Clinical Trials on Antibody-secreting Cells in Germany

Total 2284 results

Farsad Eskandary
Charite University, Berlin, Germany; University of Alberta; HI-Bio

Completed

Felzartamab in Late Antibody-Mediated Rejection

Antibody-mediated Rejection

Austria, Germany
Medical University of Vienna
Charite University, Berlin, Germany; University of Alberta; CSL Behring

Completed

A Pilot Trial of Clazakizumab in Late ABMR

Antibody-mediated Rejection

Austria, Germany
Hannover Medical School

Completed

Elimination of Cardiac and Inflammatory Biomarkers and Adipokines by Therapeutic Plasma Exchange

Antibody-mediated Rejection | Autoimmune Reaction Mediated by Immune Complex

Germany
Charite University, Berlin, Germany

Active, not recruiting

Donor-derived Cell-free DNA for Early Diagnosis of Antibody-mediated Rejection (cfDNA-DSA)

Kidney Transplant Rejection | Antibody-mediated Rejection | Kidney Transplant Failure

Germany
University Hospital Tuebingen

Completed

Influence of Central Nervous Insulin Sensitivity on Insulin Secretion

Insulin Secretion

Germany
University Hospital Tuebingen

Withdrawn

Effect of Spinal Cord Stimulation (SCS) on Insulin Secretion in Humans

Insulin Secretion | Spinal Cord Stimulation

Germany
CSL Behring

Terminated

Efficacy and Safety of Human Plasma-derived C1-esterase Inhibitor as add-on to Standard of Care for the Treatment of Refractory Antibody Mediated Rejection (AMR) in Adult Renal Transplant Recipients

Antibody-mediated Rejection

United States, Spain, France, Netherlands, United Kingdom, Belgium, Germany
University Hospital Tuebingen

Recruiting

The Influence of Genetic Variations in ELAPOR1 or ELAPOR2 on Insulin Secretion and Glucose Regulation in Humans

Type 2 Diabetes | Impaired Insulin Secretion

Germany
University Hospital Tuebingen

Terminated

Effect of Serum LDL Cholesterol Concentration on Pancreatic Insulin Secretion

Insulin Resistance | Hypercholesterolemia | Insulin Secretion

Germany
Alexion Pharmaceuticals

Terminated

Safety & Efficacy of Eculizumab to Prevent AMR in Living Donor Kidney Transplant Recipients Requiring Desensitization

Antibody Mediated Rejection

United States, Germany, Italy, France, United Kingdom, Spain, Sweden, Australia, Netherlands, Norway
Hoffmann-La Roche
Chugai Pharmaceutical

Recruiting

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Patients With Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (Meteoroid)

Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD)

Canada, United States, Korea, Republic of, Australia, Japan, Italy, Brazil, Germany, France, China, Israel
Shire

Terminated

A Multicenter Study to Evaluate the Efficacy and Safety of Cinryze® for the Treatment of Acute Antibody-mediated Rejection in Participants With Kidney Transplant

Acute Antibody-Mediated Rejection (AMR)

United States, Spain, France, Netherlands, Germany, Canada
CSL Behring
ICON Clinical Research

Terminated

Clazakizumab for the Treatment of Chronic Active Antibody Mediated Rejection in Kidney Transplant Recipients (IMAGINE)

Antibody-mediated Rejection

Korea, Republic of, United States, New Zealand, Spain, Taiwan, Netherlands, Australia, France, Canada, Belgium, Czechia, Hungary, Sweden, Austria, Germany
UCB Biopharma SRL

Recruiting

A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Disease (MOG-AD) (cosMOG)

Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOG-AD)

United States, Australia, Belgium, Czechia, France, Germany, Italy, Japan, Korea, Republic of, Mexico, Spain, Sweden, Switzerland, Turkey, Portugal, United Kingdom, Brazil, Ukraine, Taiwan
Heinrich-Heine University, Duesseldorf
Dr. Wetzchewald

Unknown

National Covid-19 Surveillance Physicians (NAT-COV-SURV)

Antibody COVID-19

Germany
Noselab GmbH

Recruiting

Feasibility of a Method for Analysis of Alzheimer´s Disease Specific Proteins in Nasal Secretion (NL02)

Alzheimer Disease | Nasal Secretion | Brain Nose Interface

Germany
University Hospital Schleswig-Holstein
GlaxoSmithKline

Completed

Safety and Efficacy Study of Mepolizumab in Churg Strauss Syndrome (MEPOCHUSS)

Churg Strauss Syndrome

Germany
University Hospital Tuebingen

Completed

B-pVAC-SARS-CoV-2: Study to Prevent COVID-19 Infection in Adults With Bcell/ Antibody Deficiency (B-pVAC)

Immune Deficiency Disease

Germany
Serge Thal

Completed

Effect of Different SARS-CoV-2 Vaccine Schedules and Vaccination Intervals on Reactogenicity and Humoral Immunogenicity

SARS-CoV2 Infection | Tolerance | Immunisation Reaction | Antibody Hypersensitivity

Germany
University of Jena
University Hospital Erlangen; Labor Prof. Pachmann

Recruiting

Association of Adjuvant Radiotherapy of Non-metastatic Breast Carcinoma With Immunomodulation and Circulating Tumor Cell Phenotype in Relation to Patient Age. (CETC)

Tumor Cell, Circulating

Germany
University Hospital Tuebingen
Charite University, Berlin, Germany; Ludwig-Maximilians - University of Munich and other collaborators

Recruiting

Intermittent Fasting to Improve Insulin Secretion (IFIS)

Diabetes type2 | PreDiabetes | Intermittent Fasting | Insulin Secretion

Germany
Novartis Pharmaceuticals

Completed

Extension Study to Assess the Safety and Efficacy of Pasireotide in Participants With Cushing's Disease

Cushing Disease

United States, Italy, France, Germany, United Kingdom
Heinrich-Heine University, Duesseldorf

Completed

Red Blood Cells as a Reflection of Endothelial Function in Old Age

Endothelial Function | Red Blood Cells | Nitric Oxide Pool in Red Blood Cells and Blood Plasma

Germany
Charite University, Berlin, Germany
Klinikum rechts der Isar, TU München, (TUM), Munich, Germany.

Recruiting

Heat Shock Protein (HSP) 70 to Quantify and Characterize Circulating Tumor Cells (HSP70CTC)

Sarcoma | Prostate Cancer | Pancreatic Cancer Stage IV | Breast Cancer Stage IV | Squamous Cell Carcinoma | Melanoma Stage IV

Germany
Nippon Kayaku Co., Ltd.

Completed

Phase II Study on Gusperimus in Patients With Refractory Wegener's Granulomatosis

Wegener's Granulomatosis

United Kingdom, Germany, Sweden, Czech Republic, Denmark, Netherlands
Otsuka Pharmaceutical Europe Ltd

Completed

An Observational Study on Real-world Use and Outcomes of Patients Treated With Tolvaptan for Hyponatraemia Due to SIADH (SAMPLE)

Hyponatremia | Syndrome of Inappropriate ADH (SIADH) Secretion

Germany, Spain
Universitätsmedizin Mannheim

Unknown

Evaluation of Novel Lung Function Parameters in Patients With Interstitial Lung Disease (ILD)

Idiopathic Pulmonary Fibrosis | Interstitial Lung Disease | Sarcoidosis | Pulmonary Healthy Controls | Non-specific Interstitial Pneumonia | Granulomatosis With Polyangiitis (Wegener's Disease)

Germany
Vifor Fresenius Medical Care Renal Pharma

Recruiting

Avacostar - (PASS) (Avacostar)

ANCA-associated Vasculitis

United Kingdom, Germany
Sanofi

Completed

Efficacy of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion

Hyponatremia | Syndrome of Inappropriate ADH (SIADH) Secretion

France, Germany, Belgium, Hungary
Prof. W. Janni

Completed

DETECT III - A Multicenter, Phase III Study to Compare Standard Therapy +/- Lapatinib in HER2-ve MBC-Patients With HER2+ve CTCs (DETECT III)

HER2-negative Metastatic Breast Cancer | HER2-positive Circulating Tumor Cells

Germany
Universitätsmedizin Mannheim
Klinikum Ludwigshafen; Wuerzburg University Hospital; KKS Netzwerk; Klinikum Minden and other collaborators

Completed

Study on Therapy With Dimethylfumarate (DMF) in Patients With Cutaneous T Cell Lymphoma (CTCL) (DMF-CTCL)

Cutaneous T Cell Lymphoma

Germany
AIO-Studien-gGmbH
Bristol-Myers Squibb; Eli Lilly and Company; Merck Sharp & Dohme LLC; Pfizer; Gilead... and other collaborators

Recruiting

Clinical Research Platform Into Molecular Testing, Treatment and Outcome of (Non-)Small Cell Lung Carcinoma Patients (CRISP)

Small-cell Lung Cancer | Non-small Cell Lung Cancer Metastatic | Non-small Cell Lung Cancer Stage I | Metastatic Non-small Cell Lung Cancer (NSCLC) | Non Small Cell Lung Cancer Stage III | Non-small Cell Lung Cancer Stage II

Germany
Heinrich-Heine University, Duesseldorf

Completed

Analysis of Proteome and Pathophysiological Characteristics of Human Blood Cells

Peripheral Blood Mononuclear Cell | Red Blood Cell | Endothelial NO-synthase

Germany
University Hospital, Essen
OnkoDataMed GmbH

Completed

Vismodegib on Locally Advanced Basal Cell Carcinoma Under Real World Conditions (JONAS)

Basal Cell Carcinoma

Germany
University Hospital Muenster
Hannover Medical School; Deutsche Kinderkrebsstiftung; Gesellschaft fur Padiatrische...

Unknown

Prospective Trial for the Diagnosis and Treatment of Intracranial Germ Cell Tumors (SIOPCNSGCTII)

Intracranial Germ Cell Tumors

Germany
Charite University, Berlin, Germany
Helmholtz-Zentrum Dresden-Rossendorf; Max-Delbrück-Centrum Berlin

Recruiting

Artificial Intelligence in Functional Imaging for Individualized Treatment of Head and Neck Squamous Cell Carcinoma Patients (KIVAL-KHT)

HNSCC

Germany
University Hospital Muenster

Recruiting

Establishment of an ELISA for the Recognition of Procalcitonin Variants in Patients With Hyperprocalcitonemia.

Sepsis | Pre-Eclampsia | Adiposity | Microscopic Polyangiitis | Granulomatosis With Polyangiitis | SIRS | Procalcitonin

Germany
MEDA Pharma GmbH & Co. KG

Completed

A Study to Evaluate Effectiveness of Imiquimod 5% Cream in Superficial Basal Cell Carcinoma

Basal Cell Carcinoma

Germany
University Hospital Heidelberg

Recruiting

Treatment of Patients With Relapsed or Refractory CD19+ Lymphoid Disease With T Cells Expressing a Third-generation CAR

Follicular Lymphoma | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Diffuse Large B Cell Lymphoma | Acute Lymphoblastic Leukemia, Pediatric | Acute Lymphoblastic Leukemia, Adult

Germany
Heidelberg University

Completed

Treatment of Malignant Sinonasal Tumours With Intensity-modulated Radiotherapy (IMRT) and Carbon Ion Boost (C12) (IMRT-HIT-SNT)

Sinonasal Malignancies | Adenocarcinoma and Squamous Cell Carcinoma of the Paranasal Sinuses

Germany
AIO-Studien-gGmbH
Merck Sharp & Dohme LLC

Not yet recruiting

Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome (HEAT)

Squamous Cell Carcinoma of the Larynx | Squamous Cell Carcinoma of the Oral Cavity | Squamous Cell Carcinoma of the Oropharynx | Squamous Cell Carcinoma of the Hypopharynx

Germany
Ruhr University of Bochum

Completed

Microarray Analysis of microRNA Expression Profiles in Cutaneous Squamous Cell Carcinoma

Cutaneous Squamous Cell Carcinoma

Germany
Prof. Dr. Clemens Schmitt
Charite University, Berlin, Germany; Janssen-Cilag Ltd.

Active, not recruiting

Ibrutinib, Bortezomib and Rituximab-CHOP for the Treatment of Elderly Patients With CD20+ DLBCL, IPI ≥ 2 (ImbruVeRCHOP)

Diffuse Large B Cell Lymphoma

Germany
University Hospital, Essen

Completed

Window of Opportunity Study of Preoperative Immunotherapy With Atezolizumab in Local SCCHN (PIONEER)

Squamous Cell Carcinoma of Head and Neck

Germany
University of Cologne

Unknown

Multicentre Phase I Trial of Engineered T Cells for Patients With Relapsed or Refractory Primary Cutaneous CD30+ Large T Cell Lymphoma or Transformed CD30+ Mycosis Fungoides (TECLA)

CD30 Positive Cutaneous T Cell Lymphoma | CD30 Positive Transformed Mycosis Fungoides

Germany
Bristol-Myers Squibb

Active, not recruiting

Observational Study of Nivolumab in Participants in Germany With Squamous Cell Carcinoma of the Head and Neck (SCCHN) Progressing on or After Platinum-Based Therapy

Head and Neck Cancer

Germany
Prof. W. Janni

Active, not recruiting

DETECT IV - A Study in Patients With HER2-negative Metastatic Breast Cancer and Persisting HER2-negative Circulating Tumor Cells (CTCs).

HER2-negative and Hormone-receptor Positive Metastatic Breast Cancer | HER2-negative Circulating Tumor Cells | Postmenopausal Female Patients

Germany
Philogen S.p.A.

Terminated

A Phase I/II Study of the Tumor-targeting Human L19-IL2 Monoclonal Antibody-cytokine Fusion Protein in Combination With Rituximab in Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Diffuse Large B-cell Lymphoma (DLBCL)

Germany
Technische Universität Dresden
German Cancer Research Center

Recruiting

A Phase I Trial to Establish the Safety and Maximum Tolerated Dose of High-affinity Autologous BCMA-targeting Chimeric Antigen Receptor (CAR) T-cells in Patients With Relapsed and Refractory B-cell Malignancies (CARLOTTA01)

Neoplasms | Multiple Myeloma in Relapse | Multiple Myeloma, Refractory | Relapsed Diffuse Large B-cell Lymphoma (DLBCL) | Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Germany
Rigel Pharmaceuticals

Enrolling by invitation

A Phase 3 Open Label Extension Study of Fostamatinib Disodium in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia

Warm Antibody Autoimmune Hemolytic Anemia

Spain, United States, Australia, Norway, Belarus, Germany, Netherlands, Belgium, Austria, Bulgaria, Czechia, France, Georgia, Italy, Russian Federation, Serbia, Ukraine, United Kingdom

Clinical Trials on Antibody-secreting Cells in Germany

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Guatemala

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations