Search clinical trials for: Sitaxentan sodium

Total 10398 results

Pfizer

Terminated

A Non-Interventional, Patient Registry For The Collection Of Pre-Defined Safety Data In Patients Prescribed Thelin (PROSE)

Pulmonary Arterial Hypertension

Belgium, Germany, France
Pfizer

Completed

Pilot Chart Review Study Of Sitaxentan Sodium (Thelin) In Patients With Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension
Pfizer

Completed

Phase 1, Single and Multiple Doses Study of Sitaxentan in Japanese and Western Subjects

Healthy

United States
Pfizer

Terminated

Long-Term Open-Label, Safety Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension Patients

Hypertension, Pulmonary

Japan
Pfizer

Terminated

A 12 Week Safety And Efficacy Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension Patients

Hypertension, Pulmonary

Japan
Pfizer

Terminated

A Long-Term, Open-Label Study to Evaluate the Safety of Sitaxsentan Sodium Treatment in Patients With Pulmonary Arterial Hypertension (STRIDE-3)

Pulmonary Arterial Hypertension

United States, Netherlands, Canada, Belgium, France, Germany, Italy, Spain, United Kingdom, Australia, Poland, Austria, Brazil, Israel, Argentina, Mexico
Institut National de la Santé Et de la Recherche...

Terminated

Study on the Effects of Sitaxsentan on Airway Remodeling in Patients With Severe Asthma (Sitax)

Effect of Sitaxsentan on Airway Remodeling in Severe Asthma

France
VA Office of Research and Development
Medical University of South Carolina

Completed

Proteolytic Enzyme Induction Within the Human Myocardial Interstitium

Heart Disease

United States
ICOS-Texas Biotechnology
ICOS Corporation; Texas Biotechnology Corporation

Unknown

Safety and Efficacy of Sitaxsentan in the Treatment of Pulmonary Arterial Hypertension

Pulmonary Hypertension

United States, Canada
Encysive Pharmaceuticals

Completed

Safety and Efficacy Study of Sitaxentan Sodium (Thelin™) in Patients With Pulmonary Arterial Hypertension

Pulmonary Hypertension

United States
Pfizer

Terminated

A Pharmacokinetic Drug-Drug Interaction (DDI) Study Between Sitaxsentan And Sildenafil, And Between Sitaxsentan And Tadalafil After Multiple Doses

Pulmonary Arterial Hypertension

Singapore
Pfizer

Completed

Confirming The Sitaxsentan Dose In Patients Undergoing Heart Surgery (FCAD02)

Cardiac Surgery Subjects | Subjects Undergoing CABG and/or Cardiac Valve Replacement

United States
Pfizer

Withdrawn

Drug Interaction Between Ritonavir And Sitaxsentan

Pulmonary Arterial Hypertension
Pfizer

Terminated

Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil (SR-PAAS)

Pulmonary Arterial Hypertension | Pulmonary Hypertension

United States, Bulgaria, Argentina, Chile, China, Colombia, Costa Rica, Czech Republic, Dominican Republic, Guatemala, India, Malaysia, Mexico, Peru, Philippines, Romania, Russian Federation, Saudi Arabia, Serbia, Slovakia, South... and more
Pfizer

Terminated

Study Providing Monotherapy (Sitaxsentan) And Combination Therapy (Sitaxsentan+Sildenafil) To Subjects With Pulmonary Arterial Hypertension (PAH) To Assess Long-Term Safety

Pulmonary Arterial Hypertension | Pulmonary Hypertension

United States, Romania, Ukraine
University of Delaware

Completed

Adverse Neurogenic Actions of Dietary Salt

Blood Pressure

United States
Pfizer

Terminated

Study Looking at Combination Therapy (Sitaxsentan+Sildenafil) Vs. Monotherapy (Sitaxsentan Alone) SR-PAAS -Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil

Pulmonary Arterial Hypertension | Pulmonary Hypertension

United States, Bulgaria, Argentina, Chile, China, Colombia, Czech Republic, India, Malaysia, Mexico, Peru, Romania, Russian Federation, Serbia, South Africa, Thailand, Turkey, Ukraine
Aga Khan University
Zeenat Qureshi Stroke Institute

Recruiting

Best Solution Identification to Prevent Hyperchloremia Combinations of Sodium Chloride and Sodium Acetate IV Fluids Along With Standard of Care Treatment in Acute Stroke Patients (sodium acetate)

Stroke, Acute

Pakistan
West Penn Allegheny Health System
Johns Hopkins University; University of Colorado, Denver; Massachusetts General... and other collaborators

Withdrawn

Pharmacogenomics in Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension | Pulmonary Hypertension | PAH WHO Group I

United States
University of Edinburgh
Encysive Pharmaceuticals

Completed

Role of Endothelin-A (ETA) and Endothelin-B (ETB) Receptors in the Vasodilatory Response to Endothelin-3 (ET-3)

Pulmonary Arterial Hypertension | Vasodilation | Vasoconstriction

United Kingdom
Rigel Pharmaceuticals

Completed

Efficacy and Safety Study of Fostamatinib Disodium Tablets to Treat T-Cell Lymphoma

T Cell Lymphoma

United States, Canada
Pfizer

Withdrawn

Effect Of Rifampin On Pharmacokinetics Of Sitaxsentan

Pulmonary Arterial Hypertension
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy

Sarcoma | Ovarian Cancer | Brain Tumor | Ototoxicity | Neuroblastoma | Liver Cancer | Central Nervous System Tumor | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

Canada, United States, Australia
University of Delaware

Completed

Effects of Acute Dietary Sodium on Cerebrovascular Reactivity and Blood Pressure Reactivity

Blood Pressure | Cerebrovascular Reactivity

United States
Institut d'Anesthesiologie des Alpes Maritimes
Université de Nice Sophia Antipolis; Medical University of Grenoble

Completed

Preventive Sodium Lactate and Traumatic Brain Injury

Head Trauma

France
Radboud University Medical Center

Unknown

The Effect Lactate Administration on Cerebral Blood Flow During Hypoglycemia

Type1diabetes | Hypoglycemia Unawareness

Netherlands
McGill University

Completed

Impact of NaHCO3- on Exercise Hyperpnea

Pulmonary Ventilation

Canada
Austin Health

Completed

Bicarbonate and Lipocalin in Systemic Inflammatory Response Syndrome (SIRS) Study (BLISS)

Systemic Inflammatory Response Syndrome | Renal Impairment | Oliguria

Australia
Medical University of Graz

Completed

Blood Gas Analysis and Buffering In Cardiac Arrest (BABICA)

Cardiac Arrest

Austria
Brigham and Women's Hospital

Completed

Dietary Salt Intake and Vascular Function

Healthy

United States
Osaka General Medical Center

Completed

Prevention of Contrast-Induced Nephropathy With Sodium Bicarbonate Bolus Injection

Emergent Coronary Procedure

Japan
Lars Wiuff Andersen
University of Aarhus

Recruiting

Bicarbonate for In-Hospital Cardiac Arrest (BIHCA)

Cardiac Arrest

Denmark
Gladwin, Mark, MD

Completed

Oral Nitrite in Adults With Metabolic Syndrome and Hypertension (ONTX)

Hypertension | Metabolic Syndrome

United States
Azienda Sanitaria ASL Avellino 2

Unknown

Effects of Short-chain Fatty Acids on Inflammatory and Metabolic Parameters in Maintenance Hemodialysis (PLAN)

Endstage Renal Disease
University Hospital Birmingham NHS Foundation Trust

Unknown

Nitrite Mediated Cardioprotection During Coronary Artery Bypass Surgery

Coronary Artery Bypass Surgery

United Kingdom
Erasmus Medical Center

Completed

The Effect of Correction of Metabolic Acidosis in CKD on Intrarenal RAS Activity (BIC)

Chronic Kidney Disease

Netherlands
Capital Medical University
Beijing Friendship Hospital; Cancer Institute and Hospital, Chinese Academy...

Unknown

Dietary Nitrate on Salivary Flow for Nasopharyngeal Carcinoma Patients

Nasopharyngeal Carcinoma

China
Karolinska Institutet

Completed

Coronary Artery Bypass and Nitrate Oral Supplementation (CABANOS)

Coronary Artery Disease

Sweden
National Cancer Institute (NCI)

Recruiting

Radium-223 in Biochemically Recurrent Prostate Cancer

Biochemical Recurrent Prostate Cancer

United States
Pharma VAM

Unknown

Clinical Study in the Treatment of Patients With COVID-19

COVID-19

Russian Federation
Tabriz University of Medical Sciences

Not yet recruiting

Evaluation of the Safety and Efficacy of Sodium Pentaborate Pentahydrate in Patients With Advanced Renal Cell Carcinoma

Renal Cell Carcinoma

Iran, Islamic Republic of
Shandong University

Unknown

Lower Fluorescein Sodium Dose on Confocal Laser Endoscopy Image Quality and Yellow Discoloration of the Skin

Image Quality | Skin Discoloration

China
Texas State University

Recruiting

A Comparison of Sodium-Induced Responses by Sex

Endothelial Dysfunction | Sodium Intake

United States
Medical College of Wisconsin

Recruiting

Renal Metabolism in Salt-sensitive Human Blood Pressure

Hypertension

United States
Imperial College London

Completed

Propionate and Energy Homeostasis (PROEM)

Obesity

United Kingdom
University of Sao Paulo
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.; Fundação de Apoio...

Completed

Dietary Sodium Intake in Acute Heart Failure (SODIC)

Heart Failure; With Decompensation | Heart Failure，Congestive

Brazil
Maastricht University Medical Center

Completed

Aldosterone, Microvascular Function and Salt-sensitivity

Hypertension | Metabolic Syndrome | Insulin Resistance | Abdominal Obesity | Sodium-sensitivity

Netherlands
DongGuk University
Boryung Pharmaceutical Co., Ltd

Completed

Effect of High- and Low-sodium Intake on the Pharmacokinetics and Pharmacodynamic Effects of Fimasartan

Hypertension

Korea, Republic of
Erling Bjerregaard Pedersen

Unknown

The Effect of Sodium Nitrite on Renal Function and Blood Pressure in Hypertensive Versus Healthy Subjects (HYCA)

Hypertension

Denmark
McGill University Health Centre/Research Institute...

Unknown

Preventing Acute Renal Failure After Cardiac Surgery in High Risk Patients Using Sodium Bicarbonate Therapy (PARACHUTE)

Kidney Failure, Acute

Canada

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