Clinical Trials on Anticholinergic Side Effects in Czechia

Total 819 results

Kevelt AS
Pharmasyntez

Unknown

Virexxa (Sodium Cridanimod) w/Progestin Therapy in Pts w/Progesterone Receptor Neg Recurrent/Persistent Endometrial CA

Recurrent or Persistent Endometrial Carcinoma

United States, Ukraine, Belarus, Czech Republic, Slovakia
GP-Pharm

Completed

Leuprolide Acetate 3.75 mg Depot to Treat Prostate Cancer

Prostate Cancer

United States, Austria, Czech Republic, Germany, Hungary, Italy, Slovakia, Spain, United Kingdom
Sandoz

Completed

Phase III Study Comparing the Efficacy and Safety of EP2006 and Filgrastim (PIONEER)

Breast Cancer | Chemotherapy Associated Neutropenia

Czech Republic, Hungary, Latvia, Russian Federation, Slovakia, Ukraine
Sanofi

Completed

XRP6258 Plus Prednisone Compared to Mitoxantrone Plus Prednisone in Hormone Refractory Metastatic Prostate Cancer (TROPIC)

Neoplasms | Prostatic Neoplasms

United States, Argentina, Belgium, Brazil, Canada, Chile, Czech Republic, Denmark, Finland, France, Germany, Hungary, India, Italy, Korea, Republic of, Mexico, Netherlands, Russian Federation, Singapore, Slovakia, South Africa, Spain and more
AstraZeneca

Completed

IRESSA™ (Gefitinib) With Cisplatin Plus Radiotherapy for the Treatment of Previously Untreated Unresected Late Stage III/IV Non-Metastatic Head and Neck Squamous Cell Carcinoma

Neoplasms, Squamous Cell

United States, Czech Republic, Poland, Germany, Belgium, Taiwan, India, Serbia
Hoffmann-La Roche

Completed

A Study of Atezolizumab (an Engineered Anti-Programmed Death-Ligand 1 [PD-L1] Antibody) as Monotherapy or in Combination With Bevacizumab (Avastin®) Compared to Sunitinib (Sutent®) in Participants With Untreated Advanced Renal Cell Carcinoma (IMmotion150)

Renal Cell Carcinoma

United States, Spain, Czechia, United Kingdom, Romania, France, Italy, Germany, Poland
Advanced Medical Diagnostics s.a.

Terminated

Prostate Guided Biopsy Study Evaluating the Diagnostic Performance of Prostate HistoScanning (PHSTT-01)

Prostate Cancer

Austria, Belgium, Bulgaria, Czech Republic, Denmark, Estonia, France, Germany, Hungary, Italy, Latvia, Lithuania, Netherlands, Russian Federation, Spain, Switzerland, Turkey, United Kingdom
Hoffmann-La Roche

Active, not recruiting

A Study of Atezolizumab Plus Tiragolumab and Atezolizumab Plus Placebo as First-Line Treatment in Participants With Recurrent/Metastatic PD-L1 Positive Squamous Cell Carcinoma of the Head and Neck (SKYSCRAPER-09)

Squamous Cell Carcinoma of Head and Neck

United States, Korea, Republic of, United Kingdom, Czechia, New Zealand, France, Spain, Greece, Thailand, Taiwan, Hungary, Italy, Poland
Eisai Inc.
Quintiles, Inc.

Completed

A Study Comparing the Combination of the Best Supportive Care Plus E7080 Versus Best Supportive Care Alone, in Patients With Advanced Lung Cancer or Lung Cancer That Has Spread, Who Have Been Previously Treated, Unsuccessfully, With at Least 2 Different Treatments

Non-Small Cell Lung Cancer

Belgium, Korea, Republic of, Italy, United States, Hungary, United Kingdom, Czechia
Genentech, Inc.

Completed

Study of Ipatasertib or Apitolisib With Abiraterone Acetate Versus Abiraterone Acetate in Participants With Castration-Resistant Prostate Cancer Previously Treated With Docetaxel Chemotherapy

Prostate Cancer

United States, Spain, Czechia, France, Greece, Netherlands, United Kingdom, Romania, Italy
Vaxon Biotech

Completed

Efficacy Study of Vx001 Vaccine in NSCLC Patients

Non-small Cell Lung Cancer Metastatic

Germany, Greece, Spain, Romania, France, Italy, Czechia, Poland
Hoffmann-La Roche

Terminated

A Study of Cobimetinib Plus Paclitaxel, Cobimetinib Plus Atezolizumab Plus Paclitaxel, or Cobimetinib Plus Atezolizumab Plus Nab-Paclitaxel as Initial Treatment for Participants With Triple-Negative Breast Cancer That Has Spread

Breast Cancer

Israel, Italy, Spain, United States, Belgium, Czechia, Australia, United Kingdom, Korea, Republic of, Romania, France, Taiwan, Latvia
Pfizer's Upjohn has merged with Mylan to form Viatris...

Terminated

A Study To Evaluate Pregabalin In The Treatment Of Moderate To Severe Chronic Bone Pain Related To Metastatic Cancer (COPE)

Cancer | Bone Neoplasms | Pain, Intractable

Italy, Spain, United States, Canada, France, Hungary, Poland, Sweden, Taiwan, Korea, Republic of, Philippines, Peru, Venezuela, Finland, Czechia, Egypt, Mexico, Russian Federation, Thailand
Bayer

Terminated

Study of Radium-223 Dichloride Versus Placebo and Hormonal Treatment as Background Therapy in Subjects With Bone Predominant HER2 (Human Epidermal Growth Factor Receptor 2) Negative Hormone Receptor Positive Metastatic Breast Cancer

Breast Neoplasms

Spain, Canada, United States, Finland, Austria, Singapore, Czechia, Israel, Korea, Republic of, Netherlands, Taiwan, United Kingdom, Poland, Germany, Hong Kong, Denmark, Switzerland, Ireland, France, Norway
CureVac

Terminated

Trial of RNActive®-Derived Prostate Cancer Vaccine in Metastatic Castrate-refractory Prostate Cancer

Prostate Cancer

France, Czech Republic, Germany, Poland, Spain, Sweden, Switzerland, United Kingdom
EMD Serono

Terminated

STRIDE - STimulating Immune Response In aDvanced brEast Cancer (STRIDE)

Breast Cancer

Czech Republic, Korea, Republic of, Russian Federation, South Africa, Germany, Slovakia, Austria, United States, Belgium, Poland, Israel, Australia
Bristol-Myers Squibb
Novartis

Active, not recruiting

An Investigational Immuno-therapy Study Of Nivolumab In Combination With Trametinib With Or Without Ipilimumab In Participants With Previously Treated Cancer of the Colon or Rectum That Has Spread (CheckMate 9N9)

Colorectal Cancer | Colorectal Neoplasm | Colorectal Tumors | Colorectal Carcinoma

Italy, United States, Canada, Spain, Argentina, Australia, Belgium, Chile, Czechia, Germany
Hoffmann-La Roche

Completed

A Study to Compare Subcutaneous (SC) Versus Intravenous (IV) Administration of Herceptin (Trastuzumab) in Women With Human Epidermal Growth Factor Receptor (HER) 2-Positive Early Breast Cancer

Breast Cancer

Canada, Germany, Korea, Republic of, Panama, Spain, Turkey, Brazil, Colombia, France, Hungary, Russian Federation, Taiwan, Thailand, Czechia, Italy, Estonia, Peru, South Africa, Sweden, Poland, Israel, Hong Kong, Mexico, Guatemala, Arge... and more
Egetis Therapeutics
Solasia Pharma K.K.

Terminated

Preventive Treatment of OxaLiplatin Induced peripherAl neuRopathy in Adjuvant Colorectal Cancer (POLAR-A)

Colorectal Cancer | Chemotherapy-induced Peripheral Neuropathy

France, Korea, Republic of, Italy, Japan, Spain, Belgium, Germany, United Kingdom, Czechia, Taiwan
AstraZeneca

Active, not recruiting

Comparison of Fulvestrant (FASLODEX™) 250 mg and 500 mg in Postmenopausal Women With Oestrogen Receptor Positive Advanced Breast Cancer Progressing or Relapsing After Previous Endocrine Therapy. (CONFIRM)

Breast Cancer

Belgium, Spain, Italy, United States, Brazil, Czechia, Russian Federation, Chile, Slovakia, Hungary, India, Ukraine, Venezuela, Colombia, Poland, Malta, Mexico
AstraZeneca

Completed

To Assess the Efficacy and Safety of Olaparib Maintenance Monotherapy in the Treatment of Ovarian Cancer (ORZORA)

BRCA or HRR+ Mutated Ovarian Cancer Patients

Italy, Spain, Canada, Czechia, Poland, United Kingdom, Hungary, Bulgaria
Hoffmann-La Roche

Terminated

A Study of Avastin (Bevacizumab) in Combination With Platinum-Based Chemotherapy in Patients With Advanced or Recurrent Squamous Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

France, Poland, Taiwan, Spain, Israel, Belgium, Russian Federation, Czech Republic, Hungary, Australia
Bayer

Completed

Refametinib(BAY86-9766) in RAS Mutant Hepatocellular Carcinoma (HCC)

Carcinoma, Hepatocellular

Belgium, France, Switzerland, Germany, United States, Austria, New Zealand, Hungary, Korea, Republic of, Italy, Hong Kong, Thailand, Spain, Taiwan, Japan, Czechia, United Kingdom
AstraZeneca

Completed

AZD6244 in Combination With Docetaxel Versus Docetaxel Alone in KRAS Mutation Positive NSCLC Patients

Non Small Cell Lung Cancer

United States, Belgium, France, Italy, Spain, Canada, Brazil, Hungary, Peru, Czechia, Bulgaria, Mexico
Sanofi

Completed

Larotaxel Compared To Continuous Administration of 5-FU in Advanced Pancreatic Cancer Patients Previously Treated With A Gemcitabine-Containing Regimen (PAPRIKA)

Pancreatic Neoplasms

United States, Brazil, Poland, Russian Federation, Germany, Turkey, India, Belgium, Czech Republic, Mexico, Chile, Finland, Hungary, Italy, Norway, Canada, Colombia, Peru, Slovakia, Spain, United Kingdom
AstraZeneca

Completed

Randomized Study Of CP-675,206 or Best Supportive Care Immediately After Platinum-Based Therapy For Non-Small Cell Lung Cancer (NSCLC)

Carcinoma, Non-small-cell Lung

United States, Canada, Korea, Republic of, United Kingdom, Czech Republic
UCB Biopharma SRL

Completed

A Study to Investigate the Long-term Safety, Tolerability, and Efficacy of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis

Generalized Myasthenia Gravis

United States, Canada, Czechia, Denmark, France, Germany, Italy, Japan, Poland, Russian Federation, Spain, Taiwan
Pierre Fabre Medicament

Completed

Trial of Vinflunine Plus Capecitabine in Advanced Breast Cancer

Breast Cancer

France, Poland, Ukraine, United Kingdom, Taiwan, Spain, Belgium, Belarus, Mexico, Bulgaria, India, South Africa, Brazil, Russian Federation, Argentina, Hungary, Italy, Serbia, Switzerland, Czechia, Estonia
Pfizer
Merck Sharpe & Dohme LLC

Recruiting

A Study Comparing 3 Study Medicines (Encorafenib, Binimetinib, Pembrolizumab) to 2 Study Medicines (Ipilimumab and Nivolumab) in Patients With Advanced Melanoma (PORTSIDE)

Melanoma

Italy, Spain, Czechia, Germany, Slovakia, Poland, United Kingdom
Bayer

Completed

Standard Dose Versus High Dose and Versus Extended Standard Dose Radium-223 Dichloride in Castration-resistant Prostate Cancer Metastatic to the Bone

Prostatic Neoplasms

United States, Canada, Taiwan, Spain, Australia, Czechia, Germany, Israel, Korea, Republic of, France, Brazil, Chile, Italy, Sweden, United Kingdom
Amgen

Completed

Open Label Extension to SRE Studies in United Kingdom and Czech Republic Only

Bone Metastases in Men With Hormone-Refractory Prostate Cancer | Bone Metastases in Subjects With Advanced Breast Cancer | Bone Metastases in Subjects With Advanced Cancer or Multiple Myeloma

United Kingdom, Czech Republic
Pfizer

Completed

AG-013736 In Combination With Docetaxel Versus Docetaxel Alone For Patients With Metastatic Breast Cancer

Breast Neoplasms

United States, Canada, Czech Republic, Spain, Germany, Italy, India, United Kingdom
AstraZeneca

Recruiting

Study to Assess Neoadjuvant Durvalumab (D) and Platinum-Based Chemotherapy (CT), Followed by Either Surgery and Adjuvant D or CRT and Consolidation D, in Resectable or Borderline Resectable Stage IIB-IIIB NSCLC (MDT-BRIDGE) (MDT-BRIDGE)

Non-small Cell Lung Cancer

Spain, Italy, France, Canada, Portugal, United States, Czechia, Germany, Sweden, Austria, Hungary
Royal Liverpool University Hospital
NCIC Clinical Trials Group; Australasian Gastro-Intestinal Trials Group

Completed

Two Chemotherapy Regimens Compared With Observation in Treating Patients With Completely Resected Pancreatic Cancer

Pancreatic Cancer

France, Australia, Canada, Sweden, Switzerland, Finland, Japan, Germany, United Kingdom, Italy, Czech Republic, Greece, Hungary
Novartis Pharmaceuticals

Completed

Study of Letrozole With or Without BYL719 or Buparlisib, for the Neoadjuvant Treatment of Postmenopausal Women

Breast Cancer

Canada, Italy, Czechia, United States, Belgium, Austria, Germany, Spain, Japan, Lebanon, Australia, Bulgaria, Israel, Netherlands, Colombia, Hong Kong, Brazil
AstraZeneca

Completed

Phase I/II AZD8931/Paclitaxel in Treatment of Advanced Solid Tumours (Phase I) and Advanced Breast Cancer (Phase II) (THYME)

Neoplasms | Breast Cancer | Breast Neoplasms

Brazil, Bulgaria, Czech Republic, Peru, Spain, United Kingdom, Sweden, Hungary, Belgium, Canada, Italy, France, Panama, Switzerland
Sanofi
Regeneron Pharmaceuticals

Terminated

Aflibercept Compared to Placebo in Term of Efficacy in Patients Treated With Gemcitabine for Metastatic Pancreatic Cancer (VANILLA)

Pancreatic Neoplasm

United States, France, Canada, Poland, Romania, Russian Federation, Germany, Italy, Spain, Switzerland, Bulgaria, India, Belgium, Czech Republic, Mexico, Argentina, Hungary, Colombia, Slovakia, Chile, Austria, Greece, Puerto Rico, Cyprus
argenx

Active, not recruiting

Evaluating the Long-Term Safety and Tolerability of Efgartigimod PH20 SC Administered Subcutaneously in Patients With Generalized Myasthenia Gravis (ADAPTSC+)

Generalized Myasthenia Gravis

United States, Belgium, Czechia, Georgia, Germany, Hungary, Italy, Japan, Netherlands, Poland, Russian Federation, Spain
Boehringer Ingelheim

Terminated

LUX-Head&Neck 2: A Phase III Trial of Afatinib (BIBW 2992) Versus Placebo for the Treatment of Head and Neck Squamous Cell Cancer After Treatment With Chemo-radiotherapy

Head and Neck Neoplasms

United States, Argentina, Australia, Austria, Belgium, Brazil, Canada, Chile, Czechia, Denmark, Egypt, Finland, France, Germany, Greece, Hungary, India, Israel, Italy, Japan, Mexico, Netherlands, Portugal, Russian Federation, Spain, Sweden, Switzerlan... and more
Sanofi
Cancer International Research Group (CIRG)

Completed

Combination Chemotherapy With or Without Trastuzumab in Treating Women With Breast Cancer

Breast Neoplasms

United States, France, Brazil, Romania, Russian Federation, Australia, Spain, Sweden, Turkey, India, Slovakia, Taiwan, Belgium, Czech Republic, Tunisia, Uruguay, Argentina, Croatia, Austria, Egypt, Greece, Hungary, Ireland, Israel, Italy, Mexic... and more
Grifols Therapeutics LLC

Completed

Efficacy and Safety of IGIV-C in Corticosteroid Dependent Patients With Generalized Myasthenia Gravis

Myasthenia Gravis

United States, Belgium, Czechia, Estonia, Canada, France, Germany, Hungary, Poland, Lithuania
Bristol-Myers Squibb

Terminated

A Study of Nivolumab and Ipilimumab and Nivolumab Alone in Combination With Trans-arterial ChemoEmbolization (TACE) in Participants With Intermediate Stage Liver Cancer (CheckMate 74W)

Cancer, Hepatocellular

China, United States, Germany, Australia, Italy, Austria, Belgium, Czechia, France, Hong Kong, Japan, Korea, Republic of, Poland, Puerto Rico, Russian Federation, Singapore, Spain, Taiwan, Canada
Dompé Farmaceutici S.p.A
PRA Health Sciences

Completed

A Double-blind Study of Paclitaxel in Combination With Reparixin or Placebo for Metastatic Triple-Negative Breast Cancer (FRIDA)

Metastatic Breast Cancer

United States, Spain, Belgium, Italy, France, Czechia, Poland
Pfizer

Completed

Axitinib (AG-013736) With Or Without Dose Titration (Increase) In Patients With Kidney Cancer

Carcinoma, Renal Cell

United States, Spain, Japan, Germany, Czechia, Russian Federation
AstraZeneca

Completed

Second Line ColoRectal Cancer Therapy in Combination With Combination of FOL- Folinic Acid(Leucovorin), F - Fluorouracil and OX - Oxaliplatin (FOLFOX) (HORIZON I)

Colorectal Cancer

Czech Republic, France, Italy, Spain, United Kingdom, Germany, Canada, Austria, Belgium
Seagen Inc.
Gynecologic Oncology Group; European Network of Gynaecological Oncological... and other collaborators

Completed

A Trial of Tisotumab Vedotin in Cervical Cancer

Cervical Cancer

Belgium, Spain, United States, Denmark, Italy, Germany, Czechia, Sweden
Millennium Pharmaceuticals, Inc.

Completed

Phase 2 Study of Alisertib (MLN8237) in Combination With Paclitaxel Versus Placebo in Combination With Paclitaxel as Second Line Therapy for Small Cell Lung Cancer (SCLC)

Small Cell Lung Cancer

United States, France, Germany, Spain, Belgium, Poland, Canada, Hungary, Italy, Czechia
Sanofi
Cancer International Research Group (CIRG)

Completed

Docetaxel in Breast Cancer

Breast Cancer

France, Hong Kong, Korea, Republic of, Russian Federation, Spain, United States, Argentina, Australia, Belgium, Bosnia and Herzegovina, Brazil, Bulgaria, Canada, China, Colombia, Croatia, Cyprus, Czech Republic, Egypt, Estonia, ... and more
AstraZeneca

Active, not recruiting

Study to Compare the Efficacy and Safety of Olaparib When Given in Combination With Carboplatin and Paclitaxel, Compared With Carboplatin and Paclitaxel in Patients With Advanced Ovarian Cancer

Ovarian Cancer

United States, Czechia, Italy, Belgium, Canada, Germany, Peru, Spain, Japan, Netherlands, United Kingdom, Australia
Genentech, Inc.
Breast International Group; SOLTI Breast Cancer Research Group; Austrian Breast...

Completed

A Study of Neoadjuvant Letrozole + Taselisib Versus Letrozole + Placebo in Post-Menopausal Women With Breast Cancer (LORELEI)

Breast Cancer

United States, United Kingdom, Germany, Australia, Austria, Belgium, Brazil, France, Guatemala, Italy, Korea, Republic of, Panama, Poland, Portugal, Spain, Czechia, Hungary, Mexico, Peru, Switzerland, El Salvador, Chile

Clinical Trials on Anticholinergic Side Effects in Czechia

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