Visual Prognosis in Non-Penetrating Corneal Blast Injuries

The purpose of this study is to assess visual quality of patients with non-penetrating, non-metallic, stable corneal foreign bodies. Visual quality will be assessed by examining visual acuity, wavefront analysis and contrast sensitivity. Drawings, photographs, and confocal microscopy will be used to document clinical examination of the cornea at baseline and on follow-up examinations.

Study Overview

• Status: Completed
• Conditions: Corneal Foreign Body Following Blast Injury
• Intervention / Treatment: Behavioral: Visual quality of patients with corneal eye injuries

• Study Type: Observational
• Enrollment (Anticipated): 40

Contacts and Locations

Study Locations

• United States
  • District of Columbia
    • Washington, District of Columbia, United States, 20307
      • Walter Reed Army Medical Center

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

US Army patients age 18 years and older prsenting with corneal foreign bodies from non-penetrating ocular blast injuries

Description

Inclusion Criteria:

• Informed consent
• Access to medical care at Walter Reed Army Medical Center
• Age 18 years or older
• Corneal foreign bodies from blast injuries
• Available for evaluation at Walter Reed

Exclusion Criteria:

• Residual, recurrent or active ocular disease in the designated eye as determined by exam and history.
• Penetrating ocular trauma or injury to the posterior segment
• Prior history of ocular surgery
• Any physical or mental impairment that would preclude participation in any of the examinations.
• Any ocular abnormality other than corneal foreign bodies that have any impact on vision (i.e. other abnormalities from trauma such as retinal detachment, corneal laceration, traumatic cataract, or abnormalities unrelated to trauma such as herpes.

Study Plan

How is the study designed?

Collaborators and Investigators

• Sponsor: Walter Reed Army Medical Center
• Investigators: Principal Investigator: Dain Brooks, MD, Ophthalmology Service, Walter Reed Army Medical Center

Study record dates

Study Major Dates

• Study Start: November 1, 2004
• Study Completion (Actual): May 1, 2007

Study Registration Dates

• First Submitted: December 20, 2006
• First Submitted That Met QC Criteria: December 20, 2006
• First Posted (Estimate): December 21, 2006

Study Record Updates

• Last Update Posted (Estimate): December 30, 2010
• Last Update Submitted That Met QC Criteria: December 29, 2010
• Last Verified: December 1, 2010

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Barotrauma; Wounds and Injuries; Foreign Bodies; Blast Injuries
• Other Study ID Numbers: WRAMC WU# 04-23010