Clinical Trials on Acute Inflammatory Response to Non-antigenic Stimulus

Total 269 results

Laval University

Completed

Effects of Maple Syrup on Gut Microbiota Diversity and Metabolic Syndrome

Overweight | Metabolic Syndrome | Insulin Resistance | Endotoxemia | Non-Alcoholic Fatty Liver Disease | Microbiota

Canada
Zhongda Hospital

Unknown

Renal Resistive Index and Cardiac Output Changes During Resuscitation Predict the Occurrence of Acute Kidney Injury in Septic Shock Patients (CORRI)

Septic Shock | Acute Kidney Injury | Critically Ill

China
Vanderbilt University Medical Center
Baxter Healthcare Corporation

Terminated

Peripheral Venous Analysis (PIVA) for Predicting Volume Responsiveness and Fluid Status (PIVA)

Systemic Inflammatory Response Syndrome | Atrial Fibrillation | Hypotension and Shock | Distributive Shock | Decompensated Congestive Heart Failure | High Risk Non-cardiac Surgery

United States
Imperial College London
Biogen; Invicro

Completed

TSPO PET as a Measure of Post-stroke Brain Inflammation: a Natural History Cohort

Inflammatory Response | Stroke, Ischemic | Stroke, Acute

United Kingdom
Kyle Kosik

Recruiting

Telehealth Delivered Physical Rehabilitation for an Ankle Sprain

Quality of Life | Acute Pain | Telerehabilitation | Implementation Science | Ankle Sprains | Analgesics, Non-narcotic | Anti-Inflammatory Agents, Non-Steroidal | Analgesic, Opioid

United States
University of Pennsylvania
Children's Hospital of Philadelphia

Completed

Study of the Tocilizumab Optimization Timing for CART19 Associated Cytokine Release Syndrome

Lymphoblastic Leukemia, Acute, Childhood

United States
Altor BioScience
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Anti-TF Antibody (ALT-836) to Treat Septic Patients With Acute Lung Injury or Acute Respiratory Distress Syndrome

Sepsis | Acute Respiratory Distress Syndrome | Acute Lung Injury

United States
Chang Gung Memorial Hospital

Unknown

EVLWI Exhibits Pulmonary and Systemic Permeability in Sepsis Related ALI/ARDS

Sepsis Related Acute Lung Injury/Acute Respiratory Distress Syndrome

Taiwan
Xinhua Hospital, Shanghai Jiao Tong University...

Unknown

Effect of R-spondin3 on Sepsis Induced Endothelial Dysfunction

Acute Respiratory Distress Syndrome (ARDS) | Acute Lung Injury (ALI)

China
Virginia Commonwealth University

Completed

Ascorbic Acid (Vitamin C) Infusion in Human Sepsis

Sepsis | Septic Shock | Hypotension | Acute Lung Injury

United States
Maimónides Biomedical Research Institute of Córdoba
Dynamic Solutions; Faes Farma, S.A.; Junta de Andalucía - Consejería de Salud...

Completed

Prevention and Treatment With Calcifediol of COVID-19 Induced Acute Respiratory Syndrome (COVIDIOL)

SARS-CoV 2 | COVID19 | Cytokine Storm | Cytokine Release Syndrome | SARS (Severe Acute Respiratory Syndrome)

Spain
King's College Hospital NHS Trust
European Society of Intensive Care Medicine; Royal Centre for Defence Medicine

Not yet recruiting

The Effect of Vasopressor Therapy on Renal Perfusion in Septic Shock (REPERFUSE)

Septic Shock | Acute Kidney Injury

United Kingdom
Clinica CES
Baxter Healthcare Corporation

Completed

RRT With a Cytokine Absorption Filter (oXiris ®) in Patients With Septic Shock

Septic Shock | Acute Kidney Injury

Colombia
University of Florida
American Society of Nephrology

Withdrawn

Impact of Pediatric Acute Renal Injury in Severe Sepsis in Young Adults (IMPRESS-YA)

Hypertension | Chronic Kidney Disease | Acute Kidney Injury
Technical University of Munich

Unknown

Cytokine Adsorption in Sepsis and Acute Kidney Injury (CASAKI)

Renal Insufficiency or Renal Failure &or End-stage Renal Disease

Germany
St. Justine's Hospital

Withdrawn

A RCT of a Combination of Analgesics for Pain Management in Children With a Suspected Fracture (CAST)

Acute Pain | Fentanyl | Analgesics, Opioid | Emergency Service, Hospital | Ibuprofen | Child/Adolescent Problem | Anti-inflammatory Agents, Non-steroidal

Canada
University of Cologne

Completed

Moxifloxacin in the Prevention of Bacteremia After High-dose Chemotherapy and Transplantation of Peripheral Stem Cells (MoxiProph)

Multiple Myeloma | Hodgkin Disease | Bacteremia | Non-Hodgkin Lymphoma

Germany
Inonu University

Not yet recruiting

VEXUS and NGAL in the Diagnosis and Prognosis of Sepsis-associated Acute Kidney Injury

Sepsis | Acute Kidney Injury
Careggi Hospital
University of Florence

Recruiting

Extracorporeal Blood Purification Therapy in Critically Ill Patients (GlobalARRT) (GlobalARRT)

Sepsis | Systemic Inflammatory Response Syndrome | Critical Illness | Acute Kidney Injury

Italy
University of Florida

Withdrawn

Long Term Impact of Pediatric Acute Renal Injury in Severe Sepsis (IMPRESS)

Hypertension | Chronic Kidney Disease | Acute Kidney Injury
Inonu University

Not yet recruiting

Can Urinary Partial Oxygen Pressure be an Indicator of Acute Kidney Injury in Patients With Sepsis?

Sepsis | Acute Kidney Injury
Nefro Consultoria de Doenças Renais Ltda
Baxter Healthcare Corporation

Active, not recruiting

Continuous Renal Replacement Therapy With Oxiris in Acute Kidney Injury and Sepsis

Sepsis | Acute Kidney Injury

Brazil
Careggi Hospital
University of Florence

Active, not recruiting

Development of a Web-based Multicenter Registry on the Use of oXiris Membrane for EBPTs in Critically Ill Patients

Sepsis | Systemic Inflammatory Response Syndrome | Critical Illness | Acute Kidney Injury

Italy
Alexander Flannery

Completed

Renin and Renal Biomarker Response to Angiotensin II

Septic Shock | Acute Kidney Injury

United States
Atox Bio Ltd

Terminated

Phase 3 Study of Reltecimod vs Placebo in Patients With Sepsis-associated Acute Kidney Injury

Acute Kidney Injury | Peritonitis | Necrotizing Soft Tissue Infection

United States, France
Qilu Hospital of Shandong University

Recruiting

Biomarkers to Predict Acute Respiratory Distress Syndrome(ARDS) in Patients With Sepsis

Sepsis

China
Moscow Regional Research and Clinical Institute...
I.M. Sechenov First Moscow State Medical University

Unknown

Effect of Inhalation Sedation Compared With Propofol on the Sepsis-related Acute Respiratory Distress Syndrome Course

ARDS

Russian Federation
Hernando Gomez
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Enrolling by invitation

Safety and Feasibility of Metformin for Sepsis Induced AKI

Sepsis | Septic Shock | Acute Kidney Injury | Metformin

United States
Istanbul University

Completed

Evaluation of Candidate Biomarkers to Predict Disease Severity and Acute Kidney Injury in Sepsis Patients

Sepsis | Septic Shock | Acute Kidney Injury

Turkey
Al-Azhar University

Unknown

Comparative Clinical Study Between Colistin-Tigecycline Combined Therapy Versus Colistin-Meropenem Combined Therapy in Treatment of Blood Stream Infections With Multidrug-Resistant Klebsiella Pneumoniae

Treatment of Blood Stream Infections Due to Multidrug-Resistant Klebsiella Pneumoniae

Egypt
Nanjing University of Traditional Chinese Medicine

Not yet recruiting

Multiple Study of Electroaccpuncture in ARDS

Sepsis | Acute Respiratory Distress Syndrome

China
Coney Island Hospital, Brooklyn, NY

Completed

Outcomes of the Use of Sodium Bicarbonate (8.4%) Solution as a Catheter Lock Solution to Prevent Hemodialysis Catheter Loss Due to Lumen Clot Formation

End Stage Renal Disease | Hemodialysis Access Failure | Hemodialysis Complication | Acute Renal Failure | Hemodialysis Catheter Infection | Hemodialysis Catheter-Associated Bacteremia
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Radiomics Markers to Predict Sepsis Induced Acute Respiratory Distress Syndrome

Early Prediction for Sepsis Induced Acute Lung Injury

China
The First Hospital of Jilin University

Not yet recruiting

Neutrophil Elastase Inhibitor in Treatment of ARDS Patients With Mechanical Ventilation Caused by Sepsis

Acute Respiratory Distress Syndrome
Poitiers University Hospital

Completed

Efficacy of Antibiotic Short Course for Bloodstream Infections in Acute Myeloid Leukemia Patients With Febrile Neutropenia

Acute Myeloid Leukemia | Febrile Neutropenia | Bloodstream Infection

France
Assiut University

Not yet recruiting

The Role of NK Cells to Detect Blood Infection in ALL.

Acute Lymphoblastic Leukemia | Bloodstream Infection
Tanta University

Recruiting

Renal Resistive Index as a Predictor of Acute Kidney Injury and Evaluation of Fluid Administration in Sepsis

Sepsis | Acute Kidney Injury | Renal Resistive Index

Egypt
Region Örebro County
University of Cambridge; Örebro University, Sweden; The Swedish Heart and Lung...

Recruiting

Effect of infLuenza vaccInation After Myocardial INfArction on Cardiac inflammaTory responsE (ELIMINATE)

Cardiovascular Diseases | Inflammatory Response | Acute Myocardial Infarction

Sweden
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Chlorhexidine Gluconate Cleansing in Preventing Central Line Associated Bloodstream Infection and Acquisition of Multi-drug Resistant Organisms in Younger Patients With Cancer or Undergoing Donor Stem Cell Transplant

Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Malignant Neoplasm | Bacterial Infection | Myeloid Neoplasm | Benign Neoplasm | Methicillin-Resistant Staphylococcus Aureus Infection

United States, Canada, Puerto Rico
Mahidol University

Completed

Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)

Septic Shock | Acute Respiratory Distress Syndrome | Acute Lung Injury | Severe Sepsis

Thailand
Xiangcheng Zhang

Recruiting

We Collected Blood Samples From Septic Shock Patients and Measured ELABELA, Creatinine, and NGAL Levels. Survival After 7 Days Was Recorded and Analyzed to Evaluate the Potential of Serum ELABELA as an Early Diagnostic Marker for Sepsis-associated Acute Kidney Injury. (ELABELA（ELA）)

Sepsis | Septic Shock | Acute Kidney Injury

China
Centre Hospitalier Universitaire de Nīmes

Recruiting

L-carnitine as an Adjunct Treatment for Septic Shock Patients With Acute Kidney Injury (CarniSave)

Shock, Septic | Acute Kidney Injury | Severe Sepsis

France
Careggi Hospital
University of Florence

Recruiting

Use of EBPT in Critically Ill Patients With AKI and/or Multiorgan Failure

Sepsis | Systemic Inflammatory Response Syndrome | Critical Illness | Acute Kidney Injury

Italy
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Ibuprofen in Sepsis Study

Lung Diseases | Shock, Septic | Acute Respiratory Distress Syndrome
University of Colorado, Denver

Completed

Identifying the Most Accurate Method for Predicting the Safe Depth of Orally Placed Neonatal Endotracheal Tubes (ETT).

Ventilator Adverse Event | Infant Showing No Response to Resuscitation | Apparent Life Threatening Event in Newborn and Infant

United States, Ireland
MedaSorb Technologies, Inc

Completed

Efficacy Study of CytoSorb Hemoperfusion Device on IL-6 Removal in ARDS/ALI Patients With Sepsis

Sepsis | Acute Respiratory Distress Syndrome | Acute Lung Injury

Germany
Lysovant

Withdrawn

ERAdicate S. Aureus in Patients With Bacteremia and Endocarditis (ERASE)

Endocarditis Infective | Bacteremia Due to Staphylococcus Aureus | Left Sided Infective Endocarditis (Disorder) | Right Sided Infective Endocarditis (Disorder)

United States
Tianjin Nankai Hospital

Active, not recruiting

Study of Biomarkers in Patients of Sepsis Complicated With Acute Respiratory Distress Syndrome (ARDS)

Sepsis | Acute Respiratory Distress Syndrome

China
Weill Medical College of Cornell University

Withdrawn

Efficacy of Bevacizumab in Preventing Acute Respiratory Distress Syndrome (ARDS) (VEGF-ARDS)

Acute Respiratory Distress Syndrome | Severe Sepsis

United States
Karolinska Institutet
University of California, San Diego; The Swedish Research Council; University... and other collaborators

Terminated

Safety and Efficacy of Hyperbaric Oxygen for ARDS in Patients With COVID-19 (COVID-19-HBO)

COVID-19 | Cytokine Storm | SARS (Severe Acute Respiratory Syndrome) | Acute Respiratory Failure | ARDS, Human | Sars-CoV2

Sweden, Germany

Clinical Trials on Acute Inflammatory Response to Non-antigenic Stimulus

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