Clinical Trials on Abnormalities, Multiple

Total 33406 results

Columbia University

Completed

Self-Monitoring Shopping Intervention

Intellectual Disability | Down Syndrome

United States
St. Jude Children's Research Hospital

Completed

Neurocognitive and Psychosocial Outcomes in Survivors of Childhood Leukemia With Down Syndrome

Leukemia | Down Syndrome

United States
National Cancer Institute (NCI)

Completed

Natural History and Management of Pancreatic Lesions in Von Hippel-Lindau Disease

Von Hippel-Lindau Disease

United States
National Taiwan University Hospital

Completed

Role of Sleep Apnea in the Neuropsychological Function in Down Syndrome People

Down Syndrome
Universidad Autonoma de San Luis Potosí

Unknown

Fluor Varnish With Silver Nanoparticles for Dental Remineralization in Patients With Trisomy 21

Down Syndrome

Mexico
TC Erciyes University

Terminated

The Relation Between Uric Acid Level and Endothelial Dysfunction in Patients With Polycystic Kidney Disease

Polycystic Kidney, Autosomal Dominant

Turkey
University Hospital, Grenoble

Recruiting

Down Syndrome, Physical Activity and Sleep Apnea (TAPAS)

Down Syndrome

France
King's College London
Parc de Salut Mar; Fondation Jérôme Lejeune

Recruiting

Elucidating Age-related Comorbidity Patterns in Down Syndrome (DS) (GO-DS21)

Down Syndrome

France, Spain, United Kingdom
Sequenom, Inc.

Recruiting

Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy

Down Syndrome | Fetal Aneuploidy

United States, Canada
MapHabit, Inc.
National Institute on Aging (NIA); LuMind IDSC Foundation

Completed

Life Skills Improved in Children With Down Syndrome After Using Assistive Technology

Quality of Life | Down Syndrome | Adaptive Behavior

United States
Genzyme, a Sanofi Company

Completed

Effect of Venglustat in Patients With Renal Impairment

Healthy Volunteers | Polycystic Kidney, Autosomal Dominant

United States
Vanderbilt University Medical Center

Completed

Strategies for Teaching Verbs

Down Syndrome | Language Development Disorders | Child Language

United States
Cairo University

Completed

Inspiratory Muscle Training and Physical Fitness in Children With Down Syndrome Randomized Control Trial

Down Syndrome

Egypt
Institut Jerome Lejeune
Central Hospital, Nancy, France; Hôpital Cochin

Completed

Efficacy Assessment of Systematic Treatment With Folinic Acid and Thyroid Hormone on Psychomotor Development of Down Syndrome Young Children (ACTHYF)

Down Syndrome

France
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Completed

The Role of Endothelial Dysfunction in Adult Polycystic Kidney Disease

Polycystic Kidney, Autosomal Dominant
University of Pittsburgh
National Institute on Aging (NIA)

Completed

Natural History of Amyloid Deposition in Adults With Down Syndrome

Down Syndrome

United States
Vanderbilt University
University of California, Los Angeles

Completed

Phenotypic Specific Communication Intervention for Children With Down Syndrome (Merck)

Down Syndrome | Language Impairment

United States
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Antimicrobial Photodynamic Therapy as an Adjunct Treatment for Periodontal Disease in Down's Syndrome Patients

Periodontal Diseases

Brazil
Sequenom, Inc.

Completed

Clinical Evaluation of the SEQureDx T21 Test In High Risk Pregnancies

Down Syndrome | Fetal Aneuploidy

United States, Canada
Parc de Salut Mar

Completed

Normalization of dyrk1A and APP Function as an Approach to Improve Cognitive Performance and Decelerate AD Progression in DS Subjects: Epigallocatechin Gallate as Therapeutic Tool

Down Syndrome (DS)

Spain
Mirum Pharmaceuticals, Inc.

Recruiting

Long-Term Safety and Clinical Outcomes of Livmarli in Patients With Alagille Syndrome (LEAP) (LEAP)

Alagille Syndrome

United States
Albireo

Completed

Efficacy and Safety of Odevixibat in Patients With Alagille Syndrome (ASSERT)

Alagille Syndrome

United States, United Kingdom, France, Germany, Canada, Netherlands, Italy, Malaysia, Belgium, Israel, New Zealand, Poland, Turkey
National Human Genome Research Institute (NHGRI)

Completed

Positional Cloning of the Gene(s) Responsible for Alagille Syndrome

Alagille Syndrome

United States
University of Arizona
Genentech, Inc.

Completed

Photodynamic Therapy and Vismodegib for Multiple Basal Cell Carcinomas (PDT-Vismo)

Basal Cell Carcinoma

United States
M.D. Anderson Cancer Center

Completed

Psychosocial Aspects of Multiple Endocrine Neoplasia (MEN) Syndromes

Multiple Endocrine Neoplasia

United States
Assiut University

Completed

Erector Spinae Plane Block Versus Thoracic Epidural Analgesia in Patients With Multiple Fracture Ribs

Fracture; Rib, Multiple

Egypt
Assiut University

Unknown

Oral Pregabalin Effect to the Intravenous Morphine in Multiple Fracture Ribs

Fracture; Rib, Multiple
Academisch Medisch Centrum - Universiteit van Amsterdam...
Netherlands Organisation for Scientific Research

Recruiting

Towards Optimal Treatment of Marfan Syndrome (TOWER)

Marfan Syndrome

Netherlands
University Hospital, Toulouse

Not yet recruiting

Adapted Physical Activity Program (APA) for Effort Rehabilitation of Children and Teenagers With Marfan Syndrome (M&M's)

Marfan Syndrome

France
French Cardiology Society

Completed

Effects of Personalized Training at Home Combining Endurance and Resistance in Patients Suffering From Marfan Syndrome (MARF'HOME)

Marfan Syndrome

France
Assistance Publique - Hôpitaux de Paris
Hospices Civils de Lyon; Banque de cellules cochin

Completed

Clinical Variability in Marfan Syndrome (Variarfan)

Marfan Syndrome

France
University of British Columbia
Heart and Stroke Foundation of Canada

Completed

Losartan Versus Atenolol for the Treatment of Marfan Syndrome

Marfan Syndrome

Canada
University Hospital, Antwerp
University Hospital, Ghent

Recruiting

Genome-wide Epistasis for Cardiovascular Severity in Marfan Study (GEMS)

Marfan Syndrome | FBN1 Mutation

Belgium
Baylor College of Medicine
Southern Star Research Pty Ltd.

Recruiting

Marfan Syndrome Moderate Exercise Trial II

Marfan Syndrome

United States
University Hospital, Ghent
Agentschap voor Innovatie door Wetenschap en Technologie

Completed

Randomized, Double-blind Study for the Evaluation of the Effect of Losartan Versus Placebo on Aortic Root Dilatation in Patients With Marfan Syndrome Under Treatment With Beta-blockers

Marfan Syndrome

Belgium
Stanford University
Midwestern University

Completed

Children and Adolescents With Marfan Syndrome: 10,000 Healthy Steps and Beyond

Marfan Syndrome

United States
Ann & Robert H Lurie Children's Hospital of Chicago
Johns Hopkins University

Withdrawn

Circulating Transforming Growth Factor Beta (TGF-β) in Individuals With Marfan Syndrome

Marfan Syndrome

United States
University of Oxford
Oxford University Hospitals NHS Trust

Unknown

The Oxford Marfan Trial

Marfan Syndrome

United Kingdom
Brigham and Women's Hospital
Boston Children's Hospital

Completed

Effects of Losartan Versus Atenolol on Aortic and Cardiac Muscle Stiffness in Adults With Marfan Syndrome

Marfan Syndrome

United States
EspeRare Foundation
Iqvia Pty Ltd; Pierre Fabre Medicament

Recruiting

Intraamniotic Administrations of ER004 to Male Subjects With X-linked Hypohidrotic Ectodermal Dysplasia (EDELIFE)

X-Linked Hypohidrotic Ectodermal Dysplasia (XLHED)

United States, Spain, France, Germany, Italy, United Kingdom
Mirum Pharmaceuticals, Inc.

Completed

An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Subjects With Alagille Syndrome (ALGS) (IMAGINE)

Alagille Syndrome

United Kingdom
Mirum Pharmaceuticals, Inc.
Lumena Pharmaceuticals, Inc.; Childhood Liver Disease Research and Education...

Completed

An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Pediatric Subjects With Alagille Syndrome (IMAGINE-II)

Alagille Syndrome

United States, Canada
Mirum Pharmaceuticals, Inc.

Completed

Safety and Efficacy Study of LUM001 in the Treatment of Cholestatic Liver Disease in Patients With Alagille Syndrome (IMAGO)

Alagille Syndrome

United Kingdom
Assistance Publique - Hôpitaux de Paris

Completed

Natural History of Asphyxiating Thoracic Dystrophy (DTJ) (DTJ)

Asphyxiating Thoracic Dystrophy

France
Near East University, Turkey

Completed

Myoinositol Effect on Asprosin Levels

Pregnancy Related

Cyprus
Johns Hopkins University

Completed

Effect of Broccoli Sprout Extract on Keratinocyte Differentiation in Normal Skin

Epidermolysis Bullosa Simplex | Pachyonychia Congenita

United States
Radboud University Medical Center

Unknown

Response of Immune System to Flu Vaccination in PHTS (RIPS)

PTEN Hamartoma Tumor Syndrome
Peking Union Medical College Hospital

Recruiting

68Ga-NY104 PET/CT in Von Hippel-Lindau Disease

Von Hippel-Lindau Disease

China
University of Colorado, Denver
Children's Hospital Los Angeles

Recruiting

Therapies for Down Syndrome Regression Disorder

Down Syndrome | Regression

United States
Vanderbilt University Medical Center
National Institute on Deafness and Other Communication Disorders (NIDCD)

Recruiting

Predictors of Speech Ability in Down Syndrome

Speech Intelligibility Intervention in Down Syndrome

United States

Clinical Trials on Abnormalities, Multiple

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Czech Republic

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations