Clinical Trials on Advanced Sarcoma

Total 8066 results

OHSU Knight Cancer Institute
Bayer; Oregon Health and Science University

Completed

Sorafenib Tosylate, Combination Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With High-Risk Stage IIB-IV Soft Tissue Sarcoma

Pleomorphic Rhabdomyosarcoma | Stage III Adult Soft Tissue Sarcoma AJCC v7 | Stage IV Adult Soft Tissue Sarcoma AJCC v7 | Stage IIB Adult Soft Tissue Sarcoma AJCC v7

United States
Yonsei University

Recruiting

Pemetrexed, Cisplatin With Soft Tissue Sarcoma (ALBATROSS)

Sarcoma,Soft Tissue

Korea, Republic of
Liaoning Tumor Hospital & Institute
China-Japan Friendship Hospital; First Hospital of China Medical University; Second... and other collaborators

Unknown

Anlotinib Hydrochloride Combined With Epirubicin and Ifosfamide for Soft Tissue Sarcoma Patients (ALTER-S005)

Sarcoma, Soft Tissue

China
National Cancer Institute (NCI)

Active, not recruiting

Testing the Combination of Belinostat and SGI-110 (Guadecitabine) or ASTX727 for the Treatment of Unresectable and Metastatic Conventional Chondrosarcoma

Metastatic Primary Central Chondrosarcoma | Unresectable Primary Central Chondrosarcoma | Locally Advanced Unresectable Primary Central Chondrosarcoma

United States
University of Colorado, Denver

Completed

Strategies to Improve Kaposi Sarcoma (KS) Outcomes in Zimbabwe (SIKO)

HIV | Kaposi Sarcoma (KS)

Zimbabwe
Mohammed Milhem, MBBS
University of Iowa; University of Iowa Adolescent and Young Adult (AYA) Cancer... and other collaborators

Terminated

Gemcitabine Plus Ascorbate for Sarcoma in Adults

Sarcoma | Soft Tissue Sarcoma | Bone Sarcoma | Metastatic Bone Tumor | Unresectable Soft Tissue Sarcoma

United States
Sheffield Teaching Hospitals NHS Foundation Trust
AstraZeneca; University of Sheffield; Cancer Research UK; University of Birmingham and other collaborators

Terminated

A Study of Selumetinib in Patients With Kaposi's Sarcoma (SCART)

AIDS-related Kaposi's Sarcoma

United Kingdom
National Cancer Institute (NCI)

Recruiting

Pomalidomide Treatment in Patients With Kaposi Sarcoma

Skin Kaposi Sarcoma

United States
Royal Marsden NHS Foundation Trust

Recruiting

Predicting Radiotherapy Response and Toxicities in Soft Tissue Sarcoma of the Extremities - Cohort B (PredicT-B)

Soft Tissue Sarcoma of the Extremities

United Kingdom
National Cancer Institute (NCI)

Completed

Sorafenib in Treating Patients With Soft Tissue Sarcomas (Extremity Sarcoma Closed to Entry as of 5/30/07)

Recurrent Osteosarcoma | Metastatic Osteosarcoma | Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Stage I Adult Soft Tissue Sarcoma | Stage II Adult Soft Tissue Sarcoma | Recurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Anti-cancer Drug, Rogaratinib (BAY 1163877), for Treatment of Advanced Sarcoma With Alteration in Fibroblast Growth Factor Receptor (FGFR 1-4), and in Patients With SDH-deficient Gastrointestinal Stromal Tumor (GIST)

Metastatic Gastrointestinal Stromal Tumor | Metastatic Sarcoma | Locally Advanced Sarcoma | Locally Advanced Gastrointestinal Stromal Tumor | Stage III Gastric and Omental Gastrointestinal Stromal Tumor AJCC v8 | Stage III Small Intestinal, Esophageal, Colorectal, Mesenteric, and Peritoneal... and other conditions

United States
Fred Hutchinson Cancer Center
Merck Sharp & Dohme LLC

Completed

Pembrolizumab and Radiation Therapy in Treating Patients With Intermediate or High-Grade Soft Tissue Sarcoma

Soft Tissue Sarcoma | Recurrent Soft Tissue Sarcoma

United States
Memorial Sloan Kettering Cancer Center
M.D. Anderson Cancer Center; Stanford University; Rockefeller University

Active, not recruiting

A Study of NKTR-214 in Combination With Nivolumab in Patients With Metastatic and/or Locally Advanced Sarcoma

SARCOMA

United States
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Preoperative Ultra-hypofractionated Radiotherapy Followed by Surgery for Retroperitoneal Sarcoma

Soft Tissue Sarcoma | Radiotherapy Side Effect | Retroperitoneal Sarcoma | Ultra-hypofractionated Radiotherapy | Stereotactic Ablative Radiotherapy

China
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

GISAR German Interdisciplinary Sarcoma Registry (GISAR)

Sarcoma | Carcinosarcoma | Sarcoma,Soft Tissue | Sarcoma of Bone

Germany
NantPharma, LLC

Terminated

QUILT-3.031: AMG 337 in Subjects With Advanced or Metastatic Clear Cell Sarcoma

Clear Cell Sarcoma

United States
University of California, San Francisco
Bristol-Myers Squibb; National Cancer Institute (NCI)

Completed

Intra-lesional Nivolumab Therapy for Limited Cutaneous Kaposi Sarcoma

HIV/AIDS | Kaposi Sarcoma | Immunosuppression

United States
Istituto Ortopedico Rizzoli

Completed

Chemotherapy-induced Necrosis in Ewing Sarcoma

Ewing Sarcoma of Bone

Italy
National Cancer Institute (NCI)

Terminated

A Phase II Trial of COL-3 in Patients With HIV Related Kaposi's Sarcoma

HIV Infection | AIDS-related Kaposi Sarcoma

United States
Genzyme, a Sanofi Company
Sanofi

Completed

A Combined Study in Pediatric Cancer Patients for Dose Ranging and Efficacy/Safety of Plerixafor Plus Standard Regimens for Mobilization Versus Standard Regimens Alone

Neuroblastoma | Brain Tumors | Ewing's Sarcoma/Soft Tissue Sarcoma

Belgium, Czechia, Denmark, France, Germany, Hungary, Israel, Italy, Netherlands, Poland, Spain, United Kingdom
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of LY2880070 and Gemcitabine in People With Ewing Sarcoma,Ewing-Like Sarcoma, and Desmoplastic Small Round Cell Tumor

Ewing Sarcoma | Ewing-Like Sarcoma

United States
National Cancer Institute (NCI)

Completed

Pomalidomide for Kaposi Sarcoma in People With or Without HIV

Sarcoma, Kaposi | Kaposi Sarcoma

United States
GlaxoSmithKline

Completed

A Pilot Study of Genetically Engineered NY-ESO-1 Specific NY-ESO-1ᶜ²⁵⁹T in HLA-A2+ Patients With Synovial Sarcoma (NY-ESO-1)

Neoplasms

United States
GlaxoSmithKline
Merck Sharp & Dohme LLC

Withdrawn

Clinical Trial of Safety, Tolerability and Antitumor Activity of Genetically Engineered T Cells in Combination With Anti-Cancer Agents in Relapsed and Refractory Synovial Sarcoma Expressing New York Esophageal Antigen-1 (NY-ESO-1) and/or LAGE-1a

Neoplasms
Birmingham Women's and Children's NHS Foundation...

Completed

Indo-cyanine Green (ICG) in Paediatric Oncology MIS

Rhabdomyosarcoma | Metastatic Osteosarcoma | Pulmonary Metastasis | Metastatic Ewing Sarcoma | Pediatric Renal Tumor | Non-Rhabdo. Soft Tissue Sarcoma

United Kingdom
Technical University of Munich

Unknown

Trabectedin and Irinotecan for Refractory Pediatric Sarcomas (TrIPReSarc)

Recurrent Ewing Sarcoma | Recurrent Rhabdomyosarcoma | Recurrent Childhood Soft Tissue Sarcoma
Ain Shams University

Active, not recruiting

Adjuvant Versus Neo-adjuvant Radiotherapy in Patients With Resectable Soft Tissue Sarcoma in Extremities : Wound Complications

Resectable Soft Tissue Sarcoma | Extremities | Radiotherapy Wound Complications

Egypt
Gynecologic Oncology Group
National Cancer Institute (NCI)

Terminated

Gemcitabine Hydrochloride and Docetaxel Followed by Doxorubicin Hydrochloride or Observation in Treating Patients With High-Risk Uterine Leiomyosarcoma Previously Removed by Surgery

Uterine Corpus Leiomyosarcoma | Stage I Uterine Sarcoma AJCC v7

United States, Belgium, France, Spain, United Kingdom, Netherlands, Norway, Venezuela
Mohammed Milhem, MBBS
University of Iowa

Recruiting

Gemcitabine Plus Ascorbate for Sarcoma in Adults (Pilot)

Sarcoma | Soft Tissue Sarcoma | Bone Sarcoma | Metastatic Bone Tumor | Unresectable Soft Tissue Sarcoma

United States
Children's Cancer Hospital Egypt 57357

Completed

Perioperative Use of Tranexamic (TXA) in Bone Tumor Surgery Will Change in Blood Loss and Transfusion Requirements.

Osteosarcoma | Ewing Sarcoma of Bone

Egypt
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Investigating Chemotherapy Treatments, Response and Subsets of HIV-associated Kaposi Sarcoma in Malawi

HIV | Kaposi Sarcoma

Malawi
Navidea Biopharmaceuticals
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

An Evaluation of Tc 99m Tilmanocept by Intravenous (IV) and Subcutaneous (SC) Injection in Kaposi Sarcoma (KS)

HIV Infections | Kaposi Sarcoma

United States
Istituto Superiore di Sanità

Completed

Treatment of Classical Non-HIV-Related Kaposi's Sarcoma With the Antiviral Drug Indinavir

Classical Kaposi's Sarcoma

Italy
Antonio Pérez Martínez

Recruiting

Clinical Trial of Infusion of Activated NK Cells for the Treatment of Sarcomas (SANKOMA)

Malignant Sarcoma

Spain
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Patient-Specific Computational Walking Models in Improving Surgical and Rehabilitation Treatment in Patients With Pelvic Sarcomas

Pelvic Sarcoma

United States
Fondazione IRCCS Istituto Nazionale dei Tumori,...
TransAtlantic Retroperitoneal Sarcoma Working Group

Recruiting

REtroperitoneal SArcoma Registry: an International Prospective Initiative (RESAR)

Retroperitoneal Sarcoma

United States, Italy, United Kingdom, Korea, Republic of, Slovenia, Australia, Canada, France, Germany, Poland, Spain
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Repeat or Single Quadratus Lumborum Block for the Reduction of Opioid Prescriptions After Surgery in Retroperitoneal Sarcoma Patients ("RESQU-SARC" Trial)

Retroperitoneal Sarcoma

United States
University Health Network, Toronto

Active, not recruiting

The PET- Retroperitoneal Sarcoma Study (PET-RPS)

Retroperitoneal Sarcoma

Canada
University of Michigan Rogel Cancer Center
AstraZeneca; Janssen Scientific Affairs, LLC

Active, not recruiting

Trabectedin in Combination With Olaparib in Advanced Unresectable or Metastatic Sarcoma

Sarcoma | Sarcoma Metastatic

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Robert L. Sloan Fund for Cancer Research

Withdrawn

Neoadjuvant Short-course Hypofractionated PBT for Non-metastatic RPS (PROTONS-RPS)

Retroperitoneal Sarcoma

United States
Massachusetts General Hospital
Dana-Farber Cancer Institute; PharmaMar

Completed

A Phase II Multi-Strata Study of PM01183 as a Single Agent or in Combination With Conventional Chemotherapy in Metastatic and/or Unresectable Sarcomas

Metastatic Sarcoma

United States
Novartis Pharmaceuticals

Completed

Treatment of Patients With RAD001 With Progressive Sarcoma

Progressive Sarcoma

Germany, Italy
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Studying Genes in Tissue Samples From Younger and Adolescent Patients With Soft Tissue Sarcomas

Chordoma | Desmoid Tumor | Recurrent Childhood Soft Tissue Sarcoma | Childhood Alveolar Soft-part Sarcoma | Childhood Angiosarcoma | Childhood Epithelioid Sarcoma | Childhood Fibrosarcoma | Childhood Leiomyosarcoma | Childhood Liposarcoma | Childhood Malignant Mesenchymoma | Childhood Neurofibrosarcoma | Childhood... and other conditions

United States
University of Washington
Eli Lilly and Company

Not yet recruiting

Evaluation of Abemaciclib and Radiation Therapy Before Surgery for the Treatment of High-Risk Adipocytic Retroperitoneal Sarcoma

Retroperitoneal Sarcoma

United States
Italian Sarcoma Group

Recruiting

Study on Clinical Features and Outcomes of Breast Sarcoma (Breast-Sarc)

Breast Sarcoma

Italy
Epizyme, Inc.
Analysis Group, Inc.

Completed

Epithelioid Sarcoma Natural History Study

Epithelioid Sarcoma

United States
University of California, San Francisco
Dana-Farber Cancer Institute; UCSF Benioff Children's Hospital Oakland; Alex's...

Completed

PAZIT Study for Children and Young Adults With Relapsed or Refractory Sarcoma

Sarcoma | Refractory Sarcoma

United States
King Faisal Specialist Hospital & Research Center

Unknown

Sarcoma Database at KFSH&RC

Sarcoma Database

Saudi Arabia
Immunolight, LLC

Recruiting

X-ray Psoralen Activated Cancer Therapy in Head and Neck, Breast, Sarcoma and Melanoma

Advanced Solid Tumor Cancer

United States
Novartis Pharmaceuticals

Completed

Medical Safety Follow-up Study for Patients Who Received More Than 28 Days of Total Exposure to BGG492

Adrenocortical Adenoma | Endometrial Stromal Sarcomas

Germany, United States, Korea, Republic of, Hungary, Italy, Slovakia

Clinical Trials on Advanced Sarcoma

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