Clinical Trials on Antipsychotics and Neuroleptics Toxicity

Total 624 results

Sandoz
Sandoz GmbH

Completed

Phase III Study Comparing the Efficacy and Safety of LA-EP2006 and Neulasta® (PROTECT-1)

Breast Neoplasms | Chemotherapeutic Toxicity | Chemotherapy-induced Neutropenia | Neutropenic Complications

Russian Federation, Brazil, India, Mexico, Romania, Ukraine
University Hospital, Caen
Heidelberg University; Groupe Hospitalier Pitie-Salpetriere; University Hospital... and other collaborators

Recruiting

Atrial Fibrillation in Active Cancer Patients (AFIB-CANCER)

Cancer | Atrial Fibrillation | Drug Toxicity | Cardiovascular Complication

France
Peking University People's Hospital
Peking University; Northwestern University

Unknown

Epigenetic Biomarker for Advanced Osteosarcoma Using Famitinib and Camrelizumab (EBAOFC)

Drug Resistance to Famitinib and Camrelizumab | Biomarkers for Efficacy and Toxicity

China
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Treating Patients With Recurrent PCNSL With Carboplatin/BBBD and Adding Rituxan To The Treatment Regimen

Lymphoma | Thrombocytopenia | Brain and Central Nervous System Tumors | Drug/Agent Toxicity by Tissue/Organ

United States
Rush University Medical Center
National Cancer Institute (NCI)

Unknown

Amifostine and High-Dose Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Chronic Myelogenous Leukemia

Myelodysplastic Syndromes | Leukemia | Neutropenia | Drug/Agent Toxicity by Tissue/Organ

United States
National Science Centre, Poland
Medical University of Warsaw

Recruiting

The New LC-MS/MS Method for Determination of Unbound Tacrolimus in Plasma (FreeTAC)

Kidney Transplant Rejection | Liver Transplant; Complications | Immunosuppression | Metabolism Medication Toxicity | Genetic Predisposition | Kidney Transplant; Complications | Liver Transplant Rejection

Poland
Barretos Cancer Hospital

Unknown

Impact of AferBio® on Quality of Life and Chemotherapy Toxicity in Lung Cancer Patients (AFERBIO)

Quality of Life | Infection | Drug Toxicity

Brazil
European Institute of Oncology

Completed

Prevention of Chemotherapy-induced Cardiotoxicity in High-risk Patients

Cardiotoxicity | Chemotherapeutic Toxicity

Italy
University of Florence

Not yet recruiting

Improving Food Pleasure and Intake of Oncology Patients Receiving Chemotherapy

Breast Cancer | Colon Cancer | Chemotherapeutic Toxicity
Tonix Pharmaceuticals, Inc.
National Institute on Drug Abuse (NIDA); Premier

Not yet recruiting

Comparing Efficacy & Safety Of TNX-1300 To Placebo With UC For Treatment Of Acute Cocaine Intoxication In ED Subjects (CATALYST) (CATALYST)

Cocaine Use | Cocaine Abuse | Cocaine Adverse Reaction | Cocaine Intoxication | Cocaine Toxicity
Sahlgrenska University Hospital, Sweden
Vastra Gotaland Region

Completed

Return to Work Among Cancer Survivors With Treatment-induced Survivorship Syndromes

Gynecologic Cancer | Prostate Cancer | Radiation Injuries | Radiation Toxicity | Radiotherapy Side Effect | Malignancy | Cancer Survivors | Radiation Syndrome

Sweden
Asan Medical Center

Recruiting

Salvage Hypofractionated Accelerated Versus Standard Radiotherapy for Biochemical Failure After Prostatectomy (SHARE)

Quality of Life | Prostate Cancer | Radiation Toxicity | Biochemical Recurrence | Survival | Radiation | Hypofractionation | Dose Escalation

Korea, Republic of
University of California, San Francisco

Recruiting

Pupillary Unrest as an Indicator of Central Opioid Effect in Subjects 40-60 Years of Age

Respiratory Depression | Opioid Toxicity | Pupillary Miosis

United States
Centre Francois Baclesse

Completed

G-CSF in Preventing Neutropenia in Women Receiving Chemotherapy for Breast Cancer

Breast Cancer | Neutropenia | Chemotherapeutic Agent Toxicity

France
University of Aarhus

Recruiting

Cognitive Function After Radiation Therapy for Primary Brain Tumours

Cognitive Impairment | Radiation Toxicity | Primary Brain Tumour

Denmark
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Terminated

Amifostine and Melphalan in Treating Patients With Primary Systemic Amyloidosis Who Are Undergoing Peripheral Stem Cell Transplantation

Multiple Myeloma and Plasma Cell Neoplasm | Drug/Agent Toxicity by Tissue/Organ

United States
Gynecologic Oncology Group
National Cancer Institute (NCI); Canadian Cancer Trials Group

Completed

Radiation Therapy and Cisplatin With or Without Epoetin Alfa in Treating Patients With Cervical Cancer and Anemia

Anemia | Cervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Radiation Toxicity | Cervical Squamous Cell Carcinoma | Drug Toxicity | Stage IIB Cervical Cancer | Stage III Cervical Cancer | Stage IVA Cervical Cancer

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Salivary Gland Surgery Before Radiation Therapy in Preventing Radiation-Caused Xerostomia in Patients With Head and Neck Cancer

Head and Neck Cancer | Xerostomia | Radiation Toxicity

United States, Canada
Washington University School of Medicine
St. Jude Children's Research Hospital

Completed

Translating ECHOS2 Into an mHealth Platform (ECHOS2)

Childhood Cancer | Pediatric Cancer | Cardiac Toxicity

United States
Aalborg University Hospital
University of Aarhus

Unknown

Oxygenation Targets in Cardiac Surgery Patients - a Before-and-after Study

Cardiac Surgery | Cardiopulmonary Bypass | Acute Lung Injury | Hyperoxia | Oxygen Toxicity

Denmark
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors

Brain and Central Nervous System Tumors | Long-term Effects Secondary to Cancer Therapy in Children | Drug/Agent Toxicity by Tissue/Organ | Bone Marrow Suppression

United States
Stanford University
National Cancer Institute (NCI)

Completed

Phone or Email Reminder in Increasing Vaginal Dilator Use in Patients With Gynecologic Cancers Undergoing Brachytherapy

Cervical Cancer | Endometrial Cancer | Radiation Toxicity | Vaginal Cancer

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain Tumor

Brain and Central Nervous System Tumors | Radiation Toxicity

United States
Qianfoshan Hospital

Active, not recruiting

Risk Factors and Machine Learning Model for Diuretics Related Acute Kidney Injury

Acute Kidney Injury | Diuretic Toxicity

China
Peking University Third Hospital

Recruiting

Effects of Anti-VEGF Targeted Drugs on Patients' Blood Pressure and Endothelial Function

Endothelial Dysfunction | Cardiac Toxicity | VEGF

China
Assiut University

Not yet recruiting

Livertoxcicity in Acute Leukemia Patients During Chemotherapy Treatment

Liver Toxicity, Chemically-Induced
Centre Hospitalier Universitaire Saint Pierre
Masimo Corporation; Centre Hospitalier Universitaire Brugmann

Completed

ORI to Reduce Hyperoxia After Out Hospital Cardiac Arrest (ORI-ONE)

Out-Of-Hospital Cardiac Arrest | Oxygen Toxicity

Belgium
Peking University People's Hospital

Completed

Apatinib for Inoperable Advanced Chondrosarcoma (AIAC)

Efficacy | Toxicity, Drug

China
Peking University People's Hospital
Jiangsu HengRui Medicine Co., Ltd.

Completed

Apatinib Plus Anti-PD1 Therapy for Advanced Osteosarcoma (APFAO)

Toxicity | Overall Survival | Progression-free Survival | Clinical Benefit Rate

China
Uppsala University Hospital
Swedish Cancer Society; Lantmännen AB; Sjöbergstiftelsen; Onkologiska klinikens...

Recruiting

Role of Antisecretory Factor in Dihydropyrimidine Treatment of Colorectal Cancer (SALFLADMET)

Dihydropyrimidine Induced Gastrointestinal Toxicity in Colorectal Cancer

Sweden
Aarhus University Hospital
Oslo University Hospital

Completed

Re-irradiation for Pelvic Recurrences in Rectal Cancer Patients (Re-RAD-I)

Recurrence | Rectal Cancer | Radiation Toxicity

Norway, Denmark
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Safety Assessment of Concurrent Radiotherapy and Novel Systemic Therapy for Breast Cancer (RADIOCOM)

Chemotherapeutic Toxicity | Radiotherapy; Complications | PARP Inhibitor | Immune Checkpoint Inhibitor | Trastuzumab | Breast Cancer, Familial Male | CDK4/6 Inhibitor | Pertuzumab

China
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Evaluation of Memory Skills in Patients Receiving Radiation Therapy for Brain Metastases

Metastatic Cancer | Radiation Toxicity | Cognitive/Functional Effects

United States, Canada
University of California, San Francisco

Active, not recruiting

Predicting the Risk of Failure in Patients Undergoing Radiation Therapy for Localized Prostate Cancer

Prostate Cancer | Radiation Toxicity

United States
John Fiveash, MD

Completed

Pilot Trial Evaluating Stereotactic Body Radiotherapy With Integrated Boost for Clinically Localized Prostate Cancer (RAD 1203)

Sexual Dysfunction | Prostate Cancer | Prostate Adenocarcinoma | Radiation Toxicity

United States
Tel-Aviv Sourasky Medical Center

Recruiting

Evaluation and Management of Cardio Toxicity in Oncologic Patients

Heart Failure

Israel
University Hospital, Bordeaux

Completed

Early Detection of Anthracycline Cardiotoxicity by Echocardiographic Analysis of Myocardial Deformation in 2D Strain (CA2D)

Leukemia | Cardiac Toxicity

France
Myocardial Solutions

Completed

MyoStrain CMR for the Detection of Cardiotoxicity (Prefect)

Heart Failure | Cardiotoxicity | Chemotherapeutic Toxicity

Germany
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy in Treating Patients With Stage II or Stage III Oropharyngeal Cancer

Head and Neck Cancer | Radiation Toxicity

United States, Canada
Virginia Commonwealth University
National Cancer Institute (NCI)

Completed

Electrical Stimulation Therapy Using the MC5-A Scrambler in Reducing Peripheral Neuropathy Caused by Chemotherapy

Pain | Unspecified Adult Solid Tumor, Protocol Specific | Neurotoxicity | Peripheral Neuropathy | Chemotherapeutic Agent Toxicity
Groupe Hospitalier Pitie-Salpetriere

Completed

Monitoring the Antiphospholipid Syndrome:TOXicity of Drugs (APSTOX) (APSTOX)

Antiphospholipid Syndrome | Adverse Drug Event | Drug Toxicity | Immune Disease

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Calcium Aluminosilicate Anti-Diarrheal in Treating and Preventing Diarrhea in Patients With Metastatic Colorectal Cancer Receiving Irinotecan

Diarrhea | Colorectal Cancer | Chemotherapeutic Agent Toxicity

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
Celgene Corporation

Completed

The Addition of Nab-paclitaxel (Abraxane) to First Line Treatment of Metastasized Oesophagogastric Carcinoma (ACTION) (ACTION)

Esophageal Cancer | Toxicity

Netherlands
Barrett Cancer Center
National Cancer Institute (NCI)

Unknown

Hyperbaric Oxygen Therapy in Treating Patients With Radiation Necrosis of the Brain

Brain and Central Nervous System Tumors | Radiation Toxicity | Cognitive/Functional Effects

United States
Herlev Hospital
Rigshospitalet, Denmark; University of Copenhagen; Danish Cancer Society

Recruiting

Esophagus-sparing Radiotherapy for Metastatic Spinal Cord Compression. (ESO-SPARE)

Esophagitis | Radiation Toxicity | Patient Reported Outcome Measures | Metastatic Spinal Cord Compression

Denmark
G1 Therapeutics, Inc.

Terminated

Trilaciclib, a CDK 4/6 Inhibitor, in Patients Receiving FOLFOXIRI/Bevacizumab for Metastatic Colorectal Cancer (mCRC): (PRESERVE1)

Colorectal Cancer Metastatic | Chemotherapeutic Toxicity | Myelosuppression-Adult

China, Spain, United States, Hungary, United Kingdom, Poland, Ukraine, Italy
University of Rochester
Medical College of Wisconsin

Recruiting

A Study to Determine the Preferred Dose of the Drug, Lisinopril, for Preventing Urinary Toxicity Following Radiotherapy for Prostate Cancer

Prostate Cancer | Radiation Toxicity | Urinary Complication

United States
Rigshospitalet, Denmark
Odense University Hospital; Zealand University Hospital; Aarhus University Hospital and other collaborators

Recruiting

Danish Elder Lymphoma Patient Hematopoietic Investigation (DELPHI)

Lymphoma | Chemotherapeutic Toxicity | Chemotherapy-induced Neutropenia | Chemotherapy-Related Leukemia

Denmark
hanan fawzy

Active, not recruiting

Acute Toxicity After Moderate Hypo-fractionated Intensity Modulated Radiotherapy IMRT or Prostate Cancer

Radiation Toxicity

Egypt
Bangkok Metropolitan Administration Medical College...

Completed

Curcuminoids and Contrast-induced Acute Kidney Injury

Chronic Kidney Diseases | Acute Kidney Injury | Contrast Media Toxicity | Curcuminoid

Thailand

Clinical Trials on Antipsychotics and Neuroleptics Toxicity

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in South Korea

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations