Clinical Trials on Anaemia in United Kingdom

Total 1853 results

Affymax

Completed

Study of Subcutaneously Administered Peginesatide in Anemic Cancer Patients Receiving Chemotherapy

Cancer | Chemotherapy Induced Anemia

Czech Republic, Poland, United Kingdom
Vertex Pharmaceuticals Incorporated
CRISPR Therapeutics

Recruiting

Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Transfusion-Dependent β-Thalassemia (TDT)

Hematologic Diseases | Genetic Diseases, Inborn | Hemoglobinopathies | Thalassemia | Beta-Thalassemia

United States, Germany, Italy, United Kingdom, Canada
Vertex Pharmaceuticals Incorporated
CRISPR Therapeutics

Recruiting

Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Severe Sickle Cell Disease (SCD)

Sickle Cell Disease | Hemoglobinopathies | Hematological Diseases | Hydroxyurea Failure | Hydroxyurea Intolerance

United States, Italy, United Kingdom, Germany
Royal Marsden NHS Foundation Trust

Unknown

Improving Diagnosis in Idiopathic Cytopenia Using Gene Sequencing

Cytopenia

United Kingdom
University of Edinburgh
NHS Lothian; Chief Scientist Office of the Scottish Government; Transfusion Medicine...

Completed

Restrictive and Liberal Transfusion Strategies in Intensive Care (RELIEVE)

Anemia | Blood Transfusion | Intensive Care

United Kingdom
Memorial Sloan Kettering Cancer Center

Completed

Assess the Feasibility and Safety of Granulocyte Colony Stimulating Factor (GCSF) Mobilization of CD34+ Hematopoietic Progenitor Cells in Patients With Betathalassemia Major

Beta Thalassemia Major | Congenital Anemias

United States
Pharmacosmos A/S
Max Neeman International

Completed

Iron Oligosaccharide in Inflammatory Bowel Disease Subjects With Iron Deficiency Anaemia

Inflammatory Bowel Disease

United Kingdom, Denmark, India
TME Pharma AG

Completed

First-in-human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of NOX-H94

Inflammation | Anemia | Chronic Diseases

United Kingdom
Silence Therapeutics plc

Withdrawn

Study in Beta-thalassaemia or Myelodysplastic Syndrome Patients to Investigate the Safety and Tolerability of SLN124

Non-transfusion-dependent Thalassemia | Low Risk Myelodysplastic Syndrome

United Kingdom, Bulgaria
Novartis Pharmaceuticals

Completed

Study of Efficacy, Safety and Tolerability of ACZ885 (Canakinumab) in Pediatric and Young Adult Patients With Sickle Cell Anemia

Sickle Cell Anemia

Turkey, United States, Germany, Canada, United Kingdom, Israel, South Africa
Novartis Pharmaceuticals

Completed

A Two-part Single- and Repeat-dose Study of CSJ137 in Anemic Chronic Hemodialysis Patients

Anemia, Iron-Deficiency

Czechia, Israel, United States, United Kingdom
Regeneron Pharmaceuticals

Completed

Pozelimab and Cemdisiran Combination Therapy in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria Who Switch From Eculizumab Therapy

Paroxysmal Nocturnal Hemoglobinuria

United Kingdom
European Society for Blood and Marrow Transplantation
Genzyme, a Sanofi Company

Completed

Rabbit Antithymocyte Globulin (Thymoglobuline) With Ciclosporin for Patients With Acquired Aplastic Anaemia (RATGAA07)

Aplastic Anemia

Switzerland, United Kingdom, Germany, Italy, France, Saudi Arabia
Boston University

Completed

Phase II Study of Arginine Butyrate With or Without Epoetin Alfa in Patients With Thalassemia Intermedia

Beta-Thalassemia

United States, United Kingdom
St George's, University of London

Unknown

Emergency Cerclage in Twin Pregnancies at Imminent Risk of Preterm Birth: an Open-Label Randomised Controlled Trial (ENCIRCLE)

Preterm Birth | Twin Pregnancy With Antenatal Problem | Twin to Twin Transfusion Syndrome

United Kingdom
Stichting Hemato-Oncologie voor Volwassenen Nederland

Completed

Cytarabine and Daunorubicin With or Without Gemtuzumab Ozogamicin in Treating Older Patients With Acute Myeloid Leukemia or Myelodysplastic Syndromes

Myelodysplastic Syndromes | Leukemia

United Kingdom
Alnylam Pharmaceuticals

Completed

A Phase 1/2 Study of an Investigational Drug, ALN-CC5, in Healthy Adult Volunteers and Patients With PNH

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Spain, United Kingdom
Sanofi

Active, not recruiting

Efficacy, Safety and Pharmacokinetics of Rilzabrutinib in Patients With Warm Autoimmune Hemolytic Anemia (wAIHA)

Warm Autoimmune Hemolytic Anemia (wAIHA)

United States, Austria, China, Denmark, Germany, Hungary, Italy, Spain, United Kingdom
Medical Research Council
King's College London

Completed

Questionnaire to Assess Gastrointestinal Symptoms of Oral Iron.

Abdominal Pain | Constipation | Diarrhea | Anemia | Heartburn | Side Effect

United Kingdom
Celgene

Terminated

Study to Determine the Safety and Tolerability of Sotatercept (ACE-011) in Adults With Beta( β)- Thalassemia.

Beta Thalassemia Intermedia | Beta Thalassemia Major

France, United Kingdom, Italy, Greece
Immunovant Sciences GmbH

Terminated

To Assess the Efficacy and Safety of RVT-1401 in the Treatment of Warm Autoimmune Hemolytic Anemia (ASCEND-WAIHA). (ASCEND-WAIHA)

Warm Autoimmune Hemolytic Anemia

United States, Korea, Republic of, Israel, United Kingdom, Spain, Thailand
bluebird bio

Completed

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia, Who do Not Have a β0/β0 Genotype

Beta-Thalassemia

France, United Kingdom, United States, Thailand, Italy, Germany
Regeneron Pharmaceuticals

Recruiting

REGN7257 in Adult Patients With Severe Aplastic Anemia That Is Refractory to or Relapsed on Immunosuppressive Therapy

Severe Aplastic Anemia (SAA)

United States, France, Korea, Republic of, United Kingdom
Peterborough and Stamford Hospitals NHS Foundation...
Peterborough Hospitals Hip Fracture Project

Completed

Randomised Trial Comparing Iron Supplementation Versus Placebo in the Treatment of Anaemia After Hip Fracture

Hip Fracture

United Kingdom
CSL Behring

Completed

Safety of Single Doses of CSL889 in Adult Patients With Sickle Cell Disease

Sickle Cell Disease

United States, United Kingdom, Netherlands
bluebird bio

Completed

A Study Evaluating the Efficacy and Safety of the LentiGlobin® BB305 Drug Product in Participants With Transfusion-Dependent β-Thalassemia

Beta-Thalassemia

United States, Germany, United Kingdom, France, Greece, Italy
Celgene
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway...

Completed

A Study to Determine the Efficacy and Safety of Luspatercept in Adults With Non Transfusion Dependent Beta (β)-Thalassemia (BEYOND)

Thalassemia

United States, Greece, Italy, Lebanon, Thailand, United Kingdom
Imperial College London
Fu Wai Hospital, Beijing, China

Completed

IV Iron Replacement for Iron Deficiency in Idiopathic Pulmonary Arterial Hypertension (IPAH) Patients

Pulmonary Arterial Hypertension | Iron Deficiency

United Kingdom, China, Germany
Pfizer

Completed

Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Study Of PF-04447943, Co-Administered With And Without Hydroxyurea, In Subjects With Stable Sickle Cell Disease

Phase 1 Sickle Cell

United States, United Kingdom, Belgium, Netherlands, Italy
Sangart

Withdrawn

Phase 2 Study of MP4CO to Treat Vaso-occlusive Sickle Crisis

Sickle Cell Disease | Anemia, Sickle Cell | Sickle Cell Anemia | Hemoglobin SC Disease | Sickle Cell Disorders | Sickle Cell Hemoglobin C Disease

France, United Kingdom, Netherlands, Turkey, Bahrain, Belgium, Brazil, Lebanon, Qatar
European Society for Blood and Marrow Transplantation
Novartis; Pfizer

Completed

hATG+CsA vs hATG+CsA+Eltrombopag for SAA (RACE)

Severe Aplastic Anemia

Switzerland, Netherlands, France, Italy, Spain, United Kingdom
Vertex Pharmaceuticals Incorporated
CRISPR Therapeutics

Enrolling by invitation

A Long-term Follow-up Study in Participants Who Received CTX001

Hematologic Diseases | Genetic Diseases, Inborn | Sickle Cell Disease | Hemoglobinopathies | Sickle Cell Anemia | Thalassemia | Beta-Thalassemia

United States, Belgium, Canada, Italy, United Kingdom, Germany
Manchester University NHS Foundation Trust

Withdrawn

Does Cardiopulmonary Bypass Change Olfaction? (Anosmia)

Anosmia

United Kingdom
BioCryst Pharmaceuticals

Completed

First-in-Human Study of BCX9930 in Healthy Volunteers and Patients With PNH

Paroxysmal Nocturnal Hemoglobinuria

United Kingdom, Austria, South Africa
AstraZeneca

Completed

A Study to Assess the Effect of Ticagrelor in Reducing the Number of Days With Pain in Patients With Sickle Cell Disease (Hestia2)

Sickle Cell Disease

United States, Italy, France, United Kingdom, Turkey, Egypt, Lebanon, Kenya
Vertex Pharmaceuticals Incorporated
CRISPR Therapeutics

Active, not recruiting

A Safety and Efficacy Study Evaluating CTX001 in Subjects With Severe Sickle Cell Disease

Sickle Cell Disease | Hemoglobinopathies | Hematological Diseases

United States, Belgium, Canada, France, Germany, Italy, United Kingdom
Pfizer

Completed

Study Evaluating 13-valent Pneumococcal Conjugate Vaccine (13vPnC) in Children With Sickle Cell Disease

Pneumococcal Conjugate Vaccine

France, United States, United Kingdom, Lebanon, Italy, Egypt, Saudi Arabia
GlaxoSmithKline

Completed

Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat-Three-times Weekly Dosing in Dialysis (ASCEND-TD)

Anaemia

Korea, Republic of, Russian Federation, Spain, United States, Australia, United Kingdom, Brazil, Italy, Argentina, Poland, Romania, France, Canada
GlaxoSmithKline

Completed

Evaluation of Dose Response Relationship, Safety and Efficacy of GSK1278863 in Hemodialysis-dependent Subjects With Chronic Kidney Disease Associated Anemia

Anaemia

United States, Australia, Korea, Republic of, Canada, Czechia, Norway, Spain, United Kingdom, Russian Federation, Germany, Sweden, Denmark, Poland, France, Hungary, Japan
GlaxoSmithKline

Completed

A Study to Evaluate Safety and Efficacy of GSK1278863 in Non-Dialysis Dependent (NDD) Subjects With Anemia Associated With Chronic Kidney Diseases (CKD)

Anaemia

United States, Australia, Canada, Hungary, Spain, Sweden, Czechia, Germany, United Kingdom, Korea, Republic of, Russian Federation, France, Denmark, Poland, Japan
NHS Lothian

Completed

Restrictive vs Liberal Transfusion Strategy on Cardiac Injury in Patients Undergoing Surgery for Fractured Neck Of Femur (RESULT-NOF)

Anemia | Kidney Injury | Cardiac Event | Fractured Hip

United Kingdom
Beth Israel Medical Center

Completed

Extended Platelet Parameters as a Means to Differentiate Immune Thrombocytopenia From Hypo-proliferative Thrombocytopenias.

Immune Thrombocytopenia | Myelodysplasia | Chemotherapy Induced Thrombocytopenia | Aplastic Anaemia

United States
Entia Ltd

Withdrawn

Project Aura: Co-design of a Home-based Monitoring Service

Anemia of Chronic Kidney Disease

United Kingdom
HealthCore-NERI
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Evaluating the Safety of Two Medications to Treat Hepatitis C in People With Thalassemia (The HepC Study) (HepC)

Hepatitis C | Thalassemia

United States, United Kingdom, Canada
GlaxoSmithKline

Completed

Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat-in Incident Dialysis (ASCEND-ID)

Anaemia

United States, Korea, Republic of, Argentina, Spain, Australia, Canada, Russian Federation, United Kingdom, Malaysia, Italy, Poland, Germany, India, Mexico, South Africa
Shire

Completed

Safety and Pharmacodynamic Study of an Oral Iron Chelator Given for 6 Months to Patients With Iron Overload

Beta-thalassemia | Transfusional Iron Overload

United States, United Kingdom, Italy, Thailand, Turkey
Pharmacosmos A/S
BioStata

Completed

A Non-interventional Study of Diafer in Subjects With CKD on Haemodialysis for Treatment of Iron Deficiency (DINO)

Anaemia in Chronic Kidney Disease

Sweden, United Kingdom
Vifor Fresenius Medical Care Renal Pharma
Worldwide Clinical Trials; Fresenius Medical Care Deutschland GmbH

Terminated

Artificial Intelligence for Optimal Anemia Management in End-stage Renal Disease: The Anemia Control Model (ACM) Trial (ANEMEX)

Anemia | End Stage Renal Disease

United Kingdom
Vertex Pharmaceuticals Incorporated
CRISPR Therapeutics

Active, not recruiting

A Safety and Efficacy Study Evaluating CTX001 in Subjects With Transfusion-Dependent β-Thalassemia

Hematologic Diseases | Genetic Diseases, Inborn | Hemoglobinopathies | Thalassemia | Beta-Thalassemia

United States, United Kingdom, Canada, Germany, Italy
Vifor (International) Inc.
Fortrea

Completed

Study to Assess Efficacy and Safety of VIT-2763 (Vamifeport) in Subjects With Sickle Cell Disease (ViSionSerenity)

Sickle Cell Disease

United States, France, Greece, Lebanon, United Kingdom

Clinical Trials on Anaemia in United Kingdom

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