ICH GCP | Clinical Trials Registry

Clinical Trials: SEARCH[STUDY] TILT[STUDY:STUDY-FIRST-POSTED] ( Placebo [STUDY:TREATMENT] )



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#
NCTID/Status
Study
Last Changed
55651
NCT03002259
Recruiting
Dexamethasone for Cardiac Surgery-II Trial
Conditions: Inflammatory Response
Intervention: Dexamethasone
March 18, 2019
55652
NCT02330276
Completed
Early Phase Pre-Clinical and Initial Clinical Research on Epicatechin
Conditions: Pre-diabetes
Intervention: (+)-Epicatechin
March 3, 2017
55653
NCT02731950
Completed
Presternal Bupivacaine Plus Magnesium Sulfate Infusion After Cardiac Surgery
Conditions: Pain; Postoperative Pain
Intervention: Magnesium Sulfate And Bupivacaine 0.125%
March 31, 2017
55654
NCT02713191
Completed
Dexmedetomidine vs. Midazolam Sedation for Endobronchial Ultrasound
Conditions: Conscious Sedation During Procedure; Endobronchial Ultrasound
Intervention: Dexmedetomidine, Midazolam Bolus, Saline Placebo, Rescue Midazolam, Fentanyl
February 16, 2017
55655
NCT03306043
Recruiting
A Multi-center, Open-label Extension, Safety Study of Mepolizumab in Subjects With Hypereosinophilic Syndrome (HES) From Study 200622
Conditions: Hypereosinophilic Syndrome
Intervention: Mepolizumab
August 16, 2019
55656
NCT01107938
Unknown status
Ilaprazole for the Treatment of Gastroesophageal Reflux Disease (GERD) in Chinese Patients
Conditions: Gastroesophageal Reflux Disease
Intervention: 10 Mg Ilaprazole, 15 Mg Ilaprazole, 40 Mg Esomeprazole
April 20, 2010
55657
NCT00265239
Completed
Pilot Study of Edaravone to Treat Acute Myocardial Infarction
Conditions: Myocardial Infarction; Reperfusion Injury
Intervention: Edaravone
September 12, 2014
55658
NCT00128193
Completed
Leprosy Skin Test Antigens Trial
Conditions: Leprosy
Intervention: Tuberculin, Purified Protein Derivative, MLSA-LAM, MLCwA, Tuberculin, Purified Protein Derivative, Placebo
December 4, 2014
55659
NCT03036644
Recruiting
Comparison of Electronic Cigarettes and Tobacco Cigarettes on Cardiovascular Function and Oxidative Stress
Conditions: Cardiovascular Risk Factor
Intervention: E-cigarette (PG+VG Without Nicotine; Low Temperature), E-cigarette (PG+VG With Nicotine; Low Temperature), E-cigarette (PG+VG Without Nicotine; High Temperature), E-cigarette (PG+VG With Nicotine; High Temperature), Tobacco Cigarette
October 10, 2018
55660
NCT02901275
Recruiting
Enhancing Medication-based Analgesia in Humans
Conditions: Pain
Intervention: Within-subject Test Of Blinded Study Medications
December 10, 2018
55661
NCT01015482
Unknown status
The Effect of High-dose Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers (HighDose RemiSun)
Conditions: Hyperalgesia
Intervention: Remifentanil, Midazolam
November 17, 2009
55662
NCT02446262
Recruiting
Neural and Psychological Mechanisms of Pain Perception
Conditions: Affective Neuroscience; Pain; Visual Analogue Pain Scale; Placebo; Functional Magnetic Resonance Imaging (fMRI)
August 7, 2019
55663
NCT03438864
Completed
Acute Effects of Interferential Current on Edema, Pain and Muscle Strength in Patients With Distal Radius Fracture
Conditions: Radius Fractures; Edema; Pain
Intervention: Electrotherapy, Interferential Current, Control
February 22, 2018
55664
NCT00262262
Completed
The Effect of Levetiracetam on the Postmastectomy Pain Syndrome
Conditions: Postoperative Pain
Intervention: Levetiracetam (drug)
November 21, 2007
55665
NCT02033707
Completed
Effects of Hallucinogens and Other Drugs on Mood and Performance
Conditions: Healthy
Intervention: Hallucinogens And Psychoactive Substances
May 15, 2019
55666
NCT01594320
Completed
A/H5N1 Virus-Like Particle Antigen Dose Ranging Study With Adjuvant 1
Conditions: Influenza (Pandemic)
Intervention: Monovalent Avian Influenza VLP (H5N1), Monovalent Avian Influenza VLP (H5N1), Monovalent Avian Influenza VLP (H5N1); Adjuvant, Monovalent Avian Influenza VLP (H5N1); Adjuvant, Monovalent Avian Influenza VLP (H5N1); Adjuvant, Saline Placebo
February 5, 2014
55667
NCT01596725
Completed
A/H5N1 Virus-Like Particle Antigen Dose Ranging Study With Adjuvant 2
Conditions: Influenza (Pandemic)
Intervention: Monovalent Avian Influenza VLP (H5N1), Monovalent Avian Influenza VLP (H5N1), Monovalent Avian Influenza VLP (H5N1); Adjuvant, Monovalent Avian Influenza VLP (H5N1); Adjuvant, Monovalent Avian Influenza VLP (H5N1); Adjuvant, Saline Placebo
February 5, 2014
55668
NCT01116531
Withdrawn
Efficacy, Safety, Tolerability and Pharmacokinetics of Concomitant Administration of Tramadol With Duloxetine or Pregabalin
Conditions: Diabetic Polyneuropathy; Postherpetic Neuralgia
Intervention: Tramadol, Duloxetine, Pregabalin
May 30, 2013
55669
NCT00811837
Unknown status
The Effect of Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers
Conditions: Hyperalgesia
Intervention: Midazolam, Remifentanil
November 17, 2009
55670
NCT01265888
Completed
Study in Subjects With PAH and PH Secondary to IPF Using Inhaled GeNOsyl.
Conditions: Pulmonary Arterial Hypertension; Idiopathic Pulmonary Fibrosis
Intervention: Inhaled Nitric Oxide, Inhaled Nitric Oxide, Inhaled Nitric Oxide
September 16, 2016
55671
NCT03880240
Not yet recruiting
Gamma Induction for Alzheimer's Disease
Conditions: Alzheimer Disease
Intervention: Transcranial Alternating Current Stimulation (tACS), Sham Transcranial Alternating Current Stimulation
April 1, 2019
55672
NCT02595489
Recruiting
A Pilot Study of Vitamin D in Boys With X-linked Adrenoleukodystrophy
Conditions: X-linked Adrenoleukodystrophy
Intervention: Vitamin D3
June 4, 2019
55673
NCT00856401
Active, not recruiting
ADD-ON Study to Existing Hypoparathyroidism Studies
Conditions: Hypoparathyroidism
Intervention: PTH1-84 In Parent Study
February 27, 2018
55674
NCT02942888
Active, not recruiting
The Effects of Nicotinamide Adenine Dinucleotide (NAD) on Brain Function and Cognition
Conditions: Mild Cognitive Impairment; NAD
Intervention: Nicotinamide Riboside, Sugar Pill
July 22, 2019
55675
NCT00726882
Completed
A Follow-up Assessment of Resistance to ABT-333 in Hepatitis C Virus (HCV)-Infected Subjects Who Have Received ABT-333 in ABT-333 Studies
Conditions: HCV Infection
Intervention: Blood Sample Collection Only, ABT-333
December 29, 2014
55676
NCT01377961
Withdrawn
Effect of Lycopene and Isoflavones on Glucose Metabolism
Conditions: Metabolic Syndrome; Diabetes Mellitus, Non-Insulin-Dependent
Intervention: Randomized Pills Either Containing Combination Of Lycopene And Isoflavones (dietary Supplements) Or Placebo To Be Taken For 12 Weeks, Screening, OGTT, Anthropometrics And Blood Pressure, Screening, Blood Drawing
June 24, 2015
55677
NCT01460628
Completed
Effect of Nuvigil on Fatigue
Conditions: Menopause
Intervention: Armodafinil
January 25, 2017
55678
NCT03076463
Completed
Grape Pomace Polyphenols and Cardiometabolic Risk
Conditions: Subjects at Cardiometabolic Risk
Intervention: GRAPOM
April 4, 2018
55679
NCT02035241
Completed
Effect of Herbs and Spices on Metabolic Regulation and Appetite in Healthy Subjects
Conditions: Healthy
Intervention: Spices 1, Spices 2, Spices 3, Herbs 1, Herbs 2, Control Drink
August 23, 2018
55680
NCT01509469
Completed
The Effect of Different Macronutrients on Ileal Brake Activation
Conditions: Obesity; Overweight
Intervention: Casein, Casein, Sucrose, Sucrose, Saline, Safflower Oil
January 28, 2014
55681
NCT01776619
Completed
Safety and Tolerability Study of Multiple Doses of PF-06305591
Conditions: Healthy
Intervention: PF-06305591, Placebo, PF-06305591, Placebo, PF-06305591, Placebo, PF-06305591, PF-06305591
December 2, 2013
55682
NCT03875326
Recruiting
Stimulation to Undermine Dementia
Conditions: Mild Cognitive Impairment
Intervention: 1 MA HD-tDCS, 2 MA HD-tDCS, 3 MA HD-tDCS, Sham
March 13, 2019
55683
NCT00800267
Completed
A Study of Glaucoma or Ocular Hypertension in Patients Within the United States
Conditions: Ocular Hypertension; Glaucoma
Intervention: Latanoprost 0.005%, Fixed Combination Latanoprost-timolol, Timolol 0.5%
March 5, 2009
55684
NCT01694199
Terminated
Pulsed Radiofrequency Energy to Treat Post-Bunionectomy Pain
Conditions: Post-operative Pain
Intervention: Pulsed Radiofrequency Energy (PRFE), No Pulsed Radiofrequency Energy (PRFE)
March 21, 2017
55685
NCT00567866
Terminated
Methamphetamine-Quetiapine Interactions in Humans
Conditions: Methamphetamine Dependence
Intervention: Quetiapine
July 12, 2010
55686
NCT03409211
Recruiting
Patterns After Administration of MCFAs in Psoriasis and Psoriatic Arthritis
Conditions: Psoriasis; Psoriatic Arthritis
Intervention: PEVCO, Dietary Supplement Capsules Without Coconut Oil
December 20, 2018
55687
NCT01353911
Completed
Grazoprevir (MK-5172) Administered With Peginterferon and Ribavirin in Treatment-Naïve Participants With Chronic Hepatitis C (MK-5172-003)
Conditions: Hepatitis C, Chronic
Intervention: Grazoprevir, Boceprevir, Placebo For Grazoprevir, Placebo For Boceprevir, Peg-interferon Alfa-2b, Ribavirin
August 16, 2018
55688
NCT01591967
Completed
Measure the Effects of Specific Thoracic Chiropractic Adjustments on Blood Pressure and Pulse Rate
Conditions: Hypertension
Intervention: Activator IV Adjusting Instrument
May 2, 2012
55689
NCT01796912
Completed
Lipoprotein Apheresis in Refractory Angina Study
Conditions: Refractory Angina; Raised Lipoprotein(a)>50mg/dL or >500mg/L
Intervention: Lipoprotein Apheresis, Sham Apheresis
February 15, 2016
55690
NCT00339768
Completed
A Randomized Multi-Intervention Trial to Inhibit Precancerous Gastric Lesions in Lingu, Shandong Province
Conditions: Precancerous Gastric Lesions
Intervention: Amoxicillin/omeprazole
August 16, 2019
55691
NCT00082511
Completed
GL701 (Prestara™) in Women With Systemic Lupus Erythematosus Receiving Treatment With Glucocorticoids
Conditions: Systemic Lupus Erythematosus
Intervention: Prasterone (GL701)
January 10, 2008
55692
NCT03998514
Recruiting
A Phase 1a/1b Study of CB4211 in Healthy Non-obese Subjects and Subjects With Nonalcoholic Fatty Liver Disease
Conditions: Nonalcoholic Fatty Liver Disease
Intervention: CB4211 Dose 1, CB4211 Dose 2, CB4211 Dose 3, CB4211 Dose 4, CB4211 Dose 5, CB4211 Dose 6, CB4211 Dose TBD, Placebo
June 25, 2019
55693
NCT00763061
Completed
Travatan Versus Timoptic in Treating Open-angle Glaucoma or Ocular Hypertension
Conditions: Glaucoma
Intervention: Travoprost 0.004% Ophthalmic Solution (Travatan), Timolol 0.5% Ophthalmic Solution (Timoptic)
February 23, 2010
55694
NCT02540382
Completed
Comparison of Covered and Bare Stent in TIPS
Conditions: Cirrhosis
Intervention: Covered Stent, Bare Stent
September 1, 2015
55695
NCT00134784
Completed
Long-Term Dopamine Transporter Imaging and Clinical Assessment of Parkinson's Disease Progression
Conditions: Parkinson Disease
Intervention: [123I]B-CIT SPECT Imaging
July 15, 2014
55696
NCT02537249
Completed
Effects of Dexmedetomidine on Quality of Recovery and Analgesia After Video-assisted Thoracoscopic Surgery
Conditions: Lung Cancer; Video-assisted Thoracoscopic Surgery
Intervention: Dexmedetomidine, Normal Saline
November 9, 2015
55697
NCT03095703
Completed
Sirolimus and Familial Adenomatous Polyposis (FAP)
Conditions: Adenomatous Polyposis Coli
Intervention: Sirolimus
January 25, 2019
55698
NCT01837303
Completed
chemQbiosciences:Manual Liquid Based Cytology
Conditions: Cervical Dysplasia; Cervical Cancer
Intervention: Pap Smear
December 3, 2013
55699
NCT02422940
Terminated
Study to Evaluate the Long-Term Safety, Tolerability and Efficacy of Dalfampridine.
Conditions: Post-ischemic Stroke
Intervention: Dalfampridine-ER 7.5 Mg, Dalfampridine-ER 10 Mg
January 17, 2019
55700
NCT02951897
Recruiting
Application of Detecting Circulating Tumor Cells in the Accurate Treatment of Early Stage Lung Adenocarcinoma
Conditions: Lung Adenocarcinoma, Stage I; Diagnoses Diseases; Circulating Tumor Cells; Treatment
Intervention: Lobectomy, Segmentecomy, Chemotherapy（pemetrexed+CISPLATIN）, Lymphadenectomy, CanPatrolTM To Detect CTCs
October 31, 2016

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Last Updated

The last updated date is the most recent date when changes to a clinical trial were submitted to ClinicalTrials.gov. There is often a delay of a few days before the updated trial is available on the clinical trials website.

Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.

Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.

First Received

The first received date is the date when the clinical trial was first submitted to ClinicalTrials.gov. There is often a delay of a few days before the trial is available on the clinical trials website.

Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.

Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.

Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.

Safety Issue

If selected, restricts search results to those studies which have an outcome measure designated as a safety issue. Note that this is a poor estimate of the safety of a treatment or intervention, but it is all we have now.

Funded By

Studies are supported by one or more organizations called sponsors. Support includes contributions of facilities, expertise, and/or financial resources. All sponsors in the database have been assigned one of the following organization types:

National Institutes of Health (NIH)

Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.

Industry - the pharmaceutical companies

University/Organization - all others, including community-based organizations

Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.

Study Phase

Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions that study is seeking to answer:

In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.

In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.

In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.

In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.

These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.

Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.

Age Group

Studies may be designed for participants of particular ages:

Children (birth-17 yrs old)

Adults (18-65 yrs old)

Senior (66+ yrs old)

Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.

Gender

Searches can be restricted to studies which accept female or male participants.
Location Terms

If you are interested in a specific city (such as Los Angeles) or facility name (such as the Mayo Clinic), enter it as a location term. Not all studies include this level of detail, but if they do, this will find them.

Countries and States

Trials are often conducted at many locations around the world. Select up to three locations to find trials conducted in specific countries. Some countries (currently limited to the United States, Canada, and Australia), locations can be narrowed further by selecting a state.

Study IDs

Each trial is assigned one or more identification numbers by the institute, agency, or organization sponsoring the trial. In addition, clinical trials assigns a unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit. Use this box to search for a trial by NCT identifier or any other study identification numbers.

Examples:

NCT00001789
97-h-0197
ia0006
actg 076

Sponsor (Lead)

Use this box to specify the name of an institute, organization, or company that is conducting a trial.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.

A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.

When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Examples:

National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators

Use this box to specify institutes, organizations, or companies that are conducting or otherwise supporting a trial.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.

Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.

When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Examples:

National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb

Outcome Measures

Outcome measures are used to evaluate trial results. For example, an obesity treatment might be evaluated by a measure of weight loss after 6 months. Measures can also be used to quantify side effects, such as number of myocardial infarctions, number of patients with heart arrhythmia, number of suicides, etc.

Use this box to specify an outcome measure used to evaluate trial results.

Examples:

weight loss
heart failure
suicide

Interventions

Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied. Interventions can also include less intrusive possibilities such as surveys, education, and interviews.

Use this box to specify drugs, devices, procedures, or vaccines used in a trial.

Examples:

clofibrate
cyclosporine
vitamin e

Conditions

Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov, conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.

Use this box to specify the conditions being studied.

Examples:

lupus
heart attack
leukemia
risk factors for breast cancer

Study Type

There are three types of studies available in ClinicalTrials.gov:

Interventional:

Studies where individuals are assigned to receive specific interventions. Participants may receive diagnostic, therapeutic or other types of interventions. Assignment of the intervention may or may not be random. Individuals are tracked and biomedical and/or health outcomes are assessed.

Observational:

Studies without an intervention. Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals. Participants may receive diagnostic, therapeutic, or other interventions, but the investigator does not assign specific interventions to the participants of the study.

Expanded Access:

Records describing the procedure for obtaining an experimental drug or device for patients who are failing on currently available treatments for their condition and also are unable to participate in ongoing clinical trials. Expanded Access records are used to register all types of non-protocol access to experimental treatments, including protocol exception, single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.

Study Results

Searches can be restricted to studies with or without results.

The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.

Recruitment Status

Also known as Enrollment Status.

Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.

If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.

Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.

Full list of all possible recruitment status values:

Open recruitment status values:

Recruiting,
Not yet recruiting, or
Available for expanded access.

Closed recruitment status values:

Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.

Values are color coded (as shown) in the search results.

Search Terms

Use this box to specify general search terms found anywhere in the trial record.

Multiple terms can be separated by an AND (all uppercase).

Examples:

type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study


Help for Searching clinical trials

Help Topics:
Basic Search
Advanced Search
Refine Search
Search Expressions


Basic Search:

On the Basic Search page, enter a word or word(s) that you want to use to find studies. These may include diseases, interventions, and/or locations.

Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks

A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.


Advanced Search:

Many searches are a single term and can be performed with a few words in the search box. But, sometimes you need more control. Click on the Advanced Search tab (if starting a new search) or Refine Search tab (if modifying an existing search) to show additional search fields.

The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.

Search Terms:
Performs a general search in all sections of the study record, including title, description, conditions, interventions, locations, etc. Terms in this field are searched the same as Basic Search.

Recruitment:
Limits search results to studies that are open or closed. New volunteers may be able to participate in open studies, but not closed studies.

Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.

Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.

Values are color coded (as shown) in the search results.

Study Results:
Limits search results based on whether the study has results or not:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov. Only a few studies have results available.

Study Type:
Limits search results to any of the following study types:
Interventional,
Observational, or
Expanded Access

Conditions:
Performs a search on fields describing the diseases or conditions being studied.

Interventions:
Performs a search on fields listing the drugs or interventions being studied.

Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.

Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.

When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Sponsor (Lead):
Performs a search on the sponsor field of a study.

It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.

When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.

Study IDs:
Performs a search on fields listing ID numbers.

Country/State:
Trials are often conducted at many locations around the world. Select up to three locations to find trials conducted in specific countries. Some countries (currently limited to the United States, Canada, and Australia), locations can be narrowed further by selecting a state (e.g., United States, Alabama).

Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic). Not all studies include this level of detail, but if they do, this will find them.

Gender:
Limits search results to those studies that accept female or male participants.

Age Group:
Limits search results to those studies that include at least one of the specified age ranges. More than one age group can be selected.

Phase:
Limits search results to studies that are labeled with at least one of the specified phases. More than one Phase can be selected.

Funded By:
Limits search results to studies that have at least one sponsor of the specified types. More than one sponsor type can be selected.

Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.

First Received:
Limits search results to studies that were received by clinical trials within a specified date range. The "From" or "To" field can be left blank.

Last Updated:
Limits search results to studies that were modified within a specified date range. The "From" or "To" field can be left blank.


Refine Search:

Searches display a list of studies found (List Results tab). If you are not content with the search results, click on the Refine Search tab at the top of the list to modify your search.

Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.

For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California

When you are done making changes, click Search to display the new results.


Search Expressions:

Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California

Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack

Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS

Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )

Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.

To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.

Conditions

Alphabetic (A-Z)
By Category

Rare Diseases

Alphabetic (A-Z)

Drug
Interventions

Alphabetic (A-Z)
By Category

Dietary
Supplements

Alphabetic (A-Z)
By Category

Sponsor/
Collaborators

Alphabetic (A-Z)
By Category

Locations

Alphabetic (A-Z)
By Category