical guideline. Endoscopy. 2016;48(05):489-496. doi:10.1055/s-0042-100456 3. Emara M, Darwiesh E, Refaey M, Galal S. Endoscopic removal of foreign bodies from the upper gastrointestinal tract: 5-year experience. CEG. Published online July 2014:249. doi:10.2147/CEG.S63274

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2018

Primary Completion (Actual)

January 1, 2026

Study Completion (Actual)

June 1, 2026

Study Registration Dates

First Submitted

June 8, 2026

First Submitted That Met QC Criteria

June 14, 2026

First Posted (Actual)

June 16, 2026

Study Record Updates

Last Update Posted (Actual)

June 16, 2026

Last Update Submitted That Met QC Criteria

June 14, 2026

Last Verified

January 1, 2018

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • B2025-789

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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