Clinical Trials on Aortic Stenosis

Total 5043 results

Shandong Suncadia Medicine Co., Ltd.

Recruiting

A Trial of HRS-1893 in Healthy Volunteers and Patients With Obstructive Hypertrophic Cardiomyopathy

Obstructive Hypertrophic Cardiomyopathy

China
Morten Steen Kvistholm Jensen
Odense University Hospital; Zealand University Hospital; Rigshospitalet, Denmark and other collaborators

Recruiting

Treatment Effects of Bisoprolol and Verapamil in Symptomatic Patients With Non-obstructive Hypertrophic Cardiomyopathy (TEMPO II)

Non-obstructive Hypertrophic Cardiomyopathy

Denmark
Imperial College London
British Heart Foundation

Recruiting

Electromechanically Optimised Right Ventricular Pacing In Hypertrophic Cardiomyopathy (EMORI-HCM) (EMORI-HCM)

Hypertrophic Cardiomyopathy | Hypertrophic Obstructive Cardiomyopathy

United Kingdom
St. Antonius Hospital
Erasmus Medical Center

Recruiting

Surgical Septal Myectomy vs Percutaneous Transluminal Alcohol Septal Ablation in Patients With Hypertrophic Obstructive Cardiomyopathy (AMARONE)

Hypertrophic Cardiomyopathy

Netherlands
Cytokinetics

Completed

Dose-finding Study to Evaluate the Safety, Tolerability, PK, and PD of CK-3773274 in Adults With HCM (REDWOOD-HCM)

Hypertrophic Cardiomyopathy (HCM)

United States, Spain, Italy, Netherlands
University Hospital, Motol

Completed

Effect of Metoprolol in Post Alcohol Septal Ablation Patients With Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy

Czechia
MyoKardia, Inc.

Completed

Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy (EXPLORER-HCM)

Obstructive Hypertrophic Cardiomyopathy

United States, France, Germany, Czechia, Spain, Belgium, Denmark, Portugal, Netherlands, Israel, Poland, United Kingdom, Italy
The Cleveland Clinic

Completed

Conduction Abnormalities With Severe Aortic Stenosis Before and After Transcatheter Aortic Valve Replacement

Bradycardia

United States
Assiut University
Manchester University NHS Foundation Trust

Unknown

Early Outcomes of Concomitant Transcatheter Aortic Valve Implantation and Off-pump Coronary Artery Bypass Grafting in Management of Severe Symptomatic Aortic Stenosis and Coronary Artery Disease

Coronary Artery Disease | Aortic Valve Disease

Egypt
Tomsk National Research Medical Center of the Russian...

Completed

Mitral Valve in Hypertrophic Cardiomyopathy

Hypertrophic Obstructive Cardiomyopathy

Russian Federation
University Hospital, Strasbourg, France

Not yet recruiting

Expression of Sodium-glucose Co-transporter 2 in Human Heart (SGLT2-MICRA)

Aortic Valve Stenosis

France
University of Virginia

Recruiting

Platelet Adhesion in the Pathobiology of Aortic Stenosis

Aortic Valve Stenosis

United States
University Hospital, Lille
Ministry of Health, France

Recruiting

Balloon-Expandable Versus Self-expanding Transcatheter Heart Valve for Treatment of Symptomatic Native Aortic Valve Stenosis (BEST) (BEST)

Aortic Valve Stenosis

France
Radboud University Medical Center

Recruiting

Myeloid Cells in Aortic Valve Stenosis (MIRACLE)

Aortic Valve Stenosis | Aortic Valve Disease

Netherlands
Meril Life Sciences Pvt. Ltd.

Recruiting

Myval Global Study of Myval™ THV Series Implanted in Patients With Native Severe Aortic Valve Stenosis.

Aortic Valve Stenosis

Slovenia, Spain, Turkey, Italy, Netherlands, Estonia, Poland
University Hospital, Rouen
University Hospital, Caen

Recruiting

Measurement of Myocardial Stiffness Using Elastometry in Patients With Aortic Stenosis (ELASTOP-AS)

Aortic Valve Stenosis

France
Catharina Ziekenhuis Eindhoven

Active, not recruiting

Stress Aortic Valve Index for Assessing Risk in Aortic Valve Stenosis Patients (SAVI-AoS)

Aortic Valve Stenosis

Denmark, Netherlands, United States
Cardiawave SA

Completed

Valvosoft First-In-Man Study in Severe Symptomatic Aortic Stenosis

Aortic Valve Stenosis

France, Netherlands
Cardiawave SA

Active, not recruiting

Valvosoft First-In-Human Study in Severe Symptomatic Aortic Stenosis

Aortic Valve Stenosis

Serbia
Aarhus University Hospital Skejby

Completed

Pressure Gradient vs. Flow Relationships in Patients With Symptomatic Valvular Aortic Stenosis (PREFLOW)

Aortic Valve Stenosis

Denmark
Edwards Lifesciences

Active, not recruiting

ExCEED: CENTERA THV System in Intermediate Risk Patients Who Have Symptomatic, Severe, Calcific, Aortic Stenosis

Aortic Valve Stenosis

United States
University Hospital Inselspital, Berne

Completed

Morbidity and Mortality Due to Deferral of Aortic Valve Replacement in Patients With Severe Aortic Stenosis (AS DEFER)

Aortic Valve Stenosis

Switzerland
Heinrich-Heine University, Duesseldorf

Completed

Evaluation of BAV in Different Hemodynamic Entities of Severe AS (BAV)

Aortic Valve Stenosis

Germany
Henry Ford Health System

Withdrawn

CPX in Paradoxical Low Flow Aortic Stenosis

Aortic Valve Stenosis

United States
University Hospital Inselspital, Berne

Completed

Volume Challenge Added to DSE in the Diagnosis of Severe LFLGAS (FLOW-AS)

Aortic Valve Stenosis

Switzerland
German Heart Institute
Charite University, Berlin, Germany

Unknown

Validation of a Novel, Non-Dimensional Approach for Estimation of Pressure Gradients in Aortic Stenosis (AVD-PowerLaw)

Aortic Valve Stenosis

Germany
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Completed

Quality of Care in AS IMPULSE Study (IMPULSE)

Aortic Valve Stenosis

United Kingdom, Germany, Switzerland, Austria, France, Italy, Netherlands, Czechia, Spain
Rennes University Hospital

Completed

Low Flow Low Gradient Aortic Stenosis Relevance of the (re)Search for a Contractile Reserve (LOWAS)

Aortic Valve Stenosis

France
AORTICA Group

Terminated

Randomized Study to Evaluate the Efficacy of Fluvastatin on Inflammatory Markers in Patients With Aortic Stenosis.

Aortic Valve Stenosis

Spain
Biotronik AG
Medstar Health Research Institute

Unknown

BIOVALVE - I / II Clincial Investigation (BIOVALVE)

Aortic Valve Stenosis | Heart Valve Diseases

Belgium, Germany, Switzerland, Netherlands
The Cleveland Clinic
Pfizer

Terminated

The Effect of Lipitor on Aortic Stenosis

Aortic Valve Stenosis

United States
Seung-Jung Park
CardioVascular Research Foundation, Korea

Withdrawn

TRANscatheter or SurgIcal Aortic Valve ReplacemenT in All-Comers With Severe Aortic Valve Stenosis (TRANSIT)

Aortic Valve Stenosis

Korea, Republic of
Direct Flow Medical, Inc.

Unknown

A Registry to Evaluate the Direct Flow Medical Transcatheter Aortic Valve System (DISCOVER)

Aortic Valve Stenosis

Germany, Italy
Friedrich-Alexander-Universität Erlangen-Nürnberg
University of Erlangen-Nürnberg Medical School

Recruiting

Detection of Aortic Stenosis With Smartphone Auscultation Using Machine Learning (HEARTBEAT-Pilot)

Aortic Valve Stenosis

Germany
Tempus AI
Medtronic

Not yet recruiting

Addressing Undertreatment and Health Equity in Aortic Stenosis Using an Integrated EHR Platform (ALERT)

Aortic Valve Stenosis
Venus MedTech (HangZhou) Inc.

Not yet recruiting

Venus-Vitae Pivotal Study Smart-Align Study

Aortic Valve Stenosis
McGill University Health Centre/Research Institute...

Recruiting

Translational-Omics in Aortic Stenosis (TOmAS) Biobank

Cardiovascular Diseases | Aortic Valve Stenosis

Canada
Valve Medical

Recruiting

FIH Study of the GEMINUS TAVI System in Patients With Severe Symptomatic Aortic Stenosis

Aortic Valve Stenosis

Israel
Shanghai NewMed Medical Co., Ltd.
West China Hospital; The General Hospital of Northern Theater Command

Recruiting

Prizvalve Pro™ Transcatheter Aortic Valve Replacement Study

Aortic Valve Stenosis

China
Duk-Woo Park, MD
CardioVascular Research Foundation, Korea; Daewoong Pharmaceutical Co. LTD.

Not yet recruiting

ENAVOgliflozin Outcome Trial in Patients With Severe Aortic Stenosis After Transcatheter Aortic Valve Replacement (ENAVO-TAVR)

Aortic Valve Stenosis

Korea, Republic of
Jessa Hospital

Recruiting

Outcome, Recuperation and Hemodynamics in Aortic Stenosis (PROCARE-AS)

Aortic Valve Stenosis

Belgium
Chengdu Silara Meditech Inc.

Recruiting

To Evaluate Safety and Effectiveness of Transcatheter Aortic Valve System in Patients With Severe Aortic Stenosis

Aortic Valve Stenosis

China
Meril Life Sciences Pvt. Ltd.

Recruiting

LANDMARK Trial: a Randomised Controlled Trial of Myval THV (LANDMARK)

Aortic Valve Stenosis

Sweden, Hungary, France, Belarus, Croatia, Germany, Netherlands, New Zealand, Poland, Portugal, Slovakia, Slovenia, Spain, Italy, Brazil, Estonia, Greece
Laval University
University Hospital, Brest

Recruiting

Multicenter Prospective Study of Low-Flow Low-Gradient Aortic Stenosis (TOPAS Study)

Aortic Valve Stenosis

United States, France, Austria, Belgium, Canada, Germany
IHF GmbH - Institut für Herzinfarktforschung
Yale University; Boston Scientific Group

Active, not recruiting

accuRate Evaluation of Benefit With Optimal Medical Treatment With or Without Transcatheter Valve Repair of PARADOXical Low Flow Low Gradient Aortic Stenosis (REBOOT-PARADOX)

Aortic Valve Stenosis

Germany
Shanghai NewMed Medical Co., Ltd.

Active, not recruiting

PrizValve® Transcatheter Aortic Valve Replacement Study

Aortic Valve Stenosis

China
Optimapharm
Edwards Lifesciences

Active, not recruiting

RHEIA (Randomized researcH in womEn All Comers With Aortic Stenosis) (RHEIA)

Aortic Valve Stenosis | Heart Valve Diseases

United Kingdom, Italy, Germany, France, Austria, Switzerland, Finland, Czechia, Belgium, Netherlands, Cyprus, Ireland
Massachusetts General Hospital
University of Colorado, Denver

Completed

Impact of a Patient Decision Aid for Treatment of Aortic Stenosis

Aortic Valve Stenosis

United States
Shanghai MicroPort CardioFlow Medtech Co., Ltd.

Unknown

VitaFlow™ Transcatheter Aortic Valve System Pre-market Trial

Aortic Valve Stenosis

China
Bassett Healthcare
Baylor University

Completed

Podocan and Wnt Pathway in Left Ventricular Remodeling of Aortic Stenosis

Aortic Valve Stenosis

United States

Clinical Trials on Aortic Stenosis

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