Clinical Trials on Acute Coronary Syndome in South Africa

Total 2251 results

Nanosphere, Inc.

Unknown

Finding Acute Coronary Syndromes (ACS) With Serial Troponin Testing for Rapid Assessment of Cardiac Ischemic Symptoms (FAST-TRAC)

Acute Coronary Syndromes

United States, Switzerland, Italy, Greece
Sheffield Teaching Hospitals NHS Foundation Trust

Withdrawn

Study of the Vascular Response to Percutaneous Coronary Intervention in Patients With Non-ST-elevation Acute Coronary Syndromes Using Intravascular Blood Sampling (IN HEART)

Non ST Segment Elevation Acute Coronary Syndrome

United Kingdom
Cerenis Therapeutics, SA
South Australian Health and Medical Research Institute

Completed

CER-001 Atherosclerosis Regression ACS Trial (CARAT)

Acute Coronary Syndromes

United States, Australia, Netherlands, Hungary
Sanofi
Bristol-Myers Squibb

Completed

Clopidogrel as Adjunctive Reperfusion Therapy - Thrombolysis in Myocardial Infarction (CLARITY-TIMI28)

Acute Coronary Syndromes

Russian Federation, Belgium, Brazil, France, Germany, Hungary, Italy, Mexico, Netherlands, South Africa, Spain, Sweden, United States, Argentina, Australia, Ireland, Israel, Turkey, Austria, Poland, Canada, Portugal, Puerto Rico, United...
University of Cape Town
University of KwaZulu

Unknown

African Covid-19 Critical Care Outcomes Study

Severe Acute Respiratory Syndrome Coronavirus 2

South Africa
University of Cape Town

Completed

the PrEsentation, Rationale and Impact of reperFUSION for Acute Coronary Syndromes in Cape Town and the Garden Route Health District - the PERFUSION Registry (PERFUSION)

Acute Coronary Syndrome | Unstable Angina | ST Elevated Myocardial Infarction | Non ST Elevation Myocardial Infarction

South Africa
AstraZeneca

Completed

LUNAR IIIb Study Comparing Rosuvastatin and Atorvastatin in Subjects With Acute Coronary Syndromes

Acute Coronary Syndromes

United States, Costa Rica, Panama, El Salvador, Morocco
AstraZeneca

Terminated

Ticagrelor vs Clopidogrel in Non-ST Elevation Acute Coronary Syndrome Patients Undergoing PCI With Bivalirudin. (NSTE-ACS)

Non-ST Elevation Acute Coronary Syndrome

United States
Heart Care Foundation
AstraZeneca; Centro Servizi ANMCO S.r.l.

Completed

EYESHOT (EmploYEd Antithrombotic Therapies in Patients With Acute Coronary Syndromes HOspitalized in iTalian Coronary Care Units) (EYESHOT)

Acute Coronary Syndromes

Italy
Microbiome Health Research Institute
University of Cape Town

Terminated

Transfer of Healthy Gut Flora for Restoration of Intestinal Microbiota Via Enema for Patients in the Rehabilitative Phase of Malnutrition (THRIVE)

Moderate Acute Malnutrition | Severe Acute Malnutrition

South Africa
Ovalum

Terminated

Study to Evaluate the Safety and Efficacy of the CiTop™ ExPander™ Guidewire for Crossing Chronic Total Occlusions in Coronary Arteries

Coronary Chronic Total Occlusion

Germany, South Africa
Bristol-Myers Squibb
Pfizer; Duke Clinical Research Institute

Completed

A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart

Acute Coronary Syndromes

Australia, Germany, Poland, United States, Spain, Brazil, France, Netherlands, Argentina, Mexico, Russian Federation, Colombia, Austria, Belgium, Czechia, Hungary, Israel, Peru, Switzerland, Korea, Republic of, Canada, Romania, Sweden, Ukrai... and more
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Efficacy of HIV Post-Test Support for ANC in South Africa (SAHAPS)

Acquired Immunodeficiency Syndrome | HIV

South Africa
Aarhus University Hospital
University of Aarhus

Completed

Acute Kidney Injury After Cardiac Surgery: Novel Ultrasound Techniques for Prediction of Acute Kidney Injury

Acute Kidney Injury | Cardiac Surgery | Acute Renal Failure

Denmark, South Africa
University of Witwatersrand, South Africa
SynaVir

Completed

Study of Oral Administration of Ribavirin and Nitazoxamide Versus Placebo in COVID-19 (DuACT)

Covid19 | SARS-CoV Infection

South Africa
University of Witwatersrand, South Africa

Completed

COVID-19 Prophylaxis South Africa (COVER HCW) (COVER)

Covid19 | SARS-CoV Infection

South Africa
South African National Blood Service

Unknown

Therapeutic Use of Convalescent Plasma in the Treatment of Patients With Moderate to Severe COVID-19

COVID-19 | SARS-CoV-2 Infection | Severe Acute Respiratory Syndrome Coronavirus 2

South Africa
The Medicines Company

Completed

A Clinical Trial Comparing Cangrelor to Clopidogrel Standard Therapy in Subjects Who Require Percutaneous Coronary Intervention (PCI) (CHAMPION PHOENIX) (CHAMPION)

Atherosclerosis | Acute Coronary Syndrome | Percutaneous Coronary Intervention

United States
Eli Lilly and Company
Daiichi Sankyo, Inc.

Completed

Effect of Prasugrel on Platelets After One Week in Patients Already Taking Clopidogrel After a Cardiac Event (SWAP)

Acute Coronary Syndrome | Coronary Arteriosclerosis

United States
University of Witwatersrand, South Africa

Active, not recruiting

A Cross-sectional, Observational Study to Characterise Long COVID-19 in an Urban Sample of South African Adults (ChaLOC)

Long COVID

South Africa
Regado Biosciences, Inc.

Completed

A Study Assessing the REG1 Anticoagulation System Compared Heparin in Subjects With Acute Coronary Syndrome (RADAR)

Acute Coronary Syndrome (ACS)

United States, Canada, Germany, France
The Aurum Institute NPC
Ludwig-Maximilians - University of Munich; Chris Hani Baragwanath Academic...

Completed

Tuberculosis as a Risk Factor for a Worse Outcome Post-Sars-CoV-2 Infection (Co-TB)

COVID-19 | Tuberculosis | Post-acute COVID-19 Syndrome

South Africa
University of Patras
Hellenic Cardiology Society

Completed

The GReek AntiPlatElet (GRAPE) Registry: A Multicenter Observational Prospective Investigation of Antiplatelet Treatment in Patients With Acute Coronary Syndrome Subjected to Percutaneous Coronary Intervention (GRAPE)

Acute Coronary Syndrome

Greece
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

WilL LOWer Dose Aspirin be More Effective Following ACS? (WILLOW-ACS) (WILLOW-ACS)

Acute Coronary Syndrome

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

The Impact of Aspirin Dose Modification on the Innate Immune Response - Will Lower Dose Aspirin Therapy Reduce the Response to Endotoxin (WILLOW TREE)

Acute Coronary Syndrome

United Kingdom
GlaxoSmithKline

Completed

Phase I Study of GW856553 (Losmapimod)

Acute Coronary Syndrome

Australia
University of Johannesburg

Completed

The Effect of Individualised Homoeopathic Treatment Using the Grant Bentley Method in Premenstrual Syndrome

Premenstrual Syndrome

South Africa
University of Johannesburg

Completed

An Observational Study on the Efficacy of Individualised Homoeopathic Treatment on Premenstrual Syndrome

Premenstrual Syndrome

South Africa
Boehringer Ingelheim

Completed

Open Label Study of NVP+CBV Treatment in Women Who Have Received sdNVP for the pMTCT of HIV

Acquired Immunodeficiency Syndrome

South Africa
Sanofi

Completed

Study of Otamixaban Versus Unfractionated Heparin (UFH) and Eptifibatide in Non-ST Elevation Acute Coronary Syndrome (SEPIA-ACS1)

Coronary Disease

United States, France, Brazil, Poland, Romania, Russian Federation, Germany, Italy, Netherlands, Portugal, Spain, Switzerland, Turkey, Bulgaria, India, Malaysia, Singapore, Slovakia, Taiwan, Czech Republic, Mexico, Argentina, Croatia, Austri... and more
University Hospital Southampton NHS Foundation...
Liverpool Heart and Chest Hospital NHS Foundation Trust

Unknown

In the Management of Coronary Artery Disease, Does Routine Pressure Wire Assessment at the Time of Coronary Angiography Affect Management Strategy, Hospital Costs and Outcomes? (RIPCORD 2)

Chest Pain | Acute Coronary Syndrome | Stable Angina | Non ST Segment Elevation Acute Coronary Syndrome

United Kingdom
University of Washington
National Institute of Mental Health (NIMH); Wits Reproductive Health and HIV...

Completed

The PrEP (Pre-exposure Prophylaxis) SMART Study

HIV/AIDS

South Africa
GlaxoSmithKline

Completed

Safety and Immunogenicity of GlaxoSmithKline Biologicals' HPV Vaccine 580299 (Cervarix) in HIV Infected Females

Infections, Papillomavirus

South Africa
Emory University
National Institute of Mental Health (NIMH); University of KwaZulu

Recruiting

Support for Adolescents Living With HIV in South Africa (InTSHA VIP)

HIV | Human Immunodeficiency Virus

South Africa
Bristol-Myers Squibb

Completed

Safety Study of Apixaban in Recent Acute Coronary Syndrome

Acute Coronary Syndrome (ACS)

Canada, Italy, Poland, Sweden, United States, Spain, Austria, Denmark, France, Belgium, Israel, Germany, Russian Federation, United Kingdom
GlaxoSmithKline

Completed

Study to Identify and Characterize Bacteria Causing Acute Otitis Media in South African Children

Acute Otitis Media

South Africa
Ortho-Clinical Diagnostics, Inc.

Unknown

VITROS Immunodiagnostic Products hs Troponin I

Myocardial Infarction | Acute Coronary Syndrome (ACS)

United States
Nova Laboratories Limited

Completed

Bioequivalence of An Oral Mercaptopurine Suspension 100 Mg / 5 Ml Versus Tablet in Healthy Male Subjects Under Fasting Conditions

Acute Lymphoblastic Leukemia

South Africa
Trinity Biotech

Completed

99th Percentile Upper Reference Limit (URL) for the Meritas Troponin I Test

Acute Coronary Syndrome

United States
University of Pennsylvania
Aurum Institute; University of Witwatersrand, South Africa

Completed

Behavioural Text Messages to Improve Retention in Care in South Africa

HIV/AIDS

South Africa
Vanderbilt University Medical Center
University of Cape Town

Completed

CareConekta: A Pilot Study of a Smartphone App in South Africa

HIV/AIDS

South Africa
Wits Health Consortium (Pty) Ltd
London School of Hygiene and Tropical Medicine; King's College London; Karolinska... and other collaborators

Completed

The CHAPS Trial: Combined HIV Adolescent PrEP and Prevention (CHAPS)

HIV/AIDS

South Africa
UMC Utrecht
ZonMw: The Netherlands Organisation for Health Research and Development; Wits... and other collaborators

Completed

The Intensified Treatment Monitoring Strategy to Prevent Accumulation of Drug Resistance (ITREMA) Trial (ITREMA)

HIV/AIDS

South Africa
Biopure Corporation

Unknown

A Study of Hemopure® to Enhance Tissue Preservation During Cardiopulmonary Bypass Surgery

Coronary Artery Disease

Greece, South Africa, United Kingdom
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Innovations in HIV Testing (TI)

Human Immunodeficiency Virus

South Africa
French National Agency for Research on AIDS and...

Completed

Pharmacokinetics of Rifabutin Combined With Antiretroviral Therapy in Patients With TB/HIV Co-infection in South Africa

HIV Infections | Tuberculosis

South Africa
Vanderbilt University
National Institute of Mental Health (NIMH); University of California, San Francisco and other collaborators

Completed

CareConekta: A Smartphone App to Improve Engagement in HIV Care

HIV/AIDS | Pregnancy Related

South Africa
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Innovations in HIV Testing (TI)

Human Immunodeficiency Virus

South Africa
Boston University
Bill and Melinda Gates Foundation; University of Witwatersrand, South Africa

Completed

Revised Simplified Algorithm for Treatment Eligibility for HIV (SLATEII) (SLATEII)

HIV/AIDS | Antiretroviral Therapy

South Africa
Boston University
National Institute of Allergy and Infectious Diseases (NIAID); University of...

Completed

Rapid Initiation of Antiretroviral Therapy to Promote Early HIV/AIDS Treatment in South Africa (RapIT Study) (RapIT)

HIV

South Africa

Clinical Trials on Acute Coronary Syndome in South Africa

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