Clinical Trials on Analgesic Response

Total 4657 results

Henry Ford Health System

Terminated

Safety and Efficacy of Strategy to Prevent Drug-Induced Nephrotoxicity in High-Risk Patients (STOP-NT)

Bacteremia | Endocarditis | Acute Bacterial Skin and Skin Structure Infections | Health Care Associated Pneumonia | Osteomyelitis/Septic Arthritis

United States
AIO-Studien-gGmbH
Novartis Pharmaceuticals; Assign Data Management and Biostatistics GmbH

Completed

Safety and Tolerability of Everolimus as Second-line Treatment in Poorly Differentiated Neuroendocrine Carcinoma / Neuroendocrine Carcinoma G3 (WHO 2010) and Neuroendocrine Tumor G3 - an Investigator Initiated Phase II Study (EVINEC)

Neuroendocrine Carcinoma, Grade 3 | Poorly Differentiated Malignant Neuroendocrine Carcinoma | Neuroendocrine Carcinoma, Grade 1 [Well-differentiated Neuroendocrine Carcinoma] That Switched to G3 | Neuroendocrine Carcinoma, Grade 2 [Moderately Differentiated Neuroendocrine Carcinoma]... and other conditions

Germany
Aga Khan University
Department for International Development, United Kingdom

Completed

Improved Accessibility of EmONC Services for Maternal and Newborn Health: a Community Based Project (EmONC)

Pneumonia | Sepsis | Eclampsia | Respiratory Distress Syndrome | Postpartum Hemorrhage | Omphalitis | Birth Asphyxia | Puerperal Sepsis

Pakistan
Hospital General Universitario Gregorio Marañon
Instituto de Salud Carlos III

Recruiting

Cell Therapy With Treg Cells Obtained From Thymic Tissue (thyTreg) to Control the Immune Hyperactivation Associated With COVID-19 and/or Acute Respiratory Distress Syndrome (THYTECH2) (THYTECH2)

Systemic Inflammatory Response Syndrome

Spain
St. Jude Children's Research Hospital

Recruiting

Cardiovascular Magnetic Resonance Prognosticators in Pediatric Oncology Patients With Sepsis

Sepsis | Acute Respiratory Distress Syndrome | Cardiovascular Shock

United States
University of Alabama at Birmingham

Recruiting

Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to CAR-T Cell Therapy

Lymphoma, Non-Hodgkin | Multiple Myeloma | Acute Lymphoblastic Leukemia | Cytokine Release Syndrome | ICANS

United States
Aveni Foundation

Withdrawn

CORONA: A Study Using DeltaRex-G Gene Therapy for Symptomatic COVID-19 (CORONA)

COVID-19 | Acute Respiratory Distress Syndrome | Cytokine Storm
Biocon Limited

Completed

Efficacy and Safety of Itolizumab in COVID-19 Complications

Covid19 | Acute Respiratory Distress Syndrome | Cytokine Release Syndrome

India
Johns Hopkins University
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Completed

CHAMPS Study: Chronic HepAtitis C Management to ImProve OutcomeS (CHAMPS)

Human Immunodeficiency Virus | Hepatitis C Virus Infection, Response to Therapy of

United States
SCARE (Study group for carbapenem resistance)

Unknown

Development of Risk Score Model and Decision Tree Algorithm for Predicting Infections With CRKp in Colonized Patients (DETERMINE)

Central Nervous System Infections | Pneumonia, Bacterial | Urinary Tract Infections | Intra-abdominal Infection | Osteomyelitis | Bloodstream Infection | Acute Bacterial Skin and Skin Structure Infection

Turkey
Tuberculosis Research Centre, India
International Union Against Tuberculosis and Lung Diseases; Sarvodaya Charitable... and other collaborators

Active, not recruiting

Modified BPaL Regimen for Managing Pre-XDR TB and MDR (TI/NR) TB in India (mBPaL)

Pre-Extensively Drug-Resistant Pulmonary TB | Treatment Intolerant Multidrug-Resistant Pulmonary TB | Non-responsive Multidrug-Resistant Pulmonary TB

India
Joseph M. Still Research Foundation, Inc.

Recruiting

Association of Cytokines With the Development of Complications in Burn and Toxic Epidermal Necrolysis (TENS) Patients

Inflammatory Response | Deep Vein Thrombosis | Multi Organ Failure | Nosocomial Infection

United States
Atara Biotherapeutics
Merck Sharp & Dohme LLC

Terminated

Tabelecleucel in Combination With Pembrolizumab in Subjects With Epstein-Barr Virus-associated Nasopharyngeal Carcinoma (EBV+ NPC)

Nasopharyngeal Carcinoma | Nasopharyngeal Neoplasms | Epstein-Barr Virus Infections | Epstein-Barr Viraemia | Epstein-Barr Virus-associated Nasopharyngeal Carcinoma (EBV+ NPC)

United States
Fakultas Kedokteran Universitas Indonesia

Unknown

Zinc Supplementation on Very Low Birth Weight Infant

Enterocolitis, Necrotizing | Retinopathy of Prematurity | Bronchopulmonary Dysplasia | Early-Onset Sepses, Neonatal | Small for Gestational Age Infant | Periventricular Haemorrhage Neonatal
University of Rhode Island
National Institute of Nursing Research (NINR); Thrasher Research Fund

Completed

Effects of Delayed Cord Clamping in Very Low Birth Weight Infants

Necrotizing Enterocolitis | Intraventricular Hemorrhage | Bronchopulmonary Dysplasia | Motor Skills Disorders | Late Onset Neonatal Sepsis

United States
Columbia University
New York University

Completed

Restoring Energy With Sub-symptom Threshold Optimized Rehabilitation Exercise for Long COVID (RESToRE)

Long Covid19 | Exercise Intolerance | Riboflavin-Responsive

United States
University of Maryland, Baltimore
University of Maryland, College Park

Terminated

Trial Of Cisplatin And KML-001 in Platinum Responsive Malignancies (0805GCC)

Non-Small Cell Lung Cancer, Small Cell Lung Cancer | Platinum Responsive Malignancies

United States
National Taiwan University Hospital

Recruiting

HCV Reinfection in in HIV/HCV-coinfected Patients Achieving SVR by Antiviral Therapy

Hepatitis C Virus Infection | Hepatitis C Virus Infection, Response to Therapy of | Human Immunodeficiency Virus (HIV) Coinfection

Taiwan
NYU Langone Health
Daxor Corporation

Completed

Blood Volume Assessment in COVID-19 and Bacterial Sepsis (BVAC19)

Covid19 | Bacterial Infections | Acute Respiratory Distress Syndrome | Bacterial Sepsis

United States
Rigshospitalet, Denmark
Statens Serum Institut

Completed

Host RNA Expression Profiles and Protein Biomarkers in Neonatal Herpes Simplex Virus Infection

Neonatal Infection | Viral Infection | Neonatal Sepsis | Neonatal Death | Herpes Simplex Virus Infection | Newborn; Infection | Neonatal Herpes Simplex Infection | Neonatal HSV Infection

Denmark
Institut de cancérologie Strasbourg Europe
LEAF4Life, Inc.

Completed

A Study of Liposomal Trans Crocetin, LEAF-4L6715, in Patients With Acute Respiratory Distress Syndrome Due to COVID-19, Sepsis or Other Causes

Acute Respiratory Distress Syndrome | COVID19, Sepsis or Other Causes

France
Loma Linda University

Withdrawn

Tazemetostat for the Treatment of Moderate to Severe COVID-19 Infection (IST)

Cytokine Release Syndrome | COVID-19 Acute Respiratory Distress Syndrome
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Chlorhexidine Gluconate Cleansing in Preventing Central Line Associated Bloodstream Infection and Acquisition of Multi-drug Resistant Organisms in Younger Patients With Cancer or Undergoing Donor Stem Cell Transplant

Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Malignant Neoplasm | Bacterial Infection | Myeloid Neoplasm | Benign Neoplasm | Methicillin-Resistant Staphylococcus Aureus Infection

United States, Canada, Puerto Rico
Hospital Clinic of Barcelona

Unknown

Dexmedetomidine to Improve Outcomes of ARDS in Critical Care COVID-19 Patients (COVID-DEX)

Inflammation | Acute Respiratory Distress Syndrome | Dexmedetomidine | Cytokine Storm | Delirium, Emergence
Hannah Brown Amoakoh
University of Ghana; Ghana Health Services

Completed

Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in Ghana (Accelerate)

Eclampsia | Asphyxia | Neonatal Jaundice | Postpartum Haemorrhage | Pre-eclampsia | Maternal Death | Neonatal Sepsis | Neonatal Death | Pregnancy Induced Hypertension | Puerperal Sepsis

Ghana
Hamad Medical Corporation

Unknown

Effect of Taurine on Glycemic Control in Type I and Type II Diabetic Patients

it is a Group of Metabolic Diseases in | Which a Person Has High Blood Sugar, Either | Because the Body Does Not Produce Enough Insulin, | or Because Cells do Not Respond to the Insulin That | is Produced.
Masonic Cancer Center, University of Minnesota

Terminated

Monitoring of Immune and Microbial Reconstitution in (HCT) and Novel Immunotherapies

Cytokine Release Syndrome | Immune and Microbial Reconstitution | Systemic Viral Infection | Acute-graft-versus-host Disease | Chronic Graft-versus-host-disease | Recurrent Malignancy | Allogenic Related Donors | Cell Therapy/Immunotherapy Patients

United States
University College, London
Ministry of Health and Child Welfare, Zimbabwe; Biomedical Research and Training... and other collaborators

Recruiting

Evaluating the NeoTree in Malawi and Zimbabwe

Neonatal Encephalopathy | Prematurity | Neonatal Seizure | Neonatal Jaundice | Neonatal Sepsis | Neonatal Death | Neonatal Respiratory Failure | Neonatal Hypoglycemia | Neonatal Disorder | Neonatal Hypothermia

Zimbabwe, Malawi
University of Florida
Society for Pediatric Dermatology; Eunice Kennedy Shriver National Institute...

Completed

Antibiotic "Dysbiosis" in Preterm Infants

Bacteremia | Enterocolitis, Necrotizing | Intraventricular Hemorrhage | Chronic Lung Disease | Bronchopulmonary Dysplasia | Periventricular Leukomalacia | Ileal Perforation

United States
Alexandria University
Science and Technology Development Fund (STDF), ,Egypt

Completed

Safety and Effectiveness of Cyclosporin in the Management of COVID19 ARDS Patients in Alexandria University Hospital

Pulmonary Fibrosis | Cytokine Release Syndrome | COVID-19 Acute Respiratory Distress Syndrome

Egypt
Polish Lymphoma Research Group
AstraZeneca

Active, not recruiting

Acalabrutinib in CLL and MCL Patients Subjected to Allogeneic Hematopoietic Stem Cell Transplantation (alloSCT) (ACALLO)

Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Adverse Event | Chronic Graft-versus-host-disease | Response Rate

Poland
Vitio Medical S.L.
Hospital Universitario de Navarra; NAVARRABIOMED

Completed

Continuous Temperature Telemonitoring of Patients With COVID-19 and Other Infectious Diseases in Hospital at Home Using Viture (Viture)

COVID-19 | Infectious Disease | Bacteremia | Cellulitis | Respiratory Infection | Tract Infection, Urinary

Spain
Achaogen, Inc.
Department of Health and Human Services

Completed

A Study of Plazomicin Compared With Colistin in Patients With Infection Due to Carbapenem-Resistant Enterobacteriaceae (CRE) (CARE)

Bloodstream Infections (BSI) Due to CRE | Hospital-Acquired Bacterial Pneumonia (HABP) Due to CRE | Ventilator-Associated Bacterial Pneumonia (VABP) Due to CRE | Complicated Urinary Tract Infection (cUTI) Due to CRE | Acute Pyelonephritis (AP) Due to CRE
Shaare Zedek Medical Center

Completed

Procalcitonin Level and Kinetics in Children With Bacterial Infections

Bacterial Infections | Bacteremia | Cellulitis | Urinary Tract Infection | Meningitis | Osteomyelitis | Septic Arthritis | Mastoiditis | Lobar Pneumonia

Israel
Princess Anna Mazowiecka Hospital, Warsaw, Poland
Medical University of Warsaw

Not yet recruiting

The High Initial Dose of Monitored Vitamin D Supplementation in Preterm Infants. (HIDVID)

Nephrolithiasis | Vitamin D Deficiency | Metabolic Bone Disease | Osteopenia of Prematurity | Late-Onset Neonatal Sepsis

Poland
Pfizer

Completed

Efficacy and Safety of CAZ-AVI in the Treatment of Infections Due to Carbapenem-resistant G- Pathogens in Chinese Adults

Bacteremia | Urinary Tract Infection | Intra-abdominal Infection | Hospital Acquired Pneumonia | Acute Pyelonephritis | Ventilator-associated Pneumonia

China
Dr Caeymaex Laurence
Ministry of Health, France; Paris 12 Val de Marne University

Completed

SEPREVEN: a Stepped-wedge Randomised Controlled Trial (SEPREVEN)

Nosocomial Pneumonia | Extravasation Injury | Skin Lesion | Intubation Complication | Intensive Care Units, Neonatal | Misadventures to Patients During Surgical and Medical Care | Catheter-related Bloodstream Infection (CRBSI) Nos | Quality of Healthcare | Ventilator Adverse Event | Immature Newborn | Nasal... and other conditions

France
Hospital Universitario Virgen Macarena
Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

Enrolling by invitation

Clinical Outcomes in Patients With Infection by Resistant Microorganism

Pneumonia | Staphylococcus Aureus | Urinary Tract Infections | Surgical Site Infection | Escherichia Coli | Bloodstream Infection | Acinetobacter Infections | Pseudomonas Aeruginosa | Skin Infection | Klebsiella Pneumonia | Enterococcus Faecium Infection

Spain
Uppsala University

Recruiting

Mechanisms for Organ Dysfunction in Covid-19 (UMODCOVID19)

COVID-19 | Septic Shock | Acute Kidney Injury | Acute Respiratory Distress Syndrome | Organ Dysfunction Syndrome, Multiple | Organ Dysfunction Syndrome Sepsis

Sweden
KU Leuven
Research Foundation Flanders; National Institute for Health and Disability...

Completed

Optimising Diagnosis and Antibiotic Prescribing for Acutely Ill Children in Primary Care (ERNIE2)

Pneumonia | Sepsis | Abscess | Cellulitis | Meningitis | Osteomyelitis | Complicated Urinary Tract Infection | Bacteraemia | Gastro-enteritis With Dehydration | Viral Respiratory Infection Complicated With Hypoxia

Belgium
Infectopharm Arzneimittel GmbH
INPADS GmbH; Dr. Oestreich + Partner GmbH

Recruiting

Fosfomycin i.v. for Treatment of Severely Infected Patients (FORTRESS)

Respiratory Tract Infections | Sepsis | Encephalitis | Bacterial Infections | Intraabdominal Infections | Bacteremia | Skin Diseases, Bacterial | Pneumonia, Bacterial | Urinary Tract Infections | Meningitis, Bacterial | Central Nervous System Bacterial Infections | Soft Tissue Infections | Endocarditis, Bacterial | Bone Diseases, Infectious and other conditions

Germany, Austria, Greece, Italy, United Kingdom
Shionogi

Completed

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Cefiderocol in Hospitalized Pediatric Participants

Sepsis | Gram-negative Bacterial Infections | Bloodstream Infections (BSI) | Complicated Intra-abdominal Infection (cIAI) | Hospital Acquired Pneumonia (HAP) | Ventilator-acquired Pneumonia | Complicated Urinary Tract Infection (cUTI)

Spain, Belgium, Latvia, Russian Federation, Estonia, Georgia, Hungary, Thailand, Ukraine
Washington University School of Medicine

Active, not recruiting

Congenital Heart Anomaly Risk in Maternal Enteroviral Infection and Diabetes (CHARMED)

Heart Diseases | Virus Diseases | Diabetes Mellitus, Type 2 | Diabetes Mellitus | Diabetes | Diabetes Mellitus, Type 1 | Enterovirus Infections | Pregnancy Complications | Heart Defects, Congenital | Viremia | Congenital Heart Disease | Pregnancy in Diabetic | Enterovirus | Prenatal Infection | Prenatal

United States
Croatian Society for Organ Support
Clinical Hospital Centre Zagreb

Enrolling by invitation

Registry for Hemoperfusion of Covid-19 ICU Patients (HERICC)

Systemic Inflammatory Response Syndrome | Critical Illness | Multi Organ Failure | COVID-19 Acute Respiratory Distress Syndrome | Viral Disease | AKI - Acute Kidney Injury

Croatia
M.D. Anderson Cancer Center

Active, not recruiting

Combination Chemotherapy and Ponatinib Hydrochloride in Treating Patients With Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Philadelphia Chromosome Positive | B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 | Untreated Adult Acute Lymphoblastic Leukemia | Accelerated Phase Chronic Myelogenous Leukemia,... and other conditions

United States
PhaseBio Pharmaceuticals Inc.

Terminated

Pemziviptadil (PB1046), a Long-acting, Sustained Release Human VIP Analogue, Intended to Provide Clinical Improvement to Hospitalized COVID-19 Patients at High Risk for Rapid Clinical Deterioration and Acute Respiratory Distress Syndrome (ARDS). (VANGARD)

Pneumonia | Respiratory Failure | Respiratory Insufficiency | COVID 19 | Acute Respiratory Distress Syndrome | SARS-CoV-2 | Coronavirus | Cytokine Storm | Pulmonary Edema | Cardiac Event | Respiratory Complication | Cardiac Dysfunction | Hypoxemic Respiratory Failure | Hypoxic Respiratory Failure | Cardiac Failure | Cardiac... and other conditions

United States
Emory University
National Cancer Institute (NCI)

Withdrawn

Tocilizumab for the Treatment of Cytokine Release Syndrome in Patients With COVID-19 (SARS-CoV-2 Infection)

Coronary Artery Disease | Diabetes Mellitus | Chronic Obstructive Pulmonary Disease | Cerebrovascular Accident | Chronic Renal Failure | Malignant Neoplasm | SARS Coronavirus 2 Infection

United States
Wuhan University
Peking University; Pfizer

Unknown

Efficacy and Safety of Ziprasidone to Treat Depressive Symptoms in Patients With Schizophrenia

The Primary Evaluation is the Change From Baseline at End of Study for CDSS Total Scores. | The Secondary Efficacy Evaluations Include: MADRS, PANSS Total Scores and Subscales and Responder Rate; CGI-S and CGI-I Scales. | Safety Evaluations Include: Laboratory Test Abnormalities; BARS... and other conditions
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

CMV-MVA Triplex Vaccination of Stem Cell Donors in Preventing CMV Viremia in Participants With Allogeneic Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Hodgkin Lymphoma | Myelofibrosis | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Myelodysplastic/Myeloproliferative Neoplasm | Acute Myeloid Leukemia in Remission | Acute Lymphoblastic Leukemia in Remission | Cytomegalovirus... and other conditions

United States
Efficacy Care R&D Ltd
Memorial Hermann Hospital; CRG Medical, Inc.

Unknown

Postoperative Respiratory Abnormalities (AI-ARF)

Shock | Shock, Septic | Respiratory Failure | Respiratory Distress Syndrome | Shock, Cardiogenic | Acute Cardiac Failure | Acute Respiratory Failure | Acute Kidney Failure | Multi Organ Failure | Respiratory Arrest | Acute Respiratory Failure With Hypoxia | Acute Respiratory Failure Requiring Reintubation | Acute... and other conditions

United States

Clinical Trials on Analgesic Response

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