Clinical Trials on Advanced+Cancer

Total 54636 results

OnKure, Inc.

Recruiting

First-in-Human Study of OKI-219 in Advanced Solid Tumors and Advanced Breast Cancer (PIKture-01)

Breast Cancer | Advanced Cancer

United States, Spain
University Medical Center Groningen

Completed

89Zr-AMG211 PET Imaging Study

Advanced Gastrointestinal Cancer

Netherlands
Sumitomo Pharma America, Inc.

Completed

A Study of BBI608 in Combination With Standard Chemotherapies in Adult Patients With Advanced Gastrointestinal Cancer

Advanced Gastrointestinal Cancer

United States, Canada
Benhealth Biopharmaceutical (Shenzhen) Co., Ltd.
Beijing 302 Hospital

Unknown

Study of Activated CIK Armed With Bispecific Antibody for Advanced Liver Cancer

Advanced Liver Cancer

China
Fuda Cancer Hospital, Guangzhou
Benhealth Biopharmaceutical (Shenzhen) Co., Ltd.

Withdrawn

Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Liver Cancer

Advanced Liver Cancer

China
Goethe University
Agaplesion Markus Krankenhaus gGmbH

Completed

Physical Function and Activities of Daily Living in Cancer Patients During Chemotherapy

Advanced Gastrointestinal Cancer

Germany
Tata Medical Center

Completed

Hypo-Fractionated Radiotherapy in Breast Cancer (HYPORT-B)

Breast Cancer | Advanced Breast Cancer | Metastatic Breast Cancer

India
Pfizer

Completed

Palbociclib in Real World Practice

Advanced Breast Cancer | Metastatic Breast Cancer

United States, Canada
University Hospital Tuebingen

Recruiting

Praegnant Breast Cancer: Early/Advanced/Metastatic (PRAEGNANT)

Advanced/Metastatic Breast Cancer | Breast Cancer (Early Breast Cancer)

Germany
Centre Georges Francois Leclerc

Completed

Preoperative Chemo-radiation With IG-IMRT Dose Escalation for Locally Advanced Rectal Cancers (RADICAL)

Advanced Rectal Cancers

France
University Health Network, Toronto

Recruiting

Umbrella Study for Single Patient Treatments in Oncology (UNIQUE)

Advanced Cancer | Rare Diseases

Canada
Eli Lilly and Company
Merck Sharp & Dohme LLC

Withdrawn

A Study of LY3200882 and Pembrolizumab in Participants With Advanced Cancer

Advanced Cancer

United States, Spain, France
Riboscience, LLC.
Oncobay Clinical, Inc

Recruiting

Evaluation of RBS2418 in Subjects With Advanced, Metastatic Solid Tumors

Advanced Cancer

United States
Bristol-Myers Squibb
Ono Pharmaceutical Co. Ltd

Active, not recruiting

A Study to Evaluate Efficacy in Subjects With Esophageal Cancer Treated With Nivolumab and Ipilimumab or Nivolumab Combined With Fluorouracil Plus Cisplatin Versus Fluorouracil Plus Cisplatin (CheckMate 648)

Various Advanced Cancer

United States, Japan, Argentina, Australia, Austria, Brazil, Canada, Chile, China, Colombia, Czechia, Denmark, France, Hong Kong, Italy, Korea, Republic of, Mexico, Peru, Poland, Portugal, Romania, Russian Federation, Singapore, Spain, ... and more
Pfizer

Recruiting

Study of PF-07248144 in Advanced or Metastatic Solid Tumors (KAT6)

Locally Advanced or Metastatic ER+ HER2- Breast Cancer | Locally Advanced or Metastatic Castration-resistant Prostate Cancer | Locally Advanced or Metastatic Non-small Cell Lung Cancer

United States, China, Australia, Korea, Republic of, Japan
AVEO Pharmaceuticals, Inc.

Completed

A Trial of Tivozanib (AV-951) in Combination With Capecitabine (Xeloda®) in Subjects With Advanced Solid Tumors

Advanced Solid Tumors | Locally Advanced or Metastatic Breast or Colorectal Cancer

United States
Abbisko Therapeutics Co, Ltd

Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-011 in Patients With Advanced Solid Tumor

Advanced Liver Cancer

China
Memorial Sloan Kettering Cancer Center

Completed

Person-Centered Oncology Care and Choices (P-COCC): Piloting and Initial Randomized Testing of a Combined Values Narrative Interview and Video Education Advance Care Planning Program in Gastrointestinal Oncology Patients

Advanced Gastrointestinal Cancer

United States
Guangxi Medical University

Unknown

Combined Immunotherapy and Targeted Therapy for Advanced Liver Cancer

Advanced Liver Cancer

China
Apceth GmbH & Co. KG

Terminated

Treatment of Advanced Gastrointestinal Cancer in a Phase I/II Trial With Modified Autologous MSC_apceth_101 (TREAT-ME 1)

Advanced Gastrointestinal Cancer

Germany
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

HCQ+ADC vs ADC in the Treatment of Advanced Breast Cancer

Advanced Breast Cancer | Metastatic Breast Cancer

China
Ahon Pharmaceutical Co., Ltd.

Recruiting

This is a Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of FCN-437c in Combination With Fluvestrant ± Goseraline Versus Placebo Combined With Fulvestrant ± Goserelin in Women With HR+ and HER2- Advanced Breast Cancer.

Advanced Breast Cancer | Female Breast Cancer

China
Ahon Pharmaceutical Co., Ltd.

Recruiting

This is a Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of FCN-437c Versus Placebo in Combination With Letrozole or Anastrozole ± Goserelin in Women With HR+ and HER2- Advanced Breast Cancer.

Advanced Breast Cancer | Female Breast Cancer

China
iTeos Belgium SA
GlaxoSmithKline; iTeos Therapeutics

Recruiting

Study of EOS-448 With Standard of Care and/or Investigational Therapies in Participants With Advanced Solid Tumors (TIG-006)

Melanoma | Head and Neck Cancer | Lung Cancer | Advanced Cancer

Spain, Italy, France, United States, United Kingdom, Belgium
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Recruiting

Study of SYSA1801 in the Treatment of Claudin( CLDN) 18.2 Positive Advanced Malignant Solid Tumor

Pancreatic Cancer | Advanced Solid Tumor | Gastric Cancer (GC) | Gastroesophageal Junction (GEJ) Cancer

China
Shanghai Miracogen Inc.

Recruiting

A Study of MRG002 in the Treatment of Patients With HER2-positive Unresectable Locally Advanced or Metastatic Breast Cancer

Advanced Breast Cancer | Metastatic Breast Cancer

China
Tianjin Medical University Cancer Institute and...
Jiangsu HengRui Medicine Co., Ltd.

Active, not recruiting

A Study of SHR6390 Combined With Famitinib in the Treatment of HR + / HER2- Advanced Breast Cancer.

Advanced Breast Cancer | Metastatic Breast Cancer

China
Onco Medical Consult GmbH
Eli Lilly and Company; Institut fuer Frauengesundheit

Unknown

Implementing Patients´ Competence in Oral Breast Cancer Therapy (IMPACT)

Advanced Breast Cancer | Metastatic Breast Cancer
AstraZeneca

Completed

A Clinical Trial to Compare Efficacy and Tolerability of Fulvestrant 250mg, 250mg Plus 250mg Loading Regimen and 500mg (FINDER II)

Advanced Breast Cancer | Metastatic Breast Cancer

Belgium, Turkey, Canada, Poland, Romania, Hungary, France, Czechia
Chang Gung Memorial Hospital
Eisai Co., Ltd.; Kaohsiung Breast Cancer Prevention and Education Society (KBCPES)

Unknown

Halaven Patient Registry (Metastatic Breast Cancer, MBC)

Advanced Breast Cancer | Metastatic Breast Cancer

Taiwan
Neovii Biotech

Terminated

Phase II Study With the Trifunctional Antibody Ertumaxomab to Treat Metastatic Breast Cancer Progressing After Endocrine Treatment

Advanced Breast Cancer | Metastatic Breast Cancer

Spain, Austria, France, Germany, Italy
Hoffmann-La Roche

Completed

A Study of Trastuzumab Emtansine in Indian Patients With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Unresectable Locally Advanced or Metastatic Breast Cancer Who Have Received Prior Treatment With Trastuzumab and a Taxane

HER2 Positive Breast Cancer, Metastatic Breast Cancer, Locally Advanced Breast Cancer

India
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Pembrolizumab and Cryoablation in People With Breast Cancer

Breast Cancer | Metastatic Breast Cancer | Triple Negative Breast Cancer | Triple Negative Breast Neoplasms | Breast Cancer Stage IV | Locally Advanced Breast Cancer | Metastatic Triple-Negative Breast Carcinoma | Locally Advanced Triple-Negative Breast Carcinoma

United States
Royal Marsden NHS Foundation Trust
Pfizer; Hoffmann-La Roche

Recruiting

Fulvestrant, Ipatasertib and CDK4/6 Inhibition in Metastatic ER+/HER2- Breast Cancer Patients Without ctDNA Suppression (FAIM)

Advanced Breast Cancer | Metastatic Breast Cancer | ER+ Breast Cancer

United Kingdom
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Patient-Reported Outcomes Version of Common Terminology Criteria (CTCPRO) Cognitive Debriefing

Hematologic Diseases | Solid Tumors | Advanced Cancers

United States
MapKure, LLC

Recruiting

A Study to Investigate BGB-3245 (Brimarafenib) With Panitumumab in Participants With Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers

Colorectal Cancer | Pancreatic Ductal Cancer | Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal Cancers

Australia, United States
Icahn School of Medicine at Mount Sinai

Terminated

Neoadjuvant Dose-Dense For Early Her2Neu Positive Breast Cancer

Locally Advanced Breast Cancer

United States
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of LEE011 in Postmenopausal Women With Advanced Breast Cancer.(MONALEESA-2) (MONALEESA-2)

Advanced, Metastatic Breast Cancer

United States, Canada, France, Italy, Spain, Taiwan, Hungary, Turkey, Belgium, Germany, Netherlands, Singapore, Austria, Czechia, Australia, Israel, Russian Federation, Sweden, United Kingdom, Korea, Republic of, Thailand, Lebanon, ... and more
Pfizer

Completed

Palbociclib Plus Letrozole For Postmenopausal Women With HR(+) HER2(-) Advanced Breast Cancer For Whom Letrozole Is Deemed Appropriate

Advanced Breast Cancer Female

Mexico, Argentina, Brazil, Colombia
Novartis Pharmaceuticals

Completed

Treatment of Locally Advanced Breast Cancer With Letrozole in Postmenopausal Women (PREDICT)

Locally Advanced Breast Cancer

Brazil
SMR Biotech Co., Ltd.

Terminated

A Study of the Efficacy and Safety of PerOx Quench on the Prevention of Oxaliplatin Treatment Induced Neuropathy

Colorectal Cancer | Neuropathy | Advanced Gastric Cancer

China
Pfizer

Completed

Study Of Sunitinib With Capecitabine In Breast Cancer

Advanced/Metastatic Breast Cancer

Japan
Olema Pharmaceuticals, Inc.
Novartis

Recruiting

Phase 1b Combo w/ Ribociclib and Alpelisib

Advanced Breast Cancer | Metastatic Breast Cancer | HR-positive Breast Cancer | HER2-negative Breast Cancer

United States, Australia
Carrick Therapeutics Limited
Pfizer

Recruiting

A Study of Samuraciclib in Combination With Fulvestrant in Metastatic or Locally Advanced Breast Cancer in Adult Participants (SUMIT-BC)

Breast Cancer | Metastatic Breast Cancer | Locally Advanced Breast Cancer

Spain, United States, Turkey, Hungary
SCRI Development Innovations, LLC
Daiichi Sankyo, Inc.

Recruiting

A Study of U3-1402 (Patritumab Deruxtecan) in Subjects With Metastatic Breast Cancer

Metastatic Breast Cancer | Locally Advanced Breast Cancer

United States
Consorzio Oncotech

Recruiting

Palbociclib Plus Fulvestrant in Women With Hormone Receptor Positive and Human Epidermal Growth Factor Receptor Type 2 Negative Locally Advanced or Metastatic Breast Cancer Previously Treated With a CDK4/6 Inhibitor in Combination With Hormonal Therapy

Metastatic Breast Cancer | Locally Advanced Breast Cancer

Italy
Rhizen Pharmaceuticals SA

Completed

Efficacy and Safety of Tenalisib (RP6530), a PI3K δ/γ and SIK3 Inhibitor, in Patients With Locally Advanced or Metastatic Breast Cancer

Metastatic Breast Cancer | Locally Advanced Breast Cancer

Georgia
Heidelberg University
Dafra Pharma; Hector-Stiftung; Monika-Kutzner Stiftung, Berlin, Germany; HEIFAN-Heidelberger...

Completed

Study of Artesunate in Metastatic Breast Cancer (ARTIC-M33/2)

Metastatic Breast Cancer | Locally Advanced Breast Cancer

Germany
AstraZeneca

Not yet recruiting

Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer (EvoPAR-BR01)

Advanced Breast Cancer

Canada
The First Affiliated Hospital with Nanjing Medical...
Zhejiang Cancer Hospital

Recruiting

Efficacy and Safety of Ribociclib in Combination With NSAI Versus Physician's Choice of Chemotherapy Sequential Endocrine Therapy in HR+/HER2- Advanced Breast Cancer

Advanced Breast Cancer

China

Clinical Trials on Advanced+Cancer

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