Clinical Trials on Antibiotic-induced Epithelial Barrier Disintegrity

Total 133 results

University of Edinburgh

Recruiting

Fibrosis in Chronic and Delayed Myocardial Infarction (FCDMI)

Aortic Stenosis | Carcinoid Syndrome | Chemotherapy Induced Systolic Dysfunction

United Kingdom
Lexicon Pharmaceuticals

Completed

Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome Not Managed by Stable-Dose Octreotide Therapy

Carcinoid Syndrome

United States
Lexicon Pharmaceuticals

Completed

TELESTAR (Telotristat Etiprate for Somatostatin Analogue Not Adequately Controlled Carcinoid Syndrome)

Carcinoid Syndrome

United States, Australia, Belgium, France, Germany, Italy, Netherlands, Spain, Sweden, United Kingdom, Canada, Israel
Boston Medical Center
Amgen

Withdrawn

Study of Panitumumab in the Treatment of Carcinoid Syndrome

Carcinoid Syndrome

United States
Jiangsu Cancer Institute & Hospital

Completed

Retrospective Study on the Prediction of Radiation-induced Brain Injury in Patients With Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma | Radiation-Induced Temporal Lobe Injury

China
Ipsen

Terminated

Study to Assess the Efficacy and Safety of Different Doses of BIM 23A760 in Patients With Carcinoid Syndrome (CAMPANULA)

Carcinoid Syndrome

Spain, Belgium, Ireland, Czechia, Israel, France, United Kingdom, Latvia, Germany, Russian Federation, Slovakia, Italy, Netherlands, Finland, Austria, Poland, Sweden, Ukraine
Ipsen

Terminated

Comparison of Lanreotide Autogel® and Sandostatin LAR Depot in the Treatment of Clinical Symptoms Associated With Carcinoid Syndrome

Malignant Carcinoid Syndrome

United States
Luo yanrong

Completed

Different Chemotherapy Protocols Combined With Intensity Modulated Radiation Therapy in Patients With Locally Advanced Nasopharyngeal Carcinoma

Drug-Related Side Effects and Adverse Reactions

China
Lexicon Pharmaceuticals

Completed

Study of Telotristat Etiprate (LX1606) in Participants With Symptomatic Carcinoid Syndrome

Carcinoid Syndrome

Germany, United Kingdom
Assistance Publique - Hôpitaux de Paris

Unknown

Smoking Tobacco Cessation Integrated Program of Patients Treated for the Head and the Neck Cancer (INTENT)

Tobacco Use Disorder | Carcinoma, Squamous Cell of Head and Neck

France
Southern China Urology Cancer Consortium

Unknown

Phase II Study of Pazopanib as Second-line Treatment After Sunitinib in mRCC Patients

Carcinoma, Renal Cell | Self Efficacy | Adverse Drug Event

China
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Completed

Effects of Serotonin Excess on Bone in Carcinoid Syndrome

Carcinoid Syndrome

United Kingdom
Sun Yat-sen University
First Affiliated Hospital, Sun Yat-Sen University; Second Affiliated Hospital...

Recruiting

Application of Whole-course Standardized Nutrition Management During Peri-radiotherapy in Patients With Nasopharyngeal Carcinoma After Radiotherapy: a Multicenter Randomized Controlled Clinical Study

Nasopharyngeal Carcinoma | Nutrition Disorders | Radiation Therapy Induced Change

China
Ipsen

Completed

An Efficacy and Safety Study of Somatuline Depot (Lanreotide) Injection to Treat Carcinoid Syndrome (ELECT)

Carcinoid Syndrome

United States, Turkey, Brazil, India, Ukraine, South Africa, Czechia, Latvia, Poland, Russian Federation, Serbia
Lexicon Pharmaceuticals

Completed

Telotristat Etiprate - Expanded Treatment for Patients With Carcinoid Syndrome Symptoms (TELEPATH)

Carcinoid Syndrome

United States, Australia, Belgium, Canada, France, Germany, Israel, Italy, Netherlands, Spain, Sweden, United Kingdom
Lexicon Pharmaceuticals

Completed

Telotristat Etiprate for Carcinoid Syndrome Therapy (TELECAST)

Carcinoid Syndrome

United States, Australia, Belgium, Canada, France, Germany, Israel, Spain, Sweden, United Kingdom, Netherlands
Memorial Sloan Kettering Cancer Center
Bristol-Myers Squibb

Completed

Study of Prophylactic Topical Dapsone 5% Gel Versus Moisturizer for Cetuximab-induced Papulopustular (Acneiform) Rash in Patients With mCRC or HNSCC Without Previous or Concurrent RT

Cetuximab-induced Papulopustular (Acneiform) Rash Who Have | Metastatic Colorectal Cancer or Head and Neck Squamous Cell Carcinoma

United States
Endo Pharmaceuticals

Terminated

Pharmacokinetics, Efficacy and Safety of an Octreotide Implant in Patients With Carcinoid Syndrome

Carcinoid Syndrome

United States
Sanofi

Completed

XENOX - Evaluation of the Efficacy of Xaliproden in Reducing the Neurotoxicity of the Oxaliplatin + 5-FU/LV Chemotherapy

Colorectal Neoplasms | Colorectal Carcinoma | Metastases
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Recruiting

AMT-PET in Monitoring Telotristat Etiprate Treatment in Participants With MetastaticNeuroendocrine Neoplasm

Carcinoid Syndrome | Metastatic Nonfunctional Well Differentiated Neuroendocrine Neoplasm

United States
University Health Network, Toronto
Canadian Institutes of Health Research (CIHR); University of Toronto

Active, not recruiting

Evaluation of Myocardial Changes During BReast Adenocarcinoma Therapy to Detect Cardiotoxicity Earlier With MRI (EMBRACE-MRI)

Breast Neoplasms

Canada
Chandrikha Chandrasekhara
TerSera Therapeutics LLC

Withdrawn

Prospective Assessment of Patients With Neuroendocrine Tumors and Current or Prior History of Carcinoid Syndrome or Diarrhea Undergoing Peptide Receptor Radionuclide Therapy With or Without Telotristat Ethyl (NET-PACS)

Diarrhea | Neuroendocrine Tumors | Carcinoid Syndrome

United States
Cliniques universitaires Saint-Luc- Université...

Terminated

Sandostatin (Octreotide LAR) May Lead to Clinical Improvement Through Receptor Occupation Optimisation (SCIROCCO)

Neuroendocrine Tumors | Carcinoid Syndrome
Ipsen

Completed

A Study to Assess Neuroendocrine Tumour (NET) Patients Currently Treated by Somatuline Autogel for History of Carcinoid Syndrome Associated With Episodes of Diarrhea (SYMNET)

Neuroendocrine Tumors | Carcinoid Syndrome

France, Italy, United Kingdom, Poland, Spain, Hungary, Czechia, Israel
Universiti Kebangsaan Malaysia Medical Centre

Completed

Saliva Substitute Mouthwash in NPC Survivors With Xerostomia: A Randomized Controlled Trial

Xerostomia, Hyposalivation, Saliva Substitute, Radiation-induced Toxicity, Nasopharyngeal Cancer

Malaysia
Chang Gung Memorial Hospital

Completed

Oral Thalidomide and Tegafur-uracil to Decrease Hepatocellular Carcinoma Recurrence

Adult Hepatocellular Carcinoma | Recurrent Hepatocellular Carcinoma | Adverse Reaction to Drug | Vascular Endothelial Growth Factor Overexpression

Taiwan
H. Lee Moffitt Cancer Center and Research Institute
Novartis

Terminated

P:II Above-Label Octreotide-LAR With Insufficiently Controlled Carcinoid Syndrome

Neuroendocrine Carcinoma

United States
ARCAGY/ GINECO GROUP

Completed

Use of FACT-GOG/NTX Questionnaire in Peripheral Neurotoxicity & Validation of a French Version of This Questionnaire

Peritoneal Neoplasms | Ovarian Cancer | Fallopian Tube Cancer

France
Sun Yat-sen University

Recruiting

Compression Therapy as a Prophylactic Method Against CIPN: a Prospective Self-controlled Trial (CIPN)

Nasopharyngeal Carcinoma | CIPN - Chemotherapy-Induced Peripheral Neuropathy

China
Anhui Provincial Hospital

Recruiting

Neoadjuvant Chemoradiotherapy Combined With Camrelizumab and Nimotuzumab for Esophageal Squamous Cell Carcinoma

Toxicity, Drug

China
M.D. Anderson Cancer Center

Withdrawn

Retifanlimab (INCMGA00012) and Telotristat Ethyl for the Treatment of Advanced Neuroendocrine Tumors and Carcinoid Syndrome

Carcinoid Syndrome | Advanced Neuroendocrine Neoplasm
King's College Hospital NHS Trust
Advanced Accelerator Applications

Not yet recruiting

Carcinoid Heart Disease and Peptide Receptor Radiotargetted Therapy (CHARRT)

Carcinoid Tumor | Carcinoid Syndrome | Carcinoid Heart Disease
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

Brain and Central Nervous System Tumors | Neurotoxicity

United States
Affiliated Cancer Hospital & Institute of Guangzhou...

Recruiting

Predictive Study on Acute Radiation Induced Oral Mucositis in Nasopharyngeal Carcinoma Patients

Nasopharyngeal Carcinoma by AJCC V8 Stage | Radiation Induced Mucositis

China
Vanderbilt-Ingram Cancer Center
Entrinsic Bioscience Inc.

Terminated

Enterade in Carcinoid/Non-Carcinoid Syndrome Neuroendocrine Tumor Patients With Quality of Life Limiting Bowel Frequency

Neuroendocrine Tumor | Carcinoid Syndrome

United States
National Cancer Institute (NCI)

Completed

Pharmacokinetics of Ch14.18 in Younger Patients With High-Risk Neuroblastoma

Pain | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma | Stage 4 Neuroblastoma | Neurotoxicity Syndrome

United States
Children's Hospital Los Angeles
National Cancer Institute (NCI)

Completed

N2003-01: Irinotecan, Temozolomide, and Cefixime in Treating Young Patients With Recurrent or Resistant Neuroblastoma

Diarrhea | Neuroblastoma | Drug/Agent Toxicity by Tissue/Organ

United States
Nanfang Hospital, Southern Medical University

Recruiting

Plasma SAA1 Levels in Predicting Response to Radiotherapy-induced Oral Mucositis

Head and Neck Cancer | Nasopharyngeal Carcinoma | Biomarker | Radiotherapy-induced Oral Mucositis

China
Nanfang Hospital, Southern Medical University

Recruiting

Doxepin Solution for Alleviation of Stubborn Breakthrough Pain Induced by Swallowing in Patients Receiving Radiotherapy for Nasopharyngeal Carcinoma

Swallowing-induced Pain

China
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Comparison of Chemoradiotherapy and Chemoradiotherapy Combined With Consolidation Chemotherapy for ESCC

Chemotherapy Effect | Esophageal Squamous Cell Carcinoma | Side Effect of Drug

China
M.D. Anderson Cancer Center

Recruiting

An Investigational Scan (Dual Energy CT) in Detecting Gastrointestinal Carcinoid Tumors

Carcinoid Tumor | Carcinoid Syndrome | Metastatic Carcinoid Tumor | Digestive System Neuroendocrine Tumor G1

United States
University of California, Irvine
Jarrow Formulas Inc

Not yet recruiting

Effect of NAC on Preventing Chemo-Related Cognitive Impairments in Ovarian Ca Pts Treated W/ PBT

Cognitive Impairment | Ovarian Cancer
Shantou University Medical College

Completed

Triple Antiemetic Regimen for Chemoradiotherapy in Cervical Cancer or Nasopharyngeal Cancer

Cervical Cancer | Nasopharyngeal Cancer | Chemotherapy-induced Nausea and Vomiting | Radiation-Induced Nausea and Vomiting | Antiemetic

China
Fujian Cancer Hospital

Unknown

Appaconitine Patch for Oral Mucositis Pain Caused by Chemoradiotherapy in Patients With Nasopharyngeal Cancer

Radiation Induced Oral Mucositis

China
Jiangxi Provincial Cancer Hospital

Recruiting

Bacterial Decolonization to Prevent Radiation-induced Oral Mucositis

Quality of Life | Nasopharyngeal Carcinoma | Bacterial Colonization | Radiation-induced Oral Mucositis

China
European Organisation for Research and Treatment...
Ipsen

Withdrawn

Lanreotide Combined With Telotristat Ethyl or Placebo for the First-line Treatment in Patients With Advanced Well Differentiated Small Intestinal Neuroendocrine Tumours (siNET) With Highly-functioning Carcinoid Syndrome (TELEFIRST)

Small Intestinal NET | Carcinoid Heart Disease
Sun Yat-sen University

Completed

Preventive Effect of Celecoxib on Sorafenib-related Hand Foot Syndrome, a Single Center, Randomized Controlled Clinical Trail

Hepatocellular Carcinoma
St. Louis University
Merck Sharp & Dohme LLC

Terminated

Fosaprepitant for N/V With High-dose Interleukin-2 for Metastatic Melanoma and Renal Cell Carcinoma (HDIL2/Emend)

Chemotherapy-induced Nausea and Vomiting

United States
University of California, San Francisco

Completed

Combination Chemotherapy in Treating Patients With Metastatic Ovarian Cancer or Non-small Cell Lung Cancer

Ovarian Cancer | Lung Cancer | Neurotoxicity

United States
Capital Medical University

Recruiting

Oncolytic Virus Ad-TD-nsIL12 for Progressive Pediatric Diffuse Intrinsic Pontine Glioma

Diffuse Intrinsic Pontine Glioma | Adverse Drug Event | Oncolytic Virus

China

Clinical Trials on Antibiotic-induced Epithelial Barrier Disintegrity

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