Clinical Trials on Advanced Cancers in Ireland

Total 1423 results

Roger Williams Medical Center
University of Colorado, Denver; Sorrento Therapeutics, Inc.

Completed

CAR-T Hepatic Artery Infusions or Pancreatic Venous Infusions for CEA-Expressing Liver Metastases or Pancreas Cancer (HITM-SURE)

Liver Metastases

United States
Fujirebio Diagnostics, Inc.

Completed

Risk of Ovarian Cancer in Patients With a Pelvic Mass

Ovarian Cancer

United States
Medical Research Council
European Organisation for Research and Treatment of Cancer - EORTC

Completed

Early Chemotherapy Based on CA 125 Level Alone Compared With Delayed Chemotherapy in Treating Patients With Recurrent Ovarian Epithelial , Fallopian Tube, or Primary Peritoneal Cancer

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cavity Cancer

Spain, Belgium, France, Netherlands, Austria, United Kingdom, Italy, South Africa, Portugal, Ireland
UNC Lineberger Comprehensive Cancer Center
Bayer

Completed

Regorafenib+FOLFIRI Versus Placebo+FOLFIRI as 2nd Line Tx in Metastatic Colorectal Cancer

Colorectal Cancer Metastatic

United States, Ireland
Brigham and Women's Hospital
CVS Caremark

Completed

Robust Evaluation to Measure Improvements in Nonadherence From Low-cost Devices (REMIND)

Depression | Epilepsy | Cardiovascular Disease | Diabetes | Breast Cancer | Parkinson's Disease | Mental Health Disorder | Prostatic Hypertrophy, Benign

United States
Allegro Diagnostics, Corp.
University of Missouri-Columbia; University of Pennsylvania; University of British... and other collaborators

Completed

Airway Epithelium Gene Expression in the Diagnosis of Lung Cancer: AEGIS CLIA (AEGIS)

Lung Cancer

United States, Canada, Ireland
Medtronic - MITG

Completed

The EMPrint™ Ablate and RESect Study in Patients With Metastatic Lung Tumors (EMPRESS) (EMPRESS)

Lung Cancer

United States, Germany
Advaxis, Inc.
Merck Sharp & Dohme LLC

Completed

ADXS31-142 Alone and in Combination With Pembrolizumab (MK-3475) in Participants With Previously Treated Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Cancer | Prostate Cancer

United States
Lawson Health Research Institute

Recruiting

Preservation of Swallowing in Respected Oral Cavity Squamous Cell Carcinoma: Examining Radiation Volume Effects (PRESERVE): A Randomized Trial

Head and Neck Cancer

Canada, United States, Ireland, United Kingdom
Gulam Manji
Merck Sharp & Dohme LLC

Completed

Perioperative Chemo and Pembrolizumab in Gastric Cancer

Gastric Cancer | Adenocarcinoma of the Gastroesophageal Junction

United States
Bristol-Myers Squibb

Active, not recruiting

A Study of Nivolumab Alone or Nivolumab Combination Therapy in Colon Cancer That Has Come Back or Has Spread (CheckMate142)

Microsatellite Stable Colorectal Cancer | Mismatch Repair Proficient Colorectal Cancer | Microsatellite Unstable Colorectal Cancer | Mismatch Repair Deficient Colorectal Cancer

United States, Australia, Belgium, Canada, Ireland, Italy, Spain, France
National Cancer Institute (NCI)

Recruiting

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

Stage IV Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Advanced Lung Non-Squamous Non-Small Cell Carcinoma | Metastatic Lung Non-Squamous Non-Small Cell Carcinoma | Recurrent Lung Non-Squamous Non-Small Cell Carcinoma

United States
Rahul Aggarwal
Novartis

Completed

LEE011 (Ribociclib) in Combination With Docetaxel Plus Prednisone in mCRPC

Prostate Cancer

United States
MacroGenics

Recruiting

A Study of Lorigerlimab With Docetaxel or Docetaxel Alone in Participants With Metastatic Castration-Resistant Prostate Cancer

Prostate Cancer Recurrent | Immunotherapy | Androgen-Independent Prostatic Cancer | Androgen-Resistant Prostatic Cancer | Hormone Refractory Prostatic Cancer | Immune Checkpoint Inhibitor | Androgen-Independent Prostatic Neoplasms | Androgen-Insensitive Prostatic Cance | Inhibitory Checkpoint Molecule

United States, Spain, France, Belgium, United Kingdom, Poland, Georgia, Bulgaria, Puerto Rico, Australia
University College, London

Recruiting

Add-Aspirin: A Trial Assessing the Effects of Aspirin on Disease Recurrence and Survival After Primary Therapy in Common Non Metastatic Solid Tumours

Cancer | Breast Cancer | Colorectal Cancer | Prostate Cancer | Gastro-oesophageal Cancer

Ireland, United Kingdom
National Cancer Institute (NCI)
NRG Oncology

Recruiting

Testing the Addition of Ipatasertib to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) for Stage III or IV Epithelial Ovarian Cancer

Ovarian Endometrioid Adenocarcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Fallopian Tube Endometrioid Adenocarcinoma | Ovarian High Grade Serous Adenocarcinoma | Fallopian Tube High Grade Serous Adenocarcinoma | Primary Peritoneal Endometrioid Adenocarcinoma | Stage III Fallopian... and other conditions

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Unknown

Cisplatin and Radiation Therapy Followed by Paclitaxel and Carboplatin in Treating Patients With Stage IB-IVA Cervical Cancer

Cervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Cervical Squamous Cell Carcinoma, Not Otherwise Specified | Stage IIA Cervical Cancer AJCC v7 | Stage IIB Cervical Cancer AJCC v6 and v7 | Stage IIIB Cervical Cancer AJCC v6 and v7 | Stage IVA Cervical Cancer AJCC v6 and v7 | Stage IIIA... and other conditions

United States
Celldex Therapeutics
Merck Sharp & Dohme LLC

Completed

A Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced Malignancies

Melanoma | Follicular Lymphoma | Renal Cell Carcinoma | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Pancreatic Adenocarcinoma | Ovarian Cancer | Fallopian Tube Cancer | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Lymphoplasmacytic Lymphoma | Non-Hodgkin Lymphoma | ... and other conditions

United States
Northwestern University

Completed

Intrathecal Trastuzumab for Leptomeningeal Metastases in HER2+ Breast Cancer

Breast Cancer

United States
Dana-Farber Cancer Institute
Pfizer

Active, not recruiting

Palbociclib and Endocrine Therapy for LObular Breast Cancer Preoperative Study (PELOPS)

Breast Cancer

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Capecitabine and Bevacizumab With or Without Atezolizumab in Treating Patients With Refractory Metastatic Colorectal Cancer

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Recurrent Colorectal Carcinoma | Metastatic Colorectal Carcinoma | Refractory Colorectal Carcinoma

United States
Xoft, Inc.

Completed

Feasibility Study Using the Xoft System for the Treatment of Endometrial Cancer

Endometrial Cancer

United States
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Plus Chemotherapy in Treating Patients With Advanced Colorectal Cancer That Overexpresses HER2

Colorectal Cancer

United States
Onxeo

Completed

A Study of Belinostat + Carboplatin or Paclitaxel or Both in Patients With Ovarian Cancer in Need of Relapse Treatment

Ovarian Cancer | Fallopian Tube Cancer | Bladder Cancer | Epithelial Ovarian Cancer

United States, Denmark, United Kingdom
Institute of Cancer Research, United Kingdom

Unknown

Intensity-Modulated Radiation Therapy in Treating Patients With Localized Prostate Cancer

Prostate Cancer

United Kingdom
Queen's Medical Center

Unknown

Aspirin and/or Folic Acid in Preventing Recurrent Colorectal Polyps

Colorectal Cancer

United Kingdom
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Atezolizumab Before and/or With Chemoradiotherapy in Immune System Activation in Patients With Node Positive Stage IB2, II, IIIB, or IVA Cervical Cancer

Cervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Cervical Squamous Cell Carcinoma | Stage IB2 Cervical Cancer AJCC v8 | Stage II Cervical Cancer AJCC v8 | Stage IIA Cervical Cancer AJCC v8 | Stage IIA1 Cervical Cancer AJCC v8 | Stage IIA2 Cervical Cancer AJCC v8 | Stage IIB Cervical Cancer... and other conditions

United States
IntuiTap Medical, Inc
ICON plc

Completed

A Study to Test Performance of Needle Placements for Neuraxial Procedures Using Tactile Imaging vs Control

Cancer | Central Nervous System Infections | Neurological Disorder | Pseudotumor Cerebri | Post-Dural Puncture Headache | Obstetric Procedure Pain | Orthopedic Procedure Pain

United States
AbbVie

Terminated

A Study Evaluating the Efficacy and Tolerability of Veliparib in Combination With Paclitaxel/Carboplatin-Based Chemoradiotherapy Followed by Veliparib and Paclitaxel/Carboplatin Consolidation in Adults With Stage III Non-Small Cell Lung Cancer (NSCLC)

Non-small Cell Lung Cancer Stage III

United States
Volastra Therapeutics, Inc.

Recruiting

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

Gastric Adenocarcinoma | Uterine Carcinosarcoma | Triple Negative Breast Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma | Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Transitional Cell Carcinoma of Bladder | Colorectal Adenocarcinoma | Gastroesophageal Junction... and other conditions

United States
NRG Oncology
National Cancer Institute (NCI)

Active, not recruiting

Ruxolitinib Phosphate, Paclitaxel, and Carboplatin in Treating Patients With Stage III-IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Ovarian Endometrioid Adenocarcinoma | Ovarian Clear Cell Adenocarcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Fallopian Tube Clear Cell Adenocarcinoma | Fallopian Tube Endometrioid Adenocarcinoma | Stage III Fallopian Tube Cancer AJCC v7 | Stage III Primary Peritoneal Cancer... and other conditions

United States
Movember Foundation
King's College London; Centre hospitalier de l'Université de Montréal (CHUM); University of California, San Francisco and other collaborators

Active, not recruiting

INTense ExeRcise for surviVAL Among Men With Metastatic Prostate Cancer (INTERVAL - GAP4) (INTERVAL)

Metastatic Prostate Cancer

United States, Australia, Netherlands, Canada, United Kingdom, Germany, Ireland
National Cancer Institute (NCI)
NRG Oncology

Completed

Chemoradiation Therapy and Ipilimumab in Treating Patients With Stages IB2-IIB or IIIB-IVA Cervical Cancer

Cervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Cervical Squamous Cell Carcinoma, Not Otherwise Specified | Stage IB2 Cervical Cancer AJCC v6 and v7 | Stage II Cervical Cancer AJCC v7 | Stage IIA Cervical Cancer AJCC v7 | Stage IIB Cervical Cancer AJCC v6 and v7 | Stage IIIB Cervical... and other conditions

United States
Mast Therapeutics, Inc.

Unknown

Phase III Randomized Study of 5-FU, CoFactor, and Avastin vs. 5-FU, LV and Avastin for First-Line Colorectal Cancer.

Metastatic Colorectal Cancer | Rectal Cancer | Colon Cancer

United States, Former Serbia and Montenegro
Dilon Medical Technologies Ltd.

Recruiting

MarginProbe 2.0 Data Collection Protocol

Breast Cancer

United States, Israel
Provista Diagnostics, Inc

Unknown

Breast Cancer Biomarker Sample Collection for the dtectDx Assay Verification

Breast Cancer

United States
American College of Radiology Imaging Network
National Cancer Institute (NCI)

Completed

Radiofrequency Ablation in Treating Patients With Bone Metastases (ACRIN-6661)

Pain | Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer

United States
AbbVie
IQVIA, formerly Quintiles

Completed

Open Label Continuation Treatment Study With Levodopa-Carbidopa Intestinal Gel in Advanced Parkinson's Disease

Advanced Parkinson's Disease

United Kingdom, Czechia, United States, Australia, Canada, Israel, New Zealand, Poland, Portugal, Russian Federation, Thailand
European Organisation for Research and Treatment...

Completed

Chemotherapy Followed by Surgery or Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer

Lung Cancer

United Kingdom, Belgium, Netherlands, Italy, France
NewLink Genetics Corporation

Terminated

A Study of CRLX101(NLG207) in Combination With Weekly Paclitaxel in Patients With Recurrent or Persistent Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Ovarian Cancer

United States
Jeffrey Zwicker, MD
National Heart, Lung, and Blood Institute (NHLBI); Quercegen Pharmaceuticals

Completed

Cancer Associated Thrombosis and Isoquercetin (CATIQ) (CATIQ)

Thromboembolism of Vein VTE in Colorectal Cancer | Thromboembolism of Vein in Pancreatic Cancer | Thromboembolism of Vein in Non-small Cell Lung Cancer

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Intraperitoneal Paclitaxel, Doxorubicin Hydrochloride, and Cisplatin in Treating Patients With Stage III-IV Endometrial Cancer

Recurrent Uterine Corpus Carcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Undifferentiated Carcinoma | Endometrial Adenosquamous Carcinoma | Endometrial Mixed Adenocarcinoma | Stage IIIA Uterine Corpus Cancer | Stage IIIC Uterine Corpus Cancer | Stage... and other conditions

United States
Queen Mary University of London

Completed

Anastrozole in Preventing Breast Cancer in Postmenopausal Women at Increased Risk of Breast Cancer (IBIS II)

Breast Cancer

Ireland, United Kingdom, Switzerland, Australia, Belgium, Chile, Denmark, Finland, Germany, Hungary, Italy, Malta, Portugal, Turkey
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Cetuximab, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer

Cervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Cervical Squamous Cell Carcinoma | Cervical Small Cell Carcinoma | Stage IB Cervical Cancer | Stage IIA Cervical Cancer | Stage IIB Cervical Cancer | Stage III Cervical Cancer | Stage IVA Cervical Cancer

United States
NCIC Clinical Trials Group

Completed

Exemestane in Reducing Breast Density in Postmenopausal Women at Risk for Breast Cancer

Breast Cancer

United States, Canada
National Cancer Institute (NCI)

Unknown

Disease-Specific Questionnaire in Assessing Quality of Life in Patients With Gastrointestinal-Related Neuroendocrine Tumors

Lung Cancer | Metastatic Cancer | Islet Cell Tumor | Gastrointestinal Carcinoid Tumor | Neoplastic Syndrome

Spain, United Kingdom, Germany, Netherlands, Israel, Sweden, Poland, Denmark, Greece, Italy
National Cancer Institute (NCI)

Completed

Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery

Stage III Soft Tissue Sarcoma AJCC v7 | Stage IV Soft Tissue Sarcoma AJCC v7 | Pleomorphic Liposarcoma | Metastatic Undifferentiated Pleomorphic Sarcoma | Metastatic Unresectable Sarcoma | Unresectable Soft Tissue Sarcoma | Metastatic Soft Tissue Sarcoma | Locally Advanced Soft Tissue Sarcoma | Metastatic... and other conditions

United States
AbbVie (prior sponsor, Abbott)
Quintiles, Inc.

Completed

Levodopa-Carbidopa Intestinal Gel Open-Label Study in Advanced Parkinson's Disease

Advanced Parkinson's Disease

United States, Australia, Canada, Czech Republic, Finland, Germany, Israel, Italy, Netherlands, New Zealand, Poland, Portugal, Russian Federation, Spain, Thailand, United Kingdom
Mayo Clinic
National Cancer Institute (NCI)

Completed

Percutaneous Cryoablation in Treating Patients With Painful Bone Metastases

Pain | Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer

United States
National Cancer Institute, Naples

Recruiting

Endometrial Cancer Conservative Treatment (E.C.Co). A Multicentre Archive

Endometrial Cancer

United States, Australia, Austria, Belgium, Canada, China, Denmark, France, Germany, Ireland, Italy, Japan, Korea, Republic of, Netherlands, Spain, United Kingdom

Clinical Trials on Advanced Cancers in Ireland

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CROs in Mali

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