Clinical Trials on Age-Related Maculopathy

Total 52231 results

Smilebiotek Zhuhai Limited

Active, not recruiting

QA102 Phase II Study in Subjects With Dry AMD (AMEND)

Dry Age-related Macular Degeneration

United States
Bayer

Completed

Assessment of Proactive Treatments in Patients With Wet Age-related Macular Degeneration (wAMD) Which Have Never Undergone Treatment of This Particular Disease (XTEND)

Wet Age-related Macular Degeneration

Canada, Spain, Sweden, Belgium, Argentina, Italy, Korea, Republic of, United Kingdom, China, Denmark, France, Norway, Colombia, Australia, Ireland, Switzerland, Thailand
EyePoint Pharmaceuticals, Inc.

Completed

First in Human Study to Evaluate the Safety and Tolerability of EYP-1901 in Patients With Wet Age Related Macular Degeneration (wAMD)

Wet Age-related Macular Degeneration

United States
Bayer

Completed

Structured Post-marketing Surveillance to Collect the Safety Data of Intravitreal Aflibercept Injection (IVT-AFL) in Patients of Wet Age-related Macular Degeneration During Real World Clinical Practice

Wet Age-related Macular Degeneration

India
Ribomic USA Inc

Completed

A Multi-Center, Open Label, Extension Study Assessing the Efficacy and Safety of Additional Intravitreal Injections of RBM-007 in Subjects With Wet Age-related Macular Degeneration (RAMEN)

Exudative Age-related Macular Degeneration

United States
Novartis Pharmaceuticals

Completed

A Retrospective Study to Evaluate the Early Real-world Evidence of Brolucizumab in Patients With Neovascular Age-related Macular Degeneration (nAMD) in India

Neurovascular Age-related Macular Degeneration

India
Jarding, John, OD
i-Lumen Scientific, Inc.; Professor Timothy Jackson, King's College

Completed

Transpalpebral Microcurrent Stimulation for the Improvement of Visual Acuity in Patients With Macular Degeneration

Age-Related Macular Degeneration | Nonexudative Age-related Macular Degeneration
Janssen Research & Development, LLC

Completed

AAVCAGsCD59 for the Treatment of Wet AMD

Wet Age-related Macular Degeneration

United States
Moorfields Eye Hospital NHS Foundation Trust
Medical Research Council

Completed

Production of iPSC Derived RPE Cells for Transplantation in AMD

Age Related Macular Degeneration (AMD)
Novartis Pharmaceuticals

Completed

Real-world Evaluation of Brolucizumab for the Treatment of Neovascular (Wet) Age-related Macular Degeneration (AMD) (Komodo Health)

Age-related Macular Degeneration (AMD)

United States
Novartis Pharmaceuticals

Completed

Real-world Evaluation of Prevalence of Ocular Adverse Events in Patients With Neovascular (Wet) Age-related Macular Degeneration (AMD) Who Received Anti-vascular Endothelial Growth Factor (VEGF) Agents (Komodo Health)

Age-related Macular Degeneration (AMD)

United States
Novartis Pharmaceuticals

Completed

Characteristics of Patients With Neovascular Age-related Macular Degeneration Enrolled in the Brolucizumab Patient Support Services Program

Age-related Macular Degeneration (AMD)

United States
RemeGen Co., Ltd.

Completed

Evaluation the Pharmacokinetics,Safety,Tolerability of Single Intravitreal Injection RC28-E in Subjects With Wet Age-Related Macular Degeneration

Neovascular Age-related Macular Degeneration

China
Alkahest, Inc.

Completed

Evaluate the Therapeutic Effects and Safety of ALK4290 in Patients With Refractory Wet Age-Related Macular Degeneration

Wet Age-related Macular Degeneration

Hungary
University Hospital, Limoges

Unknown

Assessment of the Knowledge and Needs of Patients With AMD Before a Therapeutic Patient Education Program is Put in Place (DEMELE)

Age-related Macular Degeneration (AMD)

France
Qilu Pharmaceutical Co., Ltd.

Completed

Evaluating of the Safety, Pharmacokinetics and Pharmacodynamics of QL1205 and Lucentis® in Patients With Wet AMD

Wet Age-related Macular Degeneration

China
Medical University of Lublin

Completed

Blood-aqueous Barrier Integrity in Eyes Undergoing Intravitreal Bevacizumab Therapy to Treat Neovascular AMD

Exudative Age-related Macular Degeneration
National Eye Institute (NEI)

Completed

AMD Phenotype and Genotype Study

Age-Related Macular Degeneration | AMD

United States, Germany
Chinese Academy of Sciences
Beijing Tongren Hospital

Unknown

Subretinal Transplantation of Retinal Pigment Epitheliums in Treatment of Age-related Macular Degeneration Diseases

Dry Age-related Macular Degeneration

China
Novartis Pharmaceuticals

Completed

UNcovering the Difference Between Ranibizumab and Aflibercept, Focusing on Systemic Anti-vascular Endothelial Growth Factor (VEGF) Effects in Patients With neovascuLar Age-related Macular Degeneration (AMD) (UNRAVEL)

Neovacular Age-related Macular Degeneration

Taiwan, Thailand, Israel, Korea, Republic of, Philippines, Singapore, Malaysia
Pfenex, Inc

Completed

Safety Study of PF582 Versus Lucentis in Patients With Age Related Macular Degeneration

Age Related Macular Degeneration (AMD)

New Zealand
Affordance
Drescode

Completed

Macular Pigment Density Evolution in Unilateral Wet AMD Versus Non AMD Patients With or Without Lutein and Zeaxanthine Supplementation

Exudative Age-related Macular Degeneration

France
Medical University of Vienna

Completed

Retinal Effects After Combined Photodynamic Therapy (PDT) With Intravitreal Triamcinolone

Neovascular Age Related Macular Degeneration
MacuCLEAR, Inc.

Completed

Safety Study of a Topical Treatment for Dry Age Related Macular Degeneration

Nonexudative Age-related Macular Degeneration

United States
Merry, Graham, M.D.

Completed

Toronto and Oak Ridge Photobiomodulation Study for Dry Age Related Macular Degeneration (TORPA)

Nonexudative Age-related Macular Degeneration

United States, Canada
Apheresis Research Institute

Completed

Dry Age-Related Macular Degeneration (AMD) Treatment With Rheopheresis Trial (ART)

Dry Age Related Macular Degeneration

Germany
Shahid Beheshti University of Medical Sciences

Unknown

Intravitreal Bevacizumab vs. Bevacizumab Combined With Triamcinolone for Neovascular AMD

Neovascular Age-Related Macular Degeneration

Iran, Islamic Republic of
Indiana University

Recruiting

Cellular Scale Measures of Short-Term Retinal Atrophy Progression

Pigmentary Retinopathy | Pentosan Polysulfate Sodium Maculopathy | Pigmentary Maculopathy | Toxic Maculopathy | Interstitial Cystitis, Chronic

United States
LumiThera, Inc.

Recruiting

A Registry Study to Assess Photobiomodulation in Dry Age-Related Macular Degeneration (EUROLIGHT) (EUROLIGHT)

Dry Age-related Macular Degeneration

Norway
LumiThera, Inc.
National Eye Institute (NEI)

Recruiting

Study of Photobiomodulation to Treat Dry Age-Related Macular Degeneration (LIGHTSITEIIIB)

Dry Age-related Macular Degeneration

United States
VA Office of Research and Development
Augusta University

Not yet recruiting

Rehabilitating Vision Loss in Veterans With Age-Related Macular Degeneration (AMD)

Age-related Macular Degeneration (AMD)

United States
Mabwell (Shanghai) Bioscience Co., Ltd.

Recruiting

A Study to Evaluate the Efficacy and Safety of MW02 in the Treatment of nAMD

Wet Age-related Macular Degeneration

China
Bio-Thera Solutions

Completed

Clinical Study on the Efficacy and Safety of BAT5906 Injection

Wet Age-related Macular Degeneration

China
Ophthotech Corporation

Completed

ZIMURA in Combination With LUCENTIS in Patients With Neovascular Age Related Macular Degeneration (NVAMD)

Wet Age-related Macular Degeneration

United States, Hungary, Latvia
Bayer
Regeneron Pharmaceuticals

Completed

Observational Study to Assess Intravitreal Aflibercept Injections Used in a "Treat and Extend" Regimen in Treatment-naïve Wet Age-related Macular Degeneration Patients (ASTERIA)

Wet Age-related Macular Degeneration

Switzerland
Notal Vision Inc.

Completed

The Evaluation of the Agreement Between the NVHO in the Automatic Fluid Quantification and Cirrus OCT

Neovascular Age-related Macular Degeneration

United States
Clover Biopharmaceuticals AUS Pty Ltd

Withdrawn

Study of SCB-420 in Subjects With Neovascular Age-related Macular Degeneration

Wet Age-related Macular Degeneration
Notal Vision Inc.

Completed

Home OCT Repeatability and Reproducibility of Automatic Fluid Quantification Study

Neovascular Age-related Macular Degeneration

United States
Brugmann University Hospital

Completed

Effectiveness of Anti-VEGF Treatments in Wet AMD in Active Smokers

Wet Age-related Macular Degeneration

Belgium
RemeGen Co., Ltd.

Completed

Evaluation of RC28-E Injection in Wet Age-related Macular Degeneration

Wet Age-Related Macular Degeneration

China
Sinocelltech Ltd.

Unknown

The Study of Drug SCT510A in Patients With Wet Age-related Macular Degeneration (wAMD)

Wet Age-related Macular Degeneration
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Unknown

The Study of Drug 601 in Patients With Wet Age-related Macular Degeneration (wAMD)

Wet Age-related Macular Degeneration

China
Innovent Biologics (Suzhou) Co. Ltd.

Unknown

A Dose Escalation Study of IBI302 in Patients With Wet Age-related Macular Degeneration

Neovascular Age-related Macular Degeneration

China
Sucampo Pharma Americas, LLC
Sucampo Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Ocular Blood Flow Effects of Unoprostone Isopropyl in Adults With Dry Age-related Macular Degeneration

Dry Age-related Macular Degeneration

Austria
Alcon Research
Novartis Institutes for BioMedical Research

Terminated

Safety Tolerability and Efficacy of Intravitreal LMG324 in the Treatment of Neovascular Age-Related Macular Degeneration

Age-related Macular Degeneration (AMD)

United States
Novartis Pharmaceuticals

Completed

Systemic Vascular Endothelial Growth Factor (VEGF) Protein Dynamics Following Intravitreal Injections of Ranibizumab Versus Aflibercept in Patients With Neovascular Age-related Macular Degeneration (TIDE AMD)

Wet Age-Related Macular Degeneration

Germany
Novartis Pharmaceuticals

Completed

Efficacy of Ranibizumab Prn Treatment Compared to Aflibercept Bimonthly Intravitreal Injections on Retinal Thickness Stability in Patients With Wet AMD (SALT)

Neovascular Age-related Macular Degeneration

Germany, Austria, Belgium, Denmark, Switzerland, France, Netherlands, Portugal, Sweden, Norway
Bayer
Regeneron Pharmaceuticals

Completed

Investigating the Effectiveness of Eylea in Patients With Wet Age-related Macular Degeneration (PERSEUS)

Wet Age-related Macular Degeneration

Germany
Maturi, Raj K., M.D., P.C.

Completed

Sirolimus in Conjunction With Eylea vs Eylea Alone for Exudative AMD

Exudative Age Related Macular Degeneration

United States
Newtricious R&D BV
Sprim Advanced Life Sciences

Completed

Intervention Trial in Early Age-related Macular Degeneration (I-TEAM)

Age-related Macular Degeneration (AMD)

United States, Germany, Netherlands, United Kingdom

3

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