Clinical Trials on Acute Intermittent Porphyria

Total 15908 results

Shanghai General Hospital, Shanghai Jiao Tong University...

Recruiting

Anti-CD7 CAR-T Cell Therapy for Relapse and Refractory CD7 Positive T Cell Malignancies

Anaplastic Large Cell Lymphoma | Angioimmunoblastic T-cell Lymphoma | Peripheral T Cell Lymphoma | T-cell Acute Lymphoblastic Leukemia | T Lymphoblastic Leukemia/Lymphoma

China
University Hospital, Basel, Switzerland

Completed

NK DLI in Patients After Human Leukocyte Antigen (HLA)-Haploidentical Hematopoietic Stem Cell Transplantation (HSCT)

Lymphoma | Myelodysplastic Syndromes | Leukemia, Myeloid, Acute | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Neuroblastoma | Rhabdomyosarcoma

Switzerland, Germany
Medela AG
Joseph M. Still Research Foundation, Inc.

Completed

A Dual-center Study Evaluating Clinical Acceptance of a NPWT Wound Care System

Edema | Surgical Wound | Diabetic Foot Ulcer | Pressure Ulcer | Pressure Injury | Acute Wound | Traumatic Wound | Dehiscence

United States
Aarhus University Hospital

Withdrawn

COVID-19 Prevalence and Cognitive Deficits in Neurological Patients (Neuro-Covid)

Stroke, Acute | Seizure Disorder | Neurological Diseases or Conditions

Denmark
University of Sao Paulo General Hospital

Completed

Characteristics and Outcomes of Patients With COVID-19 Admitted to the ICU (EpiCoV-Brazil)

SARS-CoV 2 | Critical Illness | Corona Virus Infection | Respiratory Distress Syndrome, Adult

Brazil
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Improving Blood Stem Cell Collection and Transplant Procedures

Acute Lymphoblastic Leukemia | Chronic Myelogenous Leukemia | Myelodysplastic Syndrome (MDS) | CLL (Chronic Lymphocytic Leukemia) | CML (Chronic Myelogenous Leukemia

United States
Alaunos Therapeutics

Completed

A Phase I Trial of ZIO-101 in Hematologic Cancers

Lymphoma | Multiple Myeloma | Acute Leukemia | Chronic Myeloproliferative Disease | Chronic Lymphoproliferative Disease | Poor-risk Myelodysplasia (MDS)

United States
University Hospital, Grenoble

Unknown

Comparative Study of Arterial Properties After an Ischaemic Stroke or an Acute Coronary Syndrome (AVC/SCA)

Obstructive Sleep Apnea Syndrome | Ischemic Stroke | Acute Coronary Syndrome

France
University of Nebraska
National Cancer Institute (NCI)

Terminated

Rituximab in Preventing Acute Graft-Versus-Host Disease in a Donor Stem Cell Transplant for Hematologic Cancer

Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent... and other conditions

United States
Mayo Clinic

Recruiting

Understanding the Risk of Blood Clots and Bleeding in Patients With Hematological Malignancies, HAT Study

Hematopoietic and Lymphoid Cell Neoplasm | Hodgkin Lymphoma | Thrombocytopenia | Deep Vein Thrombosis | Non-Hodgkin Lymphoma | Acute Leukemia | Plasma Cell Myeloma | Myeloproliferative Neoplasm

United States
An-Najah National University

Completed

Distal vs. Forearm Radial Artery Access (DRAvsFRA)

Myocardial Infarction | Myocardial Ischemia | Coronary Artery Disease | Chest Pain | Angina, Stable | Acute Coronary Syndrome | Angina, Unstable | Non ST Segment Elevation Myocardial Infarction | ST-segment Elevation Myocardial Infarction (STEMI) | Non STEMI | Atheroscleroses, Coronary | Atherosclerotic Heart...

Palestinian Territory, occupied
Istanbul University - Cerrahpasa (IUC)

Withdrawn

Comparison of Extra Vascular Lung Water Index in Covid-19 ARDS and "Typical"ARDS Patients

Covid19 | Respiratory Distress Syndrome, Adult | Pulmonary Edema | Ventilation Perfusion Mismatch

Turkey
University of Maryland, Baltimore

Withdrawn

Pilot RCT of Therapeutic Hypothermia Plus Neuromuscular Blockade in COVID-19 Patients With ARDS (CHILL-pilot)

Respiratory Distress Syndrome, Adult | Sars-CoV2

United States
CENTOGENE GmbH Rostock

Withdrawn

Fabry and Cardiomyopathy (FaCard) (FaCard)

Stroke, Acute | Cerebrovascular Accident | Cerebral Stroke

Germany
Masonic Cancer Center, University of Minnesota

Terminated

Reduced Intensity Conditioning and Haploidentical Related Bone Marrow for Patients With Hematologic Diseases

Chronic Myelogenous Leukemia | Acute Leukemias | Burkitt's Lymphoma

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Unknown

PRedictOrs, PHEnotypes and Timing of Obstructive Sleep Apnea in Acute Coronary Syndrome (PROPHET-ACS)

Sleep | ST Elevated Myocardial Infarction | Sleep-Disordered Breathing | NSTEMI - Non-ST Segment Elevation MI

Italy
Cardiologie et Développement
Institut National de la Santé Et de la Recherche Médicale, France

Unknown

A Survey of Hospitalizations in Cardiology Units in Sub-Saharan Africa (FEVRIER)

Heart Failure | Stroke | Syncope | Acute Coronary Syndrome | Deep Vein Thrombosis | Pericarditis | Endocarditis | Pulmonary Embolism | Conduction Abnormalities | Rhythm; Abnormal | Other Cardiovascular Conditions

Benin, Burkina Faso, Burundi, Cameroon, Congo, The Democratic Republic of the, Congo, Côte D'Ivoire, Gabon, Guinea, Mozambique, Niger, Senegal, Sudan
Adelphi Values LLC
Blueprint Medicines Corporation

Completed

Patient-Reported Outcome Questionnaire for Systemic Mastocytosis

Mast Cell Leukemia (MCL) | Aggressive Systemic Mastocytosis (ASM) | SM w Assoc Clonal Hema Non-mast Cell Lineage Disease (SM-AHNMD) | Smoldering Systemic Mastocytosis (SSM) | Indolent Systemic Mastocytosis (ISM) ISM Subgroup Fully Recruited

United States
Celgene Corporation

Terminated

Phase 1 Study of CC-486 in Japanese Subjects With Hematological Neoplasms

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Multiple Myeloma | Hodgkin Lymphoma | Chronic Myelomonocytic Leukemia | Non-Hodgkin Lymphoma

Japan
Bayside Health

Completed

Australia and New Zealand Adult Extracorporeal Membrane Oxygenation (ECMO) Audit 2005

Respiratory Insufficiency | Shock, Cardiogenic | Respiratory Distress Syndrome, Adult

Australia
Icahn School of Medicine at Mount Sinai
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

CTSN Embolic Protection Trial

Coronary Artery Disease | Delirium | Ischemic Stroke | Acute Kidney Injury | Heart Valve Disease

United States, Canada
London School of Hygiene and Tropical Medicine
University of Ibadan; University of Zimbabwe; University of Malawi; University... and other collaborators

Recruiting

SUCCEED Africa: Support, Comprehensive Care and Empowerment of People With Psychosocial Disabilities (SUCCEED)

Schizophrenia | Schizoaffective Disorder | Delusional Disorder | Schizotypal Disorder | Acute and Transient Psychotic Disorder | Other Specified or Unspecified Primary Psychotic Disorder | Bipolar Type I Disorder With Psychotic Symptoms | Bipolar Type II Disorder With Psychotic Symptoms | Single Episode... and other conditions

Malawi, Nigeria, Sierra Leone, Zimbabwe
Memorial Sloan Kettering Cancer Center
Actinium Pharmaceuticals

Recruiting

Iomab-ACT: A Pilot Study of 131-I Apamistamab Followed by CD19-Targeted CAR T-Cell Therapy for Patients With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia or Diffuse Large B-Cell Lymphoma

Diffuse Large B-cell Lymphoma | B-ALL | DLBCL | DLBCL, Nos Genetic Subtypes | B ALL | Dlbcl-Ci | DLBCL Unclassifiable | DLBCL Activated B-Cell Type | DLBCL Germinal Center B-Cell Type | HGBL | HGBL, Nos

United States
Gary M Brittenham, MD

Active, not recruiting

Daily Vitamin D for Sickle-cell Respiratory Complications (ViDAS-2)

Respiratory Tract Infections | Respiratory Tract Diseases | Respiration Disorders | Lung Diseases | Nutrition Disorders | Vitamin D Deficiency | Asthma | Sickle Cell Disease | Anemia, Sickle Cell | Anemia, Hemolytic, Congenital | Acute Chest Syndrome | Deficiency Diseases Vitamin

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Active, not recruiting

CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide Gene (CASPALLO)

Non-Hodgkin's Lymphoma | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia | Myelodysplastic Syndrome

United States
3M

Withdrawn

Clinical Evaluation of the SNaP Wound Care System

Diabetic Foot Ulcers | Venous Stasis Ulcers | Pressure Ulcers | Trauma Wounds | Acute and Chronic Wounds

United States
Hôpital de Verdun

Completed

COVid-19: Awake Proning and High-flow Nasal Cannula in respiratorY DistrEss (COVAYDE)

Severe Acute Respiratory Syndrome | Coronavirus Infection | Lung Diseases | Respiratory Failure | Respiratory Insufficiency | COVID | Respiratory Distress Syndrome | ARDS

Canada
Rempex (a wholly owned subsidiary of Melinta Therapeutics...
Department of Health and Human Services

Completed

Efficacy, Safety, Tolerability of Vabomere Compared to Best Available Therapy in Treating Serious Infections in Adults

Bacteremia | Acute Pyelonephritis | Ventilator-associated Bacterial Pneumonia | Urinary Tract Infection Complicated | Hospital Acquired Bacterial Pneumonia | Abdominal Infection

Italy, United States, Colombia, Greece, Israel, Brazil, Argentina, United Kingdom
Assistance Publique - Hôpitaux de Paris
Ministry of Health, France

Withdrawn

Pre Hospital Evaluation of Video Laryngoscopy (EVE)

Shock | Trauma, Nervous System | Cardiac Arrest | Respiratory Distress Syndrome | Drug Toxicity | Acute Post-trauma Stress State
New York Medical College

Completed

Human Placental-Derived Stem Cell Transplantation (HPDSC)

Mucopolysaccharidosis I | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Niemann-Pick Disease | Mucopolysaccharidosis VI | Wolman Disease | Adrenoleukodystrophy | Batten Disease | Metachromatic Leukodystrophy | Diamond-Blackfan Anemia | Severe Aplastic Anemia | Fucosidosis | Gaucher... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Genetically Modified T-Cell Therapy in Treating Patients With Advanced ROR1+ Malignancies

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Recurrent Mantle Cell Lymphoma | Metastatic Lung Non-Small Cell Carcinoma | Refractory Chronic Lymphocytic Leukemia | Stage IIIA Lung Non-Small Cell Cancer AJCC v7 | Recurrent Acute Lymphoblastic Leukemia | Metastatic Triple-Negative... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Withdrawn

Rituximab, Romidepsin, and Lenalidomide in Treating Patients With Recurrent or Refractory B-cell Non-Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions
U.S. Wound Registry
Undersea and Hyperbaric Medical Society (UHMS)

Unknown

Hyperbaric Oxygen Therapy Registry (HBOTR)

Carbon Monoxide Poisoning | Decompression Sickness | Severe Anemia | Idiopathic Sudden Sensorineural Hearing Loss | Necrotizing Soft Tissue Infections | Air or Gas Embolism | Clostridial Myositis and Myonecrosis (Gas Gangrene) | Crush Injury, Compartment Syndrome & Other Acute Traumatic Ischemias | Peripheral... and other conditions
Uniformed Services University of the Health Sciences

Recruiting

Ivabradine for Long-Term Effects of COVID-19 With POTS Cohort (COVIVA)

Postural Orthostatic Tachycardia Syndrome | Long Haul COVID

United States
University of California, Los Angeles
Brigham and Women's Hospital; University of California, San Francisco; Antelope...

Recruiting

Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients (NEXUS AP CT)

Hip Injuries | Pelvic Fracture | Bowel Disease | Aortic Dissection | Aortic Rupture | Abdominal Injury | Lumbar Spine Injury | Vascular System Injuries | Diaphragm Injury | Liver Injury | Spleen Injury | Renal Injury | Sacral Fracture | Genital Hemorrhage

United States
I.M. Sechenov First Moscow State Medical University

Recruiting

Contrast-associated Acute Kidney Injury in Patients With Different Types of Coronary Artery Disease

Coronary Artery Disease | Angina, Stable | Acute Kidney Injury | Angina, Unstable | Contrast-induced Nephropathy | NSTEMI - Non-ST Segment Elevation MI | STEMI - ST Elevation Myocardial Infarction

Russian Federation
NHS Lothian
University of Edinburgh

Recruiting

Traumatic Brain Injury Associated Radiological DVT Incidence and Significance Study (TARDIS)

Traumatic Brain Injury | Deep Vein Thrombosis | Acute Lung Injury | Ventilator Associated Pneumonia

United Kingdom
University of Rochester

Recruiting

Umbilical Cord Blood Transplantation From Unrelated Donors

Lymphoma | Myelodysplastic Syndromes | Multiple Myeloma | Solid Tumor | Acute Leukemia | Aplastic Anemia | Chronic Leukemia | Immune Deficiency Disorder | Congenital Hematological Disorder | Metabolism Disorder

United States
University of Arkansas

Withdrawn

PK and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia

Acute Kidney Injury | Hypoxic-Ischemic Encephalopathy | Caffeine

United States
Rutgers, The State University of New Jersey

Completed

Safety and Feasibility of the Infinity Catheter for Radial Access

Carotid Stenosis | Brain Tumor | Stroke, Acute | Intracranial Arteriovenous Malformations | Brain Aneurysm | Cavernous Sinus Thrombosis

United States
Leidos Life Sciences
United States Department of Defense

Active, not recruiting

LEAP-CT for Treatment of COVID-19 Patients (Master Protocol)

COVID-19 | Covid19 | Coronavirus Disease 2019 | SARS-CoV-2 Infection | SARS-CoV-2 Acute Respiratory Disease | COVID-19 Pandemic | COVID-19 Virus Infection | COVID-19 Virus Disease | 2019 Novel Coronavirus Disease | 2019 Novel Coronavirus Infection | 2019-nCoV Disease | 2019-nCoV Infection

United States
Lviv National Medical University

Completed

ERECTOR SPINE PLANE BLOCK VERSUS LOCAL INFILTRATION ANAESTHESIA FOR TRANSFORAMINAL PERCUTANEOUS ENDOSCOPIC DISCECTOMY

Chronic Pain | Postoperative Pain | Anesthesia, Local | Postoperative Cognitive Dysfunction | Acute Pain | Neuropathic Pain | Anesthesia | Postoperative Nausea and Vomiting | Intraoperative Complications | Hyperalgesia | Regional Anesthesia Morbidity | Anesthesia Complication | Intraoperative Injury | Intraoperative...

Ukraine
Robert Lowsky
National Cancer Institute (NCI)

Completed

CD8+ Memory T-Cells as Consolidative Therapy After Donor Non-myeloablative Hematopoietic Cell Transplant in Treating Patients With Leukemia or Lymphoma

Acute Myeloid Leukemia | Hodgkin Lymphoma | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | B-Cell Non-Hodgkin Lymphoma | Myeloproliferative Neoplasm | T-Cell Non-Hodgkin Lymphoma

United States
Beijing Anzhen Hospital

Completed

Tissue Oxygenation During Treatment of Infant Congenital Heart Defects

Acute Kidney Injury | Hypoxia-Ischemia, Brain | Mesenteric Ischemia

China
University of Texas at Austin

Unknown

Peer Support for Post Intensive Care Syndrome Self-Management (PS-PICS)

Sepsis | Shock | Critical Illness | Shock, Septic | Respiratory Failure | Chronic Disease | Respiratory Distress Syndrome, Adult | Shock, Hypovolemic

United States
Cloud DX Inc.

Completed

Preliminary Testing of the Vitaliti CVSM Wearable, Vitaliti Spirotoscope, and Vitaliti IVD Station

Pneumonia | Hypertension | Diabetes Mellitus | Atrial Fibrillation | Urinary Tract Infection | Healthy Volunteers | OSA | COPD | Leukocytosis | Acute Otitis Media | Iron Deficient Anemia

Canada
Washington University School of Medicine
CTI BioPharma

Withdrawn

Pacritinib in Combination With Low Dose Decitabine in Intermediate-High Risk Myelofibrosis or Myeloproliferative Neoplasm (MPN)/Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndromes | Myelofibrosis | Chronic Myelomonocytic Leukemia | Juvenile Myelomonocytic Leukemia | Myeloproliferative Neoplasm | Atypical Chronic Myeloid Leukemia
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
The First People's Hospital of Hefei; Hefei Binhu Hospital

Unknown

PCAR-119 Bridge Immunotherapy Prior to Stem Cell Transplant in Treating Patients With CD19 Positive Leukemia and Lymphoma

Follicular Lymphoma | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Acute Lymphocytic Leukemia | Diffuse Large Cell Lymphoma | B-cell Prolymphocytic Leukemia

China
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
Anhui Provincial Hospital

Unknown

Study Evaluating the Efficacy and Safety of PCAR-019 in CD19 Positive Relapsed or Refractory Leukemia and Lymphoma

Follicular Lymphoma | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Acute Lymphocytic Leukemia | Diffuse Large Cell Lymphoma | B-cell Prolymphocytic Leukemia

China
Federal Research Institute of Pediatric Hematology...

Completed

Memory T-cell Infusion to Improve Immunity After TCR-alpha/Beta Depleted Hematopoietic Stem Cell Transplantation (45RA_NEG_DLI)

Leukemia, Myeloid, Acute | Opportunistic Infections | Graft vs Host Disease | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma | Bone Marrow Failure Syndromes | Immune Deficiency Disease

Russian Federation

Clinical Trials on Acute Intermittent Porphyria

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