Effect of SugarLock® Peanut Skin Extract on Postprandial Blood Glucose Control

Assessing the Impact of SugarLock® Peanut Skin Extract on Postprandial Blood Glucose Control

The objective of this study is to investigate the effects of pre-meal supplementation with SugarLock® peanut skin extract and white kidney bean extract on reducing or delaying postprandial blood glucose elevation and glycemic fluctuations, and to evaluate their potential as nutritional supplements for postprandial glycemic management.

Study Overview

• Status: Recruiting
• Conditions: Blood Sugar (Glucose) Control; Postprandial Glucose
• Intervention / Treatment: Dietary supplement: Water; Dietary supplement: Peanut skin extract; Dietary supplement: White kidney bean extract

Detailed Description

This study is a single-center, randomized 2×3 crossover human trial designed to evaluate the effect of SugarLock® peanut skin extract on postprandial glycemic regulation. Healthy adults aged over 18 years with fasting blood glucose below 100 mg/dL and without type 1 or type 2 diabetes will be enrolled. Each participant will complete three test visits, with at least a 48-hour washout interval, while wearing a continuous glucose monitoring system (CGM). On each test day, after fasting for at least 10 hours, participants will consume either two peanut skin extract capsules, two white kidney bean extract capsules, or water only 15 minutes before eating white rice containing 50 g of carbohydrates. Postprandial glucose responses will then be continuously monitored for 3 hours to assess the effects on blood glucose elevation and glycemic fluctuation.

• Study Type: Interventional
• Enrollment (Estimated): 30
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Fang-Pei Chen, Ph.D.; Phone Number: 3310 +886-06-2785123; Email: fpchen@mail.cjcu.edu.tw

Study Locations

• Taiwan
  • Tainan, Taiwan, 711301
    • Recruiting
    • Chang Jung Christian University
    • Contact: Fang-Pei Chen, Ph.D.; Phone Number: 3310 +886-06-2785123; Email: fpchen@mail.cjcu.edu.tw
    • Principal Investigator: Fang-Pei Chen, Ph.D.

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Adults aged 18 years or older;
• Fasting blood glucose level < 100 mg/dL;
• Individuals without type 1 or type 2 diabetes.

Exclusion Criteria:

• Women who are pregnant, breastfeeding, or planning to become pregnant during the study period;
• Individuals with chronic gastrointestinal diseases (such as irritable bowel syndrome [IBS], inflammatory bowel disease [IBD], chronic diarrhea, celiac disease, short bowel syndrome, ulcers, colorectal cancer, etc.), a history of epilepsy or seizures, psychiatric disorders, malignant tumors, endocrine disorders, liver or kidney disease, or other major organic diseases;
• Individuals with a history of gastrointestinal surgery or organ transplantation;
• Individuals who have taken medications or supplements affecting blood glucose or insulin within the past three months;
• Individuals allergic to peanuts or white kidney beans;
• Full-time employees in the same department as the principal investigator, and students directly taught by the principal investigator during the current semester.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Crossover Assignment
• Masking: None (Open Label)

Number of Arms

3

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Placebo Comparator: Blank control; consume 150 mL water 15 minutes before eating white rice containing 50 g of carbohydrates	Dietary supplement: Water; consume 150 mL water
Experimental: SugarLock® peanut skin extract; consume two SugarLock® peanut skin extract capsules (200 mg/capsule) with 150 mL water 15 minutes before eating white rice containing 50 g of carbohydrates	Dietary supplement: Peanut skin extract; consume two peanut skin extract capsules (200 mg/capsule) with 150 mL water; Other Names: SugarLock®
Active Comparator: White kidney bean extract; consume two White kidney bean extract capsules (250 mg/capsule) with 150 mL water 15 minutes before eating white rice containing 50 g of carbohydrates	Dietary supplement: White kidney bean extract; consume two White kidney bean extract capsules (250 mg/capsule) with 150 mL water

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Interstitial fluid glucose level (mg/dL)	Postprandial glucose responses will then be continuously monitored by continuous glucose monitoring system (CGM) for 3 hours	at 3 hours after eating white rice

Collaborators and Investigators

• Sponsor: TCI Co., Ltd.
• Investigators: Principal Investigator: Fang-Pei Chen, Chang Jung Christian University

Study record dates

Study Major Dates

• Study Start (Actual): July 9, 2026
• Primary Completion (Estimated): September 30, 2026
• Study Completion (Estimated): October 31, 2026

Study Registration Dates

• First Submitted: July 9, 2026
• First Submitted That Met QC Criteria: July 9, 2026
• First Posted (Actual): July 15, 2026

Study Record Updates

• Last Update Posted (Actual): July 15, 2026
• Last Update Submitted That Met QC Criteria: July 9, 2026
• Last Verified: July 1, 2026

More Information

Terms related to this study

• Keywords: SugarLock; peanut skin extract; postprandial glycemic regulation
• Additional Relevant MeSH Terms: Inorganic Chemicals; Anions; Ions; Electrolytes; Hydroxides; Alkalies; Oxides; Oxygen Compounds; Water
• Other Study ID Numbers: A-ER-115-167

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No