Clinical Trials on Acute on Chronic Hepatic Failure

Total 6185 results

Eli Lilly and Company

Completed

A Study of Evacetrapib (LY2484595) in Participants With Hepatic (Liver) Impairment

Hepatic Insufficiency

United States
Merck Sharp & Dohme LLC

Completed

Assessment of Pharmacokinetics of Single Dose Odanacatib (MK-0822) in Participants With Moderate Hepatic Insufficiency (MK-0822-070)

Hepatic Insufficiency
McGill University Health Centre/Research Institute...

Unknown

Preoperative Glucose Infusion: a Novel Strategy to Improve Liver Function After Liver Resection

Liver Failure | Hepatic Insufficiency

Canada
Korea University Anam Hospital
Pharmbio Korea Co., Ltd.

Unknown

The Effect of Somatostatin for Treatment of Post Hepatectomy Liver Failure (PHLF)

Liver Failure

Korea, Republic of
Debiopharm International SA

Completed

Evaluate the Pharmacokinetics, Safety, and Tolerability of Alisporivir in Subjects With Hepatic Impairment Compared to Healthy Subjects

Hepatic Insufficiency

United States
Virginia Commonwealth University

Withdrawn

Hepatocyte Transplantation in Liver Failure

Liver Failure

United States
Boehringer Ingelheim

Completed

Pharmacokinetics and Pharmacodynamics of BI 1356 in Subjects With Different Degrees of Liver Impairment as Compared to Healthy Subjects

Hepatic Insufficiency
Vital Therapies, Inc.

No longer available

Use of the ELAD® in Patients With Liver Failure to Provide Expanded Access With Cost Recovery

Liver Failure
Third Affiliated Hospital, Sun Yat-Sen University

Unknown

Safety and Efficacy of Diverse Mesenchymal Stem Cells Transplantation for Liver Failure

Liver Failure

China
University Hospital, Gentofte, Copenhagen

Completed

Single Dose of 9-cis-retinoic Acid in Hepatic Patients

Hepatic Insufficiency

Denmark
Bristol-Myers Squibb

Completed

Hepatic Impaired Subjects Compared to Healthy Subjects Receiving Multi-dose BMS-650032

Hepatic Insufficiency

United States
Pfizer

Completed

A Safety and Tolerability Study of CP-690,550 in Subjects With Hepatic Impairment and Normal Hepatic Function

Hepatic Insufficiency

United States
University Hospital, Grenoble

Completed

Bio-clinical Evolutive Dynamic in Patients Suffering From Communitary Septic Shock (Biosepsis) (BIOSEPSIS)

Immunocompetent Patient on Septic Shock

France
Alnylam Pharmaceuticals

Terminated

INSIGHT-AHP: A Study to Characterize the Prevalence of Acute Hepatic Porphyria (AHP) in Patients With Clinical Presentation and History Consistent With AHP

Acute Hepatic Porphyria | Acute Intermittent Porphyria (AIP) | Hereditary Coproporphyria (HCP) | Variegate Porphyria (VP) | ALA Dehydratase Deficient Porphyria (ADP) | Hepatic Porphyrias | Porphyria Acute

United States
Ahon Pharmaceutical Co., Ltd.

Recruiting

Phase 1 Hepatic Insufficiency Trial of Methoxyethyl Etomidate Hydrochloride

Hepatic Insufficiency

China
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

Registry Study for Optimal Management of Liver Failure in the Chinese Population (RESOLVE-C)

Liver Failure

China
Merck Sharp & Dohme LLC

Not yet recruiting

Ulonivirine (MK-8507) in Participants With Mild or Moderate Hepatic Impairment (MK-8507-014)

Hepatic Insufficiency
Boehringer Ingelheim

Completed

A Study to Test How Iclepertin is Taken up in the Blood of People With and Without Liver Problems

Hepatic Insufficiency

Germany
Eli Lilly and Company

Completed

A Study of Tirzepatide in Participants With Impaired Liver Function

Hepatic Insufficiency

United States
Acerta Pharma BV

Completed

A Study to Evaluate the Effect of Hepatic Insufficiency on the Pharmacokinetics (PK) of ACP-196

Hepatic Insufficiency

United States
M.D. Anderson Cancer Center

Unknown

Understanding Patient's Knowledge and Use of Acetaminophen

Liver Failure

United States
Merck Sharp & Dohme LLC
Celerion

Completed

The Influence of Hepatic Insufficiency on the Pharmacokinetics of Elbasvir (MK-8742) (MK-8742-009)

Hepatic Insufficiency

United States
Hospital Italiano de Buenos Aires

Completed

Interstage Assessment of Remnant Liver Function in ALPPS

Liver Failure

Argentina
Boehringer Ingelheim

Completed

Nintedanib in Volunteers With Hepatic Impairment Compared With Healthy Volunteers

Hepatic Insufficiency

Germany
Bristol-Myers Squibb

Completed

Single-Dose Pharmacokinetics of BMS-790052 in Participants With Hepatic Impairment

Hepatic Insufficiency

United States
Veloxis Pharmaceuticals
CTI Clinical Trial and Consulting Services; Aptuit

Completed

Pharmacokinetics of LCP-Tacro™ Once Daily and Prograf® Twice A Day in Adult De Novo Liver Transplant Patients

Liver Failure

United States
Boehringer Ingelheim

Completed

Study to Determine the Pharmacokinetics on TPV/r in Subjects With Mild and Moderate Hepatic Insufficiency

Hepatic Insufficiency
University Hospital, Gentofte, Copenhagen

Completed

Pharmacokinetics of 9-cis-retinoic Acid (Alitretinoin, Toctino®) in Patients With Hepatic Disease

Hepatic Insufficiency

Denmark
Universitaire Ziekenhuizen KU Leuven

Unknown

Citrate Anticoagulation During MARS Treatment

Liver Failure

Belgium
Novartis

Completed

Safety and Pharmacokinetics of Indacaterol in Healthy Subjects and Those With Impaired Liver Function

Hepatic Insufficiency

United States
University Health Network, Toronto

Not yet recruiting

Targeted Deprescribing in Patients on Hemodialysis

End Stage Renal Disease on Dialysis (Diagnosis)

Canada
University of Thessaly
National and Kapodistrian University of Athens

Completed

Impact of Cold Dialysis in Combination With Intradialytic Exercise in Aspects Related to Quality of Life and Health (REACD)

End Stage Renal Failure on Dialysis

Greece
Instituto Nacional de Ciencias Medicas y Nutricion...

Unknown

Effects of Cholecalciferol on Osteoprotegerin Levels in Patients on Peritoneal Dialysis

Renal Insufficiency | Vitamin D Deficiency | End Stage Renal Failure on Dialysis | Vascular Calcification

Mexico
University Hospital, Lille
Ministry of Health, France

Recruiting

Hepato Biliary Scintigraphy to Assess the Risk of Postoperative Liver Failure Hepatectomies (SCINTIVOL)

Hepatic Insufficiency

France
National Natural Science Foundation of China

Active, not recruiting

A Study on Relationship Between Resected Normal Liver Parenchymal Volume（RNLV）and Post-Hepatectomy Liver Failure (PHLF) (RNLV)

Liver Failure

China
Akdeniz University

Completed

Evaluation of HDL Subfraction Changes and HDL-Associated Enzymes in Liver Failure Patients and Healthy Donors

Liver Failure

Turkey
Hoffmann-La Roche

Completed

A Study to Investigate the Effect of Impaired Hepatic Function on the Pharmacokinetics of Entrectinib in Volunteers With Different Levels of Hepatic Function

Hepatic Insufficiency

Hungary, Czechia, Slovakia
Denovo Biopharma LLC

Completed

A Study of LY2140023 in Hepatically-Impaired Participants

Hepatic Insufficiency

Germany, Hungary
Celgene

Completed

Pharmacogenetics Sampling of the CC-90007-CP-003 Study Cohort

Hepatic Insufficiency

United States
The University of Hong Kong

Unknown

A Prospective Randomized Controlled Trial on the Use of Cerebral Oximetry in Adult Chinese Patients Undergoing Liver Transplantation (LT)

Liver Failure

Hong Kong, China
Eli Lilly and Company

Completed

A Study of Abemaciclib in Participants With Varying Degrees of Liver Impairment

Hepatic Insufficiency

United States
Humedics GmbH

Completed

Fast-track LiveR: Study for the Early Identification of Low-risk Patients After Partial Liver Resection by the LiMAx-test

Liver Failure

Germany
University of Edinburgh
NHS Lothian

Unknown

The Relationship of Initial Liver Profile and Outcome After Transplantation

Liver Failure

United Kingdom
USWM, LLC (dba US WorldMeds)
National Institute on Drug Abuse (NIDA)

Completed

Single-Dose Pharmacokinetics and Safety of Oral Lofexidine in Hepatically-Impaired Subjects

Liver Failure

United States
Stanley Dudrick's Memorial Hospital

Completed

Parenteral Lipid Emulsions and the Liver Function

Liver Failure

Poland
Veloxis Pharmaceuticals
CTI Clinical Trial and Consulting Services

Completed

Pharmacokinetics of LCP-Tacro in Stable Liver Transplant Patients

Liver Failure

United States
University Health Network, Toronto
University of Waterloo

Completed

SPME For Metabolomics And Concomitant Measurements Of Rocuronium Bromide Levels In Liver Transplantation

Liver Failure

Canada
Fundacion para la Formacion e Investigacion Sanitarias...

Completed

Extracorporeal Photopheresis After Liver Transplant

Hepatic Insufficiency

Spain
Boehringer Ingelheim

Completed

Pharmacokinetics, Safety and Tolerability of BIIL 284 BS in Patients With Hepatic Impairment in Comparison to Healthy Volunteers

Hepatic Insufficiency
Boehringer Ingelheim

Completed

Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Dabigatran Etexilate in Patients With Moderate Hepatic Impairment Compared to Subjects With Normal Hepatic Function

Hepatic Insufficiency

3

Subscribe