Clinical Trials on Advanced Solid Tumors With MAPK Pathway Mutations
Total 2043 results
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D3 Bio (Wuxi) Co., LtdRecruitingAdvanced Solid Tumors With MAPK Pathway MutationsAustralia, China, United States
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Suzhou Genhouse Bio Co., Ltd.Shanghai East Hospital; Shandong Tumor HospitalRecruitingAdvanced Solid Tumors With MAPK Signal Pathway MutantChina
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Qilu Pharmaceutical Co., Ltd.RecruitingAdvanced Solid Tumors Harboring MAPK Pathway AlterationsChina
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Nested Therapeutics, IncRecruitingGlioma | Melanoma | NSCLC | Oncology | Solid Tumor, Adult | MEK Mutation | RAF Gene Mutation | Ras (KRAS or NRAS) Gene Mutation | MAPK Pathway Gene MutationAustralia
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Taiho Oncology, Inc.TerminatedAdvanced or Metastatic Solid Tumors Irrespective of Gene Alterations | Advanced or Metastatic Solid Tumors With Germline PTEN Inactivating MutationsUnited States, United Kingdom, Austria, France
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AmgenActive, not recruitingAdvanced/Metastatic Solid Tumors With KRAS p.G12C MutationTaiwan, Hong Kong
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Novartis PharmaceuticalsCompletedAdvanced Solid Tumors With Alterations of FGFR1, 2 and or 3 | Squamous Lung Cancer With FGFR1 Amplification | Bladder Cancer With FGFR3 Mutation or Fusion | Advanced Solid Tumors With FGFR1 Amplication | Advanced Solid Tumors With FGFR2 Amplication | Advanced Solid Tumors With FGFR3 MutationFrance, Spain, Taiwan, Germany, Netherlands, Singapore, United States, Australia, Korea, Republic of, Thailand, Israel, Italy, Turkey, Austria
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Turning Point Therapeutics, Inc.TerminatedAdvanced Solid Tumor | Metastatic Solid Tumor | KRAS Mutation-Related TumorsUnited States
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Incyte CorporationTerminatedAdvanced or Metastatic Solid Tumors | FGFR Mutations | FGFR TranslocationsUnited States
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Hubei Biological Medicine Industrial Technology...UnknownAdvanced Solid Tumors | HRD | BRCA MutationChina
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Frontier Medicines CorporationRecruitingColorectal Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Metastatic Solid Tumor | Solid Tumor, Adult | Unresectable Solid Tumor | KRAS G12C | Advanced Solid Tumors With KRAS G12C MutationsUnited States
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Novartis PharmaceuticalsRecruitingContinued Access to Study Treatment(s), Cancers With a Mass, Bulky Tumor, Nodule, Lump, Advanced Cancer, Advanced Solid Tumors, Advanced Solid MalignanciesSpain, Taiwan, United States, Singapore, France
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Faeth TherapeuticsActive, not recruitingAdvanced Solid Tumor | PIK3CA Mutation | PTEN Loss of Function MutationUnited States
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Cancer Institute and Hospital, Chinese Academy...RecruitingPatients With Advanced Solid TumorsChina
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Beijing InnoCare Pharma Tech Co., Ltd.Not yet recruitingPatients With Advanced Solid TumorsChina
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Bio-Thera SolutionsGeorge Clinical Pty LtdActive, not recruiting
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Beijing InnoCare Pharma Tech Co., Ltd.Recruiting
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Shanghai Junshi Bioscience Co., Ltd.RecruitingPatients With Advanced Solid TumorsChina
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Gustave Roussy, Cancer Campus, Grand ParisRecruiting
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Beijing Tide Pharmaceutical Co., LtdRecruitingPatients With Advanced Solid TumorsChina
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PharmaMarRecruitingPatients With Advanced Solid TumorsSpain
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Shanghai Changzheng HospitalNot yet recruitingAdvanced Solid Tumors With Neuroendocrine Differentiation
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Sichuan Kelun Pharmaceutical Research Institute...RecruitingSelected Subjects With Advanced Solid TumorsChina
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Tianjin Hemay Oncology Pharmaceutical Co., LtdRecruitingPatients With Advanced Stage Solid TumorsChina
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Georgetown UniversityImmune System Key LtdRecruitingSolid Tumor | KRAS Mutation-Related TumorsUnited States
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Gustave Roussy, Cancer Campus, Grand ParisUnknownPatients With Advanced or Metastatic Solid TumorsFrance
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Suzhou Zelgen Biopharmaceuticals Co.,LtdRecruitingSolid Tumor | KRAS Mutation-Related TumorsChina
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Suzhou Genhouse Bio Co., Ltd.Not yet recruitingPatient With Advanced Solid TumorChina
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BeBetter Med IncXiangya Hospital of Central South UniversityRecruitingAdvanced or Metastatic Solid Tumor | KRAS G12C MutationChina
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Disphar International B.V.CompletedPatients With Advanced or Metastatic Solid Tumors
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Taiho Oncology, Inc.TerminatedAdvanced Solid Tumors With HER2 Abnormalities | Advanced Solid Tumors With HER3 AbnormalitiesUnited States, Spain, France, United Kingdom
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MapKure, LLCRecruitingSolid Tumor | B-Raf Mutation-Related TumorsUnited States, Australia
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Fujian Cosunter Pharmaceutical Co. LtdUnknownSolid Tumor | C-Met Mutation-Related TumorsChina
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IconOVir BioRecruitingPatients With Advanced Solid TumorsUnited States
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AstraZenecaDaiichi Sankyo Co., Ltd.Active, not recruitingAdvanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,BreastItaly, Spain, United States, France, Korea, Republic of, Japan, Canada, Denmark, Belgium
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BeiGeneCompletedFor Participants With Advanced Solid Tumors Failed With Previous Lines of TreatmentAustralia
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Deciphera Pharmaceuticals LLCTerminatedMetastatic Solid Tumors | Locally Advanced Tumors | Cancers With MET Genomic Alterations | Cancers With TRK Genomic AlterationsUnited States
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Pasithea Therapeutics Corp.RecruitingAdvanced Solid Tumors | RAS Mutation | NF1 Mutation | RAF MutationUnited States
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AnHeart Therapeutics Inc.RecruitingIDH1 Inhibitor AB-218 in Patients With Advanced IDH1 Mutant Cholangiocarcinoma and Other Solid TumorCholangiocarcinoma With IDH1 Mutation | Solid Tumors With IDH1 MutationChina
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AstraZenecaCompletedAdvanced Solid Tumours With Androgen Receptor Pathway as a Potential FactorUnited Kingdom, United States
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Jiangsu Simcere Pharmaceutical Co., Ltd.RecruitingAdvanced or Metastatic Solid Tumors With NTRK, ROS1 or ALK Gene FusionChina
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BioMed Valley Discoveries, IncTerminatedAdvanced Solid Tumor | MAP2K1 Gene Mutation | BRAF Gene Mutation | MEK Mutation | BRAF Gene Alteration | MEK Alteration | MAP2K1 Gene Alteration | MAP2K2 Gene Mutation | MAP2K2 Gene AlterationUnited States
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Memorial Sloan Kettering Cancer CenterRecruitingSolid Tumor | Neuroblastoma | Solid Tumor, Adult | Primary Brain Tumor | Solid Carcinoma | Low-grade Glioma | Central Nervous System Tumor | Refractory Cancer | CNS Tumor, Adult | CNS Tumors | NF1 | Plexiform Neurofibroma | CNS Tumor, Childhood | Optic Pathway Gliomas | MAP Kinase Family Gene MutationUnited States
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AmgenCompletedCancer | Advanced Solid Tumors | Solid Tumors | Tumors | Advanced MalignancyUnited States, Australia
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NantCell, Inc.CompletedQUILT-2.016: Study of AMG 479 With Biologics or Chemotherapy for Subjects With Advanced Solid TumorsCancer | Advanced Solid Tumors | Solid Tumors | Tumors | Advanced Malignancy
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Boehringer IngelheimCompletedSolid Tumors, KRAS MutationJapan
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Boehringer IngelheimActive, not recruitingSolid Tumors, KRAS MutationSpain, United Kingdom, United States, Belgium
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Incyte CorporationRecruitingA Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid TumorsAdvanced Solid Tumors | Solid Tumors | Metastatic Solid TumorsUnited States, Spain, United Kingdom, France, Italy, Denmark, Switzerland
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Hoffmann-La RocheCompletedSolid Tumors, Advanced Solid TumorsUnited States
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Esperance Pharmaceuticals IncCompletedAdvanced Solid Tumors | Solid TumorsUnited States