Clinical Trials on Aortic Stenosis Symptomatic

Total 5375 results

Duke University
Gilead Sciences

Completed

Ranolazine for the Treatment of Chest Pain in HCM Patients (RHYME)

Hypertrophic Cardiomyopathy

United States
Meshalkin Research Institute of Pathology of Circulation

Completed

Surgical Treatment of Hypertrophic Obstructive Cardiomyopathy With Severe Mitral Insufficiency.

Hypertrophic Obstructive Cardiomyopathy

Russian Federation
Shaare Zedek Medical Center
Medtronic

Unknown

CRyo-Ablation to Treat Patients With HOCM. (CRASH)

HOCM, Hypertrophic Obstructive Cardiomyopathy
Hospital Universitari Son Dureta
Laboratorios BIOMED SA

Unknown

Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications (CALCIFICA)

Aortic Stenosis | Heart Valve Disease

Spain
Abbott Medical Devices

Completed

Trifecta™ Long Term Follow-Up (LTFU) Study

Aortic Valve Stenosis | Aortic Valve Insufficiency | Aortic Valve Incompetence | Aortic Valve Regurgitation

United States, Canada
Abbott Medical Devices

Completed

Aortic Valve Replacement With Trifecta(TM)

Aortic Valve Stenosis | Aortic Valve Insufficiency | Regurgitation, Aortic Valve | Aortic Valve Incompetence

United States
Abbott Medical Devices

Completed

An Observational, Prospective Evaluation of the Trifecta™ Valve

Aortic Valve Stenosis | Aortic Valve Insufficiency | Regurgitation, Aortic Valve | Aortic Valve Incompetence

Germany, Netherlands, France
C. R. Bard

Completed

Progel Vascular Sealant

Aortic Valve Stenosis | Aortic Valve Disorder | Aneurysm of Ascending Aorta | Bicuspid Valve Disorder

United States
Assistance Publique - Hôpitaux de Paris
Action Research Group

Not yet recruiting

Antagonization of Heparin With Protamine Sulfate After TAVI (ATLANTIS-Prota)

Aortic Valve Stenosis | Heart Valve Diseases
Shanghai MicroPort CardioFlow Medtech Co., Ltd.

Recruiting

VitaFlow™ Transcatheter Aortic Valve System Post-market Study-The LAUNCH Study

Aortic Valve Stenosis

China
Edwards Lifesciences

Active, not recruiting

The SAPIEN 3 Ultra System in Intermediate Risk Patients With Symptomatic, Severe Aortic Stenosis

Aortic Valve Stenosis

Canada, United Kingdom
Rennes University Hospital

Terminated

Randomized Study for the Optimal Treatment of Symptomatic Patients With Low Gradient Severe Aortic Valve Stenosis and Preserved Left Ventricular Ejection Fraction (ROTAS)

Aortic Valve Stenosis

France, Belgium
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Completed

Registry to Evaluate the Impact of a Valve Coordinator on Aortic Stenosis / TAVI Outcome - (German Pilot) (Coordinate)

Aortic Valve Stenosis

Germany
Nicolaus Copernicus University

Completed

Aortic Valve replAcement in eLective Patients From aOrtic Valve multiceNter Registry (AVALON)

Aortic Valve Stenosis
University of Oxford
British Heart Foundation

Active, not recruiting

Oxford - Fibrates in Aortic Stenosis (OxFAST)

Aortic Valve Stenosis

United Kingdom
Edwards Lifesciences

Completed

PREVAIL-20J - Transfemoral Placement of 20mm Aortic Balloon Expandable Transcatheter Valve Trial (PREVAIL-20J)

Aortic Valve Stenosis

Japan
Edwards Lifesciences

Completed

PREVAIL-J - Transfemoral & Transapical Placement of Aortic Balloon Expandable Transcatheter Valves Trial (Japan)

Aortic Valve Stenosis

Japan
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Completed

Study to Improve Outcomes in Aortic Stenosis

Aortic Valve Stenosis

France, Germany
Medtronic Cardiovascular

Completed

Clinical Evaluation of MDT-2111 in Subjects With Small Aortic Annuli and Symptomatic Severe Aortic Stenosis

Aortic Valve Stenosis

Japan
National Heart, Lung, and Blood Institute (NHLBI)
Medstar Washington Hospital Center

Withdrawn

Use of Cardiac-MRI to Predict Results for People With Severe Aortic Stenosis

Aortic Valve Stenosis
Medtronic Cardiovascular

Completed

Clinical Evaluation of MDT-2111 in Subjects With Symptomatic Severe Aortic Stenosis

Aortic Valve Stenosis

Japan
Assiut University

Unknown

Outcomes of Transcatheter Aortic Valve Implantation in Management of Severe Symptomatic Aortic Stenosis (TAVI)

Aortic Valve Stenosis
Maastricht University Medical Center

Completed

Biological Variation of Cardiac Biomarkers in Aortic Valve Stenosis

Aortic Valve Stenosis

Netherlands
Baylor Research Institute

Completed

Improving Echo Measurements in the Diagnosis of Aortic Stenosis

Aortic Valve Stenosis

United States
Aarhus University Hospital Skejby
Odense University Hospital; Danish Heart Foundation

Terminated

Transapical Transcatheter Treatment Versus Conventional Surgery in Patients With Native Aortic Valve Stenosis

Aortic Valve Stenosis

Denmark
Seoul National University Hospital

Unknown

PCSK9 Inhibitors in the Progression of Aortic Stenosis

Aortic Valve Stenosis

Korea, Republic of
Direct Flow Medical, Inc.

Unknown

Percutaneous Aortic Valve 18F System for the Treatment of Patients With Severe Aortic Stenosis

Aortic Valve Stenosis

Germany, United Kingdom, France, Italy, Luxembourg
Spectranetics Corporation

Completed

Valvuloplasty Scoring Balloon Catheter First-in-Man Study

Aortic Valve Stenosis

Canada
InCor Heart Institute

Completed

Microparticles in Severe Aortic Stenosis

Aortic Valve Stenosis

Brazil
Centro Cardiologico Monzino
Azienda Ospedaliera "Sant'Andrea"; Azienda Sanitaria Universitaria Giuliano...

Recruiting

Exercise Oxygen Kinetic and Cardiac Output in Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy | Cardiopulmonary Exercise Test | Cardiac Output Measurement

Italy
Imperial College London
University of Oxford; Barts & The London NHS Trust; Medtronic; Imperial College... and other collaborators

Recruiting

Prospective Evaluation Of Exercise-Induced Cardiac Conduction Instability In Predicting Ventricular Fibrillation Events In Hypertrophic Cardiomyopathy (PREDICTVFII)

Hypertrophic Cardiomyopathy

United Kingdom
Ya-Wei Xu

Completed

Prognostic Significance of CMD Assessed by IMR in HCM Patients (caIMR-HCM)

Coronary Cicrovascular Dysfunction | Hypertrophic Cardiomyopathy Patients
Xijing Hospital

Active, not recruiting

Impact of Liwen Procedure in Obstructive Hypertrophic Cardiomyopathy on Arrhythmias

Arrhythmia | Hypertrophic Cardiomyopathy

China
Michele De Bonis

Completed

Mitral Regurgitation in Hypertrophic Obstructive Cardiomyopathy: Fix it in a Simple, Effective and Durable Way!

Mitral Regurgitation | Hypertrophic Obstructive Cardiomyopathy

Italy
Tufts Medical Center

Completed

Clinical and Therapeutic Implications of Fibrosis in Hypertrophic Cardiomyopathy

Myocardial Fibrosis | Hypertrophic Cardiomyopathy

United States
Royal Brompton & Harefield NHS Foundation Trust
Acutus Medical

Unknown

HCM-AF Ablation With ACUTUS

Atrial Fibrillation | Hypertrophic Cardiomyopathy
Hospital Clinic of Barcelona

Unknown

CArdiac Desynchronization In Obstructive HCM, CARDIO-HCM (CARDIO-HCM)

Hypertrophic Obstructive Cardiomyopathy (HOCM)

Spain
Institute of Cardiology, Warsaw, Poland

Completed

Antiarrhythmic Therapy Versus Catheter Ablation for Atrial Fibrillation in Hypertrophic Cardiomyopathy

Atrial Fibrillation | Hypertrophic Cardiomyopathy

Poland
Friedrich-Alexander-Universität Erlangen-Nürnberg
University of Erlangen-Nürnberg Medical School

Recruiting

Detection of Aortic Stenosis With Smartphone Auscultation Using Machine Learning (HEARTBEAT-Pilot)

Aortic Valve Stenosis

Germany
Tempus AI
Medtronic

Not yet recruiting

Addressing Undertreatment and Health Equity in Aortic Stenosis Using an Integrated EHR Platform (ALERT)

Aortic Valve Stenosis
Venus MedTech (HangZhou) Inc.

Not yet recruiting

Venus-Vitae Pivotal Study Smart-Align Study

Aortic Valve Stenosis
McGill University Health Centre/Research Institute...

Recruiting

Translational-Omics in Aortic Stenosis (TOmAS) Biobank

Cardiovascular Diseases | Aortic Valve Stenosis

Canada
Valve Medical

Recruiting

FIH Study of the GEMINUS TAVI System in Patients With Severe Symptomatic Aortic Stenosis

Aortic Valve Stenosis

Israel
Shanghai NewMed Medical Co., Ltd.
West China Hospital; The General Hospital of Northern Theater Command

Recruiting

Prizvalve Pro™ Transcatheter Aortic Valve Replacement Study

Aortic Valve Stenosis

China
Duk-Woo Park, MD
CardioVascular Research Foundation, Korea; Daewoong Pharmaceutical Co. LTD.

Not yet recruiting

ENAVOgliflozin Outcome Trial in Patients With Severe Aortic Stenosis After Transcatheter Aortic Valve Replacement (ENAVO-TAVR)

Aortic Valve Stenosis

Korea, Republic of
Jessa Hospital

Recruiting

Outcome, Recuperation and Hemodynamics in Aortic Stenosis (PROCARE-AS)

Aortic Valve Stenosis

Belgium
Chengdu Silara Meditech Inc.

Recruiting

To Evaluate Safety and Effectiveness of Transcatheter Aortic Valve System in Patients With Severe Aortic Stenosis

Aortic Valve Stenosis

China
Meril Life Sciences Pvt. Ltd.

Recruiting

LANDMARK Trial: a Randomised Controlled Trial of Myval THV (LANDMARK)

Aortic Valve Stenosis

Sweden, Hungary, France, Belarus, Croatia, Germany, Netherlands, New Zealand, Poland, Portugal, Slovakia, Slovenia, Spain, Italy, Brazil, Estonia, Greece
Laval University
University Hospital, Brest

Recruiting

Multicenter Prospective Study of Low-Flow Low-Gradient Aortic Stenosis (TOPAS Study)

Aortic Valve Stenosis

United States, France, Austria, Belgium, Canada, Germany
IHF GmbH - Institut für Herzinfarktforschung
Yale University; Boston Scientific Group

Active, not recruiting

accuRate Evaluation of Benefit With Optimal Medical Treatment With or Without Transcatheter Valve Repair of PARADOXical Low Flow Low Gradient Aortic Stenosis (REBOOT-PARADOX)

Aortic Valve Stenosis

Germany

Clinical Trials on Aortic Stenosis Symptomatic

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