Clinical Trials on Anemia, Hemolytic, Autoimmune in South Africa

Total 997 results

Novo Nordisk A/S

Completed

Long Term Safety of Biphasic Insulin Aspart 30 in Juveniles With Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

South Africa
Foundation for Innovative New Diagnostics, Switzerland
University of Cape Town; The Leona M. and Harry B. Helmsley Charitable Trust; University of Pretoria

Recruiting

Use of Continuous Glucose Monitoring Devices Among People Living With Type 1 Diabetes in South Africa (ACCEDE)

Type 1 Diabetes

South Africa
Celgene

Recruiting

A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

Beta-thalassemia | Myelodysplastic Syndromes (MDS) | Myeloproliferative Neoplasm(MPN)-Associated Myelofibrosis

United States, Japan, Israel, United Kingdom, Turkey, Greece, France, Australia, Belgium, Bulgaria, Canada, Germany, Italy, Malaysia, Spain, Sweden, Taiwan, Thailand, Tunisia, China, Lebanon, Netherlands
Yaounde Central Hospital
University of Exeter; University of Yaounde 1; MRC/UVRI & LSHTM Uganda Research...

Recruiting

Characteristics of Young-onset Diabetes in Sub-Saharan Africa (YODA) Study (YODA)

Type 1 Diabetes | Diabetes, Autoimmune

Tanzania, Cameroon, South Africa, Uganda
Alexion Pharmaceuticals

Completed

Study Using Eculizumab in Transfusion Dependent Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients

Hemoglobinuria, Paroxysmal

United States, Australia, Belgium, Canada, Germany, Italy, United Kingdom, France, Ireland, Netherlands, Sweden, Switzerland
Alexion Pharmaceuticals

Completed

Extension Study of Eculizumab in Patients With Transfusion Dependent Paroxysmal Nocturnal Hemoglobinuria (PNH)

Paroxysmal Hemoglobinuria, Nocturnal

United States, Australia, Belgium, Canada, Germany, Italy, Spain, Sweden, United Kingdom, France, Ireland, Netherlands
Pharmacosmos A/S

Completed

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for the Treatment of Iron Deficiency Anemia (IDA)

Iron Deficiency Anemia | Iron Deficiency Anaemia

United States
Universitas Sriwijaya
Indonesia University

Completed

Local Culture-Based Nutrition Education Intervention on Iron Supplement Tablets (IST) Consumption Compliance in Female Adolescents at Ogan Komering Ilir Regency: A Quasi-Experimental Protocol Study

Anemia | Iron Deficiency Anemia

Indonesia
Ra Pharmaceuticals

Completed

Phase 2 Safety and Efficacy Study of Zilucoplan (RA101495) to Treat PNH Patients

Paroxysmal Nocturnal Hemoglobinuria (PNH)

United Kingdom, Australia, Canada, Denmark, Finland, Germany, Hungary, New Zealand
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Gastric Capsule Examination for Iron Deficiency Anaemia

Iron Deficiency Anemia

United Kingdom
United States Army Research Institute of Environmental...

Completed

An Iron-containing Food Product for the Prevention of Diminished Iron Status in Soldiers

Iron Deficiency Anemia | Iron Deficiency

United States
BioAge Labs, Inc.

Withdrawn

Study to Evaluate Efficacy and Safety of BGE-117 in Moderately to Severely Anemic Older Individuals After Major Hip Surgery

Acute Posthemorrhagic Anemia

Australia
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effect of a Single Dose of CNTO 136 (Sirukumab) on CYP450 Enzyme Activities After Subcutaneous Administration in Patients With Rheumatoid Arthritis

Arthritis, Rheumatoid

Germany, Korea, Republic of, South Africa, Moldova, Republic of
Hoffmann-La Roche
Chugai Pharmaceutical

Active, not recruiting

A Phase III Study Evaluating the Efficacy and Safety of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Not Previously Treated With Complement Inhibitors. (COMMODORE 2)

Paroxysmal Nocturnal Hemoglobinuria

Spain, Korea, Republic of, France, Sweden, Thailand, Malaysia, China, Turkey, Netherlands, Japan, Australia, United Kingdom, Germany, South Africa, Brazil, Romania, Argentina, Poland, Greece, Hong Kong, Lithuania, Mexico, Philippines, Portuga... and more
Hoffmann-La Roche

Recruiting

A First-in-Human Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7507062 in Participants With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus

United Kingdom, Spain, Germany, Poland, South Africa, Netherlands
Alexion

Completed

ALXN1210 Versus Eculizumab in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Eculizumab

Paroxysmal Nocturnal Hemoglobinuria (PNH)

United States, Korea, Republic of, Canada, France, Germany, Spain, United Kingdom, Japan, Australia, Italy, Netherlands
Pharmacosmos A/S

Completed

Iron Isomaltoside/Ferric Derisomaltose vs Iron Sucrose for Treatment of Iron Deficiency Anemia in Non-Dialysis-Dependent Chronic Kidney Disease

Chronic Kidney Disease | Iron Deficiency Anemia | Iron Deficiency Anaemia

United States
AMAG Pharmaceuticals, Inc.

Completed

A Trial Comparing Ferumoxytol With Iron Sucrose for the Treatment of Iron Deficiency Anemia

Iron Deficiency Anemia

Germany, Poland, United Kingdom, Australia, France, Hungary, Italy, Korea, Republic of, Latvia, Lithuania, Romania, South Africa, Spain, Ukraine
University of Cape Town

Completed

Study of Hip and Knee Arthroplasty in South Africa

Arthritis, Rheumatoid | Osteoarthritis, Knee | Osteoarthritis, Hip | Arthritis Knee | Arthritis of Hip

South Africa
GlaxoSmithKline
Quintiles, Inc.; ERT: Clinical Trial Technology Solutions; Q2 Solutions; HemoCue

Completed

Anemia Study in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat-Blood Pressure (ASCEND-BP)

Anaemia

United States
Novartis Pharmaceuticals

Recruiting

Single Arm, Open Label Trial With Iptacopan Treatment for 24 Weeks, in Patients on Stable Regimen of Anti-C5 Who Switch to Iptacopan. (APPULSE)

Paroxysmal Nocturnal Hemoglobinuria

France, Spain, Italy, Turkey, Germany, United States, Korea, Republic of, United Kingdom
Keros Therapeutics, Inc.

Recruiting

A Study to Evaluate the Safety and Preliminary Efficacy of a Response-guided Dose Titration of KER-047 in the Treatment of Functional IDA (Iron Deficiency Anemia).

Iron Deficiency Anemia

Australia, Israel, Romania
GlaxoSmithKline

Completed

GSK2018682 FTIH in Healthy Volunteers (P1A114070)

Multiple Sclerosis

Australia
Dr. Rosdiana Syakur
Hasanuddin University

Recruiting

The Effect Of Pumpkin Seed Extract Capsules On Nutritional Status and Haemoglobin Level in Pregnant Women.

Anemia During Pregnancy

Indonesia
Novo Nordisk A/S

Completed

Safety of Insulin Detemir Produced by a New Process as Measured by Antibody Formation in Subjects With Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

Germany, South Africa, Russian Federation, Former Serbia and Montenegro, North Macedonia
Novo Nordisk A/S

Completed

A Survey on Low Blod Sugar Among Insulin-treated Patients With Diabetes

Diabetes Mellitus, Type 2 | Diabetes | Diabetes Mellitus, Type 1

Turkey, Egypt, Philippines, United Arab Emirates, Bangladesh, Colombia, Singapore, South Africa
BioAge Labs, Inc.

Withdrawn

Study to Evaluate Efficacy and Safety of BGE-117 in the Treatment of Anemia of Aging

Anemia

Australia
Novartis Pharmaceuticals

Recruiting

Long-term Safety and Tolerability of Iptacopan in Patients With Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria

United States, Korea, Republic of, Singapore, Taiwan, Italy, Turkey, France, Germany, Malaysia, Lithuania, Netherlands, United Kingdom, Japan, Czechia, Spain, China, Brazil
American Regent, Inc.

Completed

Can Iron Lessen Anemia Due to Cancer and Chemotherapy: A Study to Investigate the Efficacy and Safety of Injectafer® (IRON CLAD)

Cancer and Chemotherapy Related Anemia

United States
GlaxoSmithKline

Completed

Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat-in Incident Dialysis (ASCEND-ID)

Anaemia

United States, Korea, Republic of, Argentina, Spain, Australia, Canada, Russian Federation, United Kingdom, Malaysia, Italy, Poland, Germany, India, Mexico, South Africa
GlaxoSmithKline

Completed

Assessment of Repeat Ascending Doses of GSK2018682 in Healthy Volunteers (P1A114347)

Multiple Sclerosis, Relapsing-Remitting

Australia
Novo Nordisk A/S

Completed

Frequency of Hypoglycaemic Episodes During Treatment With Insulin Detemir in Well Controlled Subjects With Type 1 Diabetes

Diabetes | Diabetes Mellitus, Type 1

Denmark, Croatia, Australia, South Africa, Italy, Sweden
Pfenex, Inc

Completed

Comparison Study of PF530 and Betaferon in Healthy Subjects

Multiple Sclerosis

Australia
GlaxoSmithKline

Completed

A Placebo-controlled Study to Investigate the Safety, and Pharmacokinetics of Oral GSK626616AC in Healthy Subjects

Healthy Subjects | Anaemia

Australia
Hoffmann-La Roche
Chugai Pharmaceutical

Recruiting

A Study Evaluating The Safety, Pharmacokinetics, and Efficacy Of Crovalimab Versus Eculizumab In Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Complement Inhibitors (COMMODORE 1)

Paroxysmal Nocturnal Hemoglobinuria

United States, Korea, Republic of, Spain, Germany, Estonia, Japan, Colombia, Saudi Arabia, Turkey, Brazil, France, Greece, Poland, Taiwan, Netherlands, Italy, Australia, Sweden, Singapore, Portugal, Hungary, Belgium, Canada, Czechia, Hong... and more
GeNeuro Australia PTY Ltd

Completed

Single Ascending Doses Study With GNbAC1 in Healthy Male Volunteers

Multiple Sclerosis

Australia
GlaxoSmithKline

Completed

GSK239512 DDI Study

Multiple Sclerosis

Australia
GlaxoSmithKline

Completed

Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Single Oral Doses of GSK1278863A in Healthy Subjects

Anaemia

Australia
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Ischemic Preconditioning, Exercise Tolerance and Multiple Sclerosis

Multiple Sclerosis

United Kingdom
Sheffield Hallam University
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Feasibility and Acceptability of Orthotic Shorts for People With Multiple Sclerosis

Multiple Sclerosis

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Sheffield Hallam University

Completed

High Intensity Interval Training for People With Mild Multiple Sclerosis: A Feasibility Study (HIIT-MS)

Multiple Sclerosis

United Kingdom
GlaxoSmithKline

Completed

Healthy Volunteer Study Using 3 Different Formulations of Firategrast

Multiple Sclerosis, Relapsing-Remitting

Australia
Sheffield Teaching Hospitals NHS Foundation Trust
JP Moulton Charitable Foundation

Completed

RIPC on Activity, Fatigue and Gait in MS (MSIPC-2)

Multiple Sclerosis

United Kingdom
GlaxoSmithKline

Completed

Healthy Volunteer Pilot Study Using 3 Types of Modified Release Formulations of Firategrast to Investigate How Quickly Absorption From the Digestive System Takes Place.

Multiple Sclerosis, Relapsing-Remitting

Australia
FibroGen

Completed

A Randomized Study of the Safety and Efficacy of FG-2216 in Subjects With Renal Anemia Not Requiring Dialysis and Not Receiving Recombinant Human Erythropoietin

Renal Anemia

United States
AMAG Pharmaceuticals, Inc.

Completed

A Phase III Safety Study of Ferumoxytol Compared to Ferric Carboxymaltose for the Treatment of Iron Deficiency Anemia (IDA)

Iron Deficiency Anemia

United States, Canada, Hungary, Latvia, Poland, Lithuania, Puerto Rico
Sheffield Teaching Hospitals NHS Foundation Trust

Recruiting

Acceptability of Exoskeleton Assisted Walking for Persons With Mobility Issues Due to Multiple Sclerosis (ExoMS)

Pathologic Processes | Multiple Sclerosis | Sclerosis | Demyelinating Autoimmune Diseases, CNS | Autoimmune Diseases of the Nervous System | Autoimmune Diseases

United Kingdom
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of Patients With Pure Red Cell Aplasia Associated With Recombinant Human Erythropoietin Treatment

Pure Red-cell Aplasia

United Kingdom, Sweden, South Africa, Brazil, Canada, Germany, Norway, Thailand
Leiden University Medical Center

Recruiting

The TAPS Trial - Fetoscopic Laser Surgery for Twin Anemia Polycythemia Sequence

Twin Anemia Polycythemia Sequence

United States, Italy, Netherlands, Spain, Sweden
AMAG Pharmaceuticals, Inc.

Completed

A Trial of Ferumoxytol for the Episodic Treatment of Iron Deficiency Anemia

Iron Deficiency Anemia

United States, Canada, Hungary, India, Latvia, Poland

Clinical Trials on Anemia, Hemolytic, Autoimmune in South Africa

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