Clinical Trials on Amyloidoza Beta2M

Total 430 results

Bioray Laboratories
Xiangya Hospital of Central South University; The 923rd Hospital of Joint Logistics...

Completed

Safety and Efficacy Evaluation of γ-globin Reactivated Autologous Hematopoietic Stem Cells

β Thalassemia Major

China
Bioray Laboratories
PLA 923 Hospital

Terminated

β-globin Restored Autologous HSC in β-thalassemia Major Patients

β-thalassemia Major

China
bluebird bio

Completed

A Study Evaluating the Safety and Efficacy of the LentiGlobin BB305 Drug Product in β-Thalassemia Major Participants

β-thalassemia Major

United States, Australia, Thailand
Massachusetts General Hospital
National Institute of Allergy and Infectious Diseases (NIAID)

Not yet recruiting

Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing (DACAT)

Drug Hypersensitivity | Drug-Induced Anaphylaxis | Antibiotic Allergy | Drug Allergy | Beta Lactam Adverse Reaction | Cephalosporin Allergy | Cephalosporin Reaction

United States
Beth Israel Deaconess Medical Center
Dana-Farber Cancer Institute; Philips Healthcare

Completed

CBCT-Guided Navigational Bronchoscopy For Lung Nodules

Lung; Node | Peripheral Pulmonary Nodules | Cone Beam Computed Tomography | Guided Navigation Bronchoscopy

United States
Protagonist Therapeutics, Inc.

Completed

Safety Study for Beta Thalassemia Subjects on PTG-300 (TRANSCEND)

β-thalassemia | Ineffective Erythropoiesis

Malaysia, Thailand, United States, Greece, United Kingdom, Turkey, Lebanon, Tunisia
Shiraz University of Medical Sciences

Completed

Combination Therapy of Hydroxyurea With L-Carnitine and Magnesium Chloride in Thalassemia Intermedia

β-Thalassemia Intermedia

Iran, Islamic Republic of
Prothya Biosolutions

Terminated

Apotransferrin in Patients With β-thalassemia

β-thalassemia Intermedia

Netherlands
Assiut University

Completed

Adiponectin, IL-6 and hsC-RP in Relation to Carotid Intima-media Thickness in B-thalassemia Patients

Thalassemia

Egypt
Novartis Pharmaceuticals

Withdrawn

An Open Label Study to Evaluate the Pharmacokinetics, Safety, Tolerability and Efficacy of Deferasirox Administered to Chinese Patients With β-thalassemia Major Aged From 2 to Less Than 6 Years Old (MACS2163)

β-thalassemia Major
Sun Yat-sen University

Recruiting

The Safety and Efficiency of Luspatercept in Chinese Adults With Transfusion Dependent β-thalassemia: a Real-world Study

Thalassemia Major | Transfusion-dependent Anemia

China
University of Milan
Luigi Sacco University Hospital

Completed

Effects of COVID-19 Infection on Beta-cell Function in Euglycemic Patients (COBETOX)

COVID19 | BETA-CELL FUNCTION

Italy
Ain Shams University

Unknown

Role of Vitamin C to Augment Iron Chelation With DFP or DFX

Thalassemia Major | Iron Chelation | Vitamin c

Egypt
Centre Hospitalier Universitaire, Amiens
Centre Hospitalier de Beauvais; University Hospital, Montpellier; University... and other collaborators

Recruiting

Comparison of Landiolol Versus Standard of Care for Prevention of Mortality in Patients Hospitalized for a Septic Shock With Hypercontractility (HyperBetashock)

Septic Shock | Tachycardia | Mortality During Septic Shock | Beta-blocker

France
BGI-research
Shenzhen Children's Hospital

Not yet recruiting

Safety and Efficacy Evaluation of β-globin Restored Autologous Hematopoietic Stem Cells in β-thalassemia Major Patients

β-Thalassemia Major

China
Rambam Health Care Campus
Canadian Institutes of Health Research (CIHR); Hadassah Medical Organization; McGill University Health Centre/Research Institute of the McGill University Health Centre and other collaborators

Recruiting

PipEracillin Tazobactam Versus mERoPENem for Treatment of Bloodstream Infections Caused by Cephalosporin-resistant Enterobacteriaceae (PETERPEN) (PETERPEN)

Bacteremia | Enterobacteriaceae Infections | Beta Lactam Resistant Bacterial Infection

Israel, Canada
Aghia Sophia Children's Hospital of Athens

Unknown

B Memory Cell Response to Vaccination With the 13-valent Pneumococcal Conjugate Vaccine in Asplenic Individuals

Asplenia | β-thalassemia Major

Greece
Cairo University

Recruiting

Correlation Between Pulmonary Functions and Physical Fitness in Children With β-thalassemia

Pulmonary Function | Physical Fitness | β-Thalassemia

Egypt
Hamad Medical Corporation

Recruiting

Beta Blocker Use In Traumatic Brain Injury Based On The High-Sensitive Troponin T Status (BBTBBT)

Brain Injuries | Trauma | Troponin | Stress Reaction | Beta Blockers

Qatar
Providence Health & Services
AstraZeneca

Completed

Angiotensin II Antagonism of TGF-Beta 1

Hypertension | Diabetic Nephropathy

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Longitudinal Study on the QoL of Pediatric Patients After HSCT and Its Influencing Factors

Acute Leukemia | Thalassemia Major

China
University of Alberta

Recruiting

De-Adoption of Beta-Blockers in Patients With Stable Ischemic Heart Disease (ABBREVIATE)

Coronary Artery Disease | Stable Ischemic Heart Disease | Beta-blocker Therapy

Canada
Memorial Sloan Kettering Cancer Center

Active, not recruiting

ß-Thalassemia Major With Autologous CD34+ Hematopoietic Progenitor Cells Transduced With TNS9.3.55 a Lentiviral Vector Encoding the Normal Human ß-Globin Gene

Confirmed Diagnosis of ß-thalassemia Major

United States
Invenux, LLC
State University of New York - Downstate Medical Center

Active, not recruiting

Dose-Escalation Study of SCD-101 in Sickle Cell Disease

Sickle Cell Disease | Sickle-Beta Zero Thalassemia

United States
Protagonist Therapeutics, Inc.

Completed

Study of PTG-300 in Non-Transfusion Dependent and Transfusion-Dependent Beta-Thalassemia Subjects With Chronic Anemia (TRANSCEND)

Chronic Anemia | β-thalassemia | Ineffective Erythropoiesis

United States, Malaysia, Turkey, Thailand, United Kingdom, Italy, Lebanon, Tunisia, Greece
Assiut University

Unknown

Sexual Maturation in β-Thalassemia Major Patients in Assiut University Hospital

β-Thalassemia Major Patients Receiving Chelation Therapy
University Hospital, Brest

Completed

Optimization Management Study of Community Urinary Tract Infections Spectrum (OPTICUR-EBLSE)

Urinary Tract Infections | Community-Acquired Infections | Resistant Infection | Beta Lactam Resistant Bacterial Infection
Life Molecular Imaging SA

Completed

Phase II Study of Florbetaben (BAY 94-9172) PET Imaging for Detection/Exclusion of Cerebral β-amyloid in Patients With Probable Alzheimer's Disease Compared to Healthy Volunteers

Alzheimer Disease | Amyloid Beta-Protein

United States, Switzerland, Australia, Germany, Japan
National Institute of Allergy and Infectious Diseases...

Terminated

Stem Cell Transplantation After Reduced-Dose Chemotherapy for Patients With Sickle Cell Disease or Thalassemia

Anemia, Sickle Cell | Hemoglobinopathies | Thalassemia | Hemoglobin SC Disease | Thalassemia Major

United States
Assiut University

Not yet recruiting

Thyroid Function , HbA1c in Relation to Ferritin Level in Adullt Patient e B Thalassemia

B Thalassemia
Timothy Olson

Active, not recruiting

Pilot Study PBSCT With TCRab Depletion For Hemoglobinopathies

Sickle Cell Disease | Thalassemia Major

United States
Qianfoshan Hospital

Completed

Risk Factors and Machine Learning Model for Beta-Lactam Drugs Related Acute Kidney Injury

Acute Kidney Injury | Beta-Lactam Antibiotic Toxicity (Diagnosis)

China
Shenyang Northern Hospital

Unknown

A Randomized, Two-arm, Open Label Study to evalUate the Effect of a Smart Phone-based Patient Support Tool On Patient AdheRence of Treatment in Stable Angina Patients Prescribed Beta-blockers in China (SUPPORT)

Medication Adherence | Mobile Applications | Stable Angina Pectoris | Adrenergic Beta-Antagonists
Augusta University
Yale University; University of Alabama at Birmingham; Tufts University

Unknown

Vitamin K and Glucose Metabolism in Adults at Risk for Diabetes (Vita-K 'n' Adults Study)

Obesity | Insulin Resistance | Insulin Sensitivity | Prediabetes | Beta-Cell Dysfunction

United States
Assiut University

Not yet recruiting

Assessment of Cognitive Functions, Psychological Symptoms, and Quality of Life Among B Thalassemia Patients and Their Clinical Correlates.

B Thalassemia
Clinica Universidad de Navarra, Universidad de...
Instituto de Salud Carlos III

Completed

Dysfunctional Adiposity and Glucose Impairment (DICAMANO)

Insulin Resistance | Body Composition | Cardiovascular Risk Factor | Obesity, Abdominal | Visceral Obesity | Carbohydrate Intolerance | Beta-cell Function | Oral Glucose Tolerance Test
Assiut University

Unknown

Quality of Life and Treatment Satisfaction in β-Thalassemia Patients Receiving Deferasirox

β-thalassemia

Egypt
Lin Chen

Completed

Esmolol in Sepsis Management:Evaluating Immunomodulatory Effects and Impact on Patient Outcomes

Sepsis | Cytokine Storm | Sympathetic Nervous System Diseases | Catecholamine; Overproduction | Immunologic Paralysis | Lymphocyte Disorder T | Beta-Blocker

China
Maastricht University Medical Center

Completed

Restriction of Dietary AGEs to Prevent Diabetes in Overweight Individuals

Diet | Vascular Function | Insulin Sensitivity/Resistance | Beta-cell Function | Advanced Glycation Endproducts | AGEs

Netherlands
Arizona Oncology Services

Unknown

Use of Organic Germanium or Placebo for the Prevention of Radiation Induced Fatigue

Localized Breast Cancer | Localized Prostate Cancer | Patients Receiving External Beam Radiotherapy

United States
Assiut University

Not yet recruiting

NAC Effect on Iron Overload and Blood Transfusion in β-thalassemia Major

Thalassemia Major
Centre Hospitalier Universitaire, Amiens

Completed

Neurotoxicity Evaluation of Beta-lactams in Intensive Care Unit and Identification of the Risk Factors (NebuLar)

Sepsis | Acute Kidney Injury | Neurotoxicity | Critical Care | Therapeutic Drug Monitoring | Beta Lactams
University Hospital Olomouc
Palacky University

Recruiting

Effect of Beta-alanine and Pelvic Floor Muscle Training on Urinary Incontinence After Radical Prostatectomy (BELA) (BELA)

Urinary Incontinence | Prostate Cancer | Radical Prostatectomy | Pelvic Floor Muscle Training | Beta-Alanine

Czechia
University of Campinas, Brazil
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Amlodipine Use in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major (AnloThal)

Thalassemia Major

Brazil
Vanderbilt University Medical Center
Washington University School of Medicine; University of Alabama at Birmingham

Recruiting

Epidemiology of Silent and Overt Strokes in Sickle Cell Disease (ESCD)

Stroke | Sickle Cell Disease | Anemia, Sickle Cell | Sickle Cell Thalassemia | Sickle Cell-Beta0-Thalassemia

United States
Beni-Suef University

Completed

The Effect of N-acetylcysteine on Oxidative Stress Status and Iron Overload in Thalassemia Major

Thalassemia Major

Egypt
HaEmek Medical Center, Israel

Unknown

A Case Control Study to Evaluate the Cognitive and Brain Function of β-thalassemia Patients.

Thalassemia | Brain Function (Measured by ERP Level)

Israel
University of Campinas, Brazil
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Amlodipine in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major (AmloThal)

Iron Overload | Thalassemia

Brazil
Beni-Suef University
University of Arizona; Maternity and Children Hospital, Makkah; Beni-Suef Health...

Completed

Hydroxy Urea, Omega 3, Nigella Sativa,Honey on Oxidative Stress and Iron Chelation in Pediatric Major Thalassemia

Iron Overload | Oxidative Stress | Thalassemia Major

Egypt, Saudi Arabia
University of California, San Francisco

Recruiting

International Registry of Patients With Alpha Thalassemia (ATM Registry)

Alpha-Thalassemia | Alpha Thalassemia Major | Alpha Thalassemia Minor

United States

Clinical Trials on Amyloidoza Beta2M

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Ghana

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Rare Diseases

Drug Interventions

Dietary Supplements

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