Clinical Trials on Activated PI3Kdelta Syndrome (APDS); PASLI Disease

Total 853 results

Pharming Technologies B.V.

Active, not recruiting

Extension to the Study of Efficacy of CDZ173 in Patients With APDS/PASLI

Activated PI3Kdelta Syndrome (APDS); PASLI Disease

United States, Belarus, Czechia, Germany, Italy, Netherlands, Russian Federation
Novartis Pharmaceuticals

Completed

Study of Efficacy of CDZ173 in Patients With APDS/PASLI

Common Variable Immunodeficiency (CVID), APDS / PASLI

Germany, Russian Federation, Ireland, Italy, United Kingdom, Belarus, Netherlands, Czechia, United States
Children's Hospital of Fudan University

Recruiting

Rapamycin Treatment for Activated Phosphoinositide 3-Kinase δ Syndrome

Activated PI3K-delta Syndrome | Immunodeficiency Primary

China
GlaxoSmithKline

Completed

Safety, Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of Repeat Doses of Inhaled Nemiralisib in Patients With APDS/PASLI

Activated PI3K-delta Syndrome

United Kingdom
National Institute of Allergy and Infectious Diseases...

Completed

A Phase I Evaluation of Azidothymidine (AZT) in Children With Acquired Immune Deficiency Syndrome (AIDS) or AIDS Related Complex (ARC)

HIV Infections

United States
Amgen

Completed

An Open-Label Phase I/II Study of Recombinant Granulocyte Colony Stimulating Factor (r-metHuG-CSF) and Recombinant Erythropoietin (rHuEPO) Given Subcutaneously Along With Zidovudine (AZT) to Patients With the Acquired Immune Deficiency Syndrome (AIDS) or Severe AIDS-Related Complex (ARC)

HIV Infections

United States
Lederle Laboratories

Completed

A Multi-Center, Open-Label, Ascending, Multiple Oral Dose, Safety, Tolerance and Pharmacokinetic Study of 3'-Deoxy-3'-Fluorothymidine (FLT) in Patients With Acquired Immune Deficiency Syndrome (AIDS) or AIDS-Related Complex (ARC)

HIV Infections

United States
VA Eastern Colorado Health Care System
Public Health Grant Program, Veterans Health Administration Office of Public...

Completed

Veterans Living With HIV/AIDS: A Pilot Study Examining Risk Factors Associated With Self-Directed Violence

Human Immunodeficiency Virus Infection(HIV)/Acquired Immunodeficiency Syndrome (AIDS) | Self-Directed Violence

United States
Yale University
National Institute of Allergy and Infectious Diseases (NIAID); Hospital for...

Active, not recruiting

Pilot Study of Gut Commensals in Antiphospholipid Syndrome

Antiphospholipid Syndrome (APS)

United States
Ruijin Hospital

Recruiting

Effect of Telitacicept on Antibody Titers in Primary APS Patients

Antiphospholipid Syndrome (APS)

China
University Hospital, Rouen

Unknown

Study of the Efficiency of Hydroxychloroquine on the Endothelial Dysfunction and Its Vascular Consequences During the Antiphospholipid Syndrome (APLAQUINE)

Antiphospholipid Syndrome (APS)

France
University of Louisville

Completed

Increasing PrEP Among African Americans in Louisville KY

HIV/AIDS PREVENTION

United States
Columbia University
National Institute on Drug Abuse (NIDA)

Completed

Evaluating a Microfinance Intervention for Vulnerable Women in Kazakhstan (MFKZ)

HIV/AIDS and Infections

Kazakhstan
Johns Hopkins University
University of South Florida; Universidad San Francisco de Quito

Completed

Behavioral Economics Field Experiment in HIV Testing

HIV/AIDS Serodiagnosis

Ecuador
New York University
NYU Langone Health

Unknown

Adherence Connection for Counseling, Education, and Support (ACCESS)

HIV-infection/AIDS

United States
Tobira Therapeutics, Inc.
ViiV Healthcare

Completed

Study of Dolutegravir (DTG) on PK of Cenicriviroc (CVC), and CVC on PK of DTG & on a Single Dose of Midazolam

HIV-infection/AIDS

United States
Emory University
Grady Health System

Completed

Living Well Project for Persons With AIDS

Acquired Immunodeficiency Syndrome (AIDS)

United States
National Center for Women and Children's Health...
National Center for AIDS/STD Control and Prevention, China CDC; Guangdong Provincial... and other collaborators

Completed

Antiretroviral Regime for Viral Eradication in Newborns

HIV/AIDS and Infections

China
Lianne Urada
National Institute on Drug Abuse (NIDA); San Diego State University; University... and other collaborators

Completed

Effects of an HIV Intervention Among Sex Workers in the Philippines

HIV/AIDS Prevention

Philippines
University of California, Los Angeles
Yale University; Harbor Medical Inc.

Completed

Centralized Off-Site Adherence Enhancement Program (CARE)

HIV/AIDS, Medication Adherence

United States
Gaia Medical Institute
AIDS Healthcare Foundation

Completed

Rapid Oral Test for Therapeutic Response in HIV/AIDS Patients

AIDS/HIV PROBLEM

United States
University of Tartu
National Institute for Health Development, Estonia

Completed

Adherence Support Intervention for Persons Living With HIV/AIDS (PLWHA) on Antiretroviral Therapy (ART) in Estonia

HIV | Medication Adherence | AIDS

Estonia
Cook County Health

Completed

POSSE Project: A Community-Level Intervention for Black YMSM

HIV/AIDS and Infections

United States
University of South Carolina
Wayne State University; Henan University

Completed

Resilience-based Psychosocial Intervention Among Children Affected by HIV/AIDS

Emotional Adjustment | Aids/Hiv Problem

United States
Eunice Kennedy Shriver National Institute of Child...
American Association of Colleges of Pharmacy

Completed

Lopinavir/Ritonavir (Kaletra) PK in Children

HIV Infections | HIV/AIDS Treatment

United States
Johns Hopkins University
National Center for Complementary and Integrative Health (NCCIH)

Completed

American Ginseng to Improve HIV-Associated Fatigue: A Randomized, Placebo-Controlled, Parallel Design, Multiple-Dose Clinical Trial

HIV/AIDS-associated Fatigue

United States
Wolfson Medical Center

Unknown

Three Methods for Best PEEP Determination Compared With PEEP Determination Guided by Adult Respiratory Distress Syndrome (ARDS) Network

ARDS

Israel
Peking Union Medical College Hospital

Completed

Safety and Efficacy of Triptolide Wilfordii in New Onset HIV-1 Infection

HIV-infection/AIDS

China
University of Pennsylvania
Yale University; National Institute of Nursing Research (NINR); University of...

Completed

Puerto Rico Cuidalos Parent-adolescent Program

Sexually Transmitted Diseases | Pregnancy Prevention | HIV/AIDS and Infections
Biozeus Biopharmaceutical S.A.
InCor Heart Institute

Terminated

Efficacy and Safety Evaluation of BZ371B in ARDS Patients

Pulmonary Disease | ARDS | ARDS, Human

Brazil
Bicetre Hospital

Unknown

Effects of Sevoflurane on Extravascular Lung Water and Pulmonary Vascular Permeability in Patients With ARDS

ARDS | ARDS, Human
University of Padova
Città della Speranza, Padova

Completed

Kinetics of Surfactant Proteins, Phosphatidylcholine and Body Water in Intensive Care Unit (ICU)

ARDS | Sepsis Syndrome
Gilead Sciences

Terminated

Two Part Study to Evaluate Pharmacokinetics, Safety, and Antiviral Activity of Elvitegravir Administered With a PI/r Background Regimen for ARV Treatment-Experienced Pediatric Participants

HIV Infections | Acquired Immune Deficiency Syndrome (AIDS)

United States, Thailand, Spain, Uganda, South Africa, Italy
Ashley Philliber

Recruiting

The Impact of Online Educator Mircoskill Training and Parent Microskill Training on Student Sexual-Health Related Outcomes

Pregnancy Prevention | STI Prevention | HIV/AIDS Prevention

United States
Philliber Research & Evaluation

Recruiting

Evaluating the Impact of Online Educator Microskill Training on Educator Knowledge and Skill

Pregnancy Prevention | STI Prevention | HIV/AIDS Prevention

United States
ETR Associates
Dfusion Inc.

Recruiting

Evaluation of 3T, a Sex-Positive HIV/STI Mobile App Intervention for Young Black Men Ages 14-19 Attracted to Men

Sexual Behavior | Health Knowledge, Attitudes, Practice | HIV/AIDS and Infections

United States
Boston Medical Center

Completed

HIV/AIDS, Severe Mental Illness and Homelessness

HIV | AIDS

United States
Shanghai Pharmaceuticals Holding Co., Ltd

Completed

Safety and Efficacy of T8 on Treating Chronic Abnormal Immune Activation in HIV/AIDS Patients

Chronic Abnormal Immune Activation in HIV/AIDS

China
University Paris 7 - Denis Diderot
ViiV Healthcare

Recruiting

Patient-Reported Outcomes HIV BItherapy (PROBI)

Patient Preference | HIV/AIDS and Infections

France
National University, Rwanda
University of Pittsburgh; Brown University; Centers for Disease Control and Prevention and other collaborators

Unknown

Evaluation of Clinical Impacts and Costs of eHealth in Rwanda

Clinical Decision Support System | HIV/AIDS and Infections | Electronic Medical Records

Rwanda
National Cancer Institute (NCI)

Completed

A Randomized Pilot Study for the Treatment of AIDS or AIDS Related Complex With an Alternating or Simultaneous Combination Regimen of AZT and 2',3'-Dideoxyinosine

Acquired Immunodeficiency Syndrome | AIDS-Related Complex

United States
National Institute of Allergy and Infectious Diseases...

Completed

Study of People With HIV Infection Who Have High Viral Loads Despite Combination Antiretroviral Therapy

Human Immunodeficiency Virus | Acquired Immune Deficiency Syndrome Virus | Acquired Immunodeficiency Syndrome Virus | AIDS Virus | Human Immunodeficiency Viruses

United States
Bristol-Myers Squibb

Completed

A Treatment IND (Investigational New Drug) Protocol for the Use of Videx (2',3'-Dideoxyinosine, ddI) in Patients With Acquired Immunodeficiency Syndrome (AIDS) or AIDS- Related Complex (ARC) Who Are Intolerant to Zidovudine (Retrovir)

HIV Infections

United States
G D Searle
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Phase I Rising Dose Tolerability Study of SC-48334 in Patients With Acquired Immunodeficiency Syndrome (AIDS) and Advanced AIDS Related Complex

HIV Infections

United States
Gilead Sciences

Active, not recruiting

Study to Evaluate the Pharmacokinetics, Safety, and Antiviral Activity of the Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) Single Tablet Regimen (STR) in HIV-1 Infected Antiretroviral Treatment-Naive Adolescents and Virologically Suppressed Children

HIV Infections | Acquired Immune Deficiency Syndrome (AIDS)

United States, Thailand, Uganda, South Africa, Zimbabwe
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Pulmonary Complications of HIV Infection Study (PACS)

HIV Infections | Acquired Immunodeficiency Syndrome | Lung Diseases | Pneumocystis Carinii Infections | AIDS-related Complex
Columbia University
National Institute of Mental Health (NIMH)

Completed

Multi-level Determinants of Starting ART Late: Aim 2 (LSTART)

Human Immunodeficiency Virus (HIV) | Acquired Immune Deficiency Syndrome (AIDS)

Ethiopia
Institut de Recerca Biomèdica de Lleida
Instituto de Salud Carlos III

Recruiting

Longitudinal Recovery Trajectories After an Acute Respiratory Distress Syndrome, a New Understanding (TENACITY)

ARDS | ARDS Disease Progression

Spain
Assistance Publique - Hôpitaux de Paris

Recruiting

Register of Patients With Anti-Phospholipids Syndrome (APS) and/or Systemic Lupus Erythematosus (SLE) (SAPL-LUPUS)

Anti-Phospholipids Syndrome (APS) | Systemic Lupus Erythematosus (SLE)

France
Gilead Sciences

Recruiting

Study of Cobicistat-Boosted Atazanavir (ATV/co), Cobicistat-Boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in Children With HIV

HIV Infections | Acquired Immune Deficiency Syndrome (AIDS)

United States, South Africa, Argentina, Panama, Thailand, Zimbabwe, United Kingdom, Uganda

Clinical Trials on Activated PI3Kdelta Syndrome (APDS); PASLI Disease

Sponsors and Collaborators

Medical Conditions

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CROs in El Salvador

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