Clinical Trials on Adverse Effects

Total 5788 results

  • Sequenom, Inc.
    Completed
    Non-Invasive Screening for Fetal Aneuploidy: A New Maternal Plasma Marker
    Turner Syndrome | Down Syndrome (Trisomy 21) | Patau Syndrome (Trisomy 13) | Edwards Syndrome (Trisomy 18)
    United States
  • Progenity, Inc.
    Unknown
    Whole Blood Specimen Collection From Pregnant Subjects
    Down Syndrome | DiGeorge Syndrome | Turner Syndrome | Klinefelter Syndrome | Edwards Syndrome | Patau Syndrome | Perinatal Infections
    United States
  • University of Michigan
    National Institute on Disability, Independent Living, and Rehabilitation...
    Completed
    Clinical Trial of a Serious Game for Individuals With SCI/D
    Spinal Cord Diseases | Spinal Stenosis | Spinal Cord Injury | Spina Bifida | Syringomyelia | Spinal Neoplasms | Transverse Myelitis | Spinal Cord Involvement | Polio and Post-polio Syndrome
    United States
  • Arkansas Colleges of Health Education
    Recruiting
    High Intensity Functional Training for Individuals With Neurologic Diagnoses and Their Care Partners (SHIFT-AR)
    Stroke | Multiple Sclerosis | Brain Injuries | Parkinson Disease | Spinal Cord Injuries | Neurologic Disorder | Poliomyelitis | Spina Bifida
    United States
  • Chang Gung Memorial Hospital
    Enrolling by invitation
    A Study to Evaluate Accuracy and Validity of the Chang Gung ECG Abnormality Detection Software
    Myocardial Infarction | Left Bundle-Branch Block | Atrial Flutter | Left Ventricular Hypertrophy | Long QT Syndrome | Sinus Bradycardia | Right Bundle-Branch Block | Sinus Tachycardia | Premature Atrial Complexes | Premature Ventricular Complexes
    Taiwan
  • Istanbul University - Cerrahpasa (IUC)
    Not yet recruiting
    A New Approach in Intensive Care Unit Consciousness Assessment: FIVE Score
    Unconsciousness | Traumatic Brain Injury | Subarachnoid Hemorrhage | Coma | Infratentorial Neoplasms | Epilepsy, Temporal Lobe | Assessment, Self | Intensive Care Neurological Disorder | Arnold Chiari Malformation | Cerebrovascular Event | Postoperative Intracranial Hematoma | Postoperative Intracranial Haemorrhage and other conditions
    Turkey
  • University of Colorado, Denver
    Completed
    Micro RNAs as a Marker of Aortic Aneurysm in Hereditary Aortopathy Syndromes
    Marfan Syndrome | Turner Syndrome | Loeys-Dietz Syndrome | Thoracic Aortic Aneurysm and Dissection Syndromes | Ehlers-Danlos Type IV Syndrome
    United States
  • Lenetix Medical Screening Laboratory
    Unknown
    Non-Invasive Determination of Fetal Chromosome Abnormalities
    Down Syndrome (Trisomy 21) | Edward's Syndrome (Trisomy 18) | Patau Syndrome (Trisomy 13) | Klinefelter Syndrome (47, XXY) | and Other Chromosome | Abnormalities.
    United States
  • National Institute of Neurological Disorders and...
    Baylor College of Medicine
    Completed
    Study of Phenotype and Genotype Correlations in Patients With Contiguous Gene Deletion Syndromes
    Prader-Willi Syndrome | DiGeorge Syndrome | Williams Syndrome | Angelman Syndrome | Smith-Magenis Syndrome | Chromosome Abnormalities | Shprintzen Syndrome
    United States
  • Jerry Vockley, MD, PhD
    Ultragenyx Pharmaceutical Inc
    No longer available
    Compassionate Use of Triheptanoin (C7) for Inherited Disorders of Energy Metabolism
    Barth Syndrome | Mitochondrial Trifunctional Protein Deficiency | Very Long-chain acylCoA Dehydrogenase (VLCAD) Deficiency | Carnitine Palmitoyltransferase Deficiencies (CPT1, CPT2) | Long-chain Hydroxyacyl-CoA Dehydrogenase Deficiency | Glycogen Storage Disorders | Pyruvate Carboxylase Deficiency... and other conditions
    United States
  • Progenity, Inc.
    Completed
    Expanded Noninvasive Genomic Medical Assessment: The Enigma Study
    Down Syndrome | Aneuploidy | DiGeorge Syndrome | Turner Syndrome | Klinefelter Syndrome | Chromosome Deletion | Edwards Syndrome | Patau Syndrome
    United States
  • National Institute of Diabetes and Digestive and...
    Recruiting
    Natural History of Noncirrhotic Portal Hypertension
    Cystic Fibrosis | Turner Syndrome | Congenital Hepatic Fibrosis | Immunologic Deficiency Syndrome | Idiopathic Non-Cirrhotic Portal Hypertension
    United States
  • Eunice Kennedy Shriver National Institute of Child...
    Recruiting
    Gonadal Tissue Freezing for Fertility Preservation in Individuals at Risk for Ovarian Dysfunction, Premature Ovarian Insufficiency and Clinically Indicated Gonadectomy
    Turner Syndrome | Galactosemia | Ovarian Disfunction | Post-menarcheal Adolescents | Variations in Sex Characteristics | Differences in Sex Development
    United States
  • Johns Hopkins University
    National Heart, Lung, and Blood Institute (NHLBI)
    Enrolling by invitation
    Derivation of Human Induced Pluripotent Stem (iPS) Cells to Heritable Cardiac Arrhythmias
    Hypertrophic Cardiomyopathy (HCM) | Long QT Syndrome (LQTS) | Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) | Inherited Cardiac Arrythmias | Brugada Syndrome (BrS) | Early Repolarization Syndrome (ERS) | Arrhythmogenic Cardiomyopathy (AC, ARVD/C) | Dilated Cardiomyopathy (DCM) | Muscular... and other conditions
    United States
  • Natera, Inc.
    Children's Hospital of Philadelphia; Montefiore Medical Center; University of... and other collaborators
    Completed
    SNP-based Microdeletion and Aneuploidy RegisTry (SMART) (SMART)
    Prader-Willi Syndrome | DiGeorge Syndrome | 22q11 Deletion Syndrome | Angelman Syndrome | Trisomy 21 | Trisomy 18 | Trisomy 13 | Monosomy X | Sex Chromosome Abnormalities | 1p36 Deletion Syndrome | Cri-du-Chat Syndrome
    United States, Australia, Ireland, Spain, Sweden, United Kingdom
  • Children's Hospital Medical Center, Cincinnati
    Recruiting
    RASopathy Biorepository
    Neurofibromatosis 1 | Noonan Syndrome | Legius Syndrome | Cardiofaciocutaneous Syndrome | Costello Syndrome | SYNGAP1-Related Intellectual Disability | DLG4 | RAS Mutation | Noonan Syndrome With Multiple Lentigines | Noonan Neurofibromatosis Syndrome | Smith-Kingsmore Syndrome | MTOR Gene Mutation | GATOR-1 Gene... and other conditions
    United States
  • dr. Laura C. G. de Graaff-Herder
    Not yet recruiting
    Growing up With the Young Endocrine Support System (YESS!) (YESS)
    Congenital Adrenal Hyperplasia | Hypogonadotropic Hypogonadism | Growth Hormone Deficiency | Turner Syndrome | Addison's Disease | Klinefelter Syndrome | Combined Pituitary Hormone Deficiency | Androgen Insensitivity Syndrome | Thyroid Dysgenesis
    Spain, United Kingdom, Belgium, Netherlands
  • Protecting Brains Saving Futures
    Not yet recruiting
    Protecting Brains and Saving Futures - the PBSF Protocol (PBSF)
    Brain Injuries | Intraventricular Hemorrhage | Congenital Heart Disease | Hypoxic-Ischemic Encephalopathy | Newborn Morbidity | Inborn Errors of Metabolism | Extracorporeal Membrane Oxygenation Complication | Respiratory Complication | Hemodynamic Instability | Nosocomial Infection | Neonatal Seizure | Brain... and other conditions
    Brazil
  • Novo Nordisk A/S
    Completed
    Observational Prospective Study on Patients Treated With Norditropin®
    Chronic Kidney Disease | Turner Syndrome | Noonan Syndrome | Chronic Renal Insufficiency | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Adult Growth Hormone Deficiency | Genetic Disorder | Foetal Growth Problem | Small for Gestational Age
    Israel, Saudi Arabia, Spain, Argentina, Russian Federation, Germany, Netherlands, Italy, Belgium, United Kingdom, Slovenia, Ireland, Sweden, Denmark, Hungary, Finland, Norway, France, Czechia, Lithuania, Luxembourg, Serbia, Switzerland
  • Ohio State University
    Recruiting
    Long-Term Longitudinal QoL in Patients Undergoing EEA
    Chondrosarcoma | Chordoma | Meningioma | Craniopharyngioma | Encephalocele | Esthesioneuroblastoma | Pituitary Tumor | Rathke Cleft Cysts
    United States
  • LMU Klinikum
    University of Pisa; German Federal Ministry of Education and Research; European...
    Recruiting
    Global Registry and Natural History Study for Mitochondrial Disorders
    Mitochondrial Diseases | MDS | Mitochondrial Myopathies | MELAS Syndrome | MIDD | Kearns-Sayre Syndrome | MERRF Syndrome | Barth Syndrome | Leigh Syndrome | MNGIE | LHON | Pearson Syndrome | NARP Syndrome | Coenzyme Q10 Deficiency | SANDO | SCAE | MIRAS | CPEO
    Austria, Germany, Italy
  • Washington University School of Medicine
    Recruiting
    Immune Disorder HSCT Protocol
    Severe Combined Immunodeficiency | Chronic Granulomatous Disease | DiGeorge Syndrome | Hemophagocytic Lymphohistiocytosis | Wiskott-Aldrich Syndrome | X-linked Lymphoproliferative Syndrome | X-linked Agammaglobulinemia | Chediak-Higashi Syndrome | IPEX | Autoimmune Lymphoproliferative Syndrome | Common Variable... and other conditions
    United States
  • National Heart, Lung, and Blood Institute (NHLBI)
    National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
    Completed
    National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC)
    Marfan Syndrome | Turner Syndrome | Ehlers-Danlos Syndrome | Loeys-Dietz Syndrome | Shprintzen-Goldberg Syndrome | FBN1, TGFBR1, TGFBR2, ACTA2 or MYH11 Genetic Mutation | Bicuspid Aortic Valve Without Known Family History | Bicuspid Aortic Valve With Family History | Bicuspid Aortic Valve With Coarctation and other conditions
    United States
  • Anagnostou, Evdokia, M.D.
    The Hospital for Sick Children; Canadian Institutes of Health Research (CIHR); Alberta Health services and other collaborators
    Not yet recruiting
    Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders (CALM)
    Anxiety Disorders | Generalized Anxiety Disorder | Anxiety | Tuberous Sclerosis | ADHD | Neurodevelopmental Disorders | Autism Spectrum Disorder | Fragile X Syndrome | Social Anxiety | Social Anxiety Disorder | Agoraphobia | Tourette Syndrome | Tic Disorders | Autism | ADHD Predominantly Inattentive Type | ADHD - Combined... and other conditions
    Canada
  • RTI International
    University of North Carolina, Chapel Hill
    Enrolling by invitation
    Parent and Infant Inter(X)Action Intervention (PIXI)
    Tuberous Sclerosis | Down Syndrome | Duchenne Muscular Dystrophy | Prader-Willi Syndrome | Fragile X Syndrome | Rett Syndrome | Turner Syndrome | Williams Syndrome | Angelman Syndrome | Chromosome 22q11.2 Deletion Syndrome | Klinefelter Syndrome | Phelan-McDermid Syndrome | Dup15Q Syndrome | Smith Magenis Syndrome
    United States
  • Indiana University
    Recruiting
    Pathogenetic Basis of Aortopathy and Aortic Valve Disease (TAA)
    Aortic Valve Disease | Marfan Syndrome | Bicuspid Aortic Valve | Thoracic Aortic Aneurysm | Thoracic Aortic Dissection | Turner Syndrome | Vascular Ehlers-Danlos Syndrome | Familial Thoracic Aortic Aneurysm and Aortic Dissection | PHACE Syndrome | Aortopathies | Thoracic Aortic Disease | Thoracic Aortic Rupture and other conditions
    United States
  • Foundation Fighting Blindness
    Recruiting
    Inherited Retinal Degenerative Disease Registry (MRTR)
    Retinitis Pigmentosa | Choroideremia | Usher Syndrome | Batten Disease | Leber Congenital Amaurosis | Goldmann-Favre Syndrome | Kearns-Sayre Syndrome | Retinal Disease | Bardet-Biedl Syndrome | Stargardt Disease | Cone Dystrophy | Retinoschisis | Achromatopsia | Gyrate Atrophy | Eye Diseases Hereditary | Bassen-Kornzweig... and other conditions
    United States
  • Gynecologic Oncology Group
    National Cancer Institute (NCI)
    Completed
    Changes in Brain Function in Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Who Are Receiving Chemotherapy
    Ovarian Clear Cell Cystadenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Seromucinous Carcinoma | Ovarian Serous Cystadenocarcinoma | Stage IV Ovarian Germ Cell Tumor | Ovarian Sarcoma | Malignant Ovarian Epithelial Tumor | Ovarian Carcinosarcoma | Ovarian Brenner Tumor | Ovarian Mucinous... and other conditions
    United States
  • Fred Hutchinson Cancer Research Center/University...
    National Cancer Institute (NCI)
    Completed
    Internet-Based Program With or Without Telephone-Based Problem-Solving Training in Helping Long-Term Survivors of Hematopoietic Stem Cell Transplant Cope With Late Complications
    Depression | Fatigue | Primary Myelofibrosis | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone... and other conditions
    United States
  • Assistance Publique - Hôpitaux de Paris
    Not yet recruiting
    Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders (DANNIgene)
    Hemophilia A | Hemophilia B | Cystic Fibrosis | Sickle Cell Disease | Muscular Dystrophy, Duchenne | Fragile X Syndrome | Huntington Disease | Myotonic Dystrophy | Autosomal Recessive Polycystic Kidney Disease | Neurofibromatosis-Noonan Syndrome | Muscular Dystrophy, Becker | Invasive PreNatal Diagnosis in a... and other conditions
    France
  • Mayo Clinic
    Completed
    Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity
    Multiple Sclerosis | Rheumatoid Arthritis | Systemic Lupus Erythematosus | Uveitis | Vasculitis | Psoriasis | Graves Disease | Systemic Sclerosis | Celiac Disease | Crohn Disease | Type 1 Diabetes Mellitus | Myasthenia Gravis | Ulcerative Colitis | Dermatomyositis | Polymyositis | Vitiligo | Hepatitis, Autoimmune | Polymyalgia... and other conditions
    United States
  • dr. Laura C. G. de Graaff-Herder
    Recruiting
    GROWing Up With Rare GENEtic Syndromes (GROW UR GENES)
    Disorders of Sex Development | Congenital Adrenal Hyperplasia | Tuberous Sclerosis | Kallmann Syndrome | Prader-Willi Syndrome | Neurofibromatosis | Rett Syndrome | 22q11 Deletion Syndrome | Turner Syndrome | Noonan Syndrome | Allan-Herndon-Dudley Syndrome | Saethre-Chotzen Syndrome | Congenital Hypopituitarism | Cornelia... and other conditions
    Netherlands
  • City of Hope Medical Center
    National Cancer Institute (NCI); American Cancer Society (ACS) National Office
    Completed
    Family Caregiver Palliative Care Intervention in Supporting Caregivers of Patients With Stage II-IV Gastrointestinal, Gynecologic, Urologic and Lung Cancers
    Stage IIA Rectal Cancer | Stage IIB Rectal Cancer | Stage IIC Rectal Cancer | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Stage III Renal Cell Cancer | Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter | Recurrent Bladder Cancer | Recurrent Transitional... and other conditions
    United States
  • Global Healthy Living Foundation
    University of Alabama at Birmingham
    Recruiting
    PatientSpot Formerly Known as ArthritisPower (GHLF)
    Heart Failure | Stroke | Epilepsy | Multiple Sclerosis | Obesity | Diabetes | Chronic Obstructive Pulmonary Disease | Osteoarthritis | Rheumatoid Arthritis | Parkinson Disease | Peripheral Arterial Disease | Inflammatory Bowel Diseases | Amyotrophic Lateral Sclerosis | Psoriasis | Asthma | Muscular Dystrophy | Fibromyalgia | Alzheimer... and other conditions
    United States
  • St. Jude Children's Research Hospital
    Recruiting
    Familial Investigations of Childhood Cancer Predisposition (SJFAMILY)
    Pancreatic Cancer | Hodgkin Lymphoma | Lynch Syndrome | Tuberous Sclerosis | Fanconi Anemia | AML | Non Hodgkin Lymphoma | Familial Adenomatous Polyposis | Acute Leukemia | Nevoid Basal Cell Carcinoma Syndrome | Neurofibromatosis Type 1 | Neuroblastoma | Retinoblastoma | MDS | Rhabdomyosarcoma | Von Hippel-Lindau Disease | Adrenocortical Carcinoma and other conditions
    United States
  • Sanford Health
    National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaborators
    Recruiting
    Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)
    Mitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditions
    United States, Australia
  • Centre Hospitalier Universitaire de Liege
    Sanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaborators
    Recruiting
    Baby Detect : Genomic Newborn Screening
    Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditions
    Belgium
  • RTI International
    Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators
    Enrolling by invitation
    Early Check: Expanded Screening in Newborns
    Primary Hyperoxaluria Type 3 | Diabetes Mellitus | Hemophilia A | Hemophilia B | Hereditary Fructose Intolerance | Cystic Fibrosis | Factor VII Deficiency | Phenylketonurias | Sickle Cell Disease | Dravet Syndrome | Duchenne Muscular Dystrophy | Prader-Willi Syndrome | Fragile X Syndrome | Chronic Granulomatous Disease and other conditions
    United States

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