Clinical Trials on Anticoagulation Reversal

Total 150 results

Brigham and Women's Hospital
CSL Behring

Recruiting

Assessment of Coagulation Factor Levels in Left Ventricular Device (LVAD )Patients Following Temporary Warfarin Reversal With Four Factor Prothrombin Complex Concentrate (4F-PCC) (KVAD)

Anticoagulation | Anticoagulation Reversal

United States
Perosphere Pharmaceuticals Inc, a wholly owned...
Quintiles, Inc.

Completed

Study of PER977 Administered to Subjects With Steady State Edoxaban Dosing and Re-anticoagulation With Edoxaban

Anticoagulation Reversal

United States
Perosphere Pharmaceuticals Inc, a wholly owned...

Completed

Effects of a Double-Blind, Single Dose of PER977 Administered Alone, and Following a Single Dose of Edoxaban (PER977-P1)

Anticoagulant Reversal | Reversal of Edoxaban Induced Anticoagulation

United States
HealthPartners Institute

Completed

Fixed Versus Variable Dosing of 4-factor Prothrombin Complex Concentrate for Emergent Warfarin Reversal (kcentra)

Hemorrhage | Acute Bleeding on Long-Term Anticoagulation Therapy | Significant Bleeding in Patients With a Coagulopathy (Prolonged Thrombin Time) | Urgent Reversal of Vitamin K Antagonist (VKA) Anticoagulation

United States
Charitable Union for the Research and Education...

Active, not recruiting

The Impact of Prednisone on Semen Parameters and Pregnancy Rates Post Vasectomy Reversal

Vasectomy Reversal

United States
Vascular Solutions LLC
Westat; United States Army Medical Materiel Development Activity

Not yet recruiting

Clinical Trial Assessing Non-Inferiority of Freeze Dried Plasma to Fresh Frozen Plasma in Reversing Warfarin

Anticoagulant Reversal

United States
Cohera Medical, Inc.

Completed

Clinical Evaluation of Cohera Sylys Surgical Sealant as an Adjunct to Standard Bowel Anastomosis Closure

Stoma Reversal Procedure
Octapharma

Completed

Study of Octaplex (Human Prothrombin Complex Concentrate) and Fresh Frozen Plasma in Patients Under Vitamin K Therapy Antagonist Needing Urgent Surgery or Invasive Procedures

Reversal of Anticoagulant Treatment

United States
Hanlim Pharm. Co., Ltd.

Recruiting

Evaluation of the Clinical Efficacy and Safety of BriTurn Injection or BrisTurn Prefilled Injection

Reversal of Neuromuscular Blockade

Korea, Republic of
Stony Brook University
Merck Sharp & Dohme LLC

Completed

Quality of Recovery After Reversal With Neostigmine or Sugammadex.

Incomplete Reversal of Neuromuscular Block

United States
Cukurova University

Completed

The Effect of Dexamethasone on Sugammadex Reversal

Incomplete Reversal of Neuromuscular Block

Turkey
William S. Middleton Memorial Veterans Hospital
University of Wisconsin, Madison

Completed

Prospective Evaluation of an Extended Interval of INR Follow-up in a VA Anticoagulation Service

Anticoagulation
University of Medicine and Pharmacy at Ho Chi Minh...

Unknown

Impact of Clinical Pharmacist Interventions in Vitamin K Antagonists Management at One Teaching Hospital in Vietnam

Anticoagulation

Vietnam
University of Alberta

Completed

Evaluation of Maintenance Dosing vs Loading Dosing Upon Restarting Warfarin Therapy: A Prospective Randomized Trial

Anticoagulation

Canada
Bristol-Myers Squibb
Pfizer

Completed

Multi-center Study to Evaluate the Safety of Apixaban (BMS-562247) in Indian Subjects Undergoing Elective Total Knee Replacement or Total Hip Replacement Surgery

Anticoagulation

India
Bristol-Myers Squibb
Badalona Serveis Assistencials; IMS Health

Completed

Cost of Monitoring Patients Treated With Vitamin K Antagonists in Spain

Anticoagulation
University of Turku

Unknown

Excessive Warfarin Anticoagulation - Causes and Consequences (EWA)

Anticoagulation

Finland
Goethe University

Unknown

Influence of Clonidine on Thrombozytes of Blood of Patients Under Anticoagulation Therapy With ASS and Clopidogrel

Anticoagulation

Germany
Bayer
Janssen Research & Development, LLC; RTI Health Solutions

Completed

Patient and Physician Knowledge of Key Safety Messages

Anticoagulation

Germany, United Kingdom, France, Spain
Aalborg University Hospital

Completed

Prospective Trial of a Validated Algorithm for Warfarin Dosing

Anticoagulation
Bristol-Myers Squibb

Completed

A Study to Assess the Effects of 2 Prothrombin Complex Concentrates on the Pharmacodynamics of Apixaban in Healthy Adult Subjects

Anticoagulation
Novocol Pharmaceutical of Canada, Inc.

Completed

Study of OraVerse® for Safety and Efficacy in Pediatric Dental Patients

Anesthesia, Local | Dental Anesthesia | Anesthesia, Reversal

United States
sara nabil

Recruiting

Oraverse Versus Laser (RCT)

Reversal of Local Anesthesia in Children

Egypt
Biosite

Completed

User Performance Evaluation of the INRatio® Prothrombin Time (PT) Monitoring System With a New INRatio Test Strip Designed for Low Sample Volume and Heparin Insensitivity (ECLIPSE-02)

Oral Anticoagulation

United States
GWT-TUD GmbH

Recruiting

Register for New Oral Anticoagulants (NOAC)

Anticoagulation Treatment

Germany
University Medical Centre Ljubljana

Completed

Comparison of Biocompatibility of Plasmapheresis Procedures With Citrate and Heparin Anticoagulation

Anticoagulation | Apheresis

Slovenia
RenJi Hospital

Recruiting

Preliminary Exploration of Thromboelastography in the Monitoring of Anticoagulation in Maintenance Hemodialysis Patients

Hemodialysis | Anticoagulation | Thromboelastography

China
University Hospital Tuebingen
Heart and Diabetes Center North Rhine-Westphalia

Unknown

Specific PoC Testing of Coagulation in Patients Treated With DOAC 1 (SPOCT-DOAC 1)

Anticoagulation With NOAC

Germany
China National Center for Cardiovascular Diseases

Recruiting

Antithrombotic Therapy After Coronary Artery Bypass Grafting Combined With Coronary Endarterectomy

Anticoagulation | Coronary Endarterectomy

China
Mayo Clinic
LivaNova

Completed

Improved Time in Therapeutic Range With Patient Self-Testing of Their INR Compared to Usual Care

Management of Anticoagulation

United States
Yasser Elnahas

Completed

Safety And Efficacy of Low Dose Oral Anticoagulants And Aspirin Therapy

Anticoagulation in Pregnancy

Egypt
Diagnostica Stago

Completed

Apixaban Validation Study - Additional Study on Fresh Samples

Anticoagulation With Apixaban

United States
University Hospital, Montpellier

Completed

Evaluation of the Contribution of a Pre-consultation Questionnaire on the Therapeutic Education (EDUCONSULT)

Under Oral Anticoagulation Patients

France
University Medical Center Groningen
Boehringer Ingelheim; CSL Behring

Unknown

Reversal of Dabigatran With Prothrombin Complex Concentrate

Drug Action Reversal

Netherlands
Kantonsspital Winterthur KSW
University of Zurich; Zurich University of Applied Sciences

Completed

Prehabilitation - Enhanced Recovery After Colorectal Surgery (pERACS)

Colorectal Surgery | Surgical Operation With Reversal of External Stoma

Switzerland
University of South Florida

Completed

Enhanced Pharmacist-Managed Anticoagulation Service in a University-based Family Medicine Clinic

Anticoagulation | Home INR Monitoring
Genentech, Inc.

Active, not recruiting

A Study to Characterize Access to Specialty Care Received by American Indians/Alaska Natives (CATORI)

Specialist Referral: Neurology | Specialist Referral: Ophthalmology | Specialist Referral: Oncology

United States
RenJi Hospital

Unknown

Minimally Invasive Lumbar Aneasthesia Used for Cesarean Section

Spinal Anesthesia | Anticoagulation | Minimally Invasive

China
IRCCS Policlinico S. Donato

Not yet recruiting

Developing Anticoagulation Self-Report Measure in Adults (PERSONAE)

Adults Undergoing Oral Anticoagulation Therapy

Italy
Abbott Medical Devices
Thoratec Europe Ltd

Completed

Study of Reduced Anti-coagulation/Anti-platelet Therapy in Patients With the HeartMate II Left Ventricular Assist System (LVAS) (TRACE) (TRACE)

Anticoagulation | Left Ventricular Assist Device

United States, Austria, France, Germany, Czechia
University Hospital Tuebingen
Heart and Diabetes Center North Rhine-Westphalia

Completed

Point-of-Care Testing of Coagulation in Patients Treated With Direct Oral Anticoagulants 2 (POCT-DOAC 2)

Anticoagulation With Direct Oral Anticoagulants
University Hospital Tuebingen
Heart and Diabetes Center North Rhine-Westphalia

Completed

Point-of-Care Testing of Coagulation in Patients Treated With Direct Oral Anticoagulants 1 (POCT-DOAC 1)

Anticoagulation With Direct Oral Anticoagulants
University of California, Irvine

Completed

Evaluation of Maternal and Fetal Outcomes in Pregnancies in Women With Prosthetic Heart Valves

Pregnancy | Anticoagulation | Prosthetic Heart Valves

United States
Johann Wolfgang Goethe University Hospital

Completed

Choice of Valve Substitute in the Era of Oral Anticoagulation Self-Management

Anticoagulation | Mechanical Heart Valve Replacement
Seoul National University Bundang Hospital

Completed

Comparison of QoR-15 in Laparoscopic Cholecystectomy: Sugammadex vs. Neostigmine

Laparoscopic Cholecystectomy | Quality of Recovery | Neuromuscular Blockade Reversal Agent | Sugammadex | Neostigmine

Korea, Republic of
Universitaire Ziekenhuizen KU Leuven
University of Pittsburgh; Sheba Medical Center; Mount Sinai Hospital, Canada; Leiden... and other collaborators

Unknown

TRAP Intervention STudy: Early Versus Late Intervention for Twin Reversed Arterial Perfusion Sequence (TRAPIST)

Twin Reversal Arterial Perfusion Syndrome

Spain, Germany, Israel, Belgium, Netherlands, Canada, United States, Austria, France, Italy, United Kingdom
Fundació Institut de Recerca de l'Hospital de la...

Completed

Clinical Outcomes From Patient Self-management of Antivitamin K Treatment (ORION)

Self Management of Oral Anticoagulation With VKA Therapy

Spain
Mayo Clinic

Completed

Comparison of Point of Care to Lab INR in Dialysis Patients on Warfarin

Anticoagulation in Dialysis Patients
Merck Sharp & Dohme LLC

Completed

Safety of Sugammadex for the Reversal of Neuromuscular Blockade in American Society of Anesthesiologists (ASA) Class 3 or 4 Participants (MK-8616-145)

Reversal of Neuromuscular Blockade

United States, Austria, Denmark, Germany
Chulalongkorn University

Completed

No Monitoring of Post-filter Ionized Calcium in Regional Citrate Anticoagulation

Continuous Renal Replacement Therapy | Regional Citrate Anticoagulation | Ionized Calcium

Thailand

Clinical Trials on Anticoagulation Reversal

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