Clinical Trials on Abnormal Renal Function

Total 14890 results

University of Calgary
University of Alberta

Completed

ENCOMPASS: Expansion Study A, RCT (ENCOMPASS)

Hypertension | Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Ischemic Heart Disease | Congestive Heart Failure

Canada
Reata, a wholly owned subsidiary of Biogen

Completed

A Phase 2 Trial of the Safety and Efficacy of Bardoxolone Methyl in Patients With Rare Chronic Kidney Diseases - PHOENIX (PHOENIX)

Focal Segmental Glomerulosclerosis | IgA Nephropathy | Autosomal Dominant Polycystic Kidney | CKD Associated With Type 1 Diabetes

United States
Tempest Therapeutics

Completed

TPST-1120 as Monotherapy and in Combination With Nivolumab in Subjects With Advanced Cancers

Sarcoma | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | Pancreatic Cancer | Squamous Cell Carcinoma of Head and Neck | Cholangiocarcinoma | Non-small Cell Lung Cancer | Urothelial Carcinoma | GastroEsophageal Cancer | Triple-Negative Breast Cancer | Metastatic Castration Resistant Prostate...

United States
CENTOGENE GmbH Rostock

Withdrawn

Biomarker for Patients With Fabry Disease (BioFabry) (BioFabry)

Chronic Kidney Disease | Hearing Loss | Angiokeratomas | Ocular Abnormalities

Sri Lanka, India, Germany
Synthekine

Recruiting

Phase 1a/1b Study of STK-012 Monotherapy and in Combination With Pembrolizumab in Patients With Solid Tumors

Renal Cell Carcinoma | Cervical Cancer | Gastric Cancer | Non Small Cell Lung Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Microsatellite Instability High | Malignant Melanoma | GastroEsophageal Cancer | Mismatch Repair Deficiency

United States
University of Calgary

Completed

ENCOMPASS: Expansion Study B, RCT (ENCOMPASS)

Hypertension | Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Ischemic Heart Disease | Congestive Heart Failure

Canada
Wen-Shiou Pan

Completed

Explore the Sharing Model Intervene to Improve the Knowledge, Attitudes, Service Intentions and Service Start-up Effects of the Eight Major Non-cancer Disease End-stage Caregivers on Well-being and Palliative Care

Heart Failure | Stroke | Pulmonary Disease, Chronic Obstructive | Kidney Failure, Chronic | Alzheimer Disease, Late Onset | Kidney Failure, Acute | Cystic Fibrosis Pulmonary Exacerbation | Chronic Liver Disease and Cirrhosis

Taiwan
Universitaire Ziekenhuizen KU Leuven
Norwegian Institute of Public Health; KU Leuven; University Ghent; Sciensano

Completed

Evidence-based Laboratory Test Order Sets in Primary Care

Liver Diseases | Cardiovascular Diseases | Sexually Transmitted Diseases | Hypertension | Obesity | Diabetes Mellitus | Fatigue | Chronic Kidney Diseases | Thyroid Diseases | Rheumatoid Arthritis | Diarrhea | Anemia | Acute Coronary Syndrome | Gout | Lung Embolism | Medication Monitoring | General Check-up

Belgium
Incyte Biosciences International Sàrl

Completed

A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignancies

Cervical Cancer | Hepatocellular Carcinoma | Esophageal Cancer | Ovarian Cancer | Mesothelioma | Non-small Cell Lung Cancer (NSCLC) | Urothelial Carcinoma | Merkel Cell Carcinoma | Diffuse Large B-cell Lymphoma | Triple-negative Breast Cancer | Renal Cell Carcinoma (RCC) | Small Cell Lung Cancer (SCLC) | Squamous... and other conditions

United States
University of Calgary
University of Alberta

Completed

ENCOMPASS: Expansion Study C

Hypertension | Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Ischemic Heart Disease | Congestive Heart Failure

Canada
University of Calgary
Alberta Innovates Health Solutions; Canadian Diabetes Association

Completed

Enhancing Community Health Through Patient Navigation, Advocacy and Social Support (ENCOMPASS)

Hypertension | Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Ischemic Heart Disease | Congestive Heart Failure

Canada
Rigshospitalet, Denmark
University College, London

Enrolling by invitation

EuroSIDA - Clinical and Virological Outcome of European Patients Infected With HIV (EuroSIDA)

End Stage Liver Disease | Cardiovascular Diseases | Fractures, Bone | Diabetes Mellitus | Renal Insufficiency | Hepatitis B | Hepatitis C | Kidney Failure, Chronic | Proteinuria | HIV | Coinfection | Acidosis, Lactic | AIDS

Spain, Switzerland, Germany, United Kingdom, Austria, Sweden, Finland, Israel, Denmark, France, Italy, Iceland, Belgium, Slovakia, Norway, Lithuania, Portugal, Poland, Croatia, Czechia, Greece, Hungary, Luxembourg, Argentina, Belarus, Bosnia... and more
Celldex Therapeutics

Completed

A Study of the PD-L1xCD27 Bispecific Antibody CDX-527 in Patients With Advanced Malignancies

Renal Cell Carcinoma | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Cholangiocarcinoma | Non-small Cell Lung Cancer | Primary Peritoneal Carcinoma | Hepatic Cancer | Bladder Urothelial Carcinoma | Other Solid Tumors | MSI-H Colorectal Cancer

United States
Eli Lilly and Company
ARMO BioSciences

No longer available

An Expanded Access Program for AM0010 (Pegilodecakin)

Melanoma | Renal Cell Carcinoma | Breast Cancer | Ovarian Cancer | Prostate Cancer | Non-small Cell Lung Carcinoma | Solid Tumors | Colorectal Carcinoma | Pancreatic Carcinoma
Genentech, Inc.
23andMe, Inc.

Completed

An Observational Pilot Study Evaluating the Feasibility of Conducting Genome-Wide Association Studies Utilizing Subject Provided Information in Subjects With Locally Recurrent or MBC, MCRC, MNSCLC, RGBM or MRCC Treated With Avastin (Bevacizumab) (InVite)

Breast Cancer | Glioblastoma | Colorectal Cancer | Non-Small Cell Lung Cancer | Renal Cell Cancer

United States
Sohag University

Recruiting

Acute Kidney Injury in Patients With Liver Cirrhosis

Acute Kidney Injury in Patients With Liver Cirrhosis

Egypt
Northwell Health

Recruiting

Renin Angiotensin Aldosterone System In Septic Kids (RISK)

Sepsis | Acute Kidney Injury Due to Sepsis | Acute Kidney Injury (Nontraumatic)

United States
St. Justine's Hospital
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

Outcomes of Children After Hospitalization in Intensive Care Unit (APCI)

Liver Diseases | Heart Diseases | Pneumonia | Sepsis | Septic Shock | Trauma Injury | Bronchiolitis | Renal Disease

Canada
University of Michigan

Recruiting

Erector Spinae Plane Block for Uncomplicated Renal Colic

Renal Colic | Kidney Stone

United States
University of Pittsburgh
Mayo Clinic; National Institute of Diabetes and Digestive and Kidney Diseases...

Recruiting

Restrictive Versus Liberal Rate of Extracorporeal Volume Removal Evaluation in Acute Kidney Injury (RELIEVE-AKI)

Critical Illness | Acute Kidney Injury | Hypotension | Fluid Overload | Dialysis; Complications

United States
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Several Radiation Doses for Patients With Progression on Immunotherapy/Checkpoint Inhibitors

Lung Cancer | Metastatic Cancer | Bladder Cancer | Renal Cancer | Melanoma Cancer | Head/Neck Cancers

United States
Tampere University
Finnish Cultural Foundation; Sigrid Jusélius Foundation; Päivikki and Sakari... and other collaborators

Recruiting

HaemoDYNAMICs in Primary and Secondary Hypertension (DYNAMIC)

Renal Insufficiency | Aortic Stenosis | Primary Hypertension | Secondary Hypertension

Finland
Jason J. Luke, MD
Bristol-Myers Squibb

Suspended

Safety of SBRT With Anti-PD1 and Anti-IL-8 for the Treatment of Multiple Metastases in Advanced Solid Tumors

Melanoma | Carcinoma, Renal Cell | Unresectable Solid Tumors

United States
Centre Georges Francois Leclerc

Terminated

Optimizing the Management of Patients With Oral Therapy (IPAC)

Kidney Cancer | Breast Cancer

France
University of Colorado, Denver

Active, not recruiting

Use of Direct Peritoneal Resuscitation in High-risk Liver Transplant Recipients

Obesity | Acute Kidney Injury | End Stage Liver DIsease

United States
Cardiff and Vale University Health Board

Completed

Identifying Risk Factors for Developing AKI in Sepsis

Sepsis | Acute Kidney Injury | Diabetic Ketoacidosis

United Kingdom
Shanghai Junshi Bioscience Co., Ltd.

Unknown

Tolerability and Pharmacokinetics of Toripalimab in Combination With Axitinib in Patients With Kidney Cancer and Melanoma

Advanced Melanoma | Kidney Cancer Stage Iv

China
Shenyang Northern Hospital

Withdrawn

A Randomized Trial of Rosuvastatin Loading Combined With Early hydrAtion Versus Standard-of-care Medications for the Prevention of CIAKI in Patient With AMI Undergoing Emergency PCI (TRACK-AMI)

ST Elevation Myocardial Infarction | Hydration | Contrast-induced Acute Kidney Injury | Primary PCI | Rosuvastatin

China
Hanyang University

Unknown

Effectiveness of Point of Care Blood Analysis Obtained From Skin Puncture Blood

Cardiovascular Diseases | Cerebrovascular Disorders | Respiratory Disease | Acute Abdomen | Renal Disease

Korea, Republic of
BioCryst Pharmaceuticals

Completed

A Randomized, Double-Blind, Dose-Response Study of the Safety and Uric Acid Effects of Oral Ulodesine Added to Allopurinol in Subjects With Gout and Concomitant Moderate Renal Insufficiency

Renal Insufficiency | Arthritis | Hyperuricemia | Gout | Joint Disease

United States
National Cancer Institute (NCI)
The Cleveland Clinic

Completed

Interleukin-12 and Interferon Alfa in Treating Patients With Metastatic Kidney Cancer or Malignant Melanoma

Kidney Cancer | Melanoma (Skin)

United States
Cytheris SA
Cytheris, Inc.

Terminated

Interleukin-7 in Treating Patients With Metastatic Melanoma or Locally Advanced or Metastatic Kidney Cancer

Kidney Cancer | Melanoma (Skin)

United States
Technische Universität Dresden

Completed

Effects of Rosiglitazone on Renal Hemodynamics and Proteinuria of Type 2 Diabetic Patients With Renal Insufficiency Due to Overt Diabetic Nephropathy

Type 2 Diabetes | Overt Diabetic Nephropathy

Germany
National Cancer Institute (NCI)

Completed

A Phase I Study of Infusional Paclitaxel With the P-Glycoprotein Antagonist PSC 833

Lymphoma | Carcinoma, Renal Cell | Cancer | Breast Cancer | Ovarian Cancer

United States
Assistance Publique - Hôpitaux de Paris

Terminated

IMPROVE: Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy in ANCA Associated Systemic Vasculitis

ANCA Associated Systemic Vasculitis Including Wegener's | Granulomatosis and Microscopic Polyangiitis and | Renal Limited Vasculitis

France, United Kingdom
Oregon Health and Science University
Jacobus Pharmaceutical

No longer available

3,4-Diaminopyridine for Lambert-Eaton Myasthenic Syndrome (LEMS) and Congenital Myasthenia (CM)

Lambert-Eaton Myasthenic Syndrome (LEMS) | Congenital Myasthenia (CM)

United States
Incyte Corporation

Completed

A Safety and Tolerability Study of INCAGN02390 in Select Advanced Malignancies

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Stomach Cancer | Small Cell Lung Cancer | Hepatocellular Carcinoma | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | NSCLC | Mesothelioma | Squamous Cell Carcinoma of the Head and Neck | Non-small Cell Lung Cancer | Gastroesophageal Junction Cancer | Urothelial... and other conditions

United States
Gustave Roussy, Cancer Campus, Grand Paris
Medical University of Vienna; University Hospital, Essen; Fondazione IRCCS Istituto... and other collaborators

Recruiting

CARE1 Pragmatic Clinical Trial (CARE1)

Metastatic Kidney Carcinoma | Metastatic Kidney Cancer

France
Memorial Sloan Kettering Cancer Center
Janssen Pharmaceuticals

Recruiting

A Study of CyBorD (Cyclophosphamide, Bortezomib, Dexamethasone) Plus Daratumumab in People With Monoclonal Gammopathy of Renal Significance (MGRS)

Multiple Myeloma | Monoclonal Gammopathy of Renal Significance

United States
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Not yet recruiting

A Big Data Approach to Predict NEOnatal Acute Kidney Injury in Newborns expoSed to nephroTOxic Drugs (NeoAKI STOP) (NeoAKISTOP)

Premature Birth | Acute Kidney Injury | Drug Use | Machine Learning | Newborn Morbidity | Drug Interaction | Drug Toxicity | Drug-Induced Nephropathy

Italy
University Hospital, Strasbourg, France

Recruiting

Percutaneous Cryoablation of Central Kidney Tumours With Temporary Renal Artery Occlusion (CP-Renal)

Kidney Cancer

France
Meir Medical Center

Recruiting

A Prospective Study of Clinical Factors Affecting Disease Progression and Treatment Results of Patients With Tumors of the Prostate, Bladder and Kidney.

Kidney Cancer | Prostate Cancer | Bladder Cancer

Israel
Clinical Hospital Center Rijeka
University of Rijeka

Completed

Vascular Calcifications in Kidney Transplant Recipient

Kidney Failure | Arterial Calcification | Kidney Transplant; Complications

Croatia
University of California, Davis
Academy of Nutrition and Dietetics

Active, not recruiting

Dietary Intervention to Improve Kidney Transplant Outcomes

Kidney Diseases | Hypertension | Obesity | Diabetes | Diet, Healthy | Kidney Transplant; Complications | Lifestyle, Healthy | Transplant;Failure,Kidney

United States
Yang I. Pachankis

Completed

Medicine-induced Cardiac Hemodialysis on COVID-19

Renal Dialysis | Vaccines | Infection Viral | Severe Acute Respiratory Syndrome-related Coronavirus | Myocarditis Allergic

China
Uşak University

Completed

Acute Kidney Injury in Patients With CoVID-19 (AKI-COVID-19)

Covid19 | Acute Kidney Injury

Turkey
Eloxx Pharmaceuticals, Inc.

Terminated

A Phase 2 Study of ELX-02 in Patients With Nephropathic Cystinosis

Genetic Disease | Cystinosis | Nonsense Mutation

Canada
Medical University of Warsaw

Completed

Cardiac Arrhythmias in Patients Undergoing Kidney Cancer Surgery Depending on the Anaesthesia Method

Kidney Cancer | Anesthesia, Local | Surgery | Arrhythmia, Cardiac

Poland
Philips Healthcare

Completed

The Vital Signs to Identify, Target, and Assess Level (VITAL) Care Study III

Myocardial Infarction | Renal Failure | Cardiac Arrest | Severe Sepsis | Respiration Failure

United Kingdom
University Hospital Birmingham
Ortho Biotech, Inc.; Gambro Renal Products, Inc.

Completed

European Trial of Free Light Chain Removal by Extended Haemodialysis in Cast Nephropathy (EuLITE)

Multiple Myeloma | Kidney Failure | Cast Nephropathy

United Kingdom

Clinical Trials on Abnormal Renal Function

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