Clinical Trials on Antibiotic Resistant Infection in South Africa

Total 3577 results

ViiV Healthcare
Pfizer

Terminated

Comparative Trial Of Maraviroc Versus Emtricitabine/Tenofovir Both With Darunavir/Ritonavir In Antiretroviral-Naive Patients Infected With CCR5 Tropic HIV 1 (MODERN)

HIV-1

United States, Netherlands, Spain, Puerto Rico, Canada, Australia, Germany, Sweden, Poland, Portugal, Switzerland, France, Denmark, Italy, Belgium, United Kingdom, Hungary, Austria, Finland
Sunovion

Completed

A Safety and Efficacy Study of Ciclesonide Nasal Aerosol in Subjects 6-11 Years With Seasonal Allergic Rhinitis (SAR)

Seasonal Allergic Rhinitis

United States
Procter and Gamble

Completed

Study of Oral PG-116800 Following a Heart Attack

Myocardial Infarction | Heart Failure | Heart Enlargement

United States, Canada, Poland
Amgen

Completed

Efficacy, Safety, and Tolerability Study of Apremilast to Treat Early Oligoarticular Psoriatic Arthritis. (FOREMOST)

Arthritis, Psoriatic

United States, Spain, Netherlands, Canada, France, Russian Federation, Belgium, Austria, Germany, Italy, United Kingdom
ModernaTX, Inc.

Active, not recruiting

A Study of mRNA-1345 Vaccine Targeting Respiratory Syncytial Virus (RSV) in Adults ≥50 Years of Age (RSVictory)

Respiratory Syncytial Virus

United States
X4 Pharmaceuticals

Active, not recruiting

Efficacy and Safety Study of Mavorixafor in Participants With Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) Syndrome

WHIM Syndrome

United States, Denmark, Australia, Austria, France, Hungary, Israel, Italy, Korea, Republic of, Netherlands, Russian Federation, Spain, Turkey
Helsinn Therapeutics (U.S.), Inc

Completed

Clinical Study Assessing Outcomes, Adverse Events, Treatment Patterns, and Quality of Life in Patients Diagnosed With Mycosis Fungoides Cutaneous T-cell Lymphoma (PROVe)

Mycosis Fungoides

United States
Lyra Therapeutics

Recruiting

Efficacy and Safety of LYR-210 for the Treatment of Chronic Rhinosinusitis in Adults (ENLIGHTEN 2)

Chronic Sinusitis | Chronic Rhinosinusitis (Diagnosis)

United States, Poland, Bulgaria, Belgium, Germany, Hungary
Intersect ENT

Completed

S8 Sinus Implant in Chronic Sinusitis Patients With Recurrent Nasal Polyps (RESOLVE_II)

Chronic Sinusitis | Nasal Polyposis

United States
Novartis Pharmaceuticals

Terminated

A Phase 2 Study of NIR178 in Combination With PDR001 in Patients With Solid Tumors and Non-Hodgkin Lymphoma

Melanoma | Head and Neck Cancer | Pancreatic Cancer | Urothelial Cancer | NSCLC, Non Small Cell Lung Cancer | RCC, Renal Cell Cancer | DLBCL, Diffused Large B Cell Lymphoma | MSS, Microsatellite Stable Colon Cancer | TNBC, Triple Negative Breast Cancer | mCRPC, Metastatic Castration Resistant Prostate...

Belgium, Italy, Taiwan, Germany, Spain, United States, Argentina, Australia, Austria, Czechia, France, Japan, Netherlands, Switzerland, Singapore
Novartis Pharmaceuticals

Completed

16-week Efficacy and 2-year Safety, Tolerability and Efficacy of Secukinumab in Participants With Active Psoriatic Arthritis (FUTURE 4)

Arthritis, Psoriatic

United States, Italy, Germany, Australia, Belgium, Poland, Bulgaria, Russian Federation, Czechia, Canada, France, Sweden, United Kingdom
UCB Biopharma SRL

Completed

A Study to Evaluate the Long-Term Safety and Efficacy of Bimekizumab in Subjects With Psoriatic Arthritis (BE ACTIVE 2)

Psoriatic Arthritis

United States, Czechia, Germany, Hungary, Poland, Russian Federation
UCB Pharma

Completed

A Study Evaluating the Efficacy and Impact on Health-related Quality of Life of Levocetirizine in Adults With Seasonal Allergic Rhinitis

Seasonal Allergic Rhinitis

United States
ModernaTX, Inc.

Completed

A Study to Evaluate Safety and Effectiveness of mRNA-1273 COVID-19 Vaccine in Healthy Children Between 6 Months of Age and Less Than 12 Years of Age

SARS-CoV-2

United States, Canada
GlaxoSmithKline

Completed

GR270773 In The Treatment Of Suspected Or Confirmed Gram-Negative Severe Sepsis In Adults

Sepsis

United States, Canada, France, Netherlands, Russian Federation, Taiwan, Czechia, Estonia, Spain, Sweden, Thailand, Germany, Belgium, Israel, United Kingdom, Korea, Republic of, Portugal, Finland, Latvia, New Zealand, Malaysia, South... and more
Population Health Research Institute

Completed

A Trial of Routine Aspiration Thrombectomy With Percutaneous Coronary Intervention (PCI) Versus PCI Alone in Patients With ST-Segment Elevation Myocardial Infarction (STEMI) Undergoing Primary PCI (TOTAL)

ST Elevation Myocardial Infarction | Acute Coronary Syndrome | Percutaneous Coronary Intervention

Canada, United States, Korea, Republic of, United Kingdom, Spain, New Zealand, France, Greece, Austria, Netherlands, Germany, Finland, Serbia, Czech Republic, Australia, Hungary, Brazil, Belgium, China, Macedonia, The Former Yugoslav...
Eli Lilly and Company

Completed

Evaluate Protein C Levels in Severe Sepsis Patients on Drotrecogin Alfa (Activated)

Severe Sepsis

United States, Belgium, Spain, France, Finland, Germany, Canada, United Kingdom, Puerto Rico
Novo Nordisk A/S
Duke Clinical Research Institute

Not yet recruiting

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack (ARTEMIS)

Cardiovascular Risk | Acute Myocardial Infarction (AMI)

Canada, China, United States, Germany, Spain, Korea, Republic of, Netherlands, Australia, Italy, Denmark, India, United Kingdom, Argentina, Turkey, Mexico, Malaysia, Czechia, Poland, Brazil, France, Japan, Bulgaria, Greece, Israel
Medtronic Cardiac Rhythm and Heart Failure
Medtronic

Completed

MASTER I - Microvolt T Wave Alternans Testing for Risk Stratification of Post MI Patients

Myocardial Infarction | Ischemic Cardiomyopathy | Arrhythmia, Ventricular

United States
GlaxoSmithKline

Completed

Anemia Studies in Chronic Kidney Disease: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor Daprodustat-Dialysis (ASCEND-D)

Anaemia | Aspergillosis, Allergic Bronchopulmonary

Australia, Korea, Republic of, Spain, United States, Taiwan, Bulgaria, Mexico, Ukraine, Argentina, Belgium, South Africa, Singapore, Austria, Canada, Netherlands, Russian Federation, Sweden, Turkey, United Kingdom, Germany, Romania and more
Medtronic Cardiac Rhythm and Heart Failure
Medtronic

Completed

MASTER II - Microvolt T Wave Alternans Testing for Risk Stratification of Post MI Patients

Myocardial Infarction | Ischemic Cardiomyopathy | Arrhythmia, Ventricular

United States
Centocor, Inc.
Eli Lilly and Company

Completed

A Study of Abciximab and Reteplase When Administered Prior to Catherization After a Myocardial Infarction (Finesse)

Myocardial Infarction

United States, France, United Kingdom, Belgium, Germany, Spain, Poland, Bulgaria, Romania, Israel, Sweden, Canada, Czech Republic, Argentina, Austria, Denmark, Netherlands, South Africa, Switzerland
Angel Medical Systems
Symbios Clinical

Completed

AngelMed for Early Recognition and Treatment of STEMI (ALERTS)

Acute Coronary Syndrome | Coronary Occlusion | Acute Myocardial Infarction (AMI)

United States
Incyte Corporation

Active, not recruiting

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors

Cervical Cancer | Nasopharyngeal Carcinoma | Advanced Solid Tumors | Mesothelioma | Small-cell Lung Cancer | Esophageal Squamous Cell Carcinoma | Merkel Cell Carcinoma | Sarcomatoid Renal Cell Carcinoma | Anal Carcinoma | Cutaneous Squamous Cell Carcinoma | MSI-H/dMMR Tumors | PD-L1 Amplified Tumor (9p24.1) | Urothelial... and other conditions

Finland, United States, United Kingdom, Belgium, Sweden, Denmark, Norway
Pfizer

Recruiting

PF-06821497 Treatment Of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma

Small Cell Lung Cancer (SCLC) | Follicular Lymphoma (FL) | Castration Resistant Prostate Cancer (CRPC)

United States, Spain, Korea, Republic of, Poland, China, Bulgaria, Russian Federation, Japan
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0313 Cyclophosphamide, Doxorubicin, Vincristine, Prednisone, and Radiation Therapy Followed By Rituximab and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Stage I or Stage II Non-Hodgkin's Lymphoma

Lymphoma

United States
AstraZeneca

Completed

Efficacy, Safety, and Tolerability of Aclidinium Bromide in the Treatment of Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-38) (LAS-MD-38)

Chronic Obstructive Pulmonary Disease

United States, Canada
GlaxoSmithKline

Completed

Perennial Allergic Rhinitis Study In Pediatric Subjects

Rhinitis, Allergic, Perennial

United States, Argentina, Slovakia, Finland, Chile, Mexico, Italy
RTI International
National Institute on Drug Abuse (NIDA)

Completed

Substance Abuse Treatment to HIV Care (SAT2HIV): The Implementation & Sustainment Facilitation Experiment

Substance Use

United States
RTI International
National Institute on Drug Abuse (NIDA)

Completed

Substance Abuse Treatment to HIV Care (SAT2HIV): The Motivational Interviewing-based Brief Intervention Experiment

Substance Use

United States
miRagen Therapeutics, Inc.

Terminated

SOLAR: Efficacy and Safety of Cobomarsen (MRG-106) vs. Active Comparator in Subjects With Mycosis Fungoides (SOLAR)

Cutaneous T-Cell Lymphoma/Mycosis Fungoides

United States, France, Spain, Canada, United Kingdom, Australia, Italy, Belgium
National Cancer Institute (NCI)

Suspended

Testing Pembrolizumab Versus Observation in Patients With Merkel Cell Carcinoma After Surgery, STAMP Trial

Pathologic Stage I Cutaneous Merkel Cell Carcinoma AJCC v8 | Pathologic Stage II Cutaneous Merkel Cell Carcinoma AJCC v8 | Pathologic Stage III Cutaneous Merkel Cell Carcinoma AJCC v8

United States
Rutgers, The State University of New Jersey
University of Alabama at Birmingham; National Institute of Neurological Disorders...

Completed

Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST)

Myocardial Infarction | Stroke | Atherosclerosis | Carotid Stenosis | Cerebral Infarction

United States, Canada
Idorsia Pharmaceuticals Ltd.

Enrolling by invitation

Selatogrel Outcome Study in Suspected Acute Myocardial Infarction (SOS-AMI)

Acute Myocardial Infarction

United States, Spain, Denmark, Canada, Norway, France, China, United Kingdom, Hungary, Switzerland, Germany, Netherlands, Israel, Finland, Belgium, Czechia, Lithuania, Serbia, Austria, Greece, Italy, Bulgaria, Estonia, Poland, Romania, Sl...
Novartis Pharmaceuticals

Completed

Phase II Open Label Trial to Determine Safety & Efficacy of Tisagenlecleucel in Pediatric Non-Hodgkin Lymphoma Patients (BIANCA)

Non-Hodgkin Lymphoma

Japan, Spain, Germany, Australia, Austria, Canada, Italy, Norway, United States, United Kingdom, Finland, France, Denmark, Netherlands
Meda Pharmaceuticals

Completed

A Study to Evaluate the Safety and Tolerability of a Nasal Spray to Treat Perennial Allergic Rhinitis

Perennial Allergic Rhinitis

United States
Sunovion

Completed

Safety and Efficacy of Arformoterol Tartrate Inhalation Solution in Subjects With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease | Emphysema | Bronchitis

United States
Zimmer Biomet

Recruiting

Clinical Outcomes Study of the Nexel Total Elbow

Post-traumatic Arthritis | Degenerative Arthritis | Elbow Joint Destruction | Post-traumatic Lesions | Ankylosed Joints | Advanced Rheumatoid Arthritis | Joint Instability or Loss of Motion | Acute Comminuted Articular Fracture of Elbow Joint Surfaces | Bone Loss Contributing to Elbow Instability | Bilateral...

United States, Australia, Finland, France, Germany, Italy, Netherlands, United Kingdom
UCB Biopharma S.P.R.L.

Completed

A Study to Evaluate the Dose Response Based on the Efficacy, Safety and Tolerability of Bimekizumab in Subjects With Active Psoriatic Arthritis Which is a Type of Inflammatory Arthritis (BE ACTIVE)

Psoriatic Arthritis

United States, Czechia, Germany, Hungary, Poland, Russian Federation
NCIC Clinical Trials Group

Completed

Chemotherapy Before Autologous Stem Cell Transplantation +/- Rituximab in Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma

Lymphoma

United States, Canada, Australia
Roswell Park Cancer Institute

Completed

Chemotherapy, Radiation Therapy, and Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Neuroblastoma | Graft Versus Host Disease

United States
Novartis Pharmaceuticals

Completed

Efficacy at 24 Weeks With Long Term Safety, Tolerability and Efficacy up to 5 Years of Secukinumab in Patients of Active Psoriatic Arthritis (FUTURE 2)

Psoriatic Arthritis

Germany, United Kingdom, Belgium, United States, Australia, Thailand, Russian Federation, Czechia, Canada, Poland, Puerto Rico
GlaxoSmithKline

Completed

Seasonal Allergic Rhinitis In Pediatric Subjects

Rhinitis, Allergic, Perennial

United States
Eli Lilly and Company

Completed

The Study of Drotrecogin Alfa (Activated) in Adult Patients With Severe Sepsis at a Low Risk of Death

Sepsis

Canada, Finland, Belgium, Argentina, Chile, Australia, Austria, Brazil, Czech Republic, Denmark, Egypt, France
Chiesi Farmaceutici S.p.A.

Recruiting

A 52-week, Placebo-controlled Study to Evaluate the Efficacy and Safety of 2 Doses of CHF6001 DPI (Tanimilast), as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis (PILASTER) (PILASTER)

Chronic Obstructive Pulmonary Disease

Bulgaria, United States, Albania, Argentina, Australia, Austria, Bosnia and Herzegovina, Chile, China, Czechia, Georgia, Germany, Greece, Hungary, Israel, Italy, Mexico, Netherlands, New Zealand, North Macedonia, Poland, Romania, Russian... and more
NeuroRx, Inc.

Recruiting

Inhaled ZYESAMI™ (Aviptadil Acetate) for the Treatment of Severe COVID-19 (AVICOVID-2)

SARS-CoV 2 | COVID | ARDS | Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) | Dyspnea | ALI

United States
Exelixis

Recruiting

Study of XL092 in Combination With Immuno-Oncology Agents in Subjects With Solid Tumors (STELLAR-002)

Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | Solid Tumor | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Metastatic Castration-resistant Prostate Cancer

United States, Poland, Spain, Switzerland, Austria, Australia, Belgium, Israel, Italy, New Zealand, France, Germany, United Kingdom
Janssen Research & Development, LLC

Terminated

Study to Evaluate the Antiviral Activity, Clinical Outcomes, Safety, Tolerability, and Pharmacokinetics of Orally Administered Lumicitabine Regimens in Adult Participants Hospitalized With Respiratory Syncytial Virus

Respiratory Syncytial Viruses

Australia, France, United Kingdom, Belgium, Taiwan, United States, Spain, Argentina, Mexico, Bulgaria, Malaysia, Japan, Sweden, Korea, Republic of, Canada, Netherlands, Brazil, Germany, Poland
Abbott Molecular

Completed

Alinity m HR HPV Specimen Collection Study From Women Undergoing Routine Cervical Cancer Screening

Human Papillomavirus

United States
Bausch Health Americas, Inc.

Completed

Safety and Effectiveness of 3 Doses of Crofelemer Compared to Placebo in the Treatment of HIV Associated Diarrhea (ADVENT)

HIV Associated Diarrhea

United States, Puerto Rico

Clinical Trials on Antibiotic Resistant Infection in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Djibouti

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations