Clinical Trials on Antibiotic Pharmacokinetics

Total 1123 results

Karolinska University Hospital

Recruiting

Pharmacokinetics of Piperacillin and Meropenem in ICU Patients

Antibiotic Pharmacokinetics

Sweden
Poitiers University Hospital

Not yet recruiting

Therapeutic Monitoring of Antibiotics in Intensive Care Patients: a Cohort Study PopTDM-ICU

Intensive Care Unit | Pharmacokinetic | Antibiotic Therapy
University of Geneva, Switzerland
University of Lausanne

Recruiting

Antibiotics as Adjuncts to Periodontal Therapy:Pharmacokinetic Considerations and Dosing Strategies (AMA)

Periodontal Diseases | Pharmacokinetics | Antibiotics

Switzerland
Cluj Municipal Clinical Hospital
Iuliu Hatieganu University of Medicine and Pharmacy

Recruiting

Pharmacokinetics and Pharmacodynamics of Linezolid Continuous and Intermittent Administration

Critical Illness | Pharmacokinetics | Efficacy | Side-effect of Antibiotic | Intensive Care Unit ICU

Romania
Cui Yimin

Unknown

Association of Genetic Polymorphisms With Capecitabine-based Chemotherapy Toxicities in Chinese Solid Tumor Patients

Solid Tumor | Pharmacokinetics | Drug-Related Side Effects and Adverse Reactions | Capecitabine | Pharmacogenetics

China
Cui Yimin

Unknown

Association of Genetic Polymorphisms With Docetaxel-based Chemotherapy Toxicities in Chinese Solid Tumor Patients

Pharmacokinetics | Drug-Related Side Effects and Adverse Reactions | Solid Tumors | Pharmacogenetics | Docetaxel

China
Institute for Clinical Evaluative Sciences
Canadian Institutes of Health Research (CIHR); Ontario Agency for Health Protection... and other collaborators

Completed

Feedback to Improve Rational Strategies of Antibiotic Initiation and Duration in Long Term Care (FIRST AID -LTC) - Phase 2 (FIRST AID-LTC)

Antibiotic Initiation | Antibiotic Duration

Canada
Institute for Clinical Evaluative Sciences
Canadian Institutes of Health Research (CIHR); Ontario Agency for Health Protection... and other collaborators

Completed

Feedback to Improve Rational Strategies of Antibiotic Initiation and Duration in Long Term Care (FIRST AID-LTC)

Antibiotic Initiation | Antibiotic Duration

Canada
Universita degli Studi di Genova

Not yet recruiting

The Effect of Different Antibiotic Protocols on Peri-implant Tissue Health

Antibiotic
Seed Health

Completed

Metagenomic and Metabolomic Reconstitution of Gut Microbiota After Broad Spectrum Antibiotic Therapy

Antibiotic-associated Diarrhea | Antibiotic Side Effect | Antibiotic-induced Dysbiosis | Antibiotic-induced Epithelial Barrier Disintegrity

Canada
University Hospital, Bordeaux
University of Bordeaux

Recruiting

Antibiotic Prescription Relevance Indicators: Calculation From Electronic Health Records (ARIPPA)

Surgery | Antibiotic

France
Oxford University Clinical Research Unit, Vietnam
National Institute of Hygiene and Epidemiology, Vietnam

Recruiting

Generating Collective Solutions to Reduce Unnecessary Antibiotic Use in Vietnam

Antibiotic Use

Vietnam
Centre Hospitalier Universitaire de Saint Etienne

Not yet recruiting

Antibiotic Prescribing Behavior Among French Intensivist: Construction and Validation of a Questionnaire

Antibiotic Reaction

France
Nantes University Hospital

Completed

Impact on Antibiotic Prescriptions of a Bundle Intervention Conducted by Medical Representatives in General Practitioner Facilities, Based on Operational Demonstration of an Internet Decision Support Tool: Antibioclic (ACTION)

Antibiotic Resistance

France
Central Hospital, Nancy, France
University of Lorraine

Completed

Impact of a Communication Toolkit on Antibiotic Prescribed by General Practitioners: a Randomised Trial

Antibiotic Prescription

France
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Methotrexate

Healthy Subjects | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Methotrexate | Pharmacokinetics of 7-hydroxymethotrexate

United States
University Hospital, Akershus
Oslo University Hospital; Helse Stavanger HF; Sorlandet Hospital HF; Sykehuset... and other collaborators

Terminated

Fecal ESBL Resurgence During Antibiotic Treatment

Antibiotic Drug Resistance
University Hospital Tuebingen
University Hospital of Cologne

Completed

Amplification and Selection of Antimicrobial Resistance in the Intestine II (ASARI II)

Antibiotic Selection Pressure

Germany
Poitiers University Hospital

Completed

Study of Repeated Cefoxitin Administration in Major Abdominal Surgery Using a Microdialysis Technique (PROPHYLOXITINE)

Antibiotic Prophylaxis Surgery

France
Helperby Therapeutics Ltd
Richmond Pharmacology Limited

Completed

Effect of Minocycline & Amoxicillin on Antibiotic Resistant Bacteria and Indigenous Microbiotas (ANTIRESDEV)

Antibiotic Resistant Bacteria

United Kingdom
Uppsala University
Karolinska University Hospital; Sahlgrenska University Hospital, Sweden; University... and other collaborators

Recruiting

Use of New Antibiotics in Sweden

Multi-antibiotic Resistance

Sweden
Federal Research Institute of Pediatric Hematology...

Not yet recruiting

Fecal Microbiome Transplantation (FMT) in Pediatric Patients Colonized With Antibiotic-resistant Pathogens Before Hematopoietic Stem Cell Transplantation (HSCT) (FMT-HSCT)

Antibiotic Resistant Strain

Russian Federation
University of British Columbia

Recruiting

Fecal Transplant for MDRO Decolonization

Multi-antibiotic Resistance

Canada
University of Fribourg

Recruiting

Antibiotic-induced Disruption of the Microbiota (ABERRANT)

Microbiota | Antibiotic Disruption

Switzerland
H. Tolga Çelik

Completed

The Effect of Probiotic Supplement on Urinary D-lactic Acid Level in Newborns

Antibiotic Side Effect

Turkey
Tel-Aviv Sourasky Medical Center

Unknown

Preventive Antibiotic Serum Levels During Caesarean Section

Blood Antibiotic Levels
Milton S. Hershey Medical Center

Completed

Probiotics in Primary Care

Antibiotic Side Effect

United States
Sheba Medical Center
Maccabi Healthcare Services, Israel

Completed

Israeli Judicious Antibiotic Prescription Study (IJAP)

Antibiotic Use | Carriage of Antibiotic Resistant Pathogens
Astellas Pharma Inc

Completed

A Study to Assess the Effect of ASP1941 and Mitiglinide on Their Plasma Concentration

Healthy | Pharmacokinetics of ASP1941 | Pharmacokinetics of Mitiglinide

Japan
University of Novi Sad

Active, not recruiting

Complications After Lower Third Molar Surgery

Postoperative Complications | Infection, Bacterial | Antibiotic Side Effect | Antibiotic Resistant Infection | Antibiotic Resistant Strain | Antibiotic Reaction | Infection, Laboratory

Serbia
Danisco
KGK Science Inc.

Completed

Probiotic Product in Healthy Adults Undergoing Antibiotic Treatment

Antibiotic Therapy

Canada
Makerere University
Mbarara University of Science and Technology; Swedish International Development...

Not yet recruiting

Using the ATC/DDD to Monitor Antibiotic Use at Lower Primary Care Facilities in Southwestern Uganda

ATC/DDD | Antibiotic Utilization

Uganda
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Isavuconazole and Methadone

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Methadone

United States
Astellas Pharma Inc
Basilea Pharmaceutica

Completed

Drug Interaction Study of Isavuconazole and Midazolam

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Midazolam

United States
University of Iowa
National Institutes of Health (NIH); National Center for Advancing Translational...

Completed

Mobile-health Approach to Gather Clinical Information From Patients Following Hospital Discharge

Outpatient Parenteral Antibiotic Therapy

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Isavuconazole and Digoxin

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Digoxin

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Multiple Doses of Isavuconazole and a Single Dose of Bupropion

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Bupropion

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of Sirolimus in Healthy Subjects

Healthy Subjects | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Sirolimus

United States
Pharmbio Korea Co., Ltd.

Completed

Effect of Probiotic Lactobacilli (Lacidofil Cap®) for the Prevention of Antibiotic-Associated Diarrhea

Pulmonary Infection | Antibiotics Associated Colitis

Korea, Republic of
Cairo University

Not yet recruiting

Antibiotic Use and Resistance KAP Among Dental Interns

Antibiotic Side Effect | Antibiotic Resistant Infection
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Multiple Doses of Isavuconazole and Single Dose of Atorvastatin

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Atorvastatin

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Repaglinide and Caffeine

Healthy Subjects | Pharmacokinetics of Caffeine | Pharmacokinetics of Repaglinide

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Metformin

Healthy Subjects | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Metformin

United States
Astellas Pharma Inc
Basilea Pharmaceutica International Ltd

Completed

A Study to Assess the Safety and Pharmacokinetics of Isavuconazole in Healthy Chinese Volunteers

Healthy Volunteers | Pharmacokinetics of BAL4815 | Pharmacokinetics of BAL8728

China
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of Prednisone in Healthy Adult Subjects

Healthy Subjects | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Prednisolone

United States
Astellas Pharma Inc
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Isavuconazole and Tacrolimus

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Tacrolimus

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of the Effect of Ketoconazole at Steady State on the Pharmacokinetics of a Single Dose of Isavuconazole in Healthy Adult Subjects

Healthy Adult Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Ketoconazole

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug Interaction Study of Multiple Doses of Isavuconazole and Single Dose of Dextromethorphan in Healthy Adult Subjects

Healthy Adult Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Dextromethorphan

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Drug-drug Interaction Study Between Lopinavir/Ritonavir and Isavuconazole

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Lopinavir/Ritonavir

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

A Study to Assess the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of a Single Dose of Mycophenolate Mofetil in Healthy Adult Subjects

Healthy Subjects | Pharmacokinetics of Isavuconazole | Pharmacokinetics of Plasma Mycophenolic Acid (MPA) | Pharmacokinetics of Plasma Phenolic Glucuronide of MPA (MPAG)

United States

Clinical Trials on Antibiotic Pharmacokinetics

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