Clinical Trials on Anesthesia, General

Total 259884 results

National Cancer Institute (NCI)

Terminated

EF5 to Evaluate Tumor Hypoxia in Patients With High-Grade Soft Tissue Sarcoma or Mouth Cancer

Stage III Adult Soft Tissue Sarcoma | Stage I Adult Soft Tissue Sarcoma | Stage II Adult Soft Tissue Sarcoma | Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage II Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity

United States
University Hospital, Toulouse

Completed

The RITAI Cohort: An Observational Study on Rituximab Off-label Use for Auto-immune Disorders (RITAI)

Cryoglobulinemia | Cold Agglutinin Disease | Pemphigus | Auto-immune Thrombocytopenic Purpura | Hemolytic Auto-immune Anaemia

France
Institut Paoli-Calmettes

Completed

Fludarabine, Busulfan, and Antilymphocyte Globulin Followed by Donor Stem Cell Transplant in Treating Older Patients With Hematological Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

France
Fred Hutchinson Cancer Center

Completed

Donor Bone Marrow Transplant in Treating Young Patients With Cancer or a Non-Cancerous Disease

Sarcoma | Lymphoma | Kidney Cancer | Myelodysplastic Syndromes | Leukemia | Neuroblastoma

United States
University of Arizona
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Therapy in Treating Patients With Advanced Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous/Nonmalignant Condition

United States
PETHEMA Foundation

Completed

LINFOTARGAM: Treatment With Chemotherapy Plus Rituximab and Highly Active Antiretroviral Therapy in Patients With Diffuse Large B Cell Lymphoma and Infection With the Human Immunodeficiency Virus (HIV) (LINFOTARGAM)

HIV Infections | Diffuse Large B Cell Lymphoma

Spain
Massachusetts General Hospital

Terminated

Study to Identify Markers of Insulin Resistance During Growth Hormone Treatment for Short Stature

Turner Syndrome | Idiopathic Short Stature

United States
National Cancer Institute (NCI)

Completed

The Effect of Oral Candidiasis on the Speech Production, Feeding Skills, and Self-Concept of Children and Adolescents With Symptomatic HIV Infection

HIV Infections | Speech Disorders | Candidiasis, Oral | Eating Disorders

United States
Masonic Cancer Center, University of Minnesota

Recruiting

MT2013-31: Allo HCT for Metabolic Disorders and Severe Osteopetrosis

Hurler Syndrome | Sphingolipidoses | Peroxisomal Disorders | Metachromatic Leukodystrophy | Alpha-Mannosidosis | Hunter Syndrome | Mucopolysaccharidosis Disorders | Maroteaux Lamy Syndrome | Sly Syndrome | Fucosidosis | Aspartylglucosaminuria | Glycoprotein Metabolic Disorders | Recessive Leukodystrophies | Globoid... and other conditions

United States
New York Medical College

Completed

Human Placental-Derived Stem Cell Transplantation (HPDSC)

Mucopolysaccharidosis I | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Niemann-Pick Disease | Mucopolysaccharidosis VI | Wolman Disease | Adrenoleukodystrophy | Batten Disease | Metachromatic Leukodystrophy | Diamond-Blackfan Anemia | Severe Aplastic Anemia | Fucosidosis | Gaucher... and other conditions

United States
Masonic Cancer Center, University of Minnesota

Completed

Auto Transplant for High Risk or Relapsed Solid or CNS Tumors

Soft Tissue Sarcoma | Medulloblastoma | Retinoblastoma | Rhabdomyosarcoma | Hepatoblastoma | Primary Malignant Brain Neoplasms | CNS Tumors | Germ Cell Tumors | Ewing's Family Tumors | Renal Tumors | Supra-tentorial Primative Neuro-Ectodermal Tumor (PNET) | Atypical Teratoid/Rhabdoid Tumor (AT/RT)

United States
Alaunos Therapeutics

Unknown

Intravenous Palifosfamide-tris in Combination With Etoposide and Carboplatin in Patients With Malignancies

Cancer | Small Cell Lung Cancer | Ovarian Cancer | Thymoma | Osteosarcoma | Non Small Cell Lung Cancer | Malignancy | Testicular Cancer

United States
Université de Sherbrooke
Canadian Institutes of Health Research (CIHR); Western University, Canada; Agence...

Completed

Patient-Centred Innovations for Persons With Multimorbidity - Quebec (PACEinMM-QC)

Depression | Heart Failure | Stroke | Hypertension | Cardiovascular Disease | Diabetes | Ulcer | Cancer | Arthritis | Rheumatoid Arthritis | Musculoskeletal Pain | Asthma | Gastroesophageal Reflux | Dementia | Anxiety | HIV | Crohn's Disease | Osteoporosis | Ulcerative Colitis | Chronic Obstructive Pulmonary Disease (COPD) | Hyperlipi... and other conditions

Canada
National Cancer Institute (NCI)
NRG Oncology

Completed

Intraperitoneal Bortezomib and Carboplatin in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Ovarian Clear Cell Cystadenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Seromucinous Carcinoma | Ovarian Serous Cystadenocarcinoma | Ovarian Clear Cell Adenocarcinoma | Ovarian Mucinous... and other conditions

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); Memorial Sloan Kettering Cancer Center; American...

Active, not recruiting

Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain Tumors

Glioblastoma Multiforme | Medulloblastoma | Low-Grade Astrocytoma, Nos | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Pilocytic Astrocytoma | Pineoblastoma | Supratentorial Primitive Neuroectodermal Tumor | Atypical Teratoid/Rhabdoid Tumor | Choroid Plexus Carcinoma | High-grade Astrocytoma NOS | CNS... and other conditions

United States
Rush University Medical Center
National Institute on Aging (NIA)

Recruiting

PERSEVERE: Peer Mentor Support and Caregiver Education in Lewy Body Dementia

Lewy Body Disease | Dementia With Lewy Bodies | Lewy Body Dementia | Parkinson Disease Dementia

United States
VA Office of Research and Development

Not yet recruiting

Personalized Approach Bias Modification in Heavy Drinking Veterans With Mild to Moderate Traumatic Brain Injury (TABM)

Alcohol Use Disorder | Mild-Moderate Traumatic Brain Injury

United States
Xinhua Hospital, Shanghai Jiao Tong University...
Shanghai Vitalgen BioPharma Co., Ltd.

Recruiting

An Exploratory Clinical Trial of VGN-R08b in Patients With Type II Gaucher Disease

Type II Gaucher Disease

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Social-cognitive Functioning: Validation of a New Neuropsychological Test (REALSOCOG)

Alzheimer's Disease (AD) | Lewy Body Dementia (LBD) | Frontotemporal Degeneration (FTD)

France
Prevail Therapeutics
Eli Lilly and Company

Recruiting

A Clinical Trial of PR001 (LY3884961) in Patients With Peripheral Manifestations of Gaucher Disease (PROCEED)

Gaucher Disease | Gaucher Disease, Type 1

United States, Spain, Germany
University of Cambridge
Cambridgeshire and Peterborough NHS Foundation Trust; The Gianna Angelopoulos... and other collaborators

Not yet recruiting

Optical Neuroimaging and Cognition (ONAC)

Alzheimer Disease | Mild Cognitive Impairment | Dementia With Lewy Bodies
Shaare Zedek Medical Center

Recruiting

Prodromal Parkinsonian Features in GBA1 Mutation Carriers

Healthy | Gaucher Disease, Type 1

Israel
Second Affiliated Hospital, School of Medicine,...

Recruiting

PD-1 Antibody Combined Neoadjuvant Chemotherapy for Ovarian Cancer

Ovarian Cancer | Neoadjuvant Chemotherapy | Anti-PD-1 | Neoadjuvant Immunotherapy

China
Serhat Gumrukcu, MD PhD
Frida Therapeutics LLC

Recruiting

Clinical Specimen Collection From Pompe Disease Patients

Pompe Disease

United States
Columbia University

Recruiting

Autoimmune Features of Neurodegenerative Disorders

Parkinson Disease | Alzheimer Disease | Mild Cognitive Impairment

United States
Rabin Medical Center

Recruiting

Effect of Nutritional Formula Supplementation on Growth Rate of Growth Hormone (GH) Treated Children With Growth Hormone Deficiency (GHD) After the Second Year of Therapy

Growth Retardation | IGHD - Isolated Growth Hormone Deficiency

Israel
Maimonides Medical Center

Active, not recruiting

Oral Aspirin + Ketamine as Adjunct to Oral Antidepressant Therapy for Depression

Analgesia | Depressive Symptoms | Major Depressive Disorder | Treatment Resistant Depression | Ketamine | Physiological Effects of Drugs | Analgesics, Non-Narcotic | Peripheral Nervous System Agents | Central Nervous System Depressants | Neurotransmitter Agents | Sensory System Agents | Anti-Inflammatory Agents and other conditions

United States
Prevail Therapeutics
Eli Lilly and Company

Active, not recruiting

Phase 1/2 Clinical Trial of PR001 in Infants With Type 2 Gaucher Disease (PROVIDE)

Gaucher Disease, Type 2

United States, United Kingdom
Genzyme, a Sanofi Company

Active, not recruiting

Study to Evaluate Efficacy and Safety in Chinese Patients With Late Onset Pompe Disease With Alglucosidase Alfa Treatmen (APOLLO-LOPD)

Pompe's Disease

China
AVROBIO

Terminated

Lentiviral Vector Gene Therapy - The Guard1 Trial of AVR-RD-02 for Subjects With Type 1 Gaucher Disease

Gaucher Disease

United States, Canada
Sanofi

Completed

A Study to Evaluate Pharmacokinetic Parameters and Safety of Eliglustat Absorption Through the Mouth (Acronym)

Gaucher's Disease

United States
Hadassah Medical Organization

Completed

A Second-generation AI Based Therapeutic Regimen in Patients With Gaucher Disease Treated With Enzyme Replacement Therapy.

Gaucher Disease Type 1

Israel
AVROBIO

Terminated

A Long-Term Follow-up Study of Subjects With Gaucher Disease Who Previously Received AVR-RD-02

Type 1 Gaucher Disease

United States, Canada
Amicus Therapeutics

Available

Expanded Access for ATB200/AT2221 for the Treatment of Pompe Disease

Pompe Disease
Duke University

Completed

Adaptive Pet Study

Head and Neck Cancers | Lung and Esophagus Cancers | Anal, Cervix, Vulvar, Vaginal, and Endometrium Cancers

United States
Baylor College of Medicine
Rare Diseases Clinical Research Network; Neogenis Laboratories

Completed

Nitric Oxide Supplementation on Neurocognitive Functions in Patients With ASLD

Urea Cycle Disorders, Inborn | Urea Cycle Disorder | Argininosuccinic Aciduria | Argininosuccinate Lyase Deficiency

United States
Hospices Civils de Lyon

Completed

Low Grade Serous Ovarian Carcinoma and Uterine Involvement : Should Hysterectomy be the Rule (LOGYST)

Serous Ovarian Carcinoma | Low Grade Serous Ovarian Carcinoma

France
Shaare Zedek Medical Center

Completed

Ambroxol Therapy for Patients With Type 1 Gaucher Disease and Suboptimal Response to Enzyme Replacement Therapy

Gaucher Disease, Type 1

Israel
Ari Zimran
Pfizer

Active, not recruiting

A Multicenter, Safety and Efficacy Study of Taliglucerase Alfa in Subjects With Type 3 Gaucher Disease

Gaucher Disease, Type 3

Israel, Turkey, India
Universiteit Antwerpen
Amsterdam UMC, location VUmc; Novosanis NV; Self-screen B.V.

Completed

CASUS: Validation for Detection of Precursor Lesions (CASUS-WP4)

Cervical Cancer | Cervical Intraepithelial Neoplasia | HPV-Related Cervical Carcinoma | Urine | Human Papilloma Virus

Belgium
University of Manchester
Northern Care Alliance NHS Foundation Trust

Completed

Neurostimulation for Dysphagia in Parkinson's Disease

Brain Diseases | Parkinson Disease | Dysphagia | Swallowing Disorder.Other Specified

United Kingdom
AstraZeneca

Completed

Olaparib Tablets as a Treatment for Ovarian Cancer Subjects With Different HRD Tumor Status

Relapsed Ovarian Cancer, BRCA Mutation, Platinum Sensitivity

United States, Canada
University of Southern California
National Institute on Aging (NIA); Northern California Institute of Research... and other collaborators

Completed

Alzheimer's Disease Neuroimaging Initiative 2 (ADNI2)

Mild Cognitive Impairment (MCI) | Alzheimer's Disease (AD) | Significant Memory Concern (SMC) | Early Mild Cognitive Impairment (EMCI) | Late Mild Cognitive Impairment (LMCI)

United States, Canada
Duke University

Completed

Lingual Muscle Training in Late-Onset Pompe Disease (LOPD)

Glycogen Storage Disease

United States
CEN Biotech
Takeda; BioClinica, Inc.

Completed

Retrospective and Prospective Observational Study of MRI Changes in Bone and Visceral Lesions of Patients With Type 1 Gaucher Disease Treated With VPRIV® (Velaglucerase Alfa) (EIROS)

MRI | Gaucher Disease, Type 1

France
Shire

Completed

An Open-Label Extension Study of GA-GCB ERT in Patients With Type 1 Gaucher Disease

Gaucher Disease, Type 1

United States, Israel, Argentina, India, Korea, Republic of, Paraguay, Poland, Russian Federation, Spain, Tunisia, United Kingdom
Shire

Completed

Study of GA-GCB Enzyme Replacement Therapy in Type 1 Gaucher Disease Patients Previously Treated With Imiglucerase

Gaucher Disease

United States, Israel, United Kingdom, Poland, Spain
CENTOGENE GmbH Rostock

Completed

Lyso-Gb1 as a Long-term Prognostic Biomarker in Gaucher Disease (LYSO-PROOF)

Lysosomal Storage Diseases | Sphingolipidoses | Gaucher Disease

Albania, Greece, India, Israel, Morocco, Pakistan, Spain
Shire

Approved for marketing

Treatment Protocol of Velaglucerase Alfa for Patients With Type 1 Gaucher Disease

Gaucher Disease, Type 1

United States
Lei Li

Unknown

Immunohistochemical Staining of p16 for the Screening of Cervical Cancer

Cervical Intraepithelial Neoplasia | Cervical Cancer Screening | Histology | p16 Protein | Cytology | High-risk Human Papillomavirus | Diagnostic Accuracy

China

Clinical Trials on Anesthesia, General

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