Clinical Trials on Afibrinogenemia, Congenital in Czechia

Total 58 results

Palacky University

Unknown

The Effect of Sensorimotor Insoles on Gait Parameters in Adults With Flexible Flatfoot

Flexible Flatfoot

Czechia
Charles University, Czech Republic

Completed

Neurophysiology-based Intervention of Foot Dysfunction in Sportive Children

Child Development | Sports Physical Therapy | Flatfoot, Flexible

Czechia
Charles University, Czech Republic
Anthropology and Human Genetics; Otorhinolaryngology, 2nd Faculty of Medicine; Department of Newborns with Intensive Care Unit

Unknown

Development of the Palate in Bilateral Orofacial Cleft Newborns One Year After Early Neonatal Cheiloplasty

Cleft Lip and Palate | Cleft Palate | Cleft Lip | Cleft Lip, Bilateral

Czechia
Charles University, Czech Republic

Recruiting

Physiotherapy Program Effect on Musculoskeletal Dysfunctions in Young Football Players

Balance; Distorted | Weak; Muscle | Flatfoot, Flexible | Pes Valgus | Pes Varus | Diastasis

Czechia
Institute for Clinical and Experimental Medicine
Sahlgrenska University Hospital, Sweden; University Hospital, Motol

Recruiting

Uterus Transplantation From Live Donors and From Deceased Donors - Clinical Study (UTxLD/DBD)

Infertility, Female | Mayer Rokitansky Kuster Hauser Syndrome | Absolute Uterine Factor Infertility | Mullerian Aplasia | Uterus; Absence, Congenital | Uterus Absence, Acquired

Czechia
University Hospital Hradec Kralove

Recruiting

Evaluation of the Severity of Right to Left Shunt in PFO Patients After Systemic Embolism

Embolism | Patent Foramen Ovale

Czechia
Aesculap AG
Raylytic GmbH

Recruiting

Post-Market Clinical Follow-Up Study on the Safety and Performance of Ennovate® Complex (COSINE)

Idiopathic Scoliosis | Hyperlordosis | Neuromuscular Scoliosis | Hyperkyphosis | Congenital Scoliosis

Czechia, Malaysia
Brno University Hospital
Masaryk University; Brno University of Technology

Recruiting

Use of Computer Aided Design and 3D Printing for Anesthesiology Management in a Pediatric Patient With Cleft Facial Defect (3D obturator)

Cleft Lip and Palate

Czechia
Brno University Hospital
Masaryk University

Active, not recruiting

Perioperative Analgesia in Neonates Who Underwent Primary Cleft Lip Repair Surgery

Perioperative Analgesia in Neonates

Czechia
Brno University Hospital
Masaryk University; Brno University of Technology

Recruiting

Use of Computer Aided Design and 3D Printing for Anesthesiology Management in a Pediatric Patient With Cleft Facial Defect (3D Obturator) - Pilot Trial (Pilobtur)

Cleft Lip and Palate

Czechia
Vascular surgery, University hospital Královské...
Belfast Health and Social Care Trust

Active, not recruiting

Validation of Arterio Venous Access Stage (AVAS) Classification (VAVASC)

Arteriovenous Fistula | Kidney Failure | Arteriovenous Graft | Dialysis Access Malfunction | Dialysis Related Complication

Czechia
University Hospital Olomouc
University Hospital Ostrava; Tomas Bata Hospital, Czech Republic; General University... and other collaborators

Recruiting

Surgical Treatment of Adrenal Diseases- Laparoscopic vs. Robotic-assisted Adrenalectomy

Cushing Syndrome | Pheochromocytoma | Adrenocortical Carcinoma | Adrenal Cortex Diseases | Adrenocortical Adenoma | Adrenal Tumor | Adrenalectomy; Status | Adrenal Mass | Adrenal Hyperplasia | Adrenal Disease | Adrenocortical Tumor | Conn Adenoma | Adrenal Gland Metastasis

Czechia
Actelion
Henry Ford Health System; Covance; Medidata Solutions; Almac Clinical Technologies and other collaborators

Terminated

An Upcoming Clinical Study to Measure the Safety and Impact of a Drug Called Macitentan in Teenage and Adult Fontan Patients. (RUBATO OL)

Congenital Heart Disease With Fontan Circulation

United Kingdom, Taiwan, France, Poland, China, Australia, Czechia, Canada, United States, Denmark, New Zealand
University Hospital, Motol

Completed

Respiratory Physiotherapy Performed by Simeox In Patients With Primary Ciliary Dyskinesia

Primary Ciliary Dyskinesia

Czechia
Saniona

Completed

Co-administration of Tesofensine/Metoprolol in Subjects With Prader-Willi Syndrome (PWS) (2016-003694-18)

Confirmed Genetic Diagnosis of Prader-Willi Syndrome

Czechia, Hungary
University Hospital Ostrava

Completed

Correlation of Right-left Shunt Detection in Cardioembolism Etiology in Stroke Patient.

Foramen Ovale Patent

Czech Republic
University Hospital, Motol

Completed

Nitrogen Bubble Detection After Simulated Dives in Divers With PFO and After PFO Closure

Patent Foramen Ovale

Czech Republic
Millendo Therapeutics US, Inc.

Terminated

Nevanimibe HCl for the Treatment of Classic CAH

Congenital Adrenal Hyperplasia

Spain, Israel, France, Brazil, Czechia
Actelion

Completed

Clinical Study Assessing the Efficacy and Safety of Macitentan in Fontan-palliated Subjects (RUBATO)

Congenital Heart Disease

United States, United Kingdom, Taiwan, Germany, France, Poland, China, Australia, Czechia, Canada, Denmark, New Zealand
DePuy International

Terminated

A Single Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Ceramic-on-ceramic Bearing in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

Czech Republic
Faculty Hospital Kralovske Vinohrady

Completed

The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic

Infections | Multiple Sclerosis | Autoimmune Diseases | Diabetes Mellitus, Type 1 | Rheumatoid Arthritis | Vaccine Reaction | Inflammatory Bowel Diseases | Psoriasis | Crohn Disease | Ulcerative Colitis | Down Syndrome | Atopic Dermatitis | Vitiligo | Alopecia Areata | COVID-19 Pandemic | Ankylosing Spondylitis | Lupus Erythematosus and other conditions

Czechia
Insel Gruppe AG, University Hospital Bern
Swiss National Science Foundation; Mach Gaensslen Foundation; Baxalta Innovations...

Recruiting

Genotype and Phenotype Correlation in Hereditary Thrombotic Thrombocytopenic Purpura (Upshaw-Schulman Syndrome) (TTP registry)

Thrombotic Thrombocytopenic Purpura | Congenital Thrombotic Thrombocytopenic Purpura | Familial Thrombotic Thrombocytopenic Purpura | Thrombotic Thrombocytopenic Purpura, Congenital | Upshaw-Schulman Syndrome

United States, Austria, Czechia, Germany, Japan, Norway, Switzerland
University Hospital Freiburg

Completed

Assessing Immune Function in Young Patients With Cytopenia That Did Not Respond to Treatment

Myelodysplastic Syndromes | Fanconi Anemia | Dyskeratosis Congenita | Pearson Marrow-pancreas Syndrome | Shwachman-diamond Syndrome

Spain, Germany, Switzerland, Austria, Netherlands, Italy, Czech Republic, Belgium, Denmark, Ireland
University College, London
University of Liverpool

Terminated

Evaluating Dietary Intervention Before surgicaL Treatment for Epilepsy (EDIBLE)

Cortical Dysplasia

United Kingdom, France, Austria, United States, Czechia, Germany, Italy, Switzerland
Medicem International CR s.r.o.

Completed

Dilapan-S/Dilasoft E-Registry in Induction of Labor (DSREGISTRYIL)

Labor; Forced or Induced, Affecting Fetus or Newborn | Labour Onset and Length Abnormalities

United States, Germany, Czechia, India, Russian Federation, Slovakia, United Kingdom
Boston Children's Hospital
Agios Pharmaceuticals, Inc.

Completed

Pyruvate Kinase Deficiency Natural History Study (PKD NHS)

Pyruvate Kinase Deficiency | Congenital Non-Spherocytic Hemolytic Anemia

United States, Germany, Canada, Czechia, Italy, Netherlands
Calliditas Therapeutics AB

Recruiting

A Study to Evaluate Setanaxib in Patients With Alport Syndrome

Alport Syndrome

United Kingdom, Spain, Czechia
MedImmune LLC

Completed

A Study to Evaluate MEDI-524 In Children With Hemodynamically Significant Congenital Heart Disease

Congenital Heart Disease

United States, Spain, United Kingdom, Canada, Belgium, Germany, Israel, Austria, Poland, Russian Federation, Sweden, Lebanon, France, Czech Republic, Hungary, Denmark, Bulgaria
Shire

Completed

Short Term Observational Study in DEB Patients

Dystrophic Epidermolysis Bullosa

United States, Czechia, Italy, Austria, Australia, France, Germany
Ferring Pharmaceuticals

Completed

An Open-Label, Multi-centre, Phase III Study of Local Tolerability of ZOMACTON 10MG

Turner's Syndrome

Czech Republic, France, Netherlands
Agios Pharmaceuticals, Inc.

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Regularly Transfused, Followed by a 5-Year Extension Period (ACTIVATE-KidsT)

Pediatric Pyruvate Kinase Deficiency | Pediatric Hemolytic Anemia

United States, Spain, Denmark, Turkey, Netherlands, Czechia, United Kingdom, Germany, Canada, Switzerland
DePuy International

Terminated

Multi-Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Resurfacing and Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral Fractures

Austria, Czech Republic, Finland, Germany, Norway, Portugal, Switzerland, United Kingdom
Agios Pharmaceuticals, Inc.

Completed

A Study to Evaluate Efficacy and Safety of AG-348 in Not Regularly Transfused Adult Participants With Pyruvate Kinase Deficiency (PKD)

Anemia, Hemolytic | Pyruvate Kinase Deficiency

United States, Spain, Switzerland, Turkey, Germany, France, United Kingdom, Japan, Netherlands, Brazil, Canada, Czechia, Denmark, Italy, Korea, Republic of, Thailand
Galapagos NV

Terminated

A Study to Evaluate the Effects of GLPG2737 in Participants With Autosomal Dominant Polycystic Kidney Disease (ADPKD)

Autosomal Dominant Polycystic Kidney Disease

Belgium, Netherlands, Italy, Spain, Czechia, Germany, Poland
Gedeon Richter Plc.

Completed

Study to Evaluate Efficacy, Safety, and Tolerability of RGH-706 in Prader-Willi Syndrome

Prader-Willi Syndrome

United States, Spain, France, Italy, Czechia
Agios Pharmaceuticals, Inc.

Recruiting

Pyruvate Kinase Deficiency Global Longitudinal Registry (PEAK Registry)

Pyruvate Kinase Deficiency

United States, Germany, Spain, Italy, United Kingdom, Czechia, France, Canada, Korea, Republic of, Netherlands, Turkey, Portugal, Denmark, Ireland, Switzerland, Thailand
Neurocrine Biosciences

Active, not recruiting

Global Safety and Efficacy Registration Study of Crinecerfont for Congenital Adrenal Hyperplasia (CAHtalyst)

Congenital Adrenal Hyperplasia

United States, Spain, Belgium, Austria, Bulgaria, Canada, Czechia, France, Germany, Greece, Israel, Italy, Netherlands, Poland, Portugal, Serbia, Sweden, United Kingdom
Ipsen

Completed

Study to Define Optimal IGF-1 Monitoring in Children Treated With NutropinAq (OPTIMA)

Renal Insufficiency, Chronic | Pituitary Diseases | Dwarfism | Turner Syndrome

France, Germany, Finland, Spain, Belgium, Czechia, Denmark, Greece, Italy, Romania, Russian Federation, Slovakia, Ukraine, United Kingdom
Merck KGaA, Darmstadt, Germany
Merck Serono S.A., Geneva

Completed

First Year Growth Response Associated Genetic Markers Validation Phase IV Open-label Study in Growth Hormone Deficient and Turner Syndrome Pre-pubertal Children: the PREDICT Pharmacogenetics Validation Study

Turner Syndrome | Idiopathic Growth Hormone Deficiency

Spain, France, Canada, United Kingdom, Czech Republic, Argentina, Germany, Italy, Sweden
Amryt Research Limited

Completed

Phase III Efficacy and Safety Study of Oleogel-S10 in Epidermolysis Bullosa (EASE)

Epidermolysis Bullosa

United States, Spain, Israel, Australia, France, Denmark, Switzerland, Italy, Hong Kong, Argentina, Austria, Brazil, Chile, Colombia, Czechia, Georgia, Germany, Greece, Hungary, Ireland, Romania, Russian Federation, Serbia, Singapore, U... and more
Dermatology Specialties Limited Partnership

Completed

Dose-Ranging Efficacy and Safety Study of Topical Rapamycin Cream for Facial Angiofibroma Associated With Tuberous Sclerosis Complex

Tuberous Sclerosis | Facial Angiofibroma

United States, Taiwan, Serbia, Spain, Australia, Czechia, Hungary, New Zealand, Slovakia
Sergiusz Jozwiak
Medical University of Vienna; Charite University, Berlin, Germany; Institut National... and other collaborators

Unknown

Long-term, Prospective Study Evaluating Clinical and Molecular Biomarkers of Epileptogenesis in a Genetic Model of Epilepsy - Tuberous Sclerosis Complex (EPISTOP)

Epilepsy | Tuberous Sclerosis Complex | TSC

Poland, Austria, Belgium, Czech Republic, France, Germany, Italy, Netherlands
Andreas L. Serra

Unknown

The Eurocyst Initiative: Building a Network of ADPKD Reference Centers Across Europe

Autosomal Dominant Polycystic Kidney Disease

France, Switzerland, Germany, Netherlands, Belgium, Czech Republic, Italy, Spain, Turkey, United Kingdom
Calcilytix Therapeutics, Inc., a BridgeBio company

Recruiting

Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1 (CALIBRATE)

Autosomal Dominant Hypocalcemia (ADH)

United States, Australia, United Kingdom, Denmark, Italy, France, Japan, Taiwan, Canada, Czechia, Netherlands
Novo Nordisk A/S

Completed

Safety and Efficacy of Turoctocog Alfa During Long-Term Treatment of Severe and Moderately Severe Haemophilia A (guardian™ 5)

Congenital Bleeding Disorder | Haemophilia A

Italy, Sweden, Netherlands, Austria, Spain, United States, Switzerland, Germany, France, Hungary, Greece, Slovenia, Czechia, Slovakia, Poland
Pierre Fabre Dermatology

Completed

Study to Demonstrate the Efficacy and Safety of Propranolol Oral Solution in Infants With Proliferating Infantile Hemangiomas Requiring Systemic Therapy

Infantile Hemangioma

Germany, United States, France, Spain, Peru, Australia, Lithuania, Italy, Canada, Czech Republic, Hungary, Mexico, New Zealand, Poland, Romania, Russian Federation
Novartis Pharmaceuticals

Withdrawn

Efficacy, Safety and Tolerability of Topically Applied LDE225 Cream (Hedgehog Pathway Inhibitor) in Adult Patients With Nevoid Basal Cell Carcinoma Syndrome (NBCCS)

Basal Cell Carcinoma

Greece, Switzerland, Germany, United Kingdom, Belgium, Canada, Czechia, Finland, Italy, Spain
Novo Nordisk A/S

Completed

Observational Prospective Study on Patients Treated With Norditropin®

Chronic Kidney Disease | Turner Syndrome | Noonan Syndrome | Chronic Renal Insufficiency | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Adult Growth Hormone Deficiency | Genetic Disorder | Foetal Growth Problem | Small for Gestational Age

Israel, Saudi Arabia, Spain, Argentina, Russian Federation, Germany, Netherlands, Italy, Belgium, United Kingdom, Slovenia, Ireland, Sweden, Denmark, Hungary, Finland, Norway, France, Czechia, Lithuania, Luxembourg, Serbia, Switzerland
Heidelberg University
Baxter Healthcare Corporation; Boehringer Ingelheim; Aventis Pharmaceuticals; European...

Completed

Effect of Strict Blood Pressure Control and ACE-Inhibition on Progression of Chronic Renal Failure in Pediatric Patients (ESCAPE)

Hypertension | Children | Chronic Renal Failure | Acquired Kidney Disease | Congenital Kidney Disease

Czech Republic, France, Germany, Hungary, Italy, Lithuania, Poland, Portugal, Serbia, Sweden, Switzerland, Turkey
Genzyme, a Sanofi Company

Terminated

A Medical Research Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients (STAGED-PKD)

Polycystic Kidney, Autosomal Dominant

Belgium, Germany, Czechia, United States, Italy, Poland, Argentina, Australia, Austria, Canada, China, Denmark, France, Israel, Japan, Korea, Republic of, Netherlands, Portugal, Romania, Spain, Taiwan, Turkey, United Kingdom

Clinical Trials on Afibrinogenemia, Congenital in Czechia

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Venezuela

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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