Clinical Trials on Alpha-1 Protease Inhibitor Deficiency in United States
Total 232 results
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University of FloridaRecruitingAlpha-1 Antitrypsin Deficiency | Cystic Fibrosis (CF) | AATD | AAT DeficiencyUnited States
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Inhibrx, Inc.CompletedAlpha-1 Antitrypsin Deficiency | AATDUnited States, New Zealand, United Kingdom
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Alnylam PharmaceuticalsTerminatedAntitrypsin Deficiency Liver DiseaseUnited Kingdom
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Beam Therapeutics Inc.Not yet recruitingAlpha 1-Antitrypsin DeficiencyUnited Kingdom
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Bristol-Myers SquibbCompletedHIV Infections | Protease InhibitorUnited States
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Bristol-Myers SquibbCompleted
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University of FloridaAlpha-1 Foundation; Brantly, Mark L., M.D.CompletedAlpha 1-Antitrypsin DeficiencyUnited States
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Dicerna Pharmaceuticals, Inc., a Novo Nordisk companyActive, not recruitingAlpha 1-Antitrypsin DeficiencyUnited Kingdom, United States, Ireland, Belgium, New Zealand, Spain, Netherlands, Portugal, Canada, Australia, France, Austria, Germany, Sweden
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Kamada, Ltd.Syneos HealthRecruitingAlpha 1-Antitrypsin DeficiencyUnited Kingdom, Sweden, Ireland, Netherlands, Belgium, Finland
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Washington University School of MedicineNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...CompletedEndoplasmic Reticulum Stress | HIV Related Insulin Resistance | Protease Inhibitor Related Insulin ResistanceUnited States
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National Heart, Lung, and Blood Institute (NHLBI)CompletedLung Diseases, Obstructive | Emphysema | Alpha 1-Antitrypsin DeficiencyUnited States
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Arrowhead PharmaceuticalsTerminatedAlpha-1 Antitrypsin DeficiencyAustralia, Netherlands, Germany, United Kingdom
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Mereo BioPharmaSyneos HealthCompletedEmphysema | Alpha 1-Antitrypsin Deficiency | COPDUnited Kingdom, Belgium, United States, Denmark, Canada, Sweden, Poland, Spain
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Arrowhead PharmaceuticalsCompletedAlpha 1-Antitrypsin DeficiencyUnited States, Spain, Netherlands, Germany, Italy, Portugal
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Medical University of South CarolinaCSL BehringCompletedSmoking | Emphysema | Alpha-1 Antitrypsin Deficiency | COPDUnited States
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Vertex Pharmaceuticals IncorporatedTerminatedAlpha 1-Antitrypsin DeficiencyUnited States, Germany, Canada, Ireland
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University of Massachusetts, WorcesterNational Heart, Lung, and Blood Institute (NHLBI); University of Florida; National... and other collaboratorsCompletedAlpha 1-Antitrypsin DeficiencyUnited States
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Arrowhead PharmaceuticalsActive, not recruitingAlpha 1-Antitrypsin DeficiencyAustria, Germany, United Kingdom
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University of Alabama at BirminghamNational Institutes of Health (NIH); Mereo BioPharmaCompletedEmphysema or COPD | Alpha-1 Antitrypsin Deficiency (AATD) | Pi*ZZ, Pi*SZ, Pi*Null, Another Rare Phenotype/Genotype Known to be Associated With Either Low or Functionally Impaired AAT Including F or I MutationsUnited States
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University of FloridaTerminatedChronic Obstructive Pulmonary Disease | Alpha-1 Antitrypsin DeficiencyUnited States
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Arbor Research Collaborative for HealthNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Active, not recruitingPortal Hypertension | Cholestasis | Liver Fibrosis | Biliary Atresia | Alagille Syndrome | Alpha1 Anti-Trypsin DeficiencyUnited States, Canada
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Gerard TurinoCompletedEmphysema | Alpha 1-Antitrypsin DeficiencyUnited States, Canada
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Columbia UniversityAlpha-1 FoundationRecruitingChronic Obstructive Pulmonary Disease | Acute Exacerbation Copd | Alpha-1 Anti-trypsin DeficiencyUnited States
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Columbia UniversityAlpha-1 Foundation; Stony Wold-Herbert Fund, Inc.CompletedChronic Obstructive Pulmonary Disease | Emphysema | Alpha-1 Antitrypsin DeficiencyUnited States
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Pharvaris Netherlands B.V.RecruitingHereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditionsUnited States, Puerto Rico
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University of Michigan Rogel Cancer CenterCSL Behring; The Leukemia and Lymphoma SocietyCompletedGraft vs Host DiseaseUnited States
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Medical University of South CarolinaNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)CompletedChronic PancreatitisUnited States
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Grifols Therapeutics LLCCompletedAlpha 1-Antitrypsin DeficiencyDenmark, Sweden, United Kingdom
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University of NottinghamNottingham University Hospitals NHS TrustRecruitingChronic Obstructive Pulmonary Disease | Alpha 1-Antitrypsin DeficiencyUnited Kingdom
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Columbia UniversityNational Heart, Lung, and Blood Institute (NHLBI); Alpha-1 FoundationActive, not recruitingAlpha 1-Antitrypsin Deficiency | Genetic DiseaseUnited States
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Pharvaris Netherlands B.V.RecruitingHereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditionsUnited States, Bulgaria, Czechia, Hungary, Spain, France, Germany, Poland, Canada, Israel
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Alpha-1 FoundationCompletedChronic Obstructive Pulmonary Disease | Alpha-1 Antitrypsin DeficiencyUnited States, Puerto Rico
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University of Colorado, DenverOmni Bio Pharmaceutical, Inc.CompletedDiabetes | Type 1 DiabetesUnited States
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Inhibrx, Inc.RecruitingEmphysema | Alpha 1-Antitrypsin DeficiencyUnited States, Australia, United Kingdom, New Zealand
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Virginia Commonwealth UniversityCompletedAcute Myocardial InfarctionUnited States
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John LevineNational Cancer Institute (NCI)CompletedGVHD | Graft-versus-host-diseaseUnited States
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Pharvaris Netherlands B.V.Active, not recruitingHereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditionsUnited States, Poland, Germany, Austria, Bulgaria, Canada, Ireland, Italy, United Kingdom
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Kamada, Ltd.CompletedEmphysemaUnited Kingdom, Canada, Denmark, Germany, Ireland, Netherlands, Sweden
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Arbor Research Collaborative for HealthNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)RecruitingLiver Diseases | Alpha 1-Antitrypsin Deficiency | Alagille SyndromeUnited States, Canada
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Pharvaris Netherlands B.V.CompletedHereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditionsBulgaria, United States, Spain, Israel, Germany, Canada, Czechia, France, Hungary, Italy, Netherlands, Poland, United Kingdom
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Stanford UniversityWithdrawnNeuromyelitis OpticaUnited States
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Eunice Kennedy Shriver National Institute of Child...Completed
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CSL BehringRecruitingAcute-graft-versus-host DiseaseUnited States, Korea, Republic of, Spain, Australia, Germany, Italy, Turkey, Japan
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University of North Carolina, Chapel HillNational Heart, Lung, and Blood Institute (NHLBI); Duke University; Vitrolife; XVIVO...CompletedBronchiectasis | Emphysema | Pulmonary Fibrosis | Cystic Fibrosis | Alpha-1 Antitrypsin Deficiency | Pulmonary Hypertension | Chronic Obstructive Pulmonary Disease (COPD) | SarcoidosisUnited States
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University of North Carolina, Chapel HillVitrolife; XVIVO PerfusionTerminatedBronchiectasis | Emphysema | Pulmonary Fibrosis | Cystic Fibrosis | Alpha-1 Antitrypsin Deficiency | Pulmonary Hypertension | Chronic Obstructive Pulmonary Disease (COPD) | SarcoidosisUnited States
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Zymenex A/SEuropean CommissionCompletedAlpha MannosidosisCzechia, Germany, Norway, United Kingdom
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Hoffmann-La RocheActive, not recruitingHemophilia A | Mild Hereditary Factor VIII Deficiency Disease Without Inhibitor | Moderate Hereditary Factor VIII Deficiency Disease Without InhibitorUnited States, Netherlands, Belgium, France, Germany, South Africa, Spain, Canada, United Kingdom, Poland
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University of Texas Southwestern Medical CenterRecruitingGlucose Transporter Type 1 Deficiency Syndrome | GLUT1 Deficiency Syndrome | Glucose Transporter type1 (GLUT-1) Deficiency | GLUT-1 Deficiency SyndromeUnited States
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Zymenex A/SEuropean CommissionCompletedAlpha-MannosidosisBelgium, Denmark, Spain, United Kingdom
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University of Texas Southwestern Medical CenterRecruitingGlucose Metabolism Disorders | Epilepsy | Glucose Transporter Type 1 Deficiency Syndrome | Glut1 Deficiency Syndrome 1 | Glut1 Deficiency Syndrome 1, Autosomal Recessive | Glucose Transporter Protein Type 1 Deficiency Syndrome | Glucose Transport DefectUnited States