Search results for SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[InterventionSearch] Placebo - ICH GCP - Clinical Trials Registry

ICH GCP | Clinical Trials Registry

Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[InterventionSearch] Placebo



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#
NCTID/Status
Study
Last Changed
55651
NCT00622947
Terminated
The Antidepressant Effect of Right Temporal Low Frequency rTMS Compared to Sham
Conditions: Depressive Disorder
Intervention: Right Temporal Low Frequency (1 Hz) RTMS, Sham-rTMS
March 14, 2019
55652
NCT00851045
Completed
Ph II Trial of a Novel Anti-angiogenic Agent in Combination With Chemotherapy for the Second-line Treatment of Metastatic Colorectal Cancer
Conditions: Colorectal Cancer (CRC)
Intervention: Irinotecan, 5-Fluorouracil (bolus), 5-Fluorouracil (infusional), Leucovorin Calcium, CT-322, Bevacizumab, Bevacizumab Placebo (saline Solution)
September 23, 2015
55653
NCT01126437
Completed
Comparison of Tiotropium in the HandiHaler Versus the Respimat in Chronic Obstructive Pulmonary Disease
Conditions: Pulmonary Disease, Chronic Obstructive
Intervention: Tiotropium 18 Mcg, Tiotropium 1.25 Mcg (2 Actuations/day), Tiotropium 2.5 Mcg (2 Actuations/day)
May 20, 2014
55654
NCT00715689
Completed
Dose Study in Growth Hormone Deficient Adults Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC126-0083
Conditions: Growth Hormone Disorder; Adult Growth Hormone Deficiency
Intervention: NNC126-0083, NNC126-0083, NNC126-0083, NNC126-0083, Placebo, Placebo, Placebo, Placebo
February 6, 2017
55655
NCT00736281
Terminated
Sublingual Immunotherapy for Food Allergy
Conditions: Food Allergies
Intervention: Food Drops: Food Allergens (peptides)
June 16, 2016
55656
NCT03950336
Not yet recruiting
Prebiotics and Diet to Reduce "Leaky" Gut in First Degree Relatives of Crohn's Disease Patients
Conditions: Healthy First Degree Relatives of Crohn's Disease Patients
Intervention: Prebiotics, Low N-6 PUFA Diet, Maltodextrin, Control Diet
May 15, 2019
55657
NCT03484507
Recruiting
Parasitic Ulcer Treatment Trial Pilot
Conditions: Acanthamoeba Keratitis
Intervention: Chlorhexidine, Povidone-Iodine, Prednisolone Sodium Phosphate, Hydroxypropyl Methylcellulose, Prednisolone Sodium Phosphate, Hydroxypropyl Methylcellulose
July 31, 2018
55658
NCT03649711
Recruiting
Chronic Kidney Disease (CKD) Platelet Study
Conditions: Chronic Kidney Diseases; Heart Attack; Stroke, Ischemic
Intervention: Ticagrelor 90mg, Clopidogrel 75mg, Aspirin 81 Mg
November 18, 2019
55659
NCT03354741
Not yet recruiting
Stimulation of Acupuncture Points by Athermic Laser Therapy for the Prevention of Chemotherapy Induced Nausea and Vomiting in Children
Conditions: Children; Chemotherapy-induced Nausea and Vomiting; Malignant Tumor
Intervention: Laser Therapy
September 5, 2018
55660
NCT00643201
Completed
Efficacy and Safety Study of Apixaban for the Treatment of Deep Vein Thrombosis or Pulmonary Embolism
Conditions: Venous Thrombosis
Intervention: Enoxaparin, Warfarin, Placebo For Apixaban, Placebo For Enoxaparin, Placebo For Warfarin, Apixaban
April 17, 2014
55661
NCT01169233
Completed
Operational Evaluation of a Photic Countermeasure to Improve Alertness, Performance, and Mood During Nightshift Work on a 105-day Simulated Human Exploration Mission to Mars
Conditions: Sleep; Alertness; Fatigue
Intervention: Bright Light Box
April 28, 2015
55662
NCT03741062
Recruiting
Effects of Laser Stimulation on Wound Healing of Human Palatal Tissue
Conditions: Healing Surgical Wounds; Pain Measurement
Intervention: J. Morita AdvErl Evo Er:YAG Laser, Control
August 12, 2019
55663
NCT03339362
Completed
FAcet-joint Injection Clinical and Cost-effective Trial
Conditions: Low Back Pain
Intervention: Active Procedure, Sham Procedure
November 7, 2017
55664
NCT02608723
Completed
Shock Wave Therapy: Do the External Appearance of the Device Influence Clinical Outcomes?
Conditions: Plantar Fasciitis; Pain
Intervention: Standard Shock Waves Device, Austere Shock Waves Device, Sophisticated Shock Waves Device
November 17, 2015
55665
NCT00863616
Completed
High Frequency Chest Wall Oscillation in Chronic Obstructive Pulmonary Disease (COPD)
Conditions: Chronic Obstructive Pulmonary Disease
Intervention: HFCWO - SmartVest
March 17, 2009
55666
NCT02884193
Enrolling by invitation
Effectiveness of the Technique of "Quick Icing" (QI) on the Handgrip Strength Compared With the Use of Prolonged Cold and a Control
Conditions: Muscle Strength
Intervention: Brief Cooling, Prolonged Cold, Sham Ice Bag
June 6, 2019
55667
NCT02495298
Completed
Fascial Manipulation on the Treatment of Carpal Tunnel Syndrome
Conditions: Carpal Tunnel Syndrome
October 3, 2016
55668
NCT00448513
Completed
Effects of Tea Catechin Extracts on Oxidative Damage
Conditions: Healthy
July 14, 2013
55669
NCT02017418
Completed
The Effects of a Zeaxanthin Intervention on Visuomotor Function
Conditions: Behavior and Behavior Mechanisms
Intervention: Zeaxanthin, Combinatory Supplement
May 26, 2015
55670
NCT02043613
Completed
Context Effects in Exercise Therapy for Knee and/or Hip Pain
Conditions: Joint Pain; Knee Pain; Hip Pain; Osteoarthritis, Knee; Osteoarthritis, Hip
Intervention: Contextually Enhanced Physical Surroundings Of Exercise, Neuromuscular Exercise
March 26, 2015
55671
NCT04095455
Recruiting
The Effect Of Ultrasound-guided Modified Pectoral Nerves Block Versus Ketamine Plus Magnesium Infusion On Analgesic Profile In Breast Cancer Surgeries
Conditions: Postoperative Pain
Intervention: Pectoral Nerves Block Group, Ketamine Plus Magnesium Group, Control Group
September 17, 2019
55672
NCT01395108
Completed
Clinical Study on Oral Nemonoxacin Malate Capsules
Conditions: Healthy Volunteers
Intervention: Nemonoxacin
July 13, 2011
55673
NCT02239445
Completed
Intranasal Dexmedetomidine VS Oral Chloral Hydrate for Rescue Sedation During Magnetic Resonance Imaging
Conditions: Administration Related Reaction; Failed Moderate Sedation During Procedure; Chloral Hydrate Adverse Reaction
Intervention: Chloral Hydrate Group, Low Dose Dexmedetomidine Group, High Dose Dexmedetomidine Group
May 9, 2015
55674
NCT03551808
Recruiting
Prophylactic Effect of Ketorolac Tromethamine on the Cystoid Macular Edema After Phacoemulsification in Diabetic Patients
Conditions: Cystoid Macular Edema After Phacoemulsification
Intervention: Using Of Ketorolac Tromethamine Eye Drop
May 29, 2018
55675
NCT03233022
Completed
An Online Trial of Five Well-being Programs
Conditions: Well-being
Intervention: Happify
July 31, 2018
55676
NCT00637273
Completed
A Study to Compare the Glycemic Effects, Safety, and Tolerability of Exenatide Once Weekly to Those of Sitagliptin and Pioglitazone,in Subjects With Type 2 Diabetes Treated With Metformin (DURATION - 2)
Conditions: Type 2 Diabetes Mellitus
Intervention: Exenatide Once Weekly, Sitagliptin, Pioglitazone, Placebo Tablet, Placebo Once Weekly
March 19, 2015
55677
NCT01493908
Unknown status
The Effect of Marketing Variable on Effect of Active Drugs
Conditions: Pain
Intervention: High Price, Low Price, Low Price Participants Aware Paying Part, No Price, Free Of Charge
December 15, 2011
55678
NCT03076515
Terminated
Migraine Treatment With Nerivio Migra Neurostimulation Device
Conditions: Acute Migraine
Intervention: Nerivio Migra Neurostimulation, Sham Nerivio Migra
May 3, 2018
55679
NCT00852540
Completed
Retapamulin Versus Linezolid in the Treatment of SITL and Impetigo Due to MRSA
Conditions: Skin Infections, Bacterial
Intervention: Retpamulin Ointment, 1%, Linezolid
February 23, 2017
55680
NCT02317341
Terminated
Effect of Ketamine on Fatigue Following Cancer Therapy
Conditions: Cancer; Fatigue; Ketamine
Intervention: Ketamine, Placebo (saline), Ketamine, Midazolam, Midazolam(placebo)
March 19, 2019
55681
NCT02847143
Unknown status
Ocytocine and Cerebral Activation in Relation With Attachement
Conditions: Attachement Style
Intervention: Nasal Oxytocin Or Placebo, FMRI, Attachement Scale Interview (ASI), Psychometric Scales
July 21, 2017
55682
NCT00688194
Unknown status
Fulvestrant With or Without Lapatinib and/or Aromatase Inhibitor Therapy in Treating Postmenopausal Women With Metastatic Breast Cancer That Progressed After Previous Aromatase Inhibitor Therapy
Conditions: Breast Cancer
Intervention: Anastrozole, Exemestane, Fulvestrant, Lapatinib Ditosylate, Letrozole, Placebo
August 23, 2013
55683
NCT00753805
Completed
Dietetic Effects of Mare's Milk in Patients With Atopic Dermatitis
Conditions: Atopic Dermatitis
Intervention: Mare's Milk
September 15, 2008
55684
NCT03005184
Withdrawn
Mechanism(s) Underlying Cardiovascular Effects of ARB/NEP Inhibition - Aim 2
Conditions: Heart Failure NYHA Class I; Heart Failure NYHA Class II; Heart Failure NYHA Class III
Intervention: Valsartan 80 Mg Bid, Enalapril 10 Mg Bid, Sacubitril-Valsartan 200 Mg Bid, Icatibant, Placebo
January 9, 2018
55685
NCT01302990
Completed
Safety, Tolerability and Immunogenicity of a Plant-Made H1 VLP Influenza Vaccine in Adults
Conditions: Flu
Intervention: Dose Given At Day 0
August 15, 2013
55686
NCT01257191
Completed
A Study to Compare the Effects of Different Sized Particles on Cells in the Nose
Conditions: Hypersensitivity, Immediate; Atopic Hypersensitivity
Intervention: Carbon Black, Diesel Exhaust Particles, Fine Concentrated Ambient Particles, Ultrafine Concentrated Ambient Particles, Saline
January 9, 2017
55687
NCT01364818
Completed
Brain Connectivity in Neurodevelopmental Disorders in Response to Treatment
Conditions: Autism Spectrum Disorders; Psychosis; Fragile X Syndrome
April 14, 2016
55688
NCT01231828
Completed
Method of Assessment of Driving Ability in Patients Suffering From Wakefulness Pathologies.
Conditions: Cirrhosis
Intervention: L-carnitine, Lactulose
February 26, 2013
55689
NCT01070004
Completed
Effect of Countermeasures on Nocturnal Driving Performance
Conditions: Sleepiness
Intervention: Real Driving Situation, Driving Simulator
June 13, 2012
55690
NCT01573273
Completed
Oxytocin in Cocaine Dependence
Conditions: Cocaine Dependence
Intervention: Oxytocin, Saline
March 11, 2019
55691
NCT01078909
Completed
Dose Response Effects of Marine Omega-3 Fatty Acids on Inflammation
Conditions: Cardiovascular Disease; Inflammation
Intervention: Eicosapentaenoic Acid And Docosahexaenoic Acid (EPA + DHA)
September 29, 2017
55692
NCT01859962
Completed
Study of PPI-668, BI 207127 and Faldaprevir, With and Without Ribavirin, in the Treatment of Chronic Hepatitis C
Conditions: Chronic Hepatitis C
Intervention: PPI-668, BI 207127 Dose 1, BI 207127 Dose 2, Faldaprevir, Ribavirin, BI 207127 Placebo
November 24, 2015
55693
NCT01193920
Completed
Safety and Immunogenicity of a Group B Streptococcus Vaccine in Non Pregnant and Pregnant Women 18-40 Years of Age
Conditions: Streptococcal Infections
Intervention: Group B Streptococcus Trivalent Vaccine - 20/20/20 Μg, Saline Solution, Group B Streptococcus Trivalent Vaccine - 0.5/0.5/0.5 Μg, Group B Streptococcus Trivalent Vaccine - 2.5/2.5/2.5 Μg, Group B Streptococcus Trivalent Vaccine - 5/5/5 Μg, Saline Solution
August 18, 2014
55694
NCT01323621
Completed
Study Evaluating the 24-Hour Pulmonary Function Profile of Fluticasone Furoate (FF) /GW642444 (Vilanterol) (VI) Inhalation Powder 100/25mcg Once Daily Compared With Fluticasone Propionate/Salmeterol Inhalation Powder 250/50mcg Twice Daily in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
Conditions: Pulmonary Disease, Chronic Obstructive
Intervention: Fluticasone Furoate 100mcg/ GW642444 (vilanterol) 25mcg, Fluticasone Propionate 250mcg / Salmeterol 50mcg, Double-dummy Placebo, Salbutamol As Needed
January 18, 2018
55695
NCT01609153
Completed
Comparison of Antipsychotic Combination Treatment of Olanzapine and Amisulpride to Monotherapy
Conditions: Schizophrenia; Schizoaffective Disorder
Intervention: Olanzapine, Amisulpride, Olanzapine And Amisulpride
April 15, 2019
55696
NCT01106365
Completed
Repetitive Deep Transcranial Magnetic Stimulation in Multiple Sclerosis
Conditions: Multiple Sclerosis
Intervention: H-coil (Repetitive Deep Transcranial Magnetic Stimulation)
November 28, 2018
55697
NCT01369095
Completed
Efficacy and Safety of Fixed Doses of BMS 820836 in the Treatment of Patients With Treatment Resistant Major Depression
Conditions: Depression
Intervention: Duloxetine, Escitalopram, BMS-820836 Placebo, BMS-820836, BMS-820836, BMS-820836, BMS-820836
September 23, 2015
55698
NCT03515837
Recruiting
Study of Pemetrexed + Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Adults With Tyrosine Kinase Inhibitor- (TKI)-Resistant Epidermal Growth Factor Receptor- (EGFR)-Mutated Metastatic Non-squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-789/KEYNOTE-789)
Conditions: Non-small Cell Lung Cancer
Intervention: Pembrolizumab, Pemetrexed, Carboplatin, Cisplatin, Saline Solution
December 5, 2019
55699
NCT00771264
Completed
Study of Urgent PC Versus Sham Effectiveness in Treatment of Overactive Bladder Symptoms
Conditions: Overactive Bladder
Intervention: Urgent PC Neuromodulation System
April 13, 2012
55700
NCT02049970
Completed
Effect of the Addition of Dexmedetomidine to Bupivacaine During Supraclavicular Brachial Plexus Blockade
Conditions: Sequelae of Fracture of Forearm and Upper Arm
Intervention: Dexmedetomidine, Bupivacaine
November 7, 2014

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Last Updated

The last updated date is the most recent date when changes to a clinical trial were submitted to ClinicalTrials.gov. There is often a delay of a few days before the updated trial is available on the clinical trials website.

Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.

Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.

First Received

The first received date is the date when the clinical trial was first submitted to ClinicalTrials.gov. There is often a delay of a few days before the trial is available on the clinical trials website.

Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.

Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.

Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.

Safety Issue

If selected, restricts search results to those studies which have an outcome measure designated as a safety issue. Note that this is a poor estimate of the safety of a treatment or intervention, but it is all we have now.

Funded By

Studies are supported by one or more organizations called sponsors. Support includes contributions of facilities, expertise, and/or financial resources. All sponsors in the database have been assigned one of the following organization types:

National Institutes of Health (NIH)

Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.

Industry - the pharmaceutical companies

University/Organization - all others, including community-based organizations

Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.

Study Phase

Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions that study is seeking to answer:

In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.

In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.

In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.

In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.

These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.

Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.

Age Group

Studies may be designed for participants of particular ages:

Children (birth-17 yrs old)

Adults (18-65 yrs old)

Senior (66+ yrs old)

Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.

Gender

Searches can be restricted to studies which accept female or male participants.
Location Terms

If you are interested in a specific city (such as Los Angeles) or facility name (such as the Mayo Clinic), enter it as a location term. Not all studies include this level of detail, but if they do, this will find them.

Countries and States

Trials are often conducted at many locations around the world. Select up to three locations to find trials conducted in specific countries. Some countries (currently limited to the United States, Canada, and Australia), locations can be narrowed further by selecting a state.

Study IDs

Each trial is assigned one or more identification numbers by the institute, agency, or organization sponsoring the trial. In addition, clinical trials assigns a unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit. Use this box to search for a trial by NCT identifier or any other study identification numbers.

Examples:

NCT00001789
97-h-0197
ia0006
actg 076

Sponsor (Lead)

Use this box to specify the name of an institute, organization, or company that is conducting a trial.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.

A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.

When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Examples:

National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators

Use this box to specify institutes, organizations, or companies that are conducting or otherwise supporting a trial.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.

Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.

When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Examples:

National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb

Outcome Measures

Outcome measures are used to evaluate trial results. For example, an obesity treatment might be evaluated by a measure of weight loss after 6 months. Measures can also be used to quantify side effects, such as number of myocardial infarctions, number of patients with heart arrhythmia, number of suicides, etc.

Use this box to specify an outcome measure used to evaluate trial results.

Examples:

weight loss
heart failure
suicide

Interventions

Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied. Interventions can also include less intrusive possibilities such as surveys, education, and interviews.

Use this box to specify drugs, devices, procedures, or vaccines used in a trial.

Examples:

clofibrate
cyclosporine
vitamin e

Conditions

Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov, conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.

Use this box to specify the conditions being studied.

Examples:

lupus
heart attack
leukemia
risk factors for breast cancer

Study Type

There are three types of studies available in ClinicalTrials.gov:

Interventional:

Studies where individuals are assigned to receive specific interventions. Participants may receive diagnostic, therapeutic or other types of interventions. Assignment of the intervention may or may not be random. Individuals are tracked and biomedical and/or health outcomes are assessed.

Observational:

Studies without an intervention. Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals. Participants may receive diagnostic, therapeutic, or other interventions, but the investigator does not assign specific interventions to the participants of the study.

Expanded Access:

Records describing the procedure for obtaining an experimental drug or device for patients who are failing on currently available treatments for their condition and also are unable to participate in ongoing clinical trials. Expanded Access records are used to register all types of non-protocol access to experimental treatments, including protocol exception, single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.

Study Results

Searches can be restricted to studies with or without results.

The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.

Recruitment Status

Also known as Enrollment Status.

Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.

If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.

Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.

Full list of all possible recruitment status values:

Open recruitment status values:

Recruiting,
Not yet recruiting, or
Available for expanded access.

Closed recruitment status values:

Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.

Values are color coded (as shown) in the search results.

Search Terms

Use this box to specify general search terms found anywhere in the trial record.

Multiple terms can be separated by an AND (all uppercase).

Examples:

type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study


Help for Searching clinical trials

Help Topics:
Basic Search
Advanced Search
Refine Search
Search Expressions


Basic Search:

On the Basic Search page, enter a word or word(s) that you want to use to find studies. These may include diseases, interventions, and/or locations.

Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks

A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.


Advanced Search:

Many searches are a single term and can be performed with a few words in the search box. But, sometimes you need more control. Click on the Advanced Search tab (if starting a new search) or Refine Search tab (if modifying an existing search) to show additional search fields.

The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.

Search Terms:
Performs a general search in all sections of the study record, including title, description, conditions, interventions, locations, etc. Terms in this field are searched the same as Basic Search.

Recruitment:
Limits search results to studies that are open or closed. New volunteers may be able to participate in open studies, but not closed studies.

Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.

Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.

Values are color coded (as shown) in the search results.

Study Results:
Limits search results based on whether the study has results or not:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov. Only a few studies have results available.

Study Type:
Limits search results to any of the following study types:
Interventional,
Observational, or
Expanded Access

Conditions:
Performs a search on fields describing the diseases or conditions being studied.

Interventions:
Performs a search on fields listing the drugs or interventions being studied.

Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.

Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.

When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Sponsor (Lead):
Performs a search on the sponsor field of a study.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.

When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Study IDs:
Performs a search on fields listing ID numbers.

Country/State:
Trials are often conducted at many locations around the world. Select up to three locations to find trials conducted in specific countries. Some countries (currently limited to the United States, Canada, and Australia), locations can be narrowed further by selecting a state (e.g., United States, Alabama).

Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic). Not all studies include this level of detail, but if they do, this will find them.

Gender:
Limits search results to those studies that accept female or male participants.

Age Group:
Limits search results to those studies that include at least one of the specified age ranges. More than one age group can be selected.

Phase:
Limits search results to studies that are labeled with at least one of the specified phases. More than one Phase can be selected.

Funded By:
Limits search results to studies that have at least one sponsor of the specified types. More than one sponsor type can be selected.

Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.

First Received:
Limits search results to studies that were received by clinical trials within a specified date range. The "From" or "To" field can be left blank.

Last Updated:
Limits search results to studies that were modified within a specified date range. The "From" or "To" field can be left blank.


Refine Search:

Searches display a list of studies found (List Results tab). If you are not content with the search results, click on the Refine Search tab at the top of the list to modify your search.

Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.

For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California

When you are done making changes, click Search to display the new results.


Search Expressions:

Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California

Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack

Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS

Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )

Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.

To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.

Conditions

Alphabetic (A-Z)
By Category

Rare Diseases

Alphabetic (A-Z)

Drug
Interventions

Alphabetic (A-Z)
By Category

Dietary
Supplements

Alphabetic (A-Z)
By Category

Sponsor/
Collaborators

Alphabetic (A-Z)
By Category

Locations

Alphabetic (A-Z)
By Category