Clinical Trials on Aphasia, Primary Progressive

Total 61568 results

Pfizer

Completed

Registry For Temsirolimus, Sunitinib, And Axitinib Treated Patients With Metastatic Renal Cell Carcinoma (mRCC), Mantle Cell Lymphoma (MCL), And Gastro-Intestinal Stroma Tumor (GIST) [STAR-TOR] (STAR-TOR)

Lymphoma, Mantle-Cell | Carcinoma, Renal Cell, Advanced | Gastrointestinal Stroma Tumors

Germany
Mucpharm Pty Ltd
St George Hospital, Australia; Mobius Medical Pty Ltd.

Completed

Nebulised BromAc in Healthy Volunteers

COVID-19 Pneumonia | COVID-19 Acute Respiratory Distress Syndrome | Bromelains Adverse Reaction | Acetylcysteine Adverse Reaction | Mucus; Plug

Australia
Wake Forest University Health Sciences

Completed

FGF23 and Angiotensin-(1-7) in Hypophosphatemia (GAP) (GAP)

Hypophosphatemia | X-linked Hypophosphatemia | Left Ventricular Hypertrophy | Renin-angiotensin System

United States
Nagla Abdel Karim

Completed

Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid Tumors

Carcinoma, Non-Small-Cell Lung | Ovarian Cancer | Thymoma | Mesothelioma | Bladder Cancer | Peritoneal Cancer | Thymus Cancer | Uterine Cervical Cancer

United States
Memorial Sloan Kettering Cancer Center
Pediatric Brain Tumor Consortium

Terminated

A Study of the Effect of Blood Stem Cell Transplant After Chemotherapy Alone in Patients With Fanconi Anemia

Fanconi Anemia | Myelodysplastic Syndrome (MDS) | Acute Myelogenous Leukemia (AML)

United States
National Cancer Institute (NCI)

Withdrawn

Aerosolized Azacytidine as Epigenetic Priming for Bintrafusp Alfa-Mediated Immune Checkpoint Blockade in Patients With Unresectable Pulmonary Metastases From Sarcomas, Germ Cell Tumors, or Epithelial Malignancies

Pulmonary Metastases | Germ Cell Tumors | Sarcomas | Melanomas | Epithelial Malignancies (Excluding Lung and Renal Cell Carcinomas)

United States
Institut de cancérologie Strasbourg Europe
LEAF4Life, Inc.

Completed

A Study of Liposomal Trans Crocetin, LEAF-4L6715, in Patients With Acute Respiratory Distress Syndrome Due to COVID-19, Sepsis or Other Causes

Acute Respiratory Distress Syndrome | COVID19, Sepsis or Other Causes

France
Loma Linda University

Withdrawn

Tazemetostat for the Treatment of Moderate to Severe COVID-19 Infection (IST)

Cytokine Release Syndrome | COVID-19 Acute Respiratory Distress Syndrome
University of California, San Francisco

Completed

Study of Clofarabine and Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation (HCT)

Sickle Cell Disease | Hemoglobinopathies | Thalassemia | Hematologic Malignancies | Immunodeficiencies | Fanconi's Anemia | Nonmalignant Diseases | Genetic Inborn Errors of Metabolism

United States
University of California, San Francisco
Thrasher Research Fund

Completed

Study of Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation (HCT)

Sickle Cell Disease | Hemoglobinopathies | Fanconi Anemia | Thalassemia | Hematologic Malignancies | Immunodeficiencies | Nonmalignant Diseases | Genetic Inborn Errors of Metabolism

United States
Shiphrah Biomedical Inc.
University of South Australia

Terminated

UniSA BackOff! Study: Adelaide PrenaBelt Trial

Pregnancy Complications | Fetal Growth Retardation | Sleep-Disordered Breathing | Infant, Very Low Birth Weight | Stillbirth | Infant, Small for Gestational Age | Fetal Hypoxia | Infant, Low Birth Weight

Australia
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Cabazitaxel With or Without Carboplatin in Treating Patients With Previously Treated Metastatic Castration-Resistant Prostate Cancer

Lymphadenopathy | Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Prostate Adenocarcinoma | Castration Levels of Testosterone | Prostate Carcinoma Metastatic in the Bone | Prostate Small Cell Carcinoma

United States
The University of Texas Health Science Center at...
The Claude D. Pepper Older Americans Independence Centers

Withdrawn

Effects of mTOR Inhibition With Sirolimus (RAPA) in Patients With COVID-19 to Moderate the Progression of ARDS (RAPA-CARDS)

Respiratory Failure | Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) | Sars-CoV2

United States
Amyndas Pharmaceuticals S.A.

Unknown

A Study of the C3 Inhibitor AMY-101 in Patients With ARDS Due to COVID-19 (SAVE) (SAVE)

Acute Respiratory Distress Syndrome Due to SARS-CoV-2 Infection (Severe COVID19)
Novita Pharmaceuticals, Inc.
Translational Drug Development

Completed

Clinical Trial of Metastasis Inhibitor NP-G2-044 in Patients With Advanced or Metastatic Treatment-Refractory Solid Tumor Malignancies

Breast Cancer | Lung Cancer | Prostate Cancer | Colon Cancer | Pancreas Cancer | Liver Cancer | Ovary Cancer | Esophagus Cancer | Advanced or Metastatic Treatment-refractory Solid Tumor Malignancies

United States
Brigham and Women's Hospital

Completed

Remote Physician Care for Home Hospital Patients

Heart Failure | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Infection | Gout Flare | Hypertensive Urgency | Anticoagulants; Increased | Atrial Fibrillation Rapid

United States
Central Hospital, Nancy, France

Unknown

Effect of Corticosteroid Treatment on Prognosis in ARDS Secondary to Covid-19 (CoCovSDRA)

Acute Respiratory Distress Syndrome Secondary to Covid-19

France
Memorial Sloan Kettering Cancer Center

Completed

Continued Access to RXDX-105

Ovarian Cancer | Non Small Cell Lung Cancer | RET Gene Mutation | BRAF Gene Mutation

United States
Koç University

Completed

Physical Rehabilitation in ICU in ARDS Patients With COVID-19

COVID-19 | Rehabilitation | Acute Respiratory Distress Syndrome | Intensive Care Unit Acquired Weakness | Critical Illness Polyneuromyopathy

Turkey
AstraZeneca

Completed

AZD8186 First Time In Patient Ascending Dose Study

Advanced Castrate-resistant Prostate Cancer CRPC | Squamous Non-Small Cell Lung Cancer sqNSCLC | Triple Negative Breast Cancer TNBC

Spain, Canada, United States, United Kingdom
University of Southern California
National Cancer Institute (NCI)

Terminated

Exercise in Targeting Metabolic Dysregulation in Stage I-III Breast or Prostate Cancer Survivors

Obesity | Overweight | Sedentary Lifestyle | Stage I Breast Cancer | Cancer Survivor | Prostate Carcinoma | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer | Stage... and other conditions

United States
Hospital Clinic of Barcelona

Unknown

Dexmedetomidine to Improve Outcomes of ARDS in Critical Care COVID-19 Patients (COVID-DEX)

Inflammation | Acute Respiratory Distress Syndrome | Dexmedetomidine | Cytokine Storm | Delirium, Emergence
National Cancer Institute (NCI)

Completed

Gemcitabine Hydrochloride and Eribulin Mesylate in Treating Patients With Bladder Cancer That is Advanced or Cannot Be Removed by Surgery

Metastatic Urethral Carcinoma | Stage III Bladder Urothelial Carcinoma AJCC v6 and v7 | Stage III Ureter Cancer AJCC v7 | Stage III Urethral Cancer AJCC v7 | Stage IV Bladder Urothelial Carcinoma AJCC v7 | Stage IV Ureter Cancer AJCC v7 | Stage IV Urethral Cancer AJCC v7 | Ureter Urothelial Carcinoma and other conditions

United States, Canada
Baylor Research Institute
Shire

Unknown

A One Visit Follow Up of Adults With Fabry Disease Who Started Long-term Enzyme Replacement Therapy As Children

Quality of Life | Renal Insufficiency | Cardiac Event

United States
Spectrum Dynamics
University Hospital, Caen

Completed

Data Collection Study for the Spectrum Dynamics Multi-purpose CZT SPECT Camera

Heart Diseases | Parkinson Disease | Bone Diseases | Dementia | Pulmonary Hypertension | Pulmonary Embolism | Renal Disease | Bone Fracture | Paget Disease | Bone Lesion

France
Albert Einstein College of Medicine

Completed

Effect of Obstructive Sleep Apnea Syndrome on Insulin Sensitivity and Cardiovascular Risk in PCOS Adolescents

Obstructive Sleep Apnea Syndrome | Polycystic Ovary Syndrome | Sleep Apnea

United States
Natera, Inc.

Completed

Development of Non-invasive Prenatal Test for Microdeletion and Other Genetic Syndromes Based on Cell Free DNA (Microdel Triad)

Trisomy 21 | Trisomy 18 | Trisomy 13 | Sex Chromosome Abnormalities | Microdeletion Syndromes

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Adrenal Hyperplasia Among Young People With PCOS

Obesity | Hyperandrogenism | Polycystic Ovarian Syndrome | Oligomenorrhea | Adrenal Hyperplasia

United States
University of Washington
Patient-Centered Outcomes Research Institute

Completed

Improving Communication About Serious Illness (ICSI)

End Stage Liver Disease | Heart Failure | Critical Illness | Lung Neoplasms | Neoplasm Metastasis | Pulmonary Disease, Chronic Obstructive | Kidney Failure, Chronic | Communication | Chronic Disease | Palliative Care | Advance Care Planning | Terminal Care

United States
InSightec

Completed

Study Comparing the Safety and Effectiveness of Magnetic Resonance Guided Focused Ultrasound (MRgFUS) and External Beam Radiation (EBRT) for Treatment of Metastatic Bone Tumors and Multiple Myeloma

Pain | Bone Cancer | Bone Metastases

Taiwan
National Cancer Institute (NCI)

Completed

VEGF Trap and Docetaxel in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer

Fallopian Tube Cancer | Recurrent Ovarian Epithelial Cancer | Malignant Tumor of Peritoneum

United States
National Cancer Institute (NCI)

Completed

A Phase 1, Dose Escalation Study of the Safety, Tolerability, and Pharmacokinetics of Intravenous Dimethane Sulfonate (DMS612) in Advanced Malignancies

Renal Cell Carcinoma | Breast Cancer | Lung Cancer | Non-Hodgkin Lymphoma | Colon Cancer

United States
Simon Fraser University
Canadian Institutes of Health Research (CIHR); Michael Smith Foundation for...

Completed

Trial of an Internet-based Platform for Managing Chronic Diseases at a Distance (iCDM)

Heart Failure | Diabetes | Chronic Obstructive Pulmonary Disease | Chronic Kidney Disease | Ischemic Heart Disease

Canada
National Cancer Institute (NCI)

Completed

Triapine, Cisplatin, and Radiation Therapy in Treating Patients With Cervical Cancer or Vaginal Cancer

Recurrent Cervical Cancer | Recurrent Vaginal Cancer | Stage IB Cervical Cancer | Stage II Vaginal Cancer | Stage IIA Cervical Cancer | Stage IIB Cervical Cancer | Stage III Cervical Cancer | Stage III Vaginal Cancer | Stage IVA Cervical Cancer | Stage IVA Vaginal Cancer | Stage IVB Cervical Cancer | Stage IVB... and other conditions

United States
Bispebjerg Hospital
The Danish Council for Strategic Research

Completed

D-tecting Disease - From Exposure to Vitamin D During Critical Periods of Life (D-tect)

Obesity | Diabetes Mellitus | Cancer | Arthritis | Vitamin D Deficiency | Asthma | Pregnancy Complications | Tooth Diseases | Birth Weight | Pre-Eclampsia | Mental Disorder | Congenital Disorders | Bone Fracture | Birth Disorder

Denmark
Assaf-Harofeh Medical Center

Unknown

A Phase II of Nivolumab Plus Ipilimumab in Non-resectable Sarcoma and Endometrial Carcinoma

Soft Tissue Sarcoma | Osteosarcoma | Chondrosarcoma | Bone Sarcoma | Desmoplastic Small Round Cell Tumor | Gastrointestinal Stromal Sarcoma | Ewing's Tumor Metastatic | Ewing's Tumor Recurrent
Hannah Brown Amoakoh
University of Ghana; Ghana Health Services

Completed

Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in Ghana (Accelerate)

Eclampsia | Asphyxia | Neonatal Jaundice | Postpartum Haemorrhage | Pre-eclampsia | Maternal Death | Neonatal Sepsis | Neonatal Death | Pregnancy Induced Hypertension | Puerperal Sepsis

Ghana
University of Colorado, Denver

Terminated

INR-Triggered Transfusion In GI Bleeders From ER (I-TRIGER)

Liver Diseases | Respiratory Distress Syndrome, Adult | Gastrointestinal Hemorrhage | Transfusion Related Lung Injury

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Completed

Interferon Alfa in Treating Patients With Stage IV Solid Tumors, Lymphoma, or Myeloma (IFNa)

Melanoma | Sarcoma | Lymphoma | Kidney Cancer | Breast Cancer | Multiple Myeloma | Unspecified Adult Solid Tumor, Protocol Specific

United States
Gynecologic Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Completed

Comparison of Two Combination Chemotherapy Regimens Plus Radiation Therapy in Treating Patients With Stage III or Stage IV Endometrial Cancer

Stage III Uterine Corpus Cancer | Endometrial Clear Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Adenocarcinoma | Endometrial Adenosquamous Carcinoma | Endometrial Endometrioid Adenocarcinoma, Variant With Squamous Differentiation

United States
Genzyme, a Sanofi Company
CRL/Medinet

Terminated

Severe Renal Disease Study in Fabry Patients Treated With Fabrazyme

Fabry Disease | Chronic Kidney Disease, Stage IV (Severe)

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Wilm's Tumor 1 (WT1) Peptide Vaccine for High Risk Hematologic Malignancy

Myelodysplastic Syndrome | Acute Myeloid Leukemia (AML) | Chronic Myeloid Leukemia (CML)

United States
All India Institute of Medical Sciences, New Delhi

Unknown

Sleep Quality in Pregnancy and Its Impact on Pregnancy Outcomes

Obstructive Sleep Apnea | Infant, Very Low Birth Weight | Pregnancy Induced Hypertension | High-Risk Pregnancy | Restless Leg Syndrome

India
Michael Morse, MD

Terminated

A Phase I Study of WT1 Peptides to Induce Anti-Leukemia Immune Responses Following Transplantation (WT-1)

Acute Lymphoblastic Leukemia (ALL) | Myelodysplastic Syndrome (MDS) | Acute Myelogenous Leukemia (AML) | B Cell Malignancies | Chronic Myelogenous Leukemia (CML)

United States
Bristol-Myers Squibb

Completed

Pharmacokinetic Study of BMS-914143 in Participants With Normal Renal Function and Mild, Moderate, Severe and End-stage Renal Dysfunction (PK)

Chronic Hepatitis C Virus Infection | Chronic Hepatitis B Virus Infection

United States
University of Kentucky

Completed

Phase I/II Study of Escalating-Dose Melphalan w/Autologous SCS & Amifostine Cytoprotect

Sarcoma | Lymphoma | Leukemia | Breast Cancer | Ovarian Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Neuroblastoma

United States
Genentech, Inc.

Completed

Bone Mineral Density (BMD) in Adolescents With Growth Hormone Deficiency (GHD)

Dwarfism, Pituitary | Turner Syndrome
Northside Hospital, Inc.
Blood and Marrow Transplant Group of Georgia

Completed

Early Administration of ATG Followed by Cyclophosphamide, Busulfan and Fludarabine Before a Donor Stem Cell Transplant in Patients With Hematological Cancer

Lymphoma | Kidney Cancer | Myelodysplastic Syndromes | Leukemia | Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases

United States
University of Michigan Rogel Cancer Center
National Cancer Institute (NCI)

Completed

UMCC 003 Cancer-Related Protein Biomarkers in Blood and Tumor Tissue of Patients With Cancer (IRB 2000-294)

Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Liver Cancer
University Hospital Inselspital, Berne
Merck Sharp & Dohme LLC; Pfizer

Completed

Prevalence of Sexually Transmitted Infections (STIs) in HIV-infected Patients (CTNG)

HIV Infections | Herpes Simplex | Chlamydia Trachomatis | Neisseria Gonorrhoeae

Switzerland

Clinical Trials on Aphasia, Primary Progressive

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