Clinical Trials on Acute Asthma in South Africa

Total 1020 results

University of Limpopo

Unknown

Effect of Vitamin D Supplementation on the Control of Asthma in Children at a South African Academic Hospital

Persistent Asthma

South Africa
Microbiome Health Research Institute
University of Cape Town

Terminated

Transfer of Healthy Gut Flora for Restoration of Intestinal Microbiota Via Enema for Patients in the Rehabilitative Phase of Malnutrition (THRIVE)

Moderate Acute Malnutrition | Severe Acute Malnutrition

South Africa
Aarhus University Hospital
University of Aarhus

Completed

Acute Kidney Injury After Cardiac Surgery: Novel Ultrasound Techniques for Prediction of Acute Kidney Injury

Acute Kidney Injury | Cardiac Surgery | Acute Renal Failure

Denmark, South Africa
GlaxoSmithKline

Completed

Study to Identify and Characterize Bacteria Causing Acute Otitis Media in South African Children

Acute Otitis Media

South Africa
Nova Laboratories Limited

Completed

Bioequivalence of An Oral Mercaptopurine Suspension 100 Mg / 5 Ml Versus Tablet in Healthy Male Subjects Under Fasting Conditions

Acute Lymphoblastic Leukemia

South Africa
University of Cape Town
University of KwaZulu

Unknown

African Covid-19 Critical Care Outcomes Study

Severe Acute Respiratory Syndrome Coronavirus 2

South Africa
AstraZeneca

Completed

Efficacy and Safety of Roflumilast Taken in the Morning or Evening in Patients With Stable Asthma (12 to 70 y) (BY217/M2-015)

Asthma

France, South Africa, Spain, Australia, Belgium
University of Limpopo

Unknown

Effect of Vitamin D Supplementation in Young South African Children Hospitalized With Acute Lower Respiratory Infection

Pneumonia | Bronchiolitis | Acute Lower Respiratory Tract Infection

South Africa
Novartis

Completed

Safety and Tolerability of Omalizumab in Patients With Mild to Moderate Asthma

Asthma

Germany, South Africa
University of Witwatersrand, South Africa
SynaVir

Completed

Study of Oral Administration of Ribavirin and Nitazoxamide Versus Placebo in COVID-19 (DuACT)

Covid19 | SARS-CoV Infection

South Africa
University of Cape Town
Momentum Research, Inc.

Unknown

Bi Treatment With Hydralazine/Nitrates Versus Placebo in Africans Admitted With Acute Heart Failure (B-AHEF)

Acute Heart Failure | Left Ventricular Dysfunction

South Africa
GlaxoSmithKline

Completed

Clinical Endpoint Trial Investigating Once Daily and Bronchodilator Dosing

Asthma

New Zealand, South Africa
University of Witwatersrand, South Africa

Completed

COVID-19 Prophylaxis South Africa (COVER HCW) (COVER)

Covid19 | SARS-CoV Infection

South Africa
ElectroCore INC

Terminated

Noninvasive Neurostimulation of the Vagus Nerve for the Relief of Acute Bronchoconstriction Due to Asthma (BC-SA-01)

Asthma

South Africa
Novartis
Genentech, Inc.; Tanox

Completed

A Study of Efficacy of New Doses of Xolair to Protect From Allergen Challenge in Groups of Asthma Patients Defined by IgE Levels

Asthma

Germany, Netherlands, South Africa
University of Witwatersrand, South Africa

Active, not recruiting

A Cross-sectional, Observational Study to Characterise Long COVID-19 in an Urban Sample of South African Adults (ChaLOC)

Long COVID

South Africa
Novartis Pharmaceuticals

Completed

Study to Compare the Pharmacokinetics of Mometasone Furoate Alone and in Combination With Indacaterol in Patients ≥ 6 to < 12 Years Old With Asthma

Asthma

South Africa, Hungary
The Aurum Institute NPC
Ludwig-Maximilians - University of Munich; Chris Hani Baragwanath Academic...

Completed

Tuberculosis as a Risk Factor for a Worse Outcome Post-Sars-CoV-2 Infection (Co-TB)

COVID-19 | Tuberculosis | Post-acute COVID-19 Syndrome

South Africa
AstraZeneca
Amgen

Completed

Study to Evaluate the Pharmacokinetics of Tezepelumab in Children With Asthma (TRAILHEAD)

Asthma

United Kingdom, South Africa, Hungary
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride

Acute Intermittent Porphyria | Anti-Psychotic | Management of Manifestations of Psychotic Disorders | Treatment of Schizophrenia | Control Nausea and Vomiting | Relief of Restlessness and Apprehension Before Surgery | Adjunct in the Treatment of Tetanus | Control Manifestations of the Manic Type... and other conditions

South Africa
South African National Blood Service

Unknown

Therapeutic Use of Convalescent Plasma in the Treatment of Patients With Moderate to Severe COVID-19

COVID-19 | SARS-CoV-2 Infection | Severe Acute Respiratory Syndrome Coronavirus 2

South Africa
Texas Tech University Health Sciences Center

Terminated

Use of High Frequency Chest Compression in Pediatric Status Asthmaticus

Pediatric, Asthma, Acute Exacerbation, Pediatric ICU

United States
AstraZeneca

Completed

Efficacy of Ciclesonide Inhaled Once Daily Versus Other Corticosteroids Used for Treatment of Mild Asthma in Children (4 to 11 Years) (BY9010/CA-101) (POPCICLE)

Asthma

Canada, Hungary, South Africa
University of KwaZulu
King's College London; University of Oxford; University of East Anglia; University... and other collaborators

Recruiting

ENHANCE-EvideNce Led Co-created HeAlth Systems interventioNs for MLTCs CarE (ENHANCE)

Depression | Myocardial Infarction | HIV Infections | Stroke | Hypertension | Diabetes Mellitus | Asthma

South Africa
Queen Mary University of London
National Institute for Health Research, United Kingdom

Completed

Achieving Control of Asthma in Children In Africa (ACACIA)

Asthma

Ghana, Malawi, Nigeria, South Africa, Uganda, Zimbabwe
AstraZeneca

Completed

Efficacy and Safety of Ciclesonide (CIC) Administered Twice Daily in Pediatric Patients With Asthma.

Asthma

Russian Federation, Hungary, South Africa, Mexico, United States, Poland
Merck Sharp & Dohme LLC

Completed

Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MK-1029 in Participants With Mild to Moderate Asthma

Asthma

United States, Australia, New Zealand, South Africa
University of Cape Town

Completed

the PrEsentation, Rationale and Impact of reperFUSION for Acute Coronary Syndromes in Cape Town and the Garden Route Health District - the PERFUSION Registry (PERFUSION)

Acute Coronary Syndrome | Unstable Angina | ST Elevated Myocardial Infarction | Non ST Elevation Myocardial Infarction

South Africa
University of California, Los Angeles
Fenzian Ltd.

Completed

Fenzian Asthma Multicenter Outcomes Study (FAMOUS)

Asthma

United States, South Africa, United Kingdom
AstraZeneca

Completed

Roflumilast Plus Montelukast in Adults With Severe Asthma

Asthma

Germany, South Africa, Hungary
GlaxoSmithKline

Completed

A Study in Asthmatics to Determine the Efficacy and Dose Response of Repeat Doses of GW870086X on Forced Expiratory Volume in 1 Second (FEV1)

Asthma

Germany, South Africa, Bulgaria
Boston Scientific Corporation

Completed

Bronchial Thermoplasty Global Registry (BTGR)

Asthma

Spain, Italy, Germany, Netherlands, Australia, Czechia, South Africa, United Kingdom
Sydney Children's Hospitals Network

Completed

Role of Technology in Improving Asthma Management In School Staff

Asthma in Children

Australia
Sheffield Children's NHS Foundation Trust

Completed

STudy of Asthma Adherence Reminders (STAAR)

Childhood Asthma

United Kingdom
Missouri Breaks Industries Research, Inc.
Sanford Research

Completed

Factors Influencing Pediatric Asthma (FIPA)

Asthma in Children

United States
GlaxoSmithKline

Completed

Comparing Two Respiratory Drugs in Combination and Separately From a Novel Inhaler Device in Healthy Japanese Subjects

Asthma

Australia
GlaxoSmithKline

Completed

Japanese Phase 1 Study of Mepolizumab

Asthma

Australia
GlaxoSmithKline

Completed

Comparing Two Respiratory Drugs When Used In Combination And Separately From A Novel Inhaler Device In Healthy Subjects

Asthma

Australia
GlaxoSmithKline

Completed

Study to Look at and Compare How Inhaled and Intravenous Fluticasone Furoate is Processed by the Body in Healthy Caucasian, Japanese, Korean and Chinese Subjects

Asthma

Australia
GlaxoSmithKline

Completed

Study to Look at and Compare How Inhaled and Intravenous Fluticasone Furoate and GW642444 Are Processed by the Body in Healthy Subjects

Asthma

Australia
AstraZeneca

Completed

A Study in Asthmatic Children (6 to <12 Yrs) Comparing Single Doses of Formoterol and Foradil® Evaluating Efficacy (CHASE 2)

Asthma

United States, South Africa, Hungary, Bulgaria, Czech Republic, Poland
GlaxoSmithKline

Completed

Effect of Fluticasone Furoate Inhalation Powder on the Hypothalamic-pituitary-adrenocortical Axis of Children Aged 5-11 Years With Asthma

Asthma

United States, South Africa
CSL Limited

Completed

Safety, Tolerability and Pharmacokinetics of CSL360 in the Treatment of Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML)

Australia
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Recruiting

MUlti-nuclear MR Imaging Investigation of Respiratory Disease-associated CHanges in Lung Physiology (MURDOCH)

Covid19 | Asthma | COPD | Long COVID

United Kingdom
Areteia Therapeutics

Recruiting

A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma (EXHALE-3) (EXHALE-3)

Asthma | Eosinophilic Asthma | Asthma; Eosinophilic

United States, South Africa, United Kingdom, Korea, Republic of
Medical University of South Carolina
National Institute of Nursing Research (NINR); National Institutes of Health...

Completed

Managing AsThma AnD Obesity Related Symptoms (MATADORS) Feasibility Study (MATADORS)

Obesity | Asthma in Children | Obesity, Childhood | Obesity, Adolescent

United States
University of Sydney
Melbourne Health; Royal Brisbane and Women's Hospital

Unknown

Chemotherapy Followed by Infusion of Partially HLA Matched Unrelated Donor Cells for Patients With AML Who Are Ineligible for Stem Cell Transplantation (SCRAMBLE)

Acute Myeloid Leukaemia

Australia
Wits Health Consortium (Pty) Ltd
Fred Hutchinson Cancer Center; Janssen Vaccines & Prevention B.V.; National Institute... and other collaborators

Completed

Sisonke (Together): OPEN LABEL TRIAL COVID-19 (Sisonke)

SARS (Severe Acute Respiratory Syndrome)

South Africa
University of Newcastle, Australia
GlaxoSmithKline

Unknown

Comparing Treatment Efficacy With Mepolizumab and Omalizumab in Severe Asthma - "Choosebetweenamab".

Asthma | Eosinophilic Asthma

Australia
Samsung Medical Center

Unknown

Genetic Predictive Model Based on Single Nucleotide Polymorphisms in the DNA Repair Pathway and Drug Metabolis/Transport Pharmacogenetics in the Prediction of Response and Treatment Outcomes in Acute Myeloid Leukemia

Patients With Acute Myeloid Leukemia | Patients Receiving Induction/Consolidation Chemotherapy

Korea, Republic of

Clinical Trials on Acute Asthma in South Africa

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