Association Between Oral Hypofunction, Sarcopenia and Social Frailty in Community-dwelling Older Adults (OSSF)

June 15, 2026 updated by: Chang Gung University of Science and Technology

Association Between Oral Hypofunction, Sarcopenia, and Social Frailty in Community-Dwelling Older Adults

Previous studies have provided a preliminary understanding of the likelihood of sarcopenia and the prevalence of sarcopenia in the elderly in the community. due to the interaction between physiological and social factors, this study aims to conduct a correlation study on muscle mass, oral function and social frailty in the elderly living in the community.

This study，the Makizako social frailty screening index questionnaire and the Tilburg Frailty Indicator will be used to assess the social frailty status of the study participants. Correlation analysis with sarcopenia and oral dysfunction was also conducted to better understand the interaction between nutrition, physiology, and social connection in the elderly, which will be helpful for formulating relevant policies and promoting healthy aging in the future in extremely elderly countries.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Actual)

200

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Taiwan
      • Taoyuan, Taiwan
        • Chang Gung University of Science and Technology

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Older Adult

Accepts Healthy Volunteers

Yes

Sampling Method

Non-Probability Sample

Study Population

Care centers in Taoyuan City and various districts of New Taipei City

Description

Group A-Inclusion Criteria:

  • 65 years old or above
  • general public or institutionalized for 3 months or more
  • those who accept the experimental design and are willing to sign the consent form
  • dietary sources are oral intake
  • those who are diagnosed as having possible sarcopenia by researchers

Group B-Inclusion Criteria:

  • 65 years old or above
  • general public or institutionalized for 3 months or more
  • those who accept the experimental design and are willing to sign the consent form
  • dietary sources are oral intake
  • those who were determined by researchers to be non-probable sarcopenia

Group A、B-Exclusion Criteria:

  • comorbidities, critical illness, pre- and post-major surgery, cancer, renal failure, liver failure, kidney disease, liver disease, malignant tumors within the past five years, inflammatory conditions (c-reactive protein >10mg/dL)
  • severely malnourished people
  • long-term force-feeding

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Group A
Possible sarcopenia
Other: Non interventional study
NON
Group B
Non-possible sarcopenia
Other: Non interventional study
NON

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Based on the results of empirical research on sarcopenia in Asian countries, a diagnostic consensus was established.
Time Frame: Baseline
  • The cut-off point for abnormal grip strength is less than 28 kg for men and less than 18 kg for women
  • 6-meter walking speed less than 1.0 second/meter
  • 5-time chair stand test greater than or equal to 12 seconds
  • Short physical performance battery, SPPB greater than or equal to 9 points The above will be combined to determine whether sarcopenia is possible.
Baseline

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Chang Gung University of Science and Technology

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

November 14, 2025

Primary Completion (Actual)

June 4, 2026

Study Completion (Actual)

June 4, 2026

Study Registration Dates

First Submitted

June 10, 2026

First Submitted That Met QC Criteria

June 15, 2026

First Posted (Actual)

June 22, 2026

Study Record Updates

Last Update Posted (Actual)

June 22, 2026

Last Update Submitted That Met QC Criteria

June 15, 2026

Last Verified

June 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 202500861A3
  • ZRRPF3Q0061 (Other Grant/Funding Number: Chang Gung University of Science and Technology)

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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