Clinical Trials on Antibiotic Disruption

Total 1936 results

St George's, University of London
University College, London

Recruiting

Medical Device (MD) Derived Pharmacokinetic (PK) Parameters for Vancomycin (MD-PK) (MD-PK)

Sepsis | Critical Illness | Septic Shock | Bacteremia | Infection, Bacterial | Antibiotic Side Effect | Antibiotic Resistant Infection | Adult Children

United Kingdom
Mansoura University

Unknown

Conventional Antibiotic Prophylaxis Versus Add-On 5 Days Levofloxacin Before Percutaneous Nephrolithotomy

Sepsis | Infection | Antibiotics | Percutaneous Nephrolithotomy

Egypt
Eurofarma Laboratorios S.A.

Withdrawn

Non-Inferiority Trial Comparing Eurofarma's Experimental Product Saccharomyces Boulardii Versus Floratil® in the Prevention of Antibiotic-Associated Diarrhea (ACROSS)

Antibiotics

Brazil
Otto Helve
University of Helsinki

Not yet recruiting

Autoflor -Lyophilized Capsulated Autological FMT to Restore Gut Microbiome After Treatment With Antibiotics (FMT)

Microbial Colonization | Antibiotic Side Effect

Finland
The Archer-Daniels-Midland Company
Analyze & Realize

Recruiting

The Efficacy of a Probiotic for Antibiotic Associated Gastrointestinal Symptoms (PANDA)

Antibiotic-associated Diarrhea

Germany
Jiangsu Hengrui Pharmaceutical Co., Ltd.

Unknown

The Efficacy and Safety of Daptomycin in the Treatment of Gram-positive Bacterial Infection.

Antibiotic

China
Central Hospital, Nancy, France

Completed

Target Attainment of TDM-guided Infusion of Piperacillin/Tazobactam and Cefepim in Critically Ill Patients (DOSATB)

Sepsis | Critical Illness | Septic Shock | Antibiotic Toxicity

France
Medical University of Lublin

Unknown

Pharmacokinetics of High-dose Tigecycline in Critically Ill Patients

Critical Illness | Septic Shock | Antibiotic Resistant Infection

Poland
Rambam Health Care Campus
Tel-Aviv Sourasky Medical Center

Completed

Fecal Microbiota Transplantation for Eradication of CRE

Microbial Colonization | Antibiotic Resistant Strain

Israel
Rambam Health Care Campus

Withdrawn

Fecal Microbiota Transplantation for Eradication of Carbapenem-resistant Enterobacteriaceae Colonization

Microbial Colonization | Antibiotic Resistant Strain

Israel
Oregon Health and Science University
Oregon Clinical and Translational Research Institute

Completed

Hormonal Contraception and Vaginal Health

Contraceptive Usage | Vaginal Epithelial Disruption

United States
Andrasko, Gary, OD, LLC
Alcon Research

Unknown

Evaluation of Corneal Staining With Various Contact Lens/Solution Combinations

Corneal Staining | Corneal Epithelial Disruption

United States
Universiti Sains Malaysia

Not yet recruiting

Usage of Procalcitonin to Reduce Antibiotics Duration in VAP in Neurosurgical ICU

Antibiotic Side Effect
Central Hospital, Nancy, France

Completed

Discontinuation of Antibiotic Susceptibility Testing on Enterococcus Faecalis Positive Urine Cultures in Hospitalized Patients: an Impact on Antibiotic Prescriptions? (FaecaCible) (FaecaCible)

Antibiotic Susceptibility Reporting

France
Università Vita-Salute San Raffaele

Completed

Bolus Versus Continuous Infusion of Meropenem (MERCY)

Critical Illness | Antibiotic Resistant Infection

Croatia, Italy, Kazakhstan, Russian Federation
Karolinska University Hospital

Completed

Meropenem and Piperacillin Plasma Concentrations During CRRT (ABC2)

Sepsis | Hemolysis | Renal Replacement Therapy | Infection | Antibiotic

Sweden
Bernhard Nocht Institute for Tropical Medicine
German Federal Ministry of Education and Research

Terminated

Probiotic Saccharomyces Boulardii for the Prevention of Antibiotic-associated Diarrhoea (SacBo)

Diarrhea | Antibiotic-associated Diarrhea | Clostridium Difficile

Germany
University Hospital of Cologne
Universitätsklinikum Hamburg-Eppendorf; University of Freiburg; University Hospital...

Unknown

Assessing the Impact of Antimicrobial Exposure and Infection Control Measures on the Spread of VRE (AEGON)

Antibiotic Resistant Infection | VRE Infection

Germany
University of Dundee
University of Southampton; Newcastle University; University of Aberdeen; Chief... and other collaborators

Completed

Developing and Evaluating Interventions to Reduce Inappropriate Prescribing of Antibiotics in Primary Care (WIME)

Antibiotic Prescribing by GPs for URTI

United Kingdom
Perouse Medical
Eclevar Medtech

Completed

A Retrospective, Observational, Monocenter, Study to Describe the Utilization and Overall Safety and Performance of POLYSITE®/SEESITE® Implantable Ports

Chemotherapy | Antibiotics | Parenteral Nutrition | Venous Access | Venous System | Antiviral | Transfusion Blood

France
Shanghai 10th People's Hospital

Completed

Clinical Study of Fecal Microbiota Transplantation in the Treatment of Antibiotic-associated Diarrhea

Antibiotic-associated Diarrhea | Fecal Microbiota Transplantation

China
Duke University

Completed

The DETOURS Trial: De-escalating Empiric Treatment: Opting Out of Rx for Selected Patients With Suspected Sepsis - Opt-Out Protocol Trial

Antibiotic Stewardship

United States
Cubist Pharmaceuticals LLC

Completed

PK and Safety Evaluation of Daptomycin in Children Ages 2-6 With Proven or Suspected Gram-positive Infections

Gram Positive Infection | Concurrent Antibiotic Treatment

United States
Perouse Medical
Eclevar Medtech

Recruiting

A Retrospective, Observational, Multicenter Study to Evaluate the Safety and Performance of POLYSITE® and SEESITE® Implantable Ports

Chemotherapy | Blood Transfusion | Antibiotics | Parenteral Nutrition | Antiviral Drugs | Veinous | Blood Derivatives Transfusion | PMCF Study

France
University of Geneva, Switzerland
University of Lausanne

Recruiting

Antibiotics as Adjuncts to Periodontal Therapy:Pharmacokinetic Considerations and Dosing Strategies (AMA)

Periodontal Diseases | Pharmacokinetics | Antibiotics

Switzerland
Fanzhen Hong

Completed

no Antibiotics for Elective Cesarean With Low Risk of Infection

Antibiotics , Elective Cesarean, China

China
South Shore Hospital

Withdrawn

Probiotics in Hospitalized Patients Study

Antibiotic Associated Diarrhea | Clostridium Difficile Associated Diarrhea
University of Saskatchewan
Jarrow Formulas Inc; Institut Rosell

Completed

Probiotics for Prevention of Antibiotic-associated Diarrhea

Antibiotic-Associated Diarrhea

Canada
Hospital de Granollers

Completed

7-VINCut Antibiotic Stewardship Intervention to Decrease Duration of Antibiotic Treatment and Carbapenem Use in Surgery (7_VINCUT)

Medication Adherence | Medication Errors and Other Product Use Errors and Issues | Antibiotic Resistance, Microbial

Spain
University Medical Center Groningen

Completed

Timing of Maternal Antibiotic Prophylaxis During a Cesarean Section and the Early Infant Gut Microbiome (CSBabyBiome)

Microbial Colonization | Cesarean Section Complications | Antibiotic Side Effect

Netherlands
Shaimaa Mahmoud Abd El-mouez

Unknown

The Utility of Biofire Filmarray in Evaluation of Entero Pathogens Triggers in Patients With Chronic Diarrhea

Antibiotic Resistant Strain | Polymerase Chain Reaction | Chronic Diarrhoea
Insel Gruppe AG, University Hospital Bern

Completed

Optimized Perioperative Antibiotic Prophylaxis in Radical Cystectomy (PAPRAC)

Surgical Site Infection | Antibiotic-associated Diarrhea | Antibiotic Side Effect | Perioperative/Postoperative Complications | Urologic Cancer | Radical Cystectomy | Antibiotic Resistant Infection

Switzerland
BTL Industries Ltd.

Completed

Effect of the XP1100RF Therapy on Thighs Circumference Reduction

Thighs Circumferential Reduction | Subcutaneous Fat Cell Disruption
University of Geneva, Switzerland
University Hospital, Geneva

Recruiting

The OPTIMAL TDM Study: Determining Optimal Beta-lactam Plasma Concentrations Through Therapeutic Drug Monitoring (OPTIMAL TDM)

Efficacy | Toxicity | Beta-lactam Antibiotics | Therapeutic Drug Monitoring | Ceftazidime | Amoxicillin | Meropenem | Imipenem | Piperacillin | Flucloxacillin | Cefepime

Switzerland
Qilu Hospital of Shandong University

Completed

Procalcitonin-Guided Antibiotic Therapy in Bronchiectasis

Bronchiectasis | Procalcitonin | Antibiotic Therapy
Ludwig-Maximilians - University of Munich

Completed

Interruptions, Teamwork, Stress and Patient Outcomes in the Operating Room

Intraoperative Flow Disruptions

Germany
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

FMT to Eradicate Intestinal Colonization by Carbapenem-resistant Enterobacteriaceae (FMT_CRE)

Enterobacteriaceae Infections | Multi-antibiotic Resistance

Italy
Hospices Civils de Lyon

Completed

Prosthesis Infection and One-step Exchange: Pretreatment by Targeted Antibiotic Therapy in At-risk Patients

Prosthetic Joint Infection | Antibiotic Resistant Infection

France
Incheon St.Mary's Hospital

Withdrawn

Optimal Tailored Treatment for H. Pylori Infection

Helicobacter Pylori Infection | Antibiotic Resistant Infection

Korea, Republic of
University of South Alabama
Amerifit Brands Inc

Completed

Probiotics For The Prevention of Antibiotics Associated Diarrhea in the Pediatric Intensive Care Unit

Critical Illness | Antibiotic-associated Diarrhea
University of California, Los Angeles

Withdrawn

Postoperative Antibiotics Following Primary and Secondary Breast Augmentation

Surgical Site Infection | Antibiotic Side Effect | Antibiotic Resistant Infection | Capsular Contracture Associated With Breast Implant
VA Boston Healthcare System

Enrolling by invitation

De-Implementation of Inappropriate Antimicrobial Use After Cardiac Device Procedures (CIED)

Antibiotics Causing Adverse Effects in Therapeutic Use

United States
Central Hospital, Nancy, France

Completed

Serum Concentration of CEFOxitin Used for Antibiotic Prophylaxis in Obese Patients Undergoing BARiatric Surgery (CEFOBAR)

Bariatric Surgery Candidate | Obese | Antibiotic Prophylaxis

France
D'Or Institute for Research and Education

Enrolling by invitation

Phenotypic Profile and Molecular Mechanism of Resistance in Carbapenemase-producing Enterobacterales and Pseudomonas Aeruginosa Isolates From Brazilian Hospitals: Implications for the Introduction of IMIPENEM-RELEBACTAM

Bacterial Infections | Antibiotic Resistant Infection

Brazil
University of Nebraska

Recruiting

Comparison of Gait in Syndesmosis Injuries Treated With Screw Fixation vs Suture Button

Acute Disruption of Ankle Syndesmosis

United States
University of California, San Francisco

Completed

Topical Antibiotic Prophylaxis for Eyelids

Surgical Wound Infection | Surgical Site Infection | Eyelid Diseases | Skin Cancer Face | Surgical Incision | Antibiotic Side Effect | Antibiotic Allergy | Surgical Wound, Recent | Eyelid; Wound

United States
Probi AB

Completed

Efficacy and Safety of a Probiotic Product in Children With Antibiotic-associated Gastrointestinal Disorders.

Antibiotic-associated Loose/Watery Stools

Poland
Rothman Institute Orthopaedics

Unknown

Prospective Evaluation of Oral Antibiotics for Treatment of Shoulder PJI

Oral Antibiotics | Periprosthetic Infection | Revision Total Shoulder Arthroplasty

United States
Brigham and Women's Hospital
National Institute on Aging (NIA)

Completed

Impact of Chronic Circadian Disruption vs. Chronic Sleep Restriction on Metabolism

Aging | Sleep Restriction | Circadian Disruption

United States
University of Aarhus
Takeda; Aarhus University Hospital

Completed

Treatment With PTH After Sternotomy in Cardiac Surgery Patients (PAATH)

Disruption or Dehiscence of Closure of Sternum or Sternotomy

Denmark

Clinical Trials on Antibiotic Disruption

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Drug Interventions

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CROs in Uruguay

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