Clinical Trials on Anticholinergic Toxicity

Total 714 results

Battelle Memorial Institute

Completed

Reduced Nicotine Cigarettes in Smokers With and Without Alcohol Use Disorder (RedNic)

Alcohol Drinking | Cigarette Smoking Toxicity

United States
Imperial College London

Completed

Predictive Model of Therapy Outcomes in Breast Cancer Patients

Toxicity From Medication (Endocrine Treatment and Chemotherapy) Given for Breast Cancer Treatment.

United Kingdom
Odense University Hospital

Recruiting

COr Loco-regional Advanced Lung Cancer Treated With Chemo-radiotherapy (COLA) (COLA)

Radiation Toxicity | Cardiac Disease | Cardiac Toxicity | Lung Cancer Stage III | Lung Cancer Stage II

Denmark
101 Therapeutics

Active, not recruiting

Study to Evaluate Pharmacokinetics, Safety & Tolerability of 101-PGC-005 in Healthy, Adult, Human Subjects

Virus Diseases | COVID-19 | Infectious Disease | Glucocorticoids Toxicity

India
University Hospital Tuebingen

Withdrawn

Computer-based Dosage Calculation for Antibiotics

Acute Kidney Insufficiency | Anti-Infective Agent Toxicity

Germany
Campus Bio-Medico University

Unknown

Volume De-escalation in Neoadjuvant Radiochemotherapy of Rectal Cancer

Toxicity

Italy
Herlev and Gentofte Hospital
Odense University Hospital; Zealand University Hospital; Aarhus University Hospital and other collaborators

Recruiting

Monitoring of Arrhythmias in Patients Treated With Antipsychotics (MAPP)

Death, Sudden, Cardiac | Arrythmia | Antipsychotics and Neuroleptics Toxicity

Denmark
Peking University People's Hospital
Jiangsu HengRui Medicine Co., Ltd.

Completed

Apatinib With Ifosfamide Plus Etoposide for Relapsed or Refractory Osteosarcoma (OAIE) (OAIE)

Toxicity | Effect of Drug | Drug

China
University of Arkansas

Terminated

Phase I Clinical Trial of GRID Therapy in Pediatric Osteosarcoma of the Extremity

Radiation Toxicity | Osteosarcoma in Children

United States
Shanghai Zhongshan Hospital

Unknown

Apatinib Plus XELOX as Neoadjuvant Therapy in Locally Advanced Gastric Cancer

Gastric Cancer | Chemotherapy Effect | Chemotherapeutic Toxicity

China
University of California, San Francisco
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Withdrawn

Cigarette Harm Reduction With Electronic Cigarette Use (NIDA-SREC)

Cardiovascular Risk Factor | Nicotine Dependence | Nicotine Dependence, Cigarettes | Nicotine Withdrawal | Tobacco Toxicity

United States
National Cancer Institute, Egypt

Completed

Study of Metronomic Capecitabine and Oxaliplatin Versus XELOX in Egyptian Metastatic Colorectal Cancer Patients

Toxicity | Survival | Clinical Response
Universitaire Ziekenhuizen KU Leuven
Bristol-Myers Squibb

Completed

Apixaban in End-stage Kidney Disease : A Pharmacokinetics Study

ESRD | Anticoagulant Toxicity

Belgium
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Zinc Sulfate in Preventing Loss of Sense of Taste in Patients Undergoing Radiation Therapy for Head and Neck Cancer

Head and Neck Cancer | Radiation Toxicity | Dysgeusia | Oral Complications
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy and Cisplatin With or Without Amifostine for Patients With Stage IIIB or IVA Cervical Cancer

Cervical Cancer | Radiation Toxicity

United States
Xijing Hospital

Recruiting

Preoperative Adjuvant SOX Plus PL-1 Antibody and FLOT Plus PD-1 Antibody for Locally Advanced dMMR Gastric Cancer

Gastric Cancer | Chemotherapeutic Toxicity | Immune-related Adverse Event

China
Laboratorios Sophia S.A de C.V.

Recruiting

Study to Evaluate the Safety and Tolerability of PRO-231 Ophthalmic Solution Versus VIGAMOXI® on the Ocular Surface of Healthy Subjects.

Bacterial Conjunctivitis | Ophthalmological Agent Toxicity

Mexico
Cancer Institute and Hospital, Chinese Academy...

Completed

A Prospective Study of Hypothyroidism After Radiotherapy for Breast Cancer

Breast Neoplasms | Hypothyroidism | Radiation Toxicity

China
Fundacion CRIS de Investigación para Vencer el...
Apices Soluciones S.L.; Amgen

Completed

Skin Toxicity in Patients With Metastatic Colorectal Cancer Treated With Anti-EGFR and Chemotherapy (DERMIA) (DERMIA)

Skin Toxicity

Spain
Peking Union Medical College Hospital

Unknown

the Association Between Blood's and Urinary Heavy Metal Level in Pregnant Women and the Spontaneous Abortion (HMLandSA)

Heavy Metal Toxicity | Spontaneous Abortion

China
Royal Marsden NHS Foundation Trust

Unknown

Parotid-Sparing Intensity-Modulated Radiation Therapy Compared With Conventional Radiation Therapy in Treating Patients With Oropharyngeal or Hypopharyngeal Cancer Who Are at High Risk of Radiation-Induced Xerostomia

Head and Neck Cancer | Xerostomia | Radiation Toxicity

United Kingdom
Massimo Falconi

Recruiting

Financial Toxicity and Patient-Reported Outcomes in GEP-NEN During Treatment (FiReNEN)

Neuroendocrine Tumors

Italy
Ospedale San Carlo Borromeo

Active, not recruiting

Panitumumab Skin Toxicity Prevention Trial (PaSTo)

Colorectal Cancer Metastatic | Skin Toxicity

Italy
National and Kapodistrian University of Athens

Completed

Transthoracic Echocardiography of Inferior Vena Cava Before Spinal Anesthesia Can Predict Hypotension

Intraoperative Complications | Spinal Anesthetic Toxicity | Inferior Vena Cava Abnormality

Greece
Centre Francois Baclesse
Région Normandie

Recruiting

Neurocognitive Impact of Different Irradiation Modalities for Patients With Grade I-II Skull Base Meningioma: (CANCER-COG)

Meningioma | Radiation Toxicity

France
Rabin Medical Center

Completed

IMRT Versus 3DCRT for Locally Advanced Rectal Cancer, Prospective Phase II Study.

Rectal Cancer | Toxicity Due to Radiotherapy | Radiotherapy

Israel
Guangdong Provincial Hospital of Traditional Chinese...

Completed

Safety and Efficacy of Expanded Allogeneic AD-MSCs in Patients With Moderate to Severe Psoriasis (ADMSP)

Psoriasis | Drug Effect | Drug Toxicity | Mesenchymal Stromal Cells

China
Guangdong Provincial Hospital of Traditional Chinese...

Completed

Efficacy and Safety of AD-MSCs Plus Calpocitriol Ointment and PSORI-CM01 Granule in Psoriasis Patients

Psoriasis | Drug Effect | Drug Toxicity | Mesenchymal Stromal Cells

China
Massachusetts General Hospital
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Active, not recruiting

Tau/P-Tau and Neurocognitive Outcomes in Children

Postoperative Cognitive Dysfunction | Child Development | General Anesthetics Toxicity

United States
Institut Cancerologie de l'Ouest

Terminated

Pre-emptive Cycline Treatment on Cetuximab Induced Skin Toxicity in Colorectal Cancer (SKINUX)

Colorectal Cancer Metastatic | Skin Toxicity

France
University of Wisconsin, Madison
National Institute on Deafness and Other Communication Disorders (NIDCD)

Completed

Vitamin A Liver Reserves and Serum Markers of Vitamin A in US Adults at Time of Death

Vitamin A Deficiency | Vitamin A Toxicity

United States
University Hospital, Rouen
Ligue contre le cancer, France

Terminated

Tc-99m Renography and Cisplatin-induced Nephrotoxicity

Cancer | Kidney Failure | Drug Toxicity
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Octreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal Cancer

Colorectal Cancer | Anal Cancer | Drug/Agent Toxicity by Tissue/Organ | Radiation Enteritis

United States
Northwestern University
National Cancer Institute (NCI)

Terminated

Cryotherapy in Preventing Peripheral Neuropathy and Nail Toxicity in Patients With Breast Cancer Who Are Receiving Paclitaxel

Pain | Peripheral Neuropathy | Stage IV Breast Cancer | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIIC Breast Cancer | Recurrent Breast Cancer | Chemotherapeutic Agent Toxicity | Therapy-related Toxicity

United States
Erasmus Medical Center
Gilead Sciences

Unknown

Switching From Tenofovir Disoproxil Fumarate to Abacavir or Tenofovir Alafenamide (BACTAF)

Hiv | Renal Insufficiency,Chronic | Therapeutic Agent Toxicity

Netherlands
University of Nebraska
National Cancer Institute (NCI)

Completed

Cardiac Magnetic Resonance Imaging in Patients With Non-Hodgkin Lymphoma or Hodgkin Lymphoma Receiving Doxorubicin

Lymphoma | Cardiac Toxicity | Chemotherapeutic Agent Toxicity

United States
Sun Yat-sen University
First People's Hospital of Foshan; The First Affiliated Hospital, Guangzhou... and other collaborators

Recruiting

Concurrently vs Sequentially Combined HAIC With Targeted and Immunotherapy in Potentially Resectable HCC (HAIC)

Hepatocellular Carcinoma | Chemotherapy Effect | Chemotherapeutic Toxicity

China
Alexandria University

Recruiting

Assessment of Nerve Damage Biomarkers in Acute and Chronic Organophosphate Toxicity

Nerve Degeneration | Neurotoxicity | Nerve Injury | Genotoxicity | Neuroinflammatory Response | Nerve Damage

Egypt
Ludwig-Maximilians - University of Munich

Recruiting

Lower Urinary Tract Symptoms After Intravesical Therapy (LUTSI)

Overactive Bladder | Lower Urinary Tract Symptoms | Chemotherapy Effect | Chemotherapeutic Toxicity

Germany
University of Aarhus

Active, not recruiting

Cerebral Morbidity After Radiation Therapy for Brain Tumors (WP-12)

Cognitive Impairment | Brain Tumor | Radiation Toxicity

Denmark
Medical University of Graz

Recruiting

Fetal Haemoglobin and Cerebral and Peripheral Oxygenation. (HbFIN)

Preterm Birth | Oxygen Toxicity | Fetal Hemoglobin

Austria
Tata Memorial Hospital
Department of Atomic Energy

Active, not recruiting

To Study the Impact of Radiation Treatment After Surgery in Patient With Locally Advanced Thyroid Cancer. (THYRO-RT)

Radiation Toxicity | Thyroid Cancer Stage IV

India
Jessa Hospital

Withdrawn

A Novel Skin Barrier Protectant for Acute Radiodermatitis (CASP-ORL)

Skin Diseases | Head and Neck Cancer | Radiation Toxicity | Radiodermatitis | Radiation Dermatitis

Belgium
Cancer Trials Ireland

Completed

Spinal Cord Compression Re-Treat Study

Pain | Unspecified Adult Solid Tumor, Protocol Specific | Radiation Toxicity | Spinal Cord Compression

Ireland
First Affiliated Hospital of Chengdu Medical College

Recruiting

Deep-sea Fish Oil for Prevention of Acute Radiation-induced Esophagitis

Esophageal Cancer | Esophagitis | Radiation Toxicity

China
McGill University Health Centre/Research Institute...

Enrolling by invitation

Stereotactic Arrhythmia Radioablation for Ventricular Tachycardia (StAR-VT) (StAR-VT)

Arrhythmia | Ventricular Tachycardia | Radiation Toxicity | Arrhythmic Storm

Canada
Shanghai Zhongshan Hospital
Wu Jieping Medical Foundation

Unknown

A Randomized Open-labeled Study for Comparing Methods of Using Imrecoxib to Treat AS

Ankylosing Spondylitis | Therapeutic Agent Toxicity

China
Lauren Hamel

Recruiting

DISCO: A Patient Intervention to Reduce the Financial Burden of Cancer (DISCO)

Cancer | Breast Cancer | Prostate Cancer | Financial Toxicity | Question Prompt List

United States
Groupe Hospitalier Pitie-Salpetriere

Completed

Monitoring the Hyperammonaemia:TOXicity of Drugs (AmmoTOX) (AmmoTOX)

Metabolic Disease | Adverse Drug Event | Hyperammonemia | Drug Toxicity

France
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery

Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Neurotoxicity | Radiation Toxicity | Cognitive/Functional Effects

United States

Clinical Trials on Anticholinergic Toxicity

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CROs by country

CROs in Congo

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