Clinical Trials on Advanced Cancer Entities

Total 54042 results

Aminex Therapeutics, Inc.

Completed

Oral AMXT 1501 Dicaprate in Combination With DFMO

Cancer | Solid Tumor | Advanced Cancer | Solid Carcinoma

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

A Study of Anlotinib and AK105 Injection in Subjects With Advanced Head, Neck and Chest Cancer

Advanced Head, Neck and Chest Cancer

China
GeneScience Pharmaceuticals Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; Tongji Hospital and other collaborators

Unknown

A Study of Gentuximab + Paclitaxel in Patients With Advanced Gastric or Gastroesophageal Junction Cancer

Advanced Gastric or Gastroesophageal Junction Cancer

China
TaiRx, Inc.

Completed

Safety and Pharmacokinetic Study of TRX-818 in Asian Solid Tumor Patients

Carcinoma | Advanced Cancer

Taiwan
Bristol-Myers Squibb
Ono Pharmaceutical Co. Ltd

Completed

An Investigational Immuno-therapy Study to Investigate the Safety and Effectiveness of Nivolumab, and Nivolumab Combination Therapy in Virus-associated Tumors (CheckMate358)

Various Advanced Cancer

United States, Belgium, France, Germany, Japan, Korea, Republic of, Mexico, Netherlands, Spain, Taiwan, United Kingdom
Southern Europe New Drug Organization
Clinical Trial Unit Ente Ospedaliero Cantonale

Completed

Study to Investigate the Efficacy of Panitumumab in Platinum-resistant Advanced Head and Neck Squamous Cancer (S10PANI01)

Advanced Head and Neck Squamous Cancer
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Caregiver Assessments of the Quality of Home Hospice Care

Advanced Cancer

United States
University of California, San Francisco
Merck Sharp & Dohme LLC

Completed

MK-2206, Paclitaxel and Trastuzumab in Treating Patients With HER2-overexpressing Solid Tumor Malignancies

Cancer | Advanced Solid Tumors | Tumors

United States
M.D. Anderson Cancer Center

Completed

HAI Irinotecan + IV Bevacizumab, Bevacizumab & Oxaliplatin or Bevacizumab & Cetuximab in Advanced Cancers Metastatic to Liver

Advanced Cancer | Liver Cancer

United States
ImmuneOnco Biopharmaceuticals (Shanghai) Inc.

Recruiting

IMM2902, a HER2/SIRPα Bispecific mAb-Trap Antibody-receptor Fusion Protein, in Patients With HER2-expressing Advanced Solid Tumors

Advanced Breast Cancer | Advanced Solid Tumor | Advanced Gastric Cancer

United States
M.D. Anderson Cancer Center
GlaxoSmithKline; National Comprehensive Cancer Network

Completed

Pazopanib and Everolimus in PI3KCA Mutation Positive/PTEN Loss Patients

Solid Tumors | Advanced Cancers

United States
University Health Network, Toronto

Active, not recruiting

Immunotherapy And Palliative Radiotherapy Combined In Patients With Advanced Malignancy

Advanced Cancer | Immunotherapy | Radiation Therapy | Palliative

Canada
Massachusetts General Hospital

Completed

Care Transition Intervention for Patients With Cancer

Advanced Cancer | Home Care, Hospital-Based

United States
Novartis Pharmaceuticals

Terminated

Phase I Study to Determine the Maximum Tolerate Dose (MTD) of BGT226 in Advanced Solid Tumors in Japan

Cancer | Solid Tumor | Advanced Solid Tumor

Japan
Ascenta Therapeutics

Terminated

An Open-label, Single-center, Phase 1/ 2 Study of Chemoradiotherapy and AT-101 in Patients With Locally Advanced Esophageal or Gastroesophageal Junction Cancer

Locally Advanced Esophageal or GE Junction Cancer

United States
AstraZeneca

Completed

Study to Assess the Safety and Tolerability of the Tor Kinase Inhibitor AZD8055

Cancer | Solid Tumors | Advanced Solid Malignancies

Japan
AstraZeneca

Terminated

Safety and Tolerability Study of AZD7762 in Combination With Gemcitabine

Cancer | Solid Tumors | Advanced Solid Malignancies

Japan
Memorial Sloan Kettering Cancer Center
Array BioPharma

Completed

A Study of Binimetinib and Encorafenib in Advanced BRAF Mutant Cancers

Advanced BRAF Mutant Cancers

United States
M.D. Anderson Cancer Center

Completed

Registry Study for Personalized Cancer Therapy

Solid Tumors | Advanced Cancers

United States
Fondazione IRCCS Policlinico San Matteo di Pavia
University of Pavia

Recruiting

Lymphocyte Enhancement in Gastroenteric Oncology

Advanced Gastrointestinal Cancers

Italy
National Taiwan University Hospital

Not yet recruiting

Valuation of the Safety and Efficacy of Combination of Cryoablation and Dendric Cell/Cytokine-induced Killers Cells Treatment for Advanced Liver Cancers

Advanced Liver Cancers
Jules Bordet Institute
Université Libre de Bruxelles; Fonds Gaston Ithier; Association Jules Bordet

Recruiting

Advanced Cancer Patients' and Their Primary Caregivers' Willingness to Communicate About Advance Care Planning (ACP)

Advanced Cancer

Belgium
Gilead Sciences
Everest Medicines

Active, not recruiting

Study of Sacituzumab Govitecan-hziy (IMMU-132) Versus Treatment of Physician's Choice in Participants With Metastatic or Locally Advanced Unresectable Urothelial Cancer (TROPiCS-04)

Locally Advanced or Metastatic Unresectable Urothelial Cancer

United States, Belgium, France, Spain, United Kingdom, Korea, Republic of, Czechia, Germany, Israel, China, Italy, Australia, Hong Kong, Taiwan, Portugal, Singapore, Croatia, Greece, Turkey, Sweden, Switzerland, Canada, Austria, Bulgaria and more
M.D. Anderson Cancer Center

Completed

Vemurafenib in Combination With Everolimus or Temsirolimus With Advanced Cancer

Solid Tumor | Advanced Cancer

United States
AstraZeneca

Terminated

Study is Designed to Assess the Safety and Tolerability of AZD4547 at Increasing Doses in Patients With Advanced Tumours

Cancer | Advanced Solid Malignancies

United States, Italy, United Kingdom, France, Germany, Spain, Netherlands
AstraZeneca

Terminated

Phase I, Open-label, Dose-escalation, Safety and PK Study of AZD6918

Solid Tumors | Advanced Solid Malignancies | Cancer,

United States
NKGen Biotech, Inc.

Active, not recruiting

Safety of SNK01 in Subjects With Pathologically Confirmed Metastatic and/or Unresectable Cancer Refractory to Conventional Therapy

Metastatic Cancer | Advanced Solid Tumor | Advanced Cancer | Solid Tumor, Adult | Refractory Cancer | Recurrent Cancer | Unresectable Carcinoma

United States
Abramson Cancer Center at Penn Medicine

Active, not recruiting

HOPE: Olaparib, Palbociclib and Fulvestrant in Patients With BRCA Mutation-associated, HR+, HER2-metastatic Breast Cancer

Advanced Breast Cancer | Metastatic Breast Cancer | BRCA1 Mutation | BRCA2 Mutation | Locally Advanced Breast Cancer

United States
Hoffmann-La Roche
Tempest Therapeutics; Adagene Inc

Recruiting

A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)

Advanced Liver Cancers

Korea, Republic of, Taiwan, United States, Israel, China, France, New Zealand
Royal Marsden NHS Foundation Trust

Unknown

Feasibility of a Molecular Characterisation Approach to Treatment (FOrMAT)

Advanced Gastrointestinal Cancers

United Kingdom
NKGen Biotech, Inc.

Active, not recruiting

Study of Allogeneic Blood-derived Natural Killer Cells to Evaluate Safety and Tolerability in Cancer Refractory to Conventional Therapy

Solid Tumor | Metastatic Cancer | Advanced Solid Tumor | Advanced Cancer | Solid Tumor, Adult | Refractory Cancer | Recurrent Cancer | Pathologically Confirmed Cancer Refractory to Conventional Therapy

United States
M.D. Anderson Cancer Center

Completed

Erlotinib in Combination With Pralatrexate in Advanced Malignancies

Solid Tumors | Advanced Cancers

United States
University College, London

Not yet recruiting

Prognostic Understanding in ESC (ProgESC Study)

Advanced Cancer
Wuxi People's Hospital

Recruiting

A Clinical Study of Intratumoral Administration of RT-01 in Patients With Advanced Solid Tumors

Solid Tumor | Advanced Cancer

China
Daiichi Sankyo Co., Ltd.

Recruiting

A Study Evaluating DS-1055a in Participants With Relapsed or Refractory Locally Advanced or Metastatic Solid Tumors

Solid Tumor | Metastatic Solid Tumor | Advanced Cancer

Japan, United States, Canada
Merck Sharp & Dohme LLC

Completed

Dose Escalation Study With MK-2206 in Patients With Locally Advanced or Metastatic Solid Tumors (MK-2206-002)

Neoplasms | Cancer | Metastatic Solid Tumors | Locally Advanced Tumors
M.D. Anderson Cancer Center
Pfizer

Terminated

The Effect of Donepezil on Sedation and Other Symptoms

Advanced Cancer

United States
Northwestern University
National Cancer Institute (NCI)

Not yet recruiting

Elacestrant vs Elacestrant Plus a CDK4/6 Inhibitor in Patients With ERpositive/HER2-negative Advanced or Metastatic Breast Cancer

Metastatic Breast Cancer | Estrogen-receptor-positive Breast Cancer | HER2/Neu-Negative Breast Cancer | Advanced Breast Cancerv

United States
Cornerstone Pharmaceuticals

Completed

A Open Label Phase I/II Clinical Trial to Evaluate CPI-613 in Patients With Advanced Malignancies

Lymphoma | Metastatic Cancer | Advanced Cancer | Solid Tumors | Advanced Malignancies

United States, Canada
Nectin Therapeutics Ltd
Merck Sharp & Dohme LLC

Recruiting

A Study of NTX-1088, a Monoclonal Antibody Targeting the Poliovirus Receptor (PVR, CD155), as Monotherapy and Combined With Pembrolizumab

Cancer | Metastatic Cancer | Advanced Solid Tumor | Tumor, Solid | Locally Advanced Solid Tumor

United States, Israel
Parker Institute for Cancer Immunotherapy
Bristol-Myers Squibb; Cancer Research Institute, New York City

Completed

Nivolumab With or Without Ipilimumab in Advanced Metastatic Cancer

Advanced Metastatic Cancer | Advanced Prostate Cancer

United States
Puma Biotechnology, Inc.

Completed

A Phase 1/2 Study of HKI-272 (Neratinib) in Combination With Paclitaxel (Taxol) in Subjects With Solid Tumors and Breast Cancer

Breast Neoplasms | Advanced Breast Cancer | Advanced Malignant Solid Tumors

United States, Belgium, China, Hong Kong, Canada, Korea, Republic of, India, Poland, Ukraine
Bien-Willner Physicians Group PA
No One Left Alone; Carolina Blood and Cancer Care Associates

Not yet recruiting

Molecular Services and EMR-Lab Integration Application (ELIA) for Reducing Healthcare Disparities in Cancer Patients

Advanced Cancer | Myeloid Malignancy | Solid Tumor, Adult

United States
Bristol-Myers Squibb
Ono Pharmaceutical Co. Ltd

Active, not recruiting

An Investigational Immuno-therapy Study of Nivolumab, Compared to Placebo, in Patients With Bladder or Upper Urinary Tract Cancer, Following Surgery to Remove the Cancer (CheckMate 274)

Various Advanced Cancer

United States, Argentina, Australia, Austria, Belgium, Brazil, Canada, Chile, China, Colombia, Denmark, France, Germany, Greece, Ireland, Israel, Italy, Japan, Korea, Republic of, Mexico, Netherlands, Peru, Poland, Romania, Russian Federation and more
DEKK-TEC, Inc.
National Cancer Institute (NCI)

Completed

DM-CHOC-PEN Plus Radiation for Brain Tumors

Advanced Cancer

United States
Duke University
National Institute of Nursing Research (NINR); Palliative Care Research Cooperative...

Completed

Caregiver-Guided Pain Management Training in Palliative Care

Advanced Cancer

United States
University Hospital, Strasbourg, France

Unknown

Integration of Palliative Care in an Oncology and Hematology Unit

Advanced Cancer

France
Mirati Therapeutics Inc.

Approved for marketing

Expanded Access of Adagrasib (MRTX849) in Patients With Advanced Solid Tumors Who Have a KRAS G12C Mutation

Metastatic Cancer | Advanced Cancer | Malignant Neoplasm

United States
AstraZeneca

Completed

Investigating Safety, Tolerability and Efficacy of AZD5363 When Combined With Paclitaxel in Breast Cancer Patients (BEECH)

Advanced or Metastatic Breast Cancer | ER+ve Advanced or Metastatic Breast Cancer

Canada, France, Korea, Republic of, Czechia, Peru, United Kingdom, Spain, Japan, Mexico, Singapore, Bulgaria
Daiichi Sankyo, Inc.

Completed

Study to Assess the Safety and Tolerability of U3-1565 in Subjects With Advanced Solid Malignant Tumors

Advanced Solid Malignant Tumors | Advanced Ovarian Cancer

United States

Clinical Trials on Advanced Cancer Entities

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