Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[InterventionSearch] Placebo
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Terminated
Conditions: Depressive Disorder
Intervention: Right Temporal Low Frequency (1 Hz) RTMS, Sham-rTMS
Completed
Conditions: Colorectal Cancer (CRC)
Intervention: Irinotecan, 5-Fluorouracil (bolus), 5-Fluorouracil (infusional), Leucovorin Calcium, CT-322, Bevacizumab, Bevacizumab Placebo (saline Solution)
Completed
Conditions: Pulmonary Disease, Chronic Obstructive
Intervention: Tiotropium 18 Mcg, Tiotropium 1.25 Mcg (2 Actuations/day), Tiotropium 2.5 Mcg (2 Actuations/day)
Completed
Conditions: Growth Hormone Disorder; Adult Growth Hormone Deficiency
Intervention: NNC126-0083, NNC126-0083, NNC126-0083, NNC126-0083, Placebo, Placebo, Placebo, Placebo
Terminated
Conditions: Food Allergies
Intervention: Food Drops: Food Allergens (peptides)
Not yet recruiting
Conditions: Healthy First Degree Relatives of Crohn's Disease Patients
Intervention: Prebiotics, Low N-6 PUFA Diet, Maltodextrin, Control Diet
Recruiting
Conditions: Acanthamoeba Keratitis
Intervention: Chlorhexidine, Povidone-Iodine, Prednisolone Sodium Phosphate, Hydroxypropyl Methylcellulose, Prednisolone Sodium Phosphate, Hydroxypropyl Methylcellulose
Recruiting
Conditions: Chronic Kidney Diseases; Heart Attack; Stroke, Ischemic
Intervention: Ticagrelor 90mg, Clopidogrel 75mg, Aspirin 81 Mg
Not yet recruiting
Conditions: Children; Chemotherapy-induced Nausea and Vomiting; Malignant Tumor
Intervention: Laser Therapy
Completed
Conditions: Venous Thrombosis
Intervention: Enoxaparin, Warfarin, Placebo For Apixaban, Placebo For Enoxaparin, Placebo For Warfarin, Apixaban
Completed
Conditions: Sleep; Alertness; Fatigue
Intervention: Bright Light Box
Recruiting
Conditions: Healing Surgical Wounds; Pain Measurement
Intervention: J. Morita AdvErl Evo Er:YAG Laser, Control
Completed
Conditions: Low Back Pain
Intervention: Active Procedure, Sham Procedure
Completed
Conditions: Plantar Fasciitis; Pain
Intervention: Standard Shock Waves Device, Austere Shock Waves Device, Sophisticated Shock Waves Device
Completed
Conditions: Chronic Obstructive Pulmonary Disease
Intervention: HFCWO - SmartVest
Enrolling by invitation
Conditions: Muscle Strength
Intervention: Brief Cooling, Prolonged Cold, Sham Ice Bag
Completed
Conditions: Carpal Tunnel Syndrome
Completed
Conditions: Healthy
Completed
Conditions: Behavior and Behavior Mechanisms
Intervention: Zeaxanthin, Combinatory Supplement
Completed
Conditions: Joint Pain; Knee Pain; Hip Pain; Osteoarthritis, Knee; Osteoarthritis, Hip
Intervention: Contextually Enhanced Physical Surroundings Of Exercise, Neuromuscular Exercise
Recruiting
Conditions: Postoperative Pain
Intervention: Pectoral Nerves Block Group, Ketamine Plus Magnesium Group, Control Group
Completed
Conditions: Healthy Volunteers
Intervention: Nemonoxacin
Completed
Conditions: Administration Related Reaction; Failed Moderate Sedation During Procedure; Chloral Hydrate Adverse Reaction
Intervention: Chloral Hydrate Group, Low Dose Dexmedetomidine Group, High Dose Dexmedetomidine Group
Recruiting
Conditions: Cystoid Macular Edema After Phacoemulsification
Intervention: Using Of Ketorolac Tromethamine Eye Drop
Completed
Completed
Conditions: Type 2 Diabetes Mellitus
Intervention: Exenatide Once Weekly, Sitagliptin, Pioglitazone, Placebo Tablet, Placebo Once Weekly
Unknown status
Conditions: Pain
Intervention: High Price, Low Price, Low Price Participants Aware Paying Part, No Price, Free Of Charge
Terminated
Conditions: Acute Migraine
Intervention: Nerivio Migra Neurostimulation, Sham Nerivio Migra
Completed
Conditions: Skin Infections, Bacterial
Intervention: Retpamulin Ointment, 1%, Linezolid
Terminated
Conditions: Cancer; Fatigue; Ketamine
Intervention: Ketamine, Placebo (saline), Ketamine, Midazolam, Midazolam(placebo)
Unknown status
Conditions: Attachement Style
Intervention: Nasal Oxytocin Or Placebo, FMRI, Attachement Scale Interview (ASI), Psychometric Scales
Unknown status
Conditions: Breast Cancer
Intervention: Anastrozole, Exemestane, Fulvestrant, Lapatinib Ditosylate, Letrozole, Placebo
Completed
Conditions: Atopic Dermatitis
Intervention: Mare's Milk
Withdrawn
Conditions: Heart Failure NYHA Class I; Heart Failure NYHA Class II; Heart Failure NYHA Class III
Intervention: Valsartan 80 Mg Bid, Enalapril 10 Mg Bid, Sacubitril-Valsartan 200 Mg Bid, Icatibant, Placebo
Completed
Conditions: Flu
Intervention: Dose Given At Day 0
Completed
Conditions: Hypersensitivity, Immediate; Atopic Hypersensitivity
Intervention: Carbon Black, Diesel Exhaust Particles, Fine Concentrated Ambient Particles, Ultrafine Concentrated Ambient Particles, Saline
Completed
Conditions: Autism Spectrum Disorders; Psychosis; Fragile X Syndrome
Completed
Conditions: Cirrhosis
Intervention: L-carnitine, Lactulose
Completed
Conditions: Sleepiness
Intervention: Real Driving Situation, Driving Simulator
Completed
Completed
Conditions: Cardiovascular Disease; Inflammation
Intervention: Eicosapentaenoic Acid And Docosahexaenoic Acid (EPA + DHA)
Completed
Conditions: Chronic Hepatitis C
Intervention: PPI-668, BI 207127 Dose 1, BI 207127 Dose 2, Faldaprevir, Ribavirin, BI 207127 Placebo
Completed
Conditions: Streptococcal Infections
Intervention: Group B Streptococcus Trivalent Vaccine - 20/20/20 Μg, Saline Solution, Group B Streptococcus Trivalent Vaccine - 0.5/0.5/0.5 Μg, Group B Streptococcus Trivalent Vaccine - 2.5/2.5/2.5 Μg, Group B Streptococcus Trivalent Vaccine - 5/5/5 Μg, Saline Solution
Completed
Conditions: Pulmonary Disease, Chronic Obstructive
Intervention: Fluticasone Furoate 100mcg/ GW642444 (vilanterol) 25mcg, Fluticasone Propionate 250mcg / Salmeterol 50mcg, Double-dummy Placebo, Salbutamol As Needed
Completed
Conditions: Schizophrenia; Schizoaffective Disorder
Intervention: Olanzapine, Amisulpride, Olanzapine And Amisulpride
Completed
Conditions: Multiple Sclerosis
Intervention: H-coil (Repetitive Deep Transcranial Magnetic Stimulation)
Completed
Conditions: Depression
Intervention: Duloxetine, Escitalopram, BMS-820836 Placebo, BMS-820836, BMS-820836, BMS-820836, BMS-820836
Recruiting
Conditions: Non-small Cell Lung Cancer
Intervention: Pembrolizumab, Pemetrexed, Carboplatin, Cisplatin, Saline Solution
Completed
Conditions: Overactive Bladder
Intervention: Urgent PC Neuromodulation System
Completed
Conditions: Sequelae of Fracture of Forearm and Upper Arm
Intervention: Dexmedetomidine, Bupivacaine
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Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
University/Organization - all others, including community-based organizations
Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Children (birth-17 yrs old)
Adults (18-65 yrs old)
Senior (66+ yrs old)
Click the check box to the left of each age group that you wish to include in your search. You can select more than one age group. If you do not select a any group, all groups will be included.
Examples:
97-h-0197
ia0006
actg 076
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
There are three types of studies available in ClinicalTrials.gov:
Observational:
Expanded Access:
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help Topics:
Basic Search:
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Open recruitment status values:
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Studies With Results, or
Studies Without Results
Observational, or
Expanded Access
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
Refine Search:
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
For example:
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.