Clinical Trials on Any Solid Tumor With an EZH2 GOF Mutation
Total 450 results
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Epizyme, Inc.CompletedSynovial Sarcoma | Epithelioid Sarcoma | Renal Medullary Carcinoma | Malignant Rhabdoid Tumors (MRT) | Rhabdoid Tumors of the Kidney (RTK) | Atypical Teratoid Rhabdoid Tumors (ATRT) | Selected Tumors With Rhabdoid Features | INI1-negative Tumors | Malignant Rhabdoid Tumor of Ovary | Poorly Differentiated... and other conditionsFrance, United States, Australia, Taiwan, Belgium, United Kingdom, Canada, Germany, Italy
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D3 Bio (Wuxi) Co., LtdRecruitingAdvanced Solid Tumors With MAPK Pathway MutationsAustralia, China, United States
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Astellas Pharma Global Development, Inc.WithdrawnSubjects With NSCLC With an EGFR Activating Mutation
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Turning Point Therapeutics, Inc.TerminatedAdvanced Solid Tumor | Metastatic Solid Tumor | KRAS Mutation-Related TumorsUnited States
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Novartis PharmaceuticalsCompletedAdvanced Solid Tumors With Alterations of FGFR1, 2 and or 3 | Squamous Lung Cancer With FGFR1 Amplification | Bladder Cancer With FGFR3 Mutation or Fusion | Advanced Solid Tumors With FGFR1 Amplication | Advanced Solid Tumors With FGFR2 Amplication | Advanced Solid Tumors With FGFR3 MutationFrance, Spain, Taiwan, Germany, Netherlands, Singapore, United States, Australia, Korea, Republic of, Thailand, Israel, Italy, Turkey, Austria
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Taiho Oncology, Inc.TerminatedAdvanced or Metastatic Solid Tumors Irrespective of Gene Alterations | Advanced or Metastatic Solid Tumors With Germline PTEN Inactivating MutationsUnited States, United Kingdom, Austria, France
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Faeth TherapeuticsActive, not recruitingAdvanced Solid Tumor | PIK3CA Mutation | PTEN Loss of Function MutationUnited States
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AmgenActive, not recruitingAdvanced/Metastatic Solid Tumors With KRAS p.G12C MutationTaiwan, Hong Kong
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AnHeart Therapeutics Inc.RecruitingIDH1 Inhibitor AB-218 in Patients With Advanced IDH1 Mutant Cholangiocarcinoma and Other Solid TumorCholangiocarcinoma With IDH1 Mutation | Solid Tumors With IDH1 MutationChina
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BayerRecruitingLocally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene FusionUnited States, Austria, Denmark, Germany, Italy, Norway, Spain, United Kingdom, Brazil, Russian Federation, Switzerland, Taiwan, Canada, China, Australia, Greece, Belgium, Sweden, Korea, Republic of, France, Argentina, Finland, Ireland and more
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Frontier Medicines CorporationRecruitingColorectal Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Metastatic Solid Tumor | Solid Tumor, Adult | Unresectable Solid Tumor | KRAS G12C | Advanced Solid Tumors With KRAS G12C MutationsUnited States
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Jiangsu vcare pharmaceutical technology co., LTDCompletedLocally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene FusionChina
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Hacettepe UniversityThe Scientific and Technological Research Council of TurkeyCompletedProblem With Growth of an Infant
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Novartis PharmaceuticalsCompletedEstrogen Receptor Positive Breast Cancer | Advanced Solid Tumors With an Alteration of the PIK3CA GeneUnited States, Netherlands, Spain, Germany, United Kingdom
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BayerCompletedAdvanced or Recurrent Solid Tumor Harboring an NTRK Gene FusionJapan
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PlexxikonTerminatedSolid Tumor | Tenosynovial Giant Cell Tumor | Tumors of Any Histology With Activating Trk (NTRK) Point or NTRK Fusion MutationsUnited States
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Endeavor Biomedicines, Inc.Active, not recruitingSolid Tumors With PTCH1 Loss-of-function MutationsUnited States
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AstraZenecaDaiichi Sankyo Co., Ltd.Active, not recruitingAdvanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,BreastItaly, Spain, United States, France, Korea, Republic of, Japan, Canada, Denmark, Belgium
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Pasithea Therapeutics Corp.RecruitingAdvanced Solid Tumors | RAS Mutation | NF1 Mutation | RAF MutationUnited States
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BayerRecruitingAdvanced or Recurrent Solid Tumor Harboring an NTRK Gene FusionJapan
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BeiGeneCompletedFor Participants With Advanced Solid Tumors Failed With Previous Lines of TreatmentAustralia
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Nested Therapeutics, IncRecruitingGlioma | Melanoma | NSCLC | Oncology | Solid Tumor, Adult | MEK Mutation | RAF Gene Mutation | Ras (KRAS or NRAS) Gene Mutation | MAPK Pathway Gene MutationUnited States, Australia
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Chungbuk National University HospitalMerck KGaA, Darmstadt, GermanyRecruitingSolid Tumor | MET Amplification | MET Exon 14 Skipping MutationKorea, Republic of
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University of NebraskaAlegent Health Bergan Mercy Medical CenterCompletedProblem With Growth of an InfantUnited States
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Servier Bio-Innovation LLCInstitut de Recherches Internationales ServierNot yet recruitingLocally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen
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Gustave Roussy, Cancer Campus, Grand ParisRecruiting
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Peking University Third HospitalRecruitingProblem With Growth of an InfantChina
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University of Sao PauloCompletedTo Study the Influence of an Multifocal Intraocular Lens With Different Addition on Intermediate Visual AcuityBrazil
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Jason J. Luke, MDBristol-Myers Squibb; Agios Pharmaceuticals, Inc.CompletedGlioma | Advanced Solid Tumor | IDH1 MutationUnited States
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Assistance Publique - Hôpitaux de ParisCompletedPatients With Advanced Lymphoid Malignancies in the Absence of an HLA Identical or Mismatch DonorFrance
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ABM Therapeutics Shanghai Company LimitedRecruitingAdvanced Solid Tumor | BRAF V600 MutationChina
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ABM Therapeutics CorporationRecruitingAdvanced Solid Tumor | RAS Mutation | NF1 Mutation | RAF MutationUnited States
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Nobel BiocareUnknownHealthy Volunteers With Severely Resorbed Jaws in Need of an Implant Supported RestorationGermany
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Deciphera Pharmaceuticals LLCRecruitingMelanoma | Non-Small Cell Lung Cancer | Advanced Solid Tumor | Pancreatic Ductal Adenocarcinoma | BRAF Gene Mutation | RAS Mutation | NF1 Mutation | RAF Mutation | CRAF Gene MutationUnited States
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Rutgers, The State University of New JerseyMonell Chemical Senses CenterCompletedTreatment of Sweet Taste Receptors Without or With an Oral Rinse of Ibuprofen Solution in Healthy Participants | Treatment of Sweet Taste Receptors Without or With an Oral Rinse of Naproxen Solution in Healthy ParticipantsUnited States
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Taiho Oncology, Inc.TerminatedAdvanced Solid Tumors With HER2 Abnormalities | Advanced Solid Tumors With HER3 AbnormalitiesUnited States, Spain, France, United Kingdom
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University Health Network, TorontoRecruitingGlioma | Solid Tumor | Cholangiocarcinoma | IDH MutationCanada
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Relay Therapeutics, Inc.Active, not recruitingBreast Cancer | Advanced Breast Cancer | Metastatic Breast Cancer | Solid Tumor, Adult | HER2-negative Breast Cancer | Hormone Receptor Positive Tumor | Unresectable Solid Tumor | PIK3CA MutationUnited States
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Pamela MunsterNovartisWithdrawnLocally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Solid Tumors, Adult | HPV-Related Squamous Cell Carcinoma | Human Papillomavirus-Related Carcinoma | PIK3CA Mutation-Related Tumors | PIK3CA Mutation | Human Papillomavirus-Related Squamous Cell CarcinomaUnited States
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Relay Therapeutics, Inc.RecruitingBreast Cancer | Advanced Breast Cancer | Metastatic Breast Cancer | Solid Tumor, Adult | HER2-negative Breast Cancer | Unresectable Solid Tumor | PIK3CA MutationUnited States, Spain, France, Italy
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Ambrx, Inc.WithdrawnHER2 Mutation-Related Tumors | HER2 Amplified Solid TumorsUnited States
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Novartis PharmaceuticalsRecruitingBRAF V600E Mutation-positive Unresectable Advanced or Recurrent Solid TumorJapan
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Faculty Hospital Kralovske VinohradyCompletedPatients With an Aneurysm of Native Vascular Access Indicated for Surgical TreatmentCzechia
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Nantes University HospitalUnknownOcclusion of Bile Duct With an External Bile Diversion.France
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Shanghai Chest HospitalRecruitingMetastatic Cancer | Adenocarcinoma of Lung | Non-Small Cell Lung Cancer With EGFR Mutation | Locally Advanced Solid TumorChina
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Puma Biotechnology, Inc.TerminatedSolid Tumors Harboring Somatic HER2 or EGFR Exon 18 MutationsFrance, United States, Spain, Belgium, United Kingdom, Serbia, Australia, Israel, Canada, Denmark, Ireland, Italy, Korea, Republic of
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Institute FranciActive, not recruitingRehabilitation of Edentulous Area With an Implant Level Set-upItaly
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michal rollRecruitingSurgical Resection | The Aim of the Study is to Evaluate the Efficacy of Photodynamic Therapy as an | Adjuvant Therapy on the Clinical Outcome of Patients With Desmoid Tumors AfterIsrael
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Novartis PharmaceuticalsActive, not recruitingLocally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutationSpain, Italy, Austria, Netherlands, United Kingdom, Thailand, France, Belgium, China, Germany, Greece, Argentina, Turkey, Malaysia, Portugal, Brazil, United States, Hungary, India
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AmgenRecruitingAdvanced Solid Tumors | Kirsten Rat Sarcoma (KRAS) pG12C MutationUnited States, Italy, Taiwan, Spain, United Kingdom, Australia, Austria, Germany, Belgium, Japan, Netherlands, Korea, Republic of, Canada