Clinical Trials on Advanced PD-L1 Positive Malignancies
Total 574 results
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Sunesis PharmaceuticalsCompletedMyelodysplastic Syndromes | Leukemia, Lymphocytic, Acute | Leukemia, Myeloid, Chronic | Leukemia, Nonlymphocytic, AcuteUnited States
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Keio UniversityCompletedAcute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous LeukemiaJapan
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Janssen Research & Development, LLCCompletedNeoplasms | Neoplasms, Breast | Neoplasms, Ovarian | Advanced or Refractory Solid MalignanciesUnited States, United Kingdom, Spain, Belgium
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Naoyuki G. Saito, M.D., Ph.D.WithdrawnAcute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myeloid Leukemia | Acute Lymphocytic LeukemiaUnited States
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Dana-Farber Cancer InstituteBreast Cancer Research Foundation; Array BioPharmaCompletedAdvanced HER2-positive Breast Cancer | Brain Metastases From HER2 and Breast CancerUnited States
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MedSIRDaiichi Sankyo, Inc.CompletedAdvanced Breast Cancer | HER2-positive Breast Cancer | Brain Metastases | Leptomeningeal MetastasisSpain, Portugal
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City of Hope Medical CenterNational Cancer Institute (NCI)WithdrawnRecurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Acute Leukemia | Recurrent Acute Lymphoblastic Leukemia | Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Refractory Acute Lymphoblastic Leukemia | Systemic Mastocytosis | Recurrent Hematologic Malignancy | Hairy Cell Leukemia | Chronic... and other conditions
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Novartis PharmaceuticalsCompletedHypereosinophilic Syndrome | Chronic Myelogenous Leukemia | Systemic Mastocytosis | Acute Lymphoblastic Leukemia (Philadelphia Chromosome Positive)United States, Poland, Italy, Belgium, Canada, France, Australia, Netherlands, Sweden, Switzerland, United Kingdom, Spain, Korea, Republic of, Austria, Germany, Denmark, Finland, Singapore, Taiwan, Hong Kong, New Zealand, Norway
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Northwell HealthNew York Blood CenterCompletedHodgkin Lymphoma | Acute Lymphoblastic Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous LeukemiaUnited States
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Ann & Robert H Lurie Children's Hospital of ChicagoCompletedHematological Malignancies | Malignant Melanoma | Tumors | Leukemia, Lymphoblastic, Acute | Myelogenous Leukemia, ChronicUnited States
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Orca Biosystems, Inc.RecruitingAcute Myeloid Leukemia | Myelodysplastic Syndromes | Myelofibrosis | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia | Mixed Phenotype Acute LeukemiaUnited States
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Center for International Blood and Marrow Transplant...National Marrow Donor Program; Pediatric Blood and Marrow Transplant ConsortiumActive, not recruitingJuvenile Myelomonocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Myelodysplasia | Acute Lymphoblastic Leukemia/LymphomaUnited States
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Tragara Pharmaceuticals, Inc.CompletedMultiple Myeloma | AML | Blast Crisis | MDS | ALLUnited States
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St. Jude Children's Research HospitalAssisi FoundationCompletedNon-Hodgkin's Lymphoma | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Chronic Myelogenous LeukemiaUnited States
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University College, LondonBloodwiseCompletedHodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Myelodysplastic Syndrome | Acute Myeloid Leukaemia | Chronic Lymphocytic Leukaemia | Acute Lymphoblastic Leukaemia | Chronic Myeloid Leukaemia | Acquired Bone Marrow Failure Syndromes | Other Haematological Malignancies; Unrelated HSCT IndicatedUnited Kingdom
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Carey Anders, M.D.Seagen Inc.RecruitingAdvanced Breast Cancer | Brain Metastases | Human Epidermal Growth Factor 2 Positive Carcinoma of BreastUnited States
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Millennium Pharmaceuticals, Inc.CompletedAcute Myeloid Leukemia | Multiple Myeloma | Myelofibrosis | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Waldenstrom's Macroglobulinemia | Myelodysplastic Syndrome | Chronic Myelogenous Leukemia | Non-Hodgkins Lymphoma | Myeloid Metaplasia | Philadelphia Chromosome-negative CML | Advanced PolycythemiaUnited States
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National Cancer Institute (NCI)CompletedRecurrent Hodgkin Lymphoma | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Recurrent Non-Hodgkin Lymphoma | Recurrent Acute Lymphoblastic Leukemia | Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Recurrent Plasma Cell Myeloma | Myeloproliferative Neoplasm | Recurrent... and other conditionsUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingHematopoietic and Lymphoid Cell Neoplasm | Myelofibrosis | Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Secondary Acute Myeloid Leukemia | Recurrent Acute Myeloid Leukemia | Recurrent Chronic Myelomonocytic Leukemia | Refractory Chronic Myelomonocytic Leukemia | High Risk... and other conditionsUnited States
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St. Jude Children's Research HospitalCompletedAcute Lymphoblastic Leukemia | Chronic Myelocytic Leukemia | Myelodysplastic Syndrome | Acute Myelocytic Leukemia | Hodgkin's DiseaseUnited States
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Bristol-Myers SquibbWithdrawnMultiple Myeloma | Hodgkin Lymphoma | Non-Hodgkin's Lymphoma | Chronic Myelogenous Leukemia
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British Columbia Cancer AgencyBC Cancer FoundationCompletedGastrointestinal Stromal Tumors | Colorectal Cancer Metastatic | Advanced Melanoma | Advanced Non-Small Cell Lung Carcinoma | Patients With Diagnosed Malignancies Being Considered for Clinical TrialsCanada
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Millennium Pharmaceuticals, Inc.CompletedSmall Cell Lung Cancer | Non-Small Cell Lung Cancer | Metastatic Breast Cancer | Head and Neck Squamous Cell Carcinoma | Gastroesophageal Adenocarcinoma | Advanced Nonhematological MalignanciesUnited States
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Hyunseok Kang, MDNRG OncologyCompletedClinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IV Hypopharyngeal... and other conditionsUnited States
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AbbVie (prior sponsor, Abbott)CompletedAcute Lymphoblastic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | B-cell Chronic Lymphocytic Leukemia | MyelodysplasiaUnited States
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M.D. Anderson Cancer CenterIncyte CorporationCompletedAcute Myeloid Leukemia | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Chronic Myelogenous LeukemiaUnited States
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National Cancer Institute (NCI)RecruitingAnatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Pancreatic Carcinoma | Metastatic Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Castration-Resistant Prostate Carcinoma and other conditionsUnited States
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National Cancer Institute (NCI)RecruitingClinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IVA Lip and Oral... and other conditionsUnited States, Canada
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National Cancer Institute (NCI)RecruitingAnatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Stage III Uterine Corpus Cancer AJCC v8 | Stage IV Uterine Corpus Cancer AJCC v8 | Metastatic Malignant Solid Neoplasm | Clinical Stage... and other conditionsUnited States
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AstraZenecaCompletedAdvanced Solid Malignancies | Non-Small Cell Lung Cancer (NSCLC) | Metastatic Castrate-Resistant Prostate Carcinoma (mCRPC) | Colorectal Carcinoma (CRC)United States
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Fate TherapeuticsCompletedMelanoma | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Advanced Solid Tumors | HER2-positive Breast Cancer | Head and Neck Squamous Cell Carcinoma | HER2 Positive Gastric Cancer | EGFR Positive Solid TumorUnited States
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City of Hope Medical CenterNational Cancer Institute (NCI)Active, not recruitingRecurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Recurrent B Acute Lymphoblastic Leukemia | Refractory B Acute Lymphoblastic Leukemia | Recurrent Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Systemic Mastocytosis | Recurrent... and other conditionsUnited States
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Black Diamond Therapeutics, Inc.RecruitingNon-Small Cell Lung Cancer | NSCLC | Metastatic Lung Cancer | Metastatic Lung Non-Small Cell Carcinoma | EGF-R Positive Non-Small Cell Lung Cancer | Advanced Lung Carcinoma | EGFR-TKI Resistant Mutation | Advanced Non-Small Cell Squamous Lung Cancer | Epidermal Growth Factor Receptor C797S | Epidermal...United States
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Novartis PharmaceuticalsCompletedMetastatic Colorectal Cancer | Gastric Cancer | Advanced Solid Tumors | Metastatic Breast Cancer | Gastroesophageal Junction Cancer | Recurrent Glioblastoma Multiforme | Advanced Pancreatic Adenocarcinoma | Safety | Triple Negative Metastatic Breast Cancer | Dose Escalation | Preliminary Efficacy | Hormone Receptor...Canada, United Kingdom, Spain, Germany, Italy, Belgium, Australia, United States
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Mayo ClinicRecruitingClinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IVB Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Human Papillomavirus-Related Carcinoma | Locally Advanced Oropharyngeal CarcinomaUnited States
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Xencor, Inc.ICON Clinical ResearchCompletedAcute Myelogenous Leukemia | Blastic Plasmacytoid Dendritic Cell Neoplasm | B-cell Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia, Blast CrisisUnited States
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Medigene AGWithdrawnAcute Myeloid Leukemia | Myelodysplastic Syndromes | Myeloproliferative Disorders | Multiple Myeloma | Myelofibrosis | Chronic Myeloid Leukemia | Acute Lymphoid Leukemia | Malignant LymphomaNetherlands
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Singapore General HospitalNational Medical Research Council (NMRC), SingaporeCompletedAcute Myeloid Leukemia | Multiple Myeloma | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Non Hodgkin's Lymphoma | Hodgkin's DiseaseSingapore
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Otsuka Pharmaceutical Co., Ltd.CompletedAcute Myeloid Leukemia | Multiple Myeloma | Non-Hodgkin Lymphoma | Chronic Myeloid Leukemia | Acute Lymphoid LeukemiaJapan
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Fate TherapeuticsCompletedAcute Myeloid Leukemia | Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia | Chronic Myelogenous Leukemia | Hematologic Malignancies | Acute Graft-versus-host DiseaseUnited States
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Masonic Cancer Center, University of MinnesotaTerminatedMultiple Myeloma | AML | MDS | Non-hodgkin's Lymphoma | Leukemia, Lymphocytic, Acute | Hodgkin's Disease | Leukemia, Myeloid, Chronic | Leukemia, Lymphocytic, Chronic | JMMLUnited States
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University Health Network, TorontoThe Leukemia and Lymphoma SocietyCompletedAcute Myeloid Leukemia | Chronic Lymphocytic Leukemia | Acute Lymphocytic Leukemia | Hematologic Malignancy | Chronic Myelogenous Leukemia | Myelodysplasia | Hodgkin's DiseaseCanada
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National Cancer Institute (NCI)NRG OncologyRecruitingClinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IVA Lip and Oral... and other conditionsUnited States
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Orca Biosystems, Inc.Active, not recruitingAcute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myeloid Leukemia | Acute Leukemia | Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) | Acute Lymphoid LeukemiaUnited States
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Gamida Cell ltdActive, not recruitingLymphoma | Acute Leukemia | Hematological Malignancies | Acute Lymphoblastic Leukemia (ALL) | Myelodysplastic Syndrome (MDS) | Acute Myelogenous Leukemia (AML) | Chronic Myelogenous Leukemia (CML)Spain, United States, United Kingdom, Israel, Singapore, Brazil, Italy, France, Netherlands, Portugal
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St. Jude Children's Research HospitalAssisi FoundationTerminatedJuvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Chronic Myelocytic Leukemia | Myelodysplastic Syndrome | Acute Myelocytic Leukemia | Sarcoma, Myeloid | Hodgkin or Non-Hodgkin LymphomaUnited States
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Michael Morse, MDTerminatedAcute Lymphoblastic Leukemia (ALL) | Myelodysplastic Syndrome (MDS) | Acute Myelogenous Leukemia (AML) | B Cell Malignancies | Chronic Myelogenous Leukemia (CML)United States
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Foghorn Therapeutics Inc.RecruitingRefractory Acute Myeloid Leukemia | Refractory Chronic Myelomonocytic Leukemia | Relapsed Acute Myeloid Leukemia | Relapsed Myelodysplastic Syndromes | Refractory Myelodysplastic Syndromes | Advanced Hematologic Malignancy | Relapsed Chronic Myelomonocytic LeukemiaUnited States
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Novita Pharmaceuticals, Inc.Translational Drug DevelopmentCompletedBreast Cancer | Lung Cancer | Prostate Cancer | Colon Cancer | Pancreas Cancer | Liver Cancer | Ovary Cancer | Esophagus Cancer | Advanced or Metastatic Treatment-refractory Solid Tumor MalignanciesUnited States
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City of Hope Medical CenterNational Cancer Institute (NCI)WithdrawnAnatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 | Prognostic Stage IIIB Breast... and other conditions