Development of Pain Management JITAI Content in Multiple Sclerosis and Spinal Cord Injury

June 16, 2026 updated by: Anna Kratz, University of Michigan

Development of Pain Management Just-In-Time Adaptive Interventions (JITAI) Content in Multiple Sclerosis and Spinal Cord Injury

Just-In-Time Adaptive Interventions (JITAIs) offer a framework for delivering personalized behavioral support using time-varying data to optimize the timing and type of intervention content. This project will develop the foundational components of a JITAI tailored to adults with chronic pain and either MS or SCI by drawing on symptom self-management content from existing programs (PainGuide, MyMSToolkit, and MySCIToolkit). Intervention content and delivery parameters will be refined through stakeholder engagement via structured interviews to ensure relevance, acceptability, and feasibility.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

14

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • United States
    • Michigan
      • Ann Arbor, Michigan, United States, 48109
        • Recruiting
        • University of Michigan
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

Adults with chronic pain and either MS or SCI.

Description

Inclusion Criteria:

  • Able to read and converse fluently in English
  • Multiple sclerosis (MS) or Spinal Cord Injury (SCI) diagnosis
  • Chronic pain ( ≥ 4 on average using a 0-10 NRS for 3-month duration)
  • Access to an internet connected device with a camera and microphone for participating in virtual interview/focus group.

Exclusion Criteria:

  • Cognitive or other impairment (e.g., hearing) that precludes study participation.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Interviews
This study will utilize a community engaged research approach to facilitate collaboration between participants and researchers in developing JITAI content to support pain self-management. Participants will have been formally diagnosed with either multiple sclerosis (MS) and/or spinal cord injury (SCI). Participants will review proposed JITAI content and provide feedback only to the study team.
Other: Push Notification Content
This project will develop the foundational components of a JITAI (push notification content) tailored to adults with chronic pain and either MS or SCI by drawing on symptom self-management content from existing programs (PainGuide, MyMSToolkit, and MySCIToolkit). Intervention content and delivery parameters will be refined through stakeholder engagement via structured interviews with participants to ensure relevance, acceptability, and feasibility.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Preference
Time Frame: 1 day
Participant preferences for the JITAI push notification content and delivery assessed via interviews. The primary outcome will be assessed with qualitative data analyses, which will be used to inform push notification content for a JITAI to support chronic pain self-management in adults with MS and adults with SCI.
1 day

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Michigan

Collaborators

National Center for Complementary and Integrative Health (NCCIH)

Investigators

  • Principal Investigator: Anna Kratz, University of Michigan

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 25, 2026

Primary Completion (Estimated)

July 1, 2026

Study Completion (Estimated)

July 1, 2026

Study Registration Dates

First Submitted

June 16, 2026

First Submitted That Met QC Criteria

June 16, 2026

First Posted (Actual)

June 23, 2026

Study Record Updates

Last Update Posted (Actual)

June 23, 2026

Last Update Submitted That Met QC Criteria

June 16, 2026

Last Verified

June 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • HUM00290625
  • K24AT012644-02 (U.S. NIH Grant/Contract)

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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